1 | MYC, PIM2, USP27X
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| Phosphorylation of USP27X by PIM2 promotes glycolysis and breast cancer progression via deubiquitylation of MYC.
|
| Han X, Ren C, Lu C, Jiang A, Wang X, Liu L, Yu Z.
|
| Oncogene. Aug;43(33):2493-2503. doi: 10.1038/s41388-024-03097-y. Epub 2024 Jul 5. 2024
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2 | MYC, TRIM55
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| TRIM55 inhibits colorectal cancer development via enhancing protein degradation of c-Myc.
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| Lin M, Fang Z, Lin X, Zhou W, Wang Y, Han S, Ye M, Zhu F.
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| Cancer Med. Jun;12(12):13511-13521. doi: 10.1002/cam4.6020. Epub 2023 May 22. 2023
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3 | MYC, UPK1B
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| UPK1B promoted the invasion and stem cell characteristics of non-small cell lung cancer cells by modulating c-myc/Sox4 axis.
|
| Liu Y, Ding L, Li C, Heng L, Chen J, Hou Y.
|
| Tissue Cell. Dec;85:102250. doi: 10.1016/j.tice.2023.102250. Epub 2023 Oct 19. 2023
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4 | CDKN1A, FUBP1, FUSE, MYC
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| Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1
|
| Ni X, Knapp S, Chaikuad A.
|
| Sci Rep Aug 10;10(1):13459. doi: 10.1038/s41598-020-69832-z. 2020
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5 | MTOR, MYC, SLC1A5
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| SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
|
| Zhao X, Petrashen AP, Sanders JA, Peterson AL, Sedivy JM.
|
| Aging Cell ging Cell. 2019 Mar 25:e12947. doi: 10.1111/acel.12947. [Epub ahead of print]
2019
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6 | MYC, SMARCB1
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| Inhibition of MYC by the SMARCB1 tumor suppressor.
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| Weissmiller AM, Wang J, Lorey SL, Howard GC, Martinez E, Liu Q, Tansey WP.
|
| Nat Commun 10(1):2014. doi: 10.1038/s41467-019-10022-5.
2019
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7 | LDHA, MTA1, MYC
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| MTA1 coregulator regulates LDHA expression and function in breast cancer.
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| Guddeti RK, Bali P, Karyala P, Pakala SB.
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| Biochem Biophys Res Commun 520(1):54-59. doi: 10.1016/j.bbrc.2019.09.078. Epub 2019 Sep 27.
2019
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8 | MYC, PKD1
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| c-Myc is a regulator of the PKD1 gene and PC1-induced pathogenesis
|
| Parrot C, Kurbegovic A, Yao G, Couillard M, Côté O, Trudel M.
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| Hum Mol Genet. Mar 1;28(5):751-763. doi: 10.1093/hmg/ddy379. 2019
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9 | MYC, ZNF322
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| Oncogenic zinc finger protein ZNF322A promotes stem cell-like properties in lung cancer through transcriptional suppression of c-Myc expression.
|
| Jen J, Liu CY, Chen YT, Wu LT, Shieh YC, Lai WW, Wang YC.
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| Cell Death Differ. Jul;26(7):1283-1298. doi: 10.1038/s41418-018-0204-6. Epub 2018 Sep 26. 2019
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10 | MYC, TRIM32, USP7
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| A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification.
|
| Nicklas S, Hillje AL, Okawa S, Rudolph IM, Collmann FM, van Wuellen T, Del Sol A, Schwamborn JC.
|
| Cell Death Differ ell Death Differ. 2018 Jun 13. doi: 10.1038/s41418-018-0144-1. [Epub ahead of print]
2018
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11 | MYC, SENP1
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| SUMO protease SENP1 deSUMOylates and stabilizes c-Myc.
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| Sun XX, Chen Y, Su Y, Wang X, Chauhan KM, Liang J, Daniel CJ, Sears RC, Dai MS.
|
| Proc Natl Acad Sci U S A 115(43):10983-10988. doi: 10.1073/pnas.1802932115. Epub 2018 Oct 10.
2018
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12 | MYC, SPOP
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| SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein.
|
| Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, Foley C, Dong B, Zhang L, Kwon OJ, Shah SS, Bolaki M, Xin L, Ittmann M, O'Malley BW, Coarfa C, Mitsiades N.
|
| Oncogene ncogene. 2017 Apr 17. doi: 10.1038/onc.2017.80. [Epub ahead of print]
2017
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13 | MYC, PIAS1
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| PIAS1 Promotes Lymphomagenesis through MYC Upregulation.
|
| Rabellino A, Melegari M, Tompkins VS, Chen W, Van Ness BG, Teruya-Feldstein J, Conacci-Sorrell M, Janz S, Scaglioni PP.
|
| Cell Rep 15(10):2266-2278. doi: 10.1016/j.celrep.2016.05.015. Epub 2016 May 26.
2016
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14 | MYC, SMARCB1
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| MYC interaction with the tumor suppressive SWI/SNF complex member INI1 regulates transcription and cellular transformation.
|
| Stojanova A, Tu WB, Ponzielli R, Kotlyar M, Chan PK, Boutros PC, Khosravi F, Jurisica I, Raught B, Penn LZ.
|
| Cell Cycle 15(13):1693-705. doi: 10.1080/15384101.2016.1146836. Epub 2016 Jun 7.
2016
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15 | MYC, PLSCR1
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| Two c-Myc binding sites are crucial in upregulating the expression of human phospholipid scramblase 1 gene.
|
| Vinnakota JM, Gummadi SN.
|
| Biochem Biophys Res Commun 469(3):412-7. doi: 10.1016/j.bbrc.2015.11.131. Epub 2015 Dec 8.
2016
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16 | BRD9, MYC
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| Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition.
|
| Hohmann AF, Martin LJ, Minder JL, Roe JS, Shi J, Steurer S, Bader G, McConnell D, Pearson M, Gerstberger T, Gottschamel T, Thompson D, Suzuki Y, Koegl M, Vakoc CR.
|
| Nat Chem Biol. Sep;12(9):672-9. doi: 10.1038/nchembio.2115. Epub 2016 Jul 4 2016
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17 | MYC, SMARCAL1
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| SMARCAL1 Negatively Regulates C-Myc Transcription By Altering The Conformation Of The Promoter Region.
|
| Sharma T, Bansal R, Haokip DT, Goel I, Muthuswami R.
|
| Sci Rep 5:17910. doi: 10.1038/srep17910.
2015
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18 | MYC, USP36
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| Deubiquitinating c-Myc: USP36 steps up in the nucleolus.
|
| Sun XX, Sears RC, Dai MS.
|
| Cell Cycle 14(24):3786-93. doi: 10.1080/15384101.2015.1093713.
2015
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19 | MYC, USP36
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| The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc.
|
| Sun XX, He X, Yin L, Komada M, Sears RC, Dai MS.
|
| Proc Natl Acad Sci U S A 112(12):3734-9. doi: 10.1073/pnas.1411713112. Epub 2015 Mar 9.
2015
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20 | MYC, PLD6
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| A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer
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| von Eyss B, Jaenicke LA, Kortlever RM, Royla N, Wiese KE, Letschert S, McDuffus LA, Sauer M, Rosenwald A, Evan GI, Kempa S, Eilers M
|
| Cancer Cell. Dec 14;28(6):743-757. doi: 10.1016/j.ccell.2015.10.013. 2015
|
21 | KIF5B, MYC
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| Transport of c-MYC by Kinesin-1 for proteasomal degradation in the cytoplasm.
|
| Lee CM.
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| Biochim Biophys Acta 1843(9):2027-36. doi: 10.1016/j.bbamcr.2014.05.001. Epub 2014 May 10.
2014
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22 | EIF2AK2, MYC
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| Identification of the PKR nuclear interactome reveals roles in ribosome biogenesis, mRNA processing and cell division.
|
| Blalock WL, Piazzi M, Bavelloni A, Raffini M, Faenza I, D'Angelo A, Cocco L.
|
| J Cell Physiol 229(8):1047-60. doi: 10.1002/jcp.24529.
2014
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23 | EYA1, MYC, SIX2
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| Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis.
|
| Xu J, Wong EY, Cheng C, Li J, Sharkar MT, Xu CY, Chen B, Sun J, Jing D, Xu PX.
|
| Dev Cell 31(4):434-47. doi: 10.1016/j.devcel.2014.10.015. Epub 2014 Nov 24.
2014
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24 | MYC, SIN3B
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| Sin3b interacts with Myc and decreases Myc levels.
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| Garcia-Sanz P, Quintanilla A, Lafita MC, Moreno-Bueno G, García-Gutierrez L, Tabor V, Varela I, Shiio Y, Larsson LG, Portillo F, Leon J.
|
| J Biol Chem 289(32):22221-36. doi: 10.1074/jbc.M113.538744.
2014
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25 | MYC, TFAP4
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| c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells.
|
| Chou C, Pinto AK, Curtis JD, Persaud SP, Cella M, Lin CC, Edelson BT, Allen PM, Colonna M, Pearce EL, Diamond MS, Egawa T.
|
| Nat Immunol 15(9):884-93. doi: 10.1038/ni.2943. Epub 2014 Jul 13.
2014
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26 | ERBB2, HOTAIR, MYC, PTEN, RBM38, WIF1
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| The molecular mechanism of HOTAIR in tumorigenesis, metastasis, and drug resistance.
|
| Zhou X, Chen J, Tang W.
|
| Acta Biochim Biophys Sin (Shanghai) 46(12):1011-5. doi: 10.1093/abbs/gmu104. Epub 2014 Nov 10. Review.
2014
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27 | KAT2A, MYC, TRRAP
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| MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits.
|
| Zhang N, Ichikawa W, Faiola F, Lo SY, Liu X, Martinez E.
|
| Biochim Biophys Acta 1839(5):395-405. doi: 10.1016/j.bbagrm.2014.03.017. Epub 2014 Apr 3.
2014
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28 | MYC, NME2, PIWIL2
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| PIWIL2 induces c-Myc expression by interacting with NME2 and regulates c-Myc-mediated tumor cell proliferation
|
| Yao Y, Li C, Zhou X, Zhang Y, Lu Y, Chen J, Zheng X, Tao D, Liu Y, Ma Y.
|
| Oncotarget. Sep 30;5(18):8466-77. doi: 10.18632/oncotarget.2327 2014
|
29 | MYC, PTEN
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| MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase.
|
| Kaur M, Cole MD.
|
| Cancer Res 73(2):695-705. doi: 10.1158/0008-5472.CAN-12-2522. Epub 2012 Nov 7.
2013
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30 | MYC, RAN
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| RanGTPase: a candidate for Myc-mediated cancer progression.
|
| Yuen HF, Gunasekharan VK, Chan KK, Zhang SD, Platt-Higgins A, Gately K, O'Byrne K, Fennell DA, Johnston PG, Rudland PS, El-Tanani M.
|
| J Natl Cancer Inst 105(7):475-88. doi: 10.1093/jnci/djt028. Epub 2013 Mar 6.
2013
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31 | MYC, STK38
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| STK38 is a critical upstream regulator of MYC's oncogenic activity in human B-cell lymphoma.
|
| Bisikirska BC, Adam SJ, Alvarez MJ, Rajbhandari P, Cox R, Lefebvre C, Wang K, Rieckhof GE, Felsher DW, Califano A.
|
| Oncogene 32(45):5283-91. doi: 10.1038/onc.2012.543. Epub 2012 Nov 26.
2013
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32 | MYC, MYCN, SIRT2
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| The histone deacetylase SIRT2 stabilizes Myc oncoproteins.
|
| Liu PY, Xu N, Malyukova A, Scarlett CJ, Sun YT, Zhang XD, Ling D, Su SP, Nelson C, Chang DK, Koach J, Tee AE, Haber M, Norris MD, Toon C, Rooman I, Xue C, Cheung BB, Kumar S, Marshall GM, Biankin AV, Liu T.
|
| Cell Death Differ 20(3):503-14. doi: 10.1038/cdd.2012.147. Epub 2012 Nov 23.
2013
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33 | ASH2L, CHD7, MYC
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| The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells.
|
| Wan M, Liang J, Xiong Y, Shi F, Zhang Y, Lu W, He Q, Yang D, Chen R, Liu D, Barton M, Songyang Z.
|
| J Biol Chem 288(7):5039-48. doi: 10.1074/jbc.M112.424515. Epub 2012 Dec 13.
2013
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34 | E2F1, MYC, PBK
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| c-Myc and E2F1 drive PBK/TOPK expression in high-grade malignant lymphomas.
|
| Hu F, Gartenhaus RB, Zhao XF, Fang HB, Minkove S, Poss DE, Rapoport AP.
|
| Leuk Res 37(4):447-54. doi: 10.1016/j.leukres.2012.11.010. Epub 2012 Dec 10.
2013
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35 | CYS1, MYC, NDN
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| The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression.
|
| Wu M, Yang C, Tao B, Bu S, Guay-Woodford LM.
|
| PLoS One 8(12):e83062. doi: 10.1371/journal.pone.0083062. eCollection 2013.
2013
|
36 | GPC3, MYC
|
| Oncogenic activation of glypican-3 by c-Myc in human hepatocellular carcinoma.
|
| Li L, Jin R, Zhang X, Lv F, Liu L, Liu D, Liu K, Li N, Chen D.
|
| Hepatology 56(4):1380-90. doi: 10.1002/hep.25891.
2012
|
37 | ELAVL1, MYC, RBM38
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| The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation.
|
| Cho SJ, Jung YS, Zhang J, Chen X.
|
| J Biol Chem 287(18):14535-44. doi: 10.1074/jbc.M111.326827. Epub 2012 Feb 27.
2012
|
38 | DYRK2, JUN, MYC
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| DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells.
|
| Taira N, Mimoto R, Kurata M, Yamaguchi T, Kitagawa M, Miki Y, Yoshida K.
|
| J Clin Invest 122(3):859-72. doi: 10.1172/JCI60818. Epub 2012 Feb 6.
2012
|
39 | MYC, VDR
|
| Vitamin D receptor as a master regulator of the c-MYC/MXD1 network.
|
| Salehi-Tabar R, Nguyen-Yamamoto L, Tavera-Mendoza LE, Quail T, Dimitrov V, An BS, Glass L, Goltzman D, White JH.
|
| Proc Natl Acad Sci U S A 109(46):18827-32. doi: 10.1073/pnas.1210037109. Epub 2012 Oct 29.
2012
|
40 | CDX2, FUT2, MYC
|
| Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition.
|
| Sakuma K, Aoki M, Kannagi R.
|
| Proc Natl Acad Sci U S A 109(20):7776-81. doi: 10.1073/pnas.1111135109. Epub 2012 Apr 30.
2012
|
41 | CIP2A, MYC
|
| CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes.
|
| Niemelä M, Kauko O, Sihto H, Mpindi JP, Nicorici D, Pernilä P, Kallioniemi OP, Joensuu H, Hautaniemi S, Westermarck J.
|
| Oncogene 31(39):4266-78. doi: 10.1038/onc.2011.599.
2012
|
42 | MYC
|
| c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells.
|
| Nie Z, Hu G, Wei G, Cui K, Yamane A, Resch W, Wang R, Green DR, Tessarollo L, Casellas R, Zhao K, Levens D.
|
| Cell 151(1):68-79. doi: 10.1016/j.cell.2012.08.033.
2012
|
43 | KLF1, KLF2, MYC
|
| Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis.
|
| Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M.
|
| Mol Cell Biol 32(13):2628-44. doi: 10.1128/MCB.00104-12. Epub 2012 May 7.
2012
|
44 | KRAS, MYC, NFE2L2
|
| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
|
| DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES, Scrimieri F, Winter JM, Hruban RH, Iacobuzio-Donahue C, Kern SE, Blair IA, Tuveson DA.
|
| Nature 475(7354):106-9. doi: 10.1038/nature10189.
2011
|
45 | MAX, MYC
|
| Sirt1 deacetylates c-Myc and promotes c-Myc/Max association.
|
| Mao B, Zhao G, Lv X, Chen HZ, Xue Z, Yang B, Liu DP, Liang CC.
|
| Int J Biochem Cell Biol 43(11):1573-81. doi: 10.1016/j.biocel.2011.07.006. Epub 2011 Jul 22.
2011
|
46 | MYC, ZBTB17
|
| The role of the transcription factor Miz-1 in lymphocyte development and lymphomagenesis-Binding Myc makes the difference
|
| Möröy T, Saba I, Kosan C.
|
| Semin Immunol. Oct;23(5):379-87. doi: 10.1016/j.smim.2011.09.001. Epub 2011 Oct 13. 2011
|
47 | MYC, RPL11, TRRAP
|
| Ribosomal protein L11 associates with c-Myc at 5 S rRNA and tRNA genes and regulates their expression.
|
| Dai MS, Sun XX, Lu H.
|
| J Biol Chem 285(17):12587-94. Epub 2010 Mar 1.
2010
|
48 | MYC
|
| c-Myc regulates transcriptional pause release.
|
| Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA.
|
| Cell 141(3):432-45.
2010
|
49 | FAM84B, MYC
|
| 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.
|
| Ahmadiyeh N, Pomerantz MM, Grisanzio C, Herman P, Jia L, Almendro V, He HH, Brown M, Liu XS, Davis M, Caswell JL, Beckwith CA, Hills A, Macconaill L, Coetzee GA, Regan MM, Freedman ML.
|
| Proc Natl Acad Sci U S A 107(21):9742-6. Epub 2010 May 7. 2010
|
50 | MAX, MYC, ZBTB17
|
| The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance.
|
| van Riggelen J, Müller J, Otto T, Beuger V, Yetil A, Choi PS, Kosan C, Möröy T, Felsher DW, Eilers M.
|
| Genes Dev 24(12):1281-94.PMID: 20551174 2010
|
51 | FBXW7, IKBKG, MYC
|
| NEMO stabilizes c-Myc through direct interaction in the nucleus.
|
| Kim BY, Yang JS, Kwak SY, Zhang XK, Han YH.
|
| FEBS Lett 584(22):4524-30. Epub 2010 Oct 21.
2010
|
52 | CEBPD, MAX, MYC, ZBTB17
|
| Myc interacts with Max and Miz1 to repress C/EBPdelta promoter activity and gene expression.
|
| Si J, Yu X, Zhang Y, DeWille JW.
|
| Mol Cancer 9:92.
2010
|
53 | AXIN1, MYC
|
| The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc.
|
| Arnold HK, Zhang X, Daniel CJ, Tibbitts D, Escamilla-Powers J, Farrell A, Tokarz S, Morgan C, Sears RC.
|
| EMBO J 28(5):500-12. Epub 2009 Jan 8.
2009
|
54 | MYC
|
| A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition.
|
| Smith AP, Verrecchia A, Fagà G, Doni M, Perna D, Martinato F, Guccione E, Amati B.
|
| Oncogene 28(3):422-30 2009
|
55 | DLX5, MYC
|
| DLX5 (Distal-less Homeobox 5) Promotes Tumor Cell Proliferation by Transcriptionally Regulating MYC.
|
| Xu J, Testa JR.
|
| J Biol Chem 284(31):20593-601. Epub 2009 Jun 4.
2009
|
56 | MYC
|
| Frequent upregulation of MYC in plasma cell leukemia.
|
| Chiecchio L, Dagrada GP, White HE, Towsend MR, Protheroe RK, Cheung KL, Stockley DM, Orchard KH, Cross NC, Harrison CJ, Ross FM; UK Myeloma Forum.
|
| Genes Chromosomes Cancer 48(7):624-36.
2009
|
57 | MYC, NCL
|
| Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein.
|
| González V, Guo K, Hurley L, Sun D.
|
| J Biol Chem 284(35):23622-35. Epub 2009 Jul 6.
2009
|
58 | MAX, MNT, MYC
|
| Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes.
|
| Yang H, Li TW, Ko KS, Xia M, Lu SC.
|
| Hepatology 49(3):860-70.
2009
|
59 | MYC, NSUN2, NUSAP1
|
| The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability.
|
| Hussain S, Benavente SB, Nascimento E, Dragoni I, Kurowski A, Gillich A, Humphreys P, Frye M.
|
| J Cell Biol 186(1):27-40.
2009
|
60 | BZW2, MYC
|
| Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis.
|
| Wu CH, Sahoo D, Arvanitis C, Bradon N, Dill DL, Felsher DW.
|
| PLoS Genet 4(6):e1000090.
2008
|
61 | EP400, MYC
|
| Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc.
|
| Tworkowski KA, Chakraborty AA, Samuelson AV, Seger YR, Narita M, Hannon GJ, Lowe SW, Tansey WP.
|
| Proc Natl Acad Sci U S A 105(16):6103-8. Epub 2008 Apr 14.
2008
|
62 | MYC, TP63, UBCSL
|
| Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.
|
| Kiemeney LA, Thorlacius S, Sulem P, Geller F, Aben KK, Stacey SN, Gudmundsson J, Jakobsdottir M, Bergthorsson JT, Sigurdsson A, Blondal T, Witjes JA, Vermeulen SH, Hulsbergen-van de Kaa CA, Swinkels DW, Ploeg M, Cornel EB, Vergunst H, Thorgeirsson TE, Gudbjartsson D, Gudjonsson SA, Thorleifsson G, Kristinsson KT, Mouy M, Snorradottir S, Placidi D, Campagna M, Arici C, Koppova K, Gurzau E, Rudnai P, Kellen E, Polidoro S, Guarrera S, Sacerdote C, Sanchez M, Saez B, Valdivia G, Ryk C, de Verdier P, Lindblom A, Golka K, Bishop DT, Knowles MA, Nikulasson S, Petursdottir V, Jonsson E, Geirsson G, Kristjansson B, Mayordomo JI, Steineck G, Porru S, Buntinx F, Zeegers MP, Fletcher T, Kumar R, Matullo G, Vineis P, Kiltie AE, Gulcher JR, Thorsteinsdottir U, Kong A, Rafnar T, Stefansson K.
|
| Nat Genet 40(11):1307-12. Epub 2008 Sep 14. 2008
|
63 | MYC, TFAP4
|
| AP4 encodes a c-MYC-inducible repressor of p21.
|
| Jung P, Menssen A, Mayr D, Hermeking H.
|
| Proc Natl Acad Sci U S A 105(39):15046-51. Epub 2008 Sep 25.
2008
|
64 | HSPD1, MYC
|
| Direct regulation of HSP60 expression by c-MYC induces transformation.
|
| Tsai YP, Teng SC, Wu KJ.
|
| FEBS Lett 582(29):4083-8. Epub 2008 Nov 20.
2008
|
65 | MYC
|
| Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency.
|
| Barna M, Pusic A, Zollo O, Costa M, Kondrashov N, Rego E, Rao PH, Ruggero D.
|
| Nature 456(7224):971-5. Epub 2008 Nov 16.
2008
|
66 | FAM84B, MYC
|
| Multiple loci with different cancer specificities within the 8q24 gene desert.
|
| Ghoussaini M, Song H, Koessler T, Al Olama AA, Kote-Jarai Z, Driver KE, Pooley KA, Ramus SJ, Kjaer SK, Hogdall E, DiCioccio RA, Whittemore AS, Gayther SA, Giles GG, Guy M, Edwards SM, Morrison J, Donovan JL, Hamdy FC, Dearnaley DP, Ardern-Jones AT, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Brown PM, Hopper JL, Neal DE, Pharoah PD, Ponder BA, Eeles RA, Easton DF, Dunning AM; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators.
|
| J Natl Cancer Inst 100(13):962-6. Epub 2008 Jun 24.PMID: 18577746 2008
|
67 | MYC
|
| A role for Myc in facilitating transcription activation by E2F1.
|
| Leung JY, Ehmann GL, Giangrande PH, Nevins JR.
|
| Oncogene 27(30):4172-9. Epub 2008 Mar 17.
2008
|
68 | MYC, TAF4B
|
| Expression of the TAF4b gene is induced by MYC through a non-canonical, but not canonical, E-box which contributes to its specific response to MYC.
|
| Teye K, Okamoto K, Tanaka Y, Umata T, Ohnuma M, Moroi M, Kimura H, Tsuneoka M.
|
| Int J Oncol 33(6):1271-80.
2008
|
69 | APC,MYC
|
| Myc deletion rescues Apc deficiency in the small intestine.
|
| Sansom OJ, Meniel VS, Muncan V, Phesse TJ, Wilkins JA, Reed KR, Vass JK, Athineos D, Clevers H, Clarke AR.
|
| Nature 446(7136):676-9. Epub 2007 Mar 21. 2007
|
70 | MYC,NOTCH1
|
| The Notch1/c-Myc pathway in T cell leukemia.
|
| Sharma VM, Draheim KM, Kelliher MA.
|
| Cell Cycle 6(8):927-30. Epub 2007 Apr 11. 2007
|
71 | USP28, FBXW7, MYC
|
| The ubiquitin-specific protease USP28 is required for MYC stability.
|
| Popov N, Wanzel M, Madiredjo M, Zhang D, Beijersbergen R, Bernards R, Moll R, Elledge SJ, Eilers M.
|
| Nat Cell Biol 9(7):765-74. Epub 2007 Jun 10. 2007
|
72 | MYC, TERF1
|
| c-Myc interacts with TRF1/PIN2 and regulates telomere length.
|
| Kim H, Chen J.
|
| Biochem Biophys Res Commun 362(4):842-7. Epub 2007 Aug 22. 2007
|
73 | DKC1, MYC
|
| DKC1 is a direct and conserved transcriptional target of c-MYC.
|
| Alawi F, Lee MN.
|
| Biochem Biophys Res Commun 362(4):893-8. Epub 2007 Aug 24. 2007
|
74 | MYC, PAX5, ZBTB5, ZCCHC7
|
| Mapping of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas.
|
| Bertrand P, Bastard C, Maingonnat C, Jardin F, Maisonneuve C, Courel MN, Ruminy P, Picquenot JM, Tilly H.
|
| Leukemia 21(3):515-23. Epub 2007 Jan 18.
2007
|
75 | MYC, PVT1
|
| Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.
|
| Guan Y, Kuo WL, Stilwell JL, Takano H, Lapuk AV, Fridlyand J, Mao JH, Yu M, Miller MA, Santos JL, Kalloger SE, Carlson JW, Ginzinger DG, Celniker SE, Mills GB, Huntsman DG, Gray JW.
|
| Clin Cancer Res 13(19):5745-55.
2007
|
76 | FAM84B, MYC
|
| Statistical recombinant mapping in extended high-risk Utah pedigrees narrows the 8q24 prostate cancer locus to 2.0 Mb.
|
| Camp NJ, Farnham JM, Allen-Brady K, Cannon-Albright LA.
|
| Prostate 67(13):1456-64.PMID: 17654497 2007
|
77 | BMI1, MYC, PCGF2
|
| Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins.
|
| Guo WJ, Datta S, Band V, Dimri GP.
|
| Mol Biol Cell 18(2):536-46. Epub 2006 Dec 6.
2007
|
78 | ATM, TP53, MYC
|
| ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.
|
| Pusapati RV, Rounbehler RJ, Hong S, Powers JT, Yan M, Kiguchi K, McArthur MJ, Wong PK, Johnson DG.
|
| Proc Natl Acad Sci U S A 103(5):1446-51. Epub 2006 Jan 23. 2006
|
79 | REST, MYC
|
| Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation.
|
| Su X, Gopalakrishnan V, Stearns D, Aldape K, Lang FF, Fuller G, Snyder E, Eberhart CG, Majumder S.
|
| Mol Cell Biol 26(5):1666-78. 2006
|
80 | PARP10, MYC
|
| PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.
|
| Yu M, Schreek S, Cerni C, Schamberger C, Lesniewicz K, Poreba E, Vervoorts J, Walsemann G, Grotzinger J, Kremmer E, Mehraein Y, Mertsching J, Kraft R, Austen M, Luscher-Firzlaff J, Luscher B.
|
| Oncogene 24(12):1982-93. 2005
|
81 | MTA1, MYC
|
| Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein.
|
| Zhang XY, DeSalle LM, Patel JH, Capobianco AJ, Yu D, Thomas-Tikhonenko A, McMahon SB.
|
| Proc Natl Acad Sci U S A 102(39):13968-73. Epub 2005 Sep 19. 2005
|
82 | MYC, GTF2H4
|
| TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression.
|
| Weber A, Liu J, Collins I, Levens D.
|
| Mol Cell Biol 25(1):147-61. 2005
|
83 | MYC
|
| c-Myc-regulated microRNAs modulate E2F1 expression
|
| O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT.
|
| Nature 435(7043):839-43 2005
|
84 | MYC
|
| Myc represses transcription through recruitment of DNA methyltransferase corepressor
|
| Brenner C, Deplus R, Didelot C, Loriot A, Viré E, De Smet C, Gutierrez A, Danovi D, Bernard D, Boon T, Pelicci PG, Amati B, Kouzarides T, de Launoit Y, Di Croce L, Fuks F.
|
| EMBO J. 24(2):336-46 2005
|
85 | MYC
|
| PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts
|
| Cairo S, De Falco F, Pizzo M, Salomoni P, Pandolfi PP, Meroni G.
|
| Oncogene 4(13):2195-203 2005
|
86 | MYC
|
| MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer.
|
| Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, Bachmann MH, Borowsky AD, Ruebner B, Cardiff RD, Yang Q, Bishop JM, Contag CH, Felsher DW.
|
| Nature 431(7012):1112-7. Epub 2004 Oct 10. 2004
|
87 | EIF3H,MYC,TRPS1
|
| Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer.
|
| Savinainen KJ, Linja MJ, Saramaki OR, Tammela TL, Chang GT, Brinkmann AO, Visakorpi T.
|
| Br J Cancer 90(5):1041-6. 2004
|
88 | MYC
|
| Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation
|
| Jin Z, Gao F, Flagg T, Deng X
|
| J Biol Chem. 279(38):40209-19 2004
|
89 | MYC
|
| The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis
|
| Ruggero D, Montanaro L, Ma L, Xu W, Londei P, Cordon-Cardo C, Pandolfi PP.
|
| Nat Med. 10(5):484-6 2004
|
90 | MYC
|
| MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
|
| Shachaf, C. M.; Kopelman, A. M.; Arvanitis, C.; Karlsson, A.; Beer, S.; Mandy, S.; Bachmann, M. H.; Borowsky, A. D.; Ruebner, B.; Cardiff, R. D.; Yang, Q.; Bishop, J. M.; Contag, C. H.; Felsher, D. W.
|
| Nature 431: 1112-1117 2004
|
91 | MYC, VHL
|
| The allelic loss of chromosome 3p25 with c-myc gain is related to the development of clear-cell renal cell carcinoma.
|
| Yamaguchi S, Yoshihiro S, Matsuyama H, Nagao K, Fukunaga K, Matsumoto H, Matsuda K, Oba K, Naito K.
|
| Clin Genet 63(3):184-91. 2003
|
92 | CTNND2, CTTN, MYC
|
| Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho
|
| Martinez MC, Ochiishi T, Majewski M, Kosik KS.
|
| J Cell Biol. 162(1):99-111 2003
|
93 | MYC
|
| MYC recruits the TIP60 histone acetyltransferase complex to chromatin
|
| Frank SR, Parisi T, Taubert S, Fernandez P, Fuchs M, Chan HM, Livingston DM, Amati B
|
| EMBO Rep. 4(6):575-80 2003
|
94 | MYC
|
| Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX
|
| Mac Partlin M, Homer E, Robinson H, McCormick CJ, Crouch DH, Durant ST, Matheson EC, Hall AG, Gillespie DA, Brown R.
|
| Oncogene 22(6):819-25 2003
|
95 | MYC
|
| Guanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and interferes with c-Myc-mediated apoptosis in rat-1 fibroblasts
|
| Otsuki Y, Tanaka M, Kamo T, Kitanaka C, Kuchino Y, Sugimura H
|
| J Biol Chem. 278(7):5132-40 2003
|
96 | MYC
|
| Myc-induced T cell leukemia in transgenic zebrafish
|
| Langenau, D. M.; Traver, D.; Ferrando, A. A.; Kutok, J. L.; Aster, J. C.; Kanki, J. P.; Lin, S.; Prochownik, E.; Trede, N. S.; Zon, L. I.; Look, A. T.
|
| Science. 299: 887-890 2003
|
97 | BCL2, CDKN2A, MYC, RB1, TSG3B
|
| Cytogenetics and molecular genetics of lung cancer.
|
| Mitsuuchi Y, Testa JR.
|
| Am J Med Genet 115(3):183-8. 2002
|
98 | MYC
|
| BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation
|
| Park J, Wood MA, Cole MD.
|
| Mol Cell Biol. 22(5):1307-16 2002
|
99 | MYC
|
| A novel myc target gene, mina53, that is involved in cell proliferation
|
| mina53 (Myc-induced nuclear antigen with a molecular mass of 53 kDa)
|
| J Biol Chem. 277(38):35450-9 2002
|
100 | MYC
|
| A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer
|
| Li H, Lee TH, Avraham H.
|
| J Biol Chem. 277(23):20965-73 2002
|
101 | MYC
|
| A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc
|
| Chapman NR, Webster GA, Gillespie PJ, Wilson BJ, Crouch DH, Perkins ND.
|
| Biochem J. 366(Pt 2):459-69 2002
|
102 | MYC
|
| Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)
|
| Feng XH, Liang YY, Liang M, Zhai W, Lin X.
|
| Mol Cell. 9(1):133-43 2002
|
103 | MYC
|
| p73 Interacts with c-Myc to regulate Y-box-binding protein-1 expression
|
| Uramoto H, Izumi H, Ise T, Tada M, Uchiumi T, Kuwano M, Yasumoto K, Funa K, Kohno K
|
| J Biol Chem. 277(35):31694-702 2002
|
104 | MYC
|
| cMyc is essential for vasculogenesis and angiogenesis during development and tumor progress
|
| Baudino, T. A.; McKay, C.; Pendeville-Samain, H.; Nilsson, J. A.; Maclean, K. H.; White, E. L.; Davis, A. C.; Ihle, J. N.; Cleveland, J. L.
|
| Genes Dev. 16: 2530-2543 2002
|
105 | MYC
|
| Sustained loss of a neoplastic phenotype by brief inactivation of MYC
|
| Jain, M.; Arvanitis, C.; Chu, K.; Dewey, W.; Leonhardt, E.; Trinh, M.; Sundberg, C. D.; Bishop, J. M.; Felsher, D. W.
|
| Science. 297: 102-104 2002
|
106 | MYC
|
| Role of 14-3-3epsilon, c-Myc/Max, and Akt phosphorylation in HIV-1 gp 120-induced mesangial cell proliferation.
|
| Kapasi AA, Fan S, Singhal PC.
|
| Am J Physiol Renal Physiol. 280(2):F333-42 2001
|
107 | MYC
|
| Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor
|
| Izumi H, Molander C, Penn LZ, Ishisaki A, Kohno K, Funa K.
|
| J Cell Sci. 114(Pt 8):1533-44 2001
|
108 | MYC
|
| Repression of p15INK4b expression by Myc through association with Miz-1
|
| Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M.
|
| Nat Cell Biol. 3(4):392-9 2001
|
109 | CDK4, MYC
|
| Identification of CDK4 as a target of c-MYC.
|
| Hermeking H, Rago C, Schuhmacher M, Li Q, Barrett JF, Obaya AJ, O'Connell BC, Mateyak MK, Tam W, Kohlhuber F, Dang CV, Sedivy JM, Eick D, Vogelstein B, Kinzler KW.
|
| Proc Natl Acad Sci U S A 97(5):2229-34. 2000
|
110 | MYC
|
| CDC6 interacts with c-Myc to inhibit E-box-dependent transcription by abrogating c-Myc/Max complex
|
| Takayama M, Taira T, Iguchi-Ariga SM, Ariga H.
|
| FEBS Lett. 477(1-2):43-8 2000
|
111 | ALB, CAD, CCNA2, CDC25A, CDK1, CEBPA, COL1A1, COL1A2, COL3A1, COL6A3, DHFR, DMTF1, GADD45A, JUN, LDHA, MXI1, MYC, ODC1, RCC1, SERPINE1, TERT, TK1, TK2, TP53
|
| c-Myc target genes involved in cell growth, apoptosis, and metabolism.
|
| Dang CV.
|
| Mol Cell Biol 19(1):1-11. Review. No abstract available 1999
|
112 | MYC
|
| c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function.
|
| Cheng SW, et al.
|
| Nat Genet 22(1):102-5. 1999
|
113 | BCL2, BCL6, MYC
|
| Concurrent chromosomal alterations at 3q27, 8q24 and 18q21 in B-cell lymphomas.
|
| Au WY, et al.
|
| Br J Haematol 105(2):437-40. 1999
|
114 | MYC
|
| Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase
|
| Noguchi K, Kitanaka C, Yamana H, Kokubu A, Mochizuki T, Kuchino Y.
|
| J Biol Chem. 274(46):32580-7 1999
|
115 | MYC
|
| Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y
|
| Taira T, Sawai M, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H.
|
| J Biol Chem. 274(34):24270-9 1999
|
116 | MYC
|
| c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function
|
| Cheng SW, Davies KP, Yung E, Beltran RJ, Yu J, Kalpana GV
|
| N Nat Genet. 1999
|
117 | BCL2, BCL8, BRINP1, CDK4, GLI1, MDM2, MYC, REL
|
| Chromosomal and gene amplification in diffuse large B-cell lymphoma.
|
| Rao PH, et al.
|
| Blood 92 : 234-240. 1998
|
118 | MYC
|
| The proto-oncogene c-myc and apoptosis.
|
| Hoffman B, et al.
|
| Oncogene 17(25):3351-7. Review. 1998
|
119 | MYC
|
| AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC
|
| Taira T, Maëda J, Onishi T, Kitaura H, Yoshida S, Kato H, Ikeda M, Tamai K, Iguchi-Ariga SM, Ariga H.
|
| Genes Cells. 3(8):549-65 1998
|
120 | MYC
|
| Identification of a large Myc-binding protein that contains RCC1-like repeats.
|
| Guo Q, Xie J, Dang CV, Liu ET, Bishop JM.
|
| Proc Natl Acad Sci U S A. 95(16):9172-7 1998
|
121 | BRCA1, MYC
|
| BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells.
|
| Wang Q, Zhang H, Kajino K, Greene MI.
|
| Oncogene. 17(15):1939-48 1998
|
122 | MYC
|
| MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc
|
| Mori K, Maeda Y, Kitaura H, Taira T, Iguchi-Ariga SM, Ariga H
|
| J Biol Chem. 273(45):29794-800 1998
|
123 | MYC
|
| c-Raf kinase binds to N-terminal domain of c-Myc
|
| Alexandrov I, Shlyakhova L, Vartanian A, Zajac-Kaye M, Alexandrova N.
|
| FEBS Lett. 414(2):465-70 1997
|
124 | MYC
|
| An alternative pathway for gene regulation by Myc
|
| Peukert K, Staller P, Schneider A, Carmichael G, Hänel F, Eilers M.
|
| EMBO J. 16(18):5672-86 1997
|
125 | MYC
|
| Functional interaction of the c-Myc transactivation domain with the TATA binding protein: evidence for an induced fit model of transactivation domain folding
|
| McEwan IJ, Dahlman-Wright K, Ford J, Wright AP.
|
| Biochemistry. 35(29):9584-93 1996
|
126 | MYC
|
| Isolation and characterization of Nmi, a novel partner of Myc proteins.
|
| Bao J, Zervos AS.
|
| Oncogene 12(10):2171-6 1996
|
127 | MYC
|
| Transcriptional activation by Myc is under negative control by the transcription factor AP-2
|
| Gaubatz S, Imhof A, Dosch R, Werner O, Mitchell P, Buettner R, Eilers M
|
| EMBO J. 14(7):1508-19 1995
|
128 | MYC
|
| The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro
|
| Alexandrova N, Niklinski J, Bliskovsky V, Otterson GA, Blake M, Kaye FJ, Zajac-Kaye M.
|
| Mol Cell Biol. 15(9):5188-95 1995
|
129 | MYC, TUBA1A
|
| The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro.
|
| Alexandrova N, Niklinski J, Bliskovsky V, Otterson GA, Blake M, Kaye FJ, Zajac-Kaye M.
|
| Mol Cell Biol 15(9):5188-95.PMID: 7651436 1995
|
130 | MYC, PVT1
|
| Breakpoints of Burkitt's lymphoma t(8;22) translocations map within a distance of 300 kb downstream of MYC.
|
| Zeidler R, et al.
|
| Genes Chromosomes Cancer 9 : 282-287. 1994
|
131 | MYC
|
| MAP kinase binds to the NH2-terminal activation domain of c-Myc
|
| Gupta S, Davis RJ.
|
| FEBS Lett. 353(3):281-5 1994
|
132 | MYC
|
| Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation
|
| Beijersbergen RL, Hijmans EM, Zhu L, Bernards R.
|
| EMBO J. 13(17):4080-6 1994
|
133 | MYC
|
| Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma.
|
| Yano T, et al.
|
| Oncogene 8 : 2741-2748. 1993
|
134 | MYC
|
| Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc
|
| Shrivastava A, Saleque S, Kalpana GV, Artandi S, Goff SP, Calame K.
|
| Science. 262(5141):1889-92 1993
|
135 | MYC
|
| c-myc is an erythropoietin early response gene in normal erythroid cells:evidence for a protein kinase C-mediated signal.
|
| Spangler R, et al.
|
| Blood 79 : 52-57. 1992
|
136 | MYC
|
| Dinucleotide repeat polymorphism at the human c-myc oncogene locus (MYC).
|
| Polymeropoulos MH, et al.
|
| Hum Mol Genet 1 : 65. 1992
|
137 | MYC, FOS, TP53
|
| Co-ordinate expression of c-fos, p53 and cytokeratin genes during the alteration of growth of human hepatoma cells; mRNA levels measured by reverse transcription and polymerase chain reaction.
|
| Kaneko Y, et al.
|
| Cancer Lett 66 : 155-164. 1992
|
138 | MYC
|
| Immunohistochemistry, in situ hybridization and polymerase chain reaction (PCR) in detecting c-myc expression in human malignancies.
|
| Tervahauta AI, et al.
|
| Anticancer Res 12 : 1005-1012. 1992
|
139 | MYC
|
| Transcription of human c-myc in permeabilized nuclei is associated with formation of Z-DNA in three discrete regions of the gene.
|
| Wittig B, et al.
|
| EMBO J 11 : 4653-4663. 1992
|
140 | MAX, MYC
|
| Alternative forms of Max as enhancers or suppressors of Myc-ras cotransformation.
|
| Makela TP, Koskinen PJ, Vastrik I, Alitalo K.
|
| Science 256(5055):373-7. 1992
|
141 | MYC
|
| Mapping of the MYC gene to band 8q24.12-q24.13 by R-banding and distal to fra(8)(q24.11), FRA8E, by fluorescence in situ hybridization.
|
| Takahashi E, et al.
|
| Cytogenet Cell Genet 57 : 109-111. 1991
|
142 | MYC
|
| Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
|
| Blackwood EM, Eisenman RN.
|
| Science. 251(4998):1211-7 1991
|
143 | MYC
|
| A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression.
|
| Seth A, Alvarez E, Gupta S, Davis RJ
|
| J Biol Chem. 266(35):23521-4 1991
|
144 | MYC, TCL4
|
| A 3' truncation of MYC caused by chromosomal translocation in a human T-cell leukemia increases mRNA stability.
|
| Aghib DF, Bishop JM, Ottolenghi S, Guerrasio A, Serra A, Saglio G.
|
| Oncogene 5(5):707-11. 1990
|
145 | MYC, TCL4
|
| Chromosomal translocation in T-cell leukemia line HUT 78 results in a MYC fusion transcript.
|
| Finger LR, et al.
|
| Proc Natl Acad Sci U S A 85 : 9158-9162. 1988
|
146 | MYC
|
| A 0.5 kb insert polymorphism 3'to the c-myc gene.
|
| Middleton PG, et al.
|
| Nucleic Acids Res 16 : 3123. 1988
|
147 | MYC, PVT1
|
| A human chromosome 8 region with abnormalities in B cell, HTLV-I+ T cell and c-myc amplified tumours.
|
| Mengle-Gaw L, et al.
|
| EMBO J 6 : 1959-1965. 1987
|
148 | MYC
|
| p380-8A 1.8 SaSs, a single copy clone 5' of c-myc at 8q24 which recognizes an SstI polymorphism.
|
| Haluska FG, et al.
|
| Nucleic Acids Res 15 : 865. 1987
|
149 | TRA@, MYC
|
| Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias.
|
| Erikson J, Finger L, Sun L, ar-Rushdi A, Nishikura K, Minowada J, Finan J, Emanuel BS, Nowell PC, Croce CM.
|
| Science 232 : 884-886. 1986
|
150 | MYC
|
| Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3'side of MYC.
|
| McKeithan TW, et al.
|
| Proc Natl Acad Sci U S A 83 : 6636-6640. 1986
|
151 | MYC
|
| Analysis of the 3' flanking region of the human c-myc gene in lymphomas with the t(8;22) and t(2;8) chromosome translocations.
|
| Sun LK, et al.
|
| Nucleic Acids Res 14 : 4037-4050. 1986
|
152 | MYC
|
| Mapping by chromosome sorting of several gene probes, including c-myc, to the derivative chromosomes of a 3;8 translocation associated with familial renal cancer.
|
| Harris P, et al.
|
| Cytometry 7 : 589-594. 1986
|
153 | MYC
|
| Cloning and sequence of a c-myc oncogene in a Burkitt's lymphoma cell line that is translocated to a germ line alpha switch region.
|
| Showe LC, et al.
|
| Mol Cell Biol 5 : 501-509. 1985
|
154 | MYC
|
| Translocation of c-myc in the hereditary renal cell carcinoma associated with a t(3;8)(p14.2;q24.13) chromosomal translocation.
|
| Drabkin HA, et al.
|
| Proc Natl Acad Sci U S A 82 : 6980-6984. 1985
|
155 | TG, MYC
|
| Proximity of thyroglobulin and c-myc genes on human chromosome 8.
|
| Rabin M, et al.
|
| Somat Cell Mol Genet 11 : 397-402. 1985
|
156 | EGFR, KRAS1P, MOS, MYB, MYC
|
| Human proto-oncogene assignments.
|
| Sakaguchi AY, et al.
|
| (HGM7) Cytogenet Cell Genet 37 : 572-573. 1984
|
157 | MYC
|
| Nuclear localization and DNA binding properties of a protein expressed by human c-myc oncogene
|
| Persson H, Leder P.
|
| Science. 225(4663):718-21 1984
|
158 | MYC
|
| The human c-myc oncogene : structural consequences of translocation into the IgH locus in Burkitt lymphoma.
|
| Battey J, et al.
|
| Cell 34 : 779-787. 1983
|
159 | MYC, MOS
|
| Two human c-onc genes are located on the long arm of chromosome 8.
|
| Neel BG, et al.
|
| Proc Natl Acad Sci U S A 79 : 7842-7846. 1982
|
160 | MYC
|
| Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.
|
| Taub R, et al.
|
| Proc Natl Acad Sci U S A 79 : 7837-7841. 1982
|
161 | MYC
|
| Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.
|
| Dalla-Favera R, et al.
|
| Proc Natl Acad Sci U S A 79 : 7824-7827. 1982
|