Citations for
1MAZ, MYB, RB1
MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter.
Álvaro-Blanco J, Urso K, Chiodo Y, Martín-Cortázar C, Kourani O, Arco PG, Rodríguez-Martínez M, Calonge E, Alcamí J, Redondo JM, Iglesias T, Campanero MR.
Nucleic Acids Res 45(17):9960-9975. doi: 10.1093/nar/gkx641. 2017
2EP300, HIPK1, MYB, TGFB1I1
The adaptor protein ARA55 and the nuclear kinase HIPK1 assist c-Myb in recruiting p300 to chromatin.
Bengtsen M, Sørensen L, Aabel L, Ledsaak M, Matre V, Gabrielsen OS.
Biochim Biophys Acta 1860(7):751-760. doi: 10.1016/j.bbagrm.2017.05.001. Epub 2017 May 8. 2017
3MYB, SETBP1
Myb expression is critical for myeloid leukemia development induced by Setbp1 activation.
Nguyen N, Vishwakarma BA, Oakley K, Han Y, Przychodzen B, Maciejewski JP, Du Y.
Oncotarget ncotarget. 2016 Nov 16. doi: 10.18632/oncotarget.13383. [Epub ahead of print] 2016
4MYB, PIAS1
PIAS1 binds p300 and behaves as a coactivator or corepressor of the transcription factor c-Myb dependent on SUMO-status.
Ledsaak M, Bengtsen M, Molværsmyr AK, Fuglerud BM, Matre V, Eskeland R, Gabrielsen OS.
Biochim Biophys Acta 1859(5):705-18. doi: 10.1016/j.bbagrm.2016.03.011. 2016
5MYB
MYB is a novel regulator of pancreatic tumour growth and metastasis.
Srivastava SK, Bhardwaj A, Arora S, Singh S, Azim S, Tyagi N, Carter JE, Wang B, Singh AP.
Br J Cancer 113(12):1694-703. doi: 10.1038/bjc.2015.400. 2015
6MYB
c-Myb Binding Sites in Haematopoietic Chromatin Landscapes.
Bengtsen M, Klepper K, Gundersen S, Cuervo I, Drabløs F, Hovig E, Sandve GK, Gabrielsen OS, Eskeland R.
PLoS One 10(7):e0133280. doi: 10.1371/journal.pone.0133280. 2015
7MYB
Role of c-Myb in chondrogenesis.
Oralová V, Matalová E, Janečková E, Drobná Krejčí E, Knopfová L, Šnajdr P, Tucker AS, Veselá I, Šmarda J, Buchtová M.
Bone 76:97-106. doi: 10.1016/j.bone.2015.02.031. 2015
8MYB
Myb via TGFβ is required for collagen type 1 production and skin integrity.
Sampurno S, Cross R, Pearson H, Kaur P, Malaterre J, Ramsay RG.
Growth Factors 33(2):102-12. doi: 10.3109/08977194.2015.1016222. 2015
9MYB
Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes.
Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M.
Stem Cells 33(2):479-90. doi: 10.1002/stem.1855. 2015
10MYB
Myb permits multilineage airway epithelial cell differentiation.
Pan JH, Adair-Kirk TL, Patel AC, Huang T, Yozamp NS, Xu J, Reddy EP, Byers DE, Pierce RA, Holtzman MJ, Brody SL.
Stem Cells 32(12):3245-56. doi: 10.1002/stem.1814. 2014
11BCL11A, DNMT1, MYB
Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
Roosjen M, McColl B, Kao B, Gearing LJ, Blewitt ME, Vadolas J.
FASEB J 28(4):1610-20. doi: 10.1096/fj.13-242669. 2014
12MYB, PAX7
Pax7 is regulated by cMyb during early neural crest development through a novel enhancer.
Vadasz S, Marquez J, Tulloch M, Shylo NA, García-Castro MI.
Development 140(17):3691-702. doi: 10.1242/dev.088328. 2013
13EP300, MYB, cREBBP
Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
Kasper LH, Fukuyama T, Lerach S, Chang Y, Xu W, Wu S, Boyd KL, Brindle PK.
PLoS One 8(12):e82684. doi: 10.1371/journal.pone.0082684. 2013
14MYB
c-Myb inhibits myoblast fusion.
Kaspar P, Ilencikova K, Zikova M, Horvath O, Cermak V, Bartunek P, Strnad H.
PLoS One 8(10):e76742. doi: 10.1371/journal.pone.0076742. 2013
15FOXJ1, MYB
Myb promotes centriole amplification and later steps of the multiciliogenesis program.
Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA.
Development 140(20):4277-86. doi: 10.1242/dev.094102. 2013
16MYB
Myb and the regulation of stem cells in the intestine and brain: a tale of two niches.
Malaterre J, Pereira L, Ramsay RG.
Adv Exp Med Biol 786:353-68. doi: 10.1007/978-94-007-6621-1_19. 2013
17CREBBP, MYB
Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.
Giri R, Morrone A, Toto A, Brunori M, Gianni S.
Proc Natl Acad Sci U S A 110(37):14942-7. doi: 10.1073/pnas.1307337110. 2013
18FBXW5, MYB
Fbxw5 suppresses nuclear c-Myb activity via DDB1-Cul4-Rbx1 ligase-mediated sumoylation.
Kanei-Ishii C, Nomura T, Egoh A, Ishii S.
Biochem Biophys Res Commun 426(1):59-64. doi: 10.1016/j.bbrc.2012.08.032. 2012
19MYB
Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development.
Lungova V, Buchtova M, Janeckova E, Tucker AS, Knopfova L, Smarda J, Matalova E.
Eur J Oral Sci 120(6):495-504. doi: 10.1111/j.1600-0722.2012.01004.x. 2012
20ERBIN, MYB
c-Myb regulates cell cycle-dependent expression of Erbin: an implication for a novel function of Erbin.
Liu D, Shi M, Zhang H, Qian L, Yu M, Hu M, Zhang R, Wang T, Han C, Duan H, Guo N.
PLoS One 7(8):e42903. doi: 10.1371/journal.pone.0042903. 2012
21MYB, NFIB
Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms.
Brill LB 2nd, Kanner WA, Fehr A, Andrén Y, Moskaluk CA, Löning T, Stenman G, Frierson HF Jr.
Mod Pathol od Pathol. 2011 May 13. [Epub ahead of print] 2011
22HBS1L, MYB
A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression.
Farrell JJ, Sherva RM, Chen ZY, Luo HY, Chu BF, Ha SY, Li CK, Lee AC, Li RC, Li CK, Yuen HL, So JC, Ma ES, Chan LC, Chan V, Sebastiani P, Farrer LA, Baldwin CT, Steinberg MH, Chui DH.
Blood 117(18):4935-45. Epub 2011 Mar 8. 2011
23GATA1, MYB
Identification of a transforming MYB-GATA1 fusion gene in acute basophilic leukemia: a new entity in male infants.
Quelen C, Lippert E, Struski S, Demur C, Soler G, Prade N, Delabesse E, Broccardo C, Dastugue N, Mahon FX, Brousset P.
Blood 117(21):5719-22. Epub 2011 Apr 7. 2011
24MYB
MYB is essential for mammary tumorigenesis.
Miao RY, Drabsch Y, Cross RS, Cheasley D, Carpinteri S, Pereira L, Malaterre J, Gonda TJ, Anderson RL, Ramsay RG.
Cancer Res 71(22):7029-37. doi: 10.1158/0008-5472.CAN-11-1015. Epub 2011 Sep 26. 2011
25CASP8AP2, MYB, PIAS1
PIAS1 interacts with FLASH and enhances its co-activation of c-Myb.
Alm-Kristiansen AH, Lorenzo PI, Molværsmyr AK, Matre V, Ledsaak M, Sæther T, Gabrielsen OS.
Mol Cancer 10:21. doi: 10.1186/1476-4598-10-21. 2011
26DHRS2, MDM2, MYB, TP53
Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.
Deisenroth C, Thorner AR, Enomoto T, Perou CM, Zhang Y.
Mol Cell Biol 30(16):3981-93. Epub 2010 Jun 14.PMID: 20547751 2010
27MYB, SNAI2
Expression of Slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin.
Tanno B, Sesti F, Cesi V, Bossi G, Ferrari-Amorotti G, Bussolari R, Tirindelli D, Calabretta B, Raschellà G.
J Biol Chem 285(38):29434-45. Epub 2010 Jul 11. 2010
28HIPK1, MYB
HIPK1 interacts with c-Myb and modulates its activity through phosphorylation.
Matre V, Nordgård O, Alm-Kristiansen AH, Ledsaak M, Gabrielsen OS.
Biochem Biophys Res Commun 388(1):150-4. Epub 2009 Jul 30. 2009
29BTHAL, HBS1L, MYB, SICA
Discovering the genetics underlying foetal haemoglobin production in adults.
Thein SL, Menzel S.
Br J Haematol 145(4):455-67. Epub 2008 Mar 2. Review.PMID: 19344402 2009
30HBS1L, MYB
Control of fetal hemoglobin: new insights emerging from genomics and clinical implications.
Thein SL, Menzel S, Lathrop M, Garner C.
Hum Mol Genet 18(R2):R216-23. Review.PMID: 19808799 2009
31HBS1L, MYB
The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells.
Wahlberg K, Jiang J, Rooks H, Jawaid K, Matsuda F, Yamaguchi M, Lathrop M, Thein SL, Best S.
Blood 114(6):1254-62. Epub 2009 Jun 15.PMID: 19528534 2009
32MYB, NFIB
Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck.
Persson M, Andrén Y, Mark J, Horlings HM, Persson F, Stenman G.
Proc Natl Acad Sci U S A 106(44):18740-4. Epub 2009 Oct 19. 2009
33FBXW7, MYB, NLK
Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation.
Kanei-Ishii C, Nomura T, Takagi T, Watanabe N, Nakayama KI, Ishii S.
J Biol Chem 283(45):30540-8. Epub 2008 Sep 2. 2008
34CASP8AP2, MYB, POLR2A
FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci.
Alm-Kristiansen AH, Saether T, Matre V, Gilfillan S, Dahle O, Gabrielsen OS.
Oncogene 27(34):4644-56. Epub 2008 Apr 14. 2008
35HBS1L, MYB
The HBS1L-MYB intergenic region on chromosome 6q23 is a quantitative trait locus controlling fetal haemoglobin level in carriers of beta-thalassaemia.
So CC, Song YQ, Tsang ST, Tang LF, Chan AY, Ma ES, Chan LC.
J Med Genet 45(11):745-51. Epub 2008 Aug 12.PMID: 18697826 2008
36HBS1L,MYB
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.
Thein SL, Menzel S, Peng X, Best S, Jiang J, Close J, Silver N, Gerovasilli A, Ping C, Yamaguchi M, Wahlberg K, Ulug P, Spector TD, Garner C, Matsuda F, Farrall M, Lathrop M.
Proc Natl Acad Sci U S A 104(27):11346-51. Epub 2007 Jun 25. 2007
37MYB
Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells.
Drabsch Y, Hugo H, Zhang R, Dowhan DH, Miao YR, Gewirtz AM, Barry SC, Ramsay RG, Gonda TJ.
Proc Natl Acad Sci U S A 104(34):13762-7. Epub 2007 Aug 9. 2007
38HBS1L, MYB
The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans.
Menzel S, Jiang J, Silver N, Gallagher J, Cunningham J, Surdulescu G, Lathrop M, Farrall M, Spector TD, Thein SL.
Blood 110(10):3624-6. Epub 2007 Aug 21.PMID: 17712044 2007
39MYB, TRAF
TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation.
Morita Y, Kanei-Ishii C, Nomura T, Ishii S.
Mol Biol Cell 16(11):5433-44. Epub 2005 Sep 14.PMID: 16162816 2005
40MAF, MYB
c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation.
Hedge SP, Kumar A, Kurschner C, Shapiro LH.
Mol Cell Biol 18(5):2729-37. 1998
41MYB
The Myb oncogene product induces DNA-bending.
Saikumar P, et al.
Oncogene 9 : 1279-1287. 1994
42D6S132, D6S133, D6S148, D6S150, D6S170, D6S2, D6S201, D6S21, D6S22, D6S25, D6S32, D6S33, D6S37, D6S39, D6S43, D6S44, D6S48, D6S6, D6S85, MYB
Subregional localization of 20 single-copy loci to chromosome 6 by fluorescence in situ hybridization.
Rao PH, et al.
Genomics 16 : 426-430. 1993
43MYB
Acute- and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides.
Ratajczak MZ, et al.
Blood 79 : 1956-1961. 1992
44ARG1, D6S33, MYB
Genetic linkage group (ARG1-D6S33-MYB) on chromosome 6q containing the arginase-1 and MYB genes.
Nguyen J, et al.
Cytogenet Cell Genet 54 : 95-96. 1990
45MYB
Alternative splicing of the human c-myb gene.
Westin EH, Gorse KM, Clarke MF.
Oncogene 5(8):1117-24. 1990
46MYB
Molecular mapping of the oncogene MYB and rearrangements in malignant melanoma.
Meese E, et al.
Genes Chromosomes Cancer 1 : 88-94. 1989
47MYB
Sublocalization of c-myb to 6q21-q23 by in situ hybridization and c-myb expression in a human teratocarcinoma with 6q rearrangements.
Janssen JW, Vernole P, de Boer PA, Oosterhuis JW, Collard JG.
Cytogenet Cell Genet 41 : 129-135. 1986
48MYB
EcoRI RFLP linked to the human myb gene.
Dozier C, et al.
Nucleic Acids Res 14 : 1928. 1986
49MYB, NRAS
Chromosomal localization of N-ras, K-ras-1, K-ras-2, and myb oncogenes in human cells.
McBride OW, et al.
(HGM7) Cytogenet Cell Genet 37 : 534-535. 1984
50EGFR, KRAS1P, MOS, MYB, MYC
Human proto-oncogene assignments.
Sakaguchi AY, et al.
(HGM7) Cytogenet Cell Genet 37 : 572-573. 1984
51MYB
Regional assignment of human protooncogene c-myb to 6q21->qter.
Zabel BU, et al.
Somat Cell Mol Genet 10 : 105-108. 1984
52FES, MYB
Chromosomal sublocalization of human c-myb and c-fes cellular onc genes.
Harper ME, et al.
Nature 304 : 169-171. 1983
53FES, MYB
Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis onc genes.
Dalla-Favera R, et al.
Proc Natl Acad Sci U S A 79 : 4714-4717. 1982