| 1 | HBS1L, MYB
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| Fetal hemoglobin modulates neurocognitive performance in sickle cell anemia✰,✰✰
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| Heitzer AM, Longoria J, Rampersaud E, Rashkin SR, Estepp JH, Okhomina VI, Wang WC, Raches D, Potter B, Steinberg MH, King AA, Kang G, Hankins JS.
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| Curr Res Transl Med Jul;70(3):103335. doi: 10.1016/j.retram.2022.103335. Epub 2022 Mar 15. 2022
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| 2 | ATF4, HBS1L, MYB
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| ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin.
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| Boontanrart MY, Schröder MS, Stehli GM, Banović M, Wyman SK, Lew RJ, Bordi M, Gowen BG, DeWitt MA, Corn JE.
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| Cell Rep. Aug 4;32(5):107993. doi: 10.1016/j.celrep.2020.107993 2020
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| 3 | MYB, RUVBL2
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| The AAA+ATPase RUVBL2 is essential for the oncogenic function of c-MYB in acute myeloid leukemia.
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| Armenteros-Monterroso E, Zhao L, Gasparoli L, Brooks T, Pearce K, Mansour MR, Martens JHA, de Boer J, Williams O.
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| Leukemia. Dec;33(12):2817-2829. doi: 10.1038/s41375-019-0495-8. Epub 2019 May 28. 2019
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| 4 | HBS1L, MYB
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| A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression.
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| Morrison TA, Wilcox I, Luo HY, Farrell JJ, Kurita R, Nakamura Y, Murphy GJ, Cui S, Steinberg MH, Chui DHK.
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| Blood Cells Mol Dis. Mar;69:1-9. doi: 10.1016/j.bcmd.2017.11.003. Epub 2017 Nov 29. 2018
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| 5 | MAZ, MYB, RB1
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| MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter.
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| Álvaro-Blanco J, Urso K, Chiodo Y, Martín-Cortázar C, Kourani O, Arco PG, Rodríguez-Martínez M, Calonge E, Alcamí J, Redondo JM, Iglesias T, Campanero MR.
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| Nucleic Acids Res 45(17):9960-9975. doi: 10.1093/nar/gkx641.
2017
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| 6 | EP300, HIPK1, MYB, TGFB1I1
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| The adaptor protein ARA55 and the nuclear kinase HIPK1 assist c-Myb in recruiting p300 to chromatin.
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| Bengtsen M, Sørensen L, Aabel L, Ledsaak M, Matre V, Gabrielsen OS.
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| Biochim Biophys Acta 1860(7):751-760. doi: 10.1016/j.bbagrm.2017.05.001. Epub 2017 May 8.
2017
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| 7 | MYB, SETBP1
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| Myb expression is critical for myeloid leukemia development induced by Setbp1 activation.
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| Nguyen N, Vishwakarma BA, Oakley K, Han Y, Przychodzen B, Maciejewski JP, Du Y.
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| Oncotarget ncotarget. 2016 Nov 16. doi: 10.18632/oncotarget.13383. [Epub ahead of print]
2016
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| 8 | MYB, PIAS1
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| PIAS1 binds p300 and behaves as a coactivator or corepressor of the transcription factor c-Myb dependent on SUMO-status.
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| Ledsaak M, Bengtsen M, Molværsmyr AK, Fuglerud BM, Matre V, Eskeland R, Gabrielsen OS.
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| Biochim Biophys Acta 1859(5):705-18. doi: 10.1016/j.bbagrm.2016.03.011.
2016
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| 9 | MYB
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| MYB is a novel regulator of pancreatic tumour growth and metastasis.
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| Srivastava SK, Bhardwaj A, Arora S, Singh S, Azim S, Tyagi N, Carter JE, Wang B, Singh AP.
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| Br J Cancer 113(12):1694-703. doi: 10.1038/bjc.2015.400.
2015
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| 10 | MYB
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| c-Myb Binding Sites in Haematopoietic Chromatin Landscapes.
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| Bengtsen M, Klepper K, Gundersen S, Cuervo I, Drabløs F, Hovig E, Sandve GK, Gabrielsen OS, Eskeland R.
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| PLoS One 10(7):e0133280. doi: 10.1371/journal.pone.0133280.
2015
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| 11 | MYB
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| Role of c-Myb in chondrogenesis.
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| Oralová V, Matalová E, Janečková E, Drobná Krejčí E, Knopfová L, Šnajdr P, Tucker AS, Veselá I, Šmarda J, Buchtová M.
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| Bone 76:97-106. doi: 10.1016/j.bone.2015.02.031.
2015
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| 12 | MYB
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| Myb via TGFβ is required for collagen type 1 production and skin integrity.
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| Sampurno S, Cross R, Pearson H, Kaur P, Malaterre J, Ramsay RG.
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| Growth Factors 33(2):102-12. doi: 10.3109/08977194.2015.1016222.
2015
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| 13 | MYB
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| Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes.
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| Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M.
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| Stem Cells 33(2):479-90. doi: 10.1002/stem.1855.
2015
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| 14 | MYB
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| Myb permits multilineage airway epithelial cell differentiation.
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| Pan JH, Adair-Kirk TL, Patel AC, Huang T, Yozamp NS, Xu J, Reddy EP, Byers DE, Pierce RA, Holtzman MJ, Brody SL.
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| Stem Cells 32(12):3245-56. doi: 10.1002/stem.1814.
2014
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| 15 | BCL11A, DNMT1, MYB
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| Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
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| Roosjen M, McColl B, Kao B, Gearing LJ, Blewitt ME, Vadolas J.
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| FASEB J 28(4):1610-20. doi: 10.1096/fj.13-242669.
2014
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| 16 | MYB, PAX7
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| Pax7 is regulated by cMyb during early neural crest development through a novel enhancer.
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| Vadasz S, Marquez J, Tulloch M, Shylo NA, García-Castro MI.
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| Development 140(17):3691-702. doi: 10.1242/dev.088328.
2013
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| 17 | EP300, MYB, cREBBP
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| Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
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| Kasper LH, Fukuyama T, Lerach S, Chang Y, Xu W, Wu S, Boyd KL, Brindle PK.
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| PLoS One 8(12):e82684. doi: 10.1371/journal.pone.0082684.
2013
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| 18 | MYB
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| c-Myb inhibits myoblast fusion.
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| Kaspar P, Ilencikova K, Zikova M, Horvath O, Cermak V, Bartunek P, Strnad H.
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| PLoS One 8(10):e76742. doi: 10.1371/journal.pone.0076742.
2013
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| 19 | FOXJ1, MYB
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| Myb promotes centriole amplification and later steps of the multiciliogenesis program.
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| Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA.
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| Development 140(20):4277-86. doi: 10.1242/dev.094102.
2013
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| 20 | MYB
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| Myb and the regulation of stem cells in the intestine and brain: a tale of two niches.
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| Malaterre J, Pereira L, Ramsay RG.
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| Adv Exp Med Biol 786:353-68. doi: 10.1007/978-94-007-6621-1_19.
2013
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| 21 | CREBBP, MYB
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| Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.
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| Giri R, Morrone A, Toto A, Brunori M, Gianni S.
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| Proc Natl Acad Sci U S A 110(37):14942-7. doi: 10.1073/pnas.1307337110.
2013
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| 22 | HBS1L, MYB
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| HbA2 levels in normal adults are influenced by two distinct genetic mechanisms. 2013
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| Menzel S, Garner C, Rooks H, Spector TD, Thein SL.
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| Br J Haematol. Jan;160(1):101-5. doi: 10.1111/bjh.12084. Epub 2012 Oct 9. 2013
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| 23 | FBXW5, MYB
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| Fbxw5 suppresses nuclear c-Myb activity via DDB1-Cul4-Rbx1 ligase-mediated sumoylation.
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| Kanei-Ishii C, Nomura T, Egoh A, Ishii S.
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| Biochem Biophys Res Commun 426(1):59-64. doi: 10.1016/j.bbrc.2012.08.032.
2012
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| 24 | MYB
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| Localization of c-MYB in differentiated cells during postnatal molar and alveolar bone development.
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| Lungova V, Buchtova M, Janeckova E, Tucker AS, Knopfova L, Smarda J, Matalova E.
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| Eur J Oral Sci 120(6):495-504. doi: 10.1111/j.1600-0722.2012.01004.x.
2012
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| 25 | ERBIN, MYB
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| c-Myb regulates cell cycle-dependent expression of Erbin: an implication for a novel function of Erbin.
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| Liu D, Shi M, Zhang H, Qian L, Yu M, Hu M, Zhang R, Wang T, Han C, Duan H, Guo N.
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| PLoS One 7(8):e42903. doi: 10.1371/journal.pone.0042903.
2012
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| 26 | MYB, NFIB
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| Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms.
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| Brill LB 2nd, Kanner WA, Fehr A, Andrén Y, Moskaluk CA, Löning T, Stenman G, Frierson HF Jr.
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| Mod Pathol od Pathol. 2011 May 13. [Epub ahead of print]
2011
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| 27 | HBS1L, MYB
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| A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression.
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| Farrell JJ, Sherva RM, Chen ZY, Luo HY, Chu BF, Ha SY, Li CK, Lee AC, Li RC, Li CK, Yuen HL, So JC, Ma ES, Chan LC, Chan V, Sebastiani P, Farrer LA, Baldwin CT, Steinberg MH, Chui DH.
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| Blood 117(18):4935-45. Epub 2011 Mar 8.
2011
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| 28 | GATA1, MYB
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| Identification of a transforming MYB-GATA1 fusion gene in acute basophilic leukemia: a new entity in male infants.
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| Quelen C, Lippert E, Struski S, Demur C, Soler G, Prade N, Delabesse E, Broccardo C, Dastugue N, Mahon FX, Brousset P.
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| Blood 117(21):5719-22. Epub 2011 Apr 7.
2011
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| 29 | MYB
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| MYB is essential for mammary tumorigenesis.
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| Miao RY, Drabsch Y, Cross RS, Cheasley D, Carpinteri S, Pereira L, Malaterre J, Gonda TJ, Anderson RL, Ramsay RG.
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| Cancer Res 71(22):7029-37. doi: 10.1158/0008-5472.CAN-11-1015. Epub 2011 Sep 26.
2011
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| 30 | CASP8AP2, MYB, PIAS1
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| PIAS1 interacts with FLASH and enhances its co-activation of c-Myb.
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| Alm-Kristiansen AH, Lorenzo PI, Molværsmyr AK, Matre V, Ledsaak M, Sæther T, Gabrielsen OS.
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| Mol Cancer 10:21. doi: 10.1186/1476-4598-10-21.
2011
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| 31 | DHRS2, MDM2, MYB, TP53
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| Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.
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| Deisenroth C, Thorner AR, Enomoto T, Perou CM, Zhang Y.
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| Mol Cell Biol 30(16):3981-93. Epub 2010 Jun 14.PMID: 20547751 2010
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| 32 | MYB, SNAI2
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| Expression of Slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin.
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| Tanno B, Sesti F, Cesi V, Bossi G, Ferrari-Amorotti G, Bussolari R, Tirindelli D, Calabretta B, Raschellà G.
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| J Biol Chem 285(38):29434-45. Epub 2010 Jul 11.
2010
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| 33 | HIPK1, MYB
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| HIPK1 interacts with c-Myb and modulates its activity through phosphorylation.
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| Matre V, Nordgård O, Alm-Kristiansen AH, Ledsaak M, Gabrielsen OS.
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| Biochem Biophys Res Commun 388(1):150-4. Epub 2009 Jul 30.
2009
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| 34 | BTHAL, HBS1L, MYB, SICA
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| Discovering the genetics underlying foetal haemoglobin production in adults.
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| Thein SL, Menzel S.
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| Br J Haematol 145(4):455-67. Epub 2008 Mar 2. Review.PMID: 19344402 2009
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| 35 | HBS1L, MYB
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| Control of fetal hemoglobin: new insights emerging from genomics and clinical implications.
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| Thein SL, Menzel S, Lathrop M, Garner C.
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| Hum Mol Genet 18(R2):R216-23. Review.PMID: 19808799 2009
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| 36 | HBS1L, MYB
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| The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells.
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| Wahlberg K, Jiang J, Rooks H, Jawaid K, Matsuda F, Yamaguchi M, Lathrop M, Thein SL, Best S.
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| Blood 114(6):1254-62. Epub 2009 Jun 15.PMID: 19528534 2009
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| 37 | MYB, NFIB
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| Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck.
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| Persson M, Andrén Y, Mark J, Horlings HM, Persson F, Stenman G.
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| Proc Natl Acad Sci U S A 106(44):18740-4. Epub 2009 Oct 19.
2009
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| 38 | FBXW7, MYB, NLK
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| Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation.
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| Kanei-Ishii C, Nomura T, Takagi T, Watanabe N, Nakayama KI, Ishii S.
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| J Biol Chem 283(45):30540-8. Epub 2008 Sep 2.
2008
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| 39 | CASP8AP2, MYB, POLR2A
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| FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci.
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| Alm-Kristiansen AH, Saether T, Matre V, Gilfillan S, Dahle O, Gabrielsen OS.
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| Oncogene 27(34):4644-56. Epub 2008 Apr 14. 2008
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| 40 | HBS1L, MYB
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| The HBS1L-MYB intergenic region on chromosome 6q23 is a quantitative trait locus controlling fetal haemoglobin level in carriers of beta-thalassaemia.
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| So CC, Song YQ, Tsang ST, Tang LF, Chan AY, Ma ES, Chan LC.
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| J Med Genet 45(11):745-51. Epub 2008 Aug 12.PMID: 18697826 2008
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| 41 | HBS1L,MYB
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| Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.
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| Thein SL, Menzel S, Peng X, Best S, Jiang J, Close J, Silver N, Gerovasilli A, Ping C, Yamaguchi M, Wahlberg K, Ulug P, Spector TD, Garner C, Matsuda F, Farrall M, Lathrop M.
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| Proc Natl Acad Sci U S A 104(27):11346-51. Epub 2007 Jun 25. 2007
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| 42 | MYB
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| Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells.
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| Drabsch Y, Hugo H, Zhang R, Dowhan DH, Miao YR, Gewirtz AM, Barry SC, Ramsay RG, Gonda TJ.
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| Proc Natl Acad Sci U S A 104(34):13762-7. Epub 2007 Aug 9. 2007
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| 43 | HBS1L, MYB
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| The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans.
|
| Menzel S, Jiang J, Silver N, Gallagher J, Cunningham J, Surdulescu G, Lathrop M, Farrall M, Spector TD, Thein SL.
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| Blood 110(10):3624-6. Epub 2007 Aug 21.PMID: 17712044 2007
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| 44 | MYB, TRAF
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| TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation.
|
| Morita Y, Kanei-Ishii C, Nomura T, Ishii S.
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| Mol Biol Cell 16(11):5433-44. Epub 2005 Sep 14.PMID: 16162816 2005
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| 45 | MAF, MYB
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| c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation.
|
| Hedge SP, Kumar A, Kurschner C, Shapiro LH.
|
| Mol Cell Biol 18(5):2729-37. 1998
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| 46 | MYB
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| The Myb oncogene product induces DNA-bending.
|
| Saikumar P, et al.
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| Oncogene 9 : 1279-1287. 1994
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| 47 | D6S132, D6S133, D6S148, D6S150, D6S170, D6S2, D6S201, D6S21, D6S22, D6S25, D6S32, D6S33, D6S37, D6S39, D6S43, D6S44, D6S48, D6S6, D6S85, MYB
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| Subregional localization of 20 single-copy loci to chromosome 6 by fluorescence in situ hybridization.
|
| Rao PH, et al.
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| Genomics 16 : 426-430. 1993
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| 48 | MYB
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| Acute- and chronic-phase chronic myelogenous leukemia colony-forming units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides.
|
| Ratajczak MZ, et al.
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| Blood 79 : 1956-1961. 1992
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| 49 | ARG1, D6S33, MYB
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| Genetic linkage group (ARG1-D6S33-MYB) on chromosome 6q containing the arginase-1 and MYB genes.
|
| Nguyen J, et al.
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| Cytogenet Cell Genet 54 : 95-96. 1990
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| 50 | MYB
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| Alternative splicing of the human c-myb gene.
|
| Westin EH, Gorse KM, Clarke MF.
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| Oncogene 5(8):1117-24.
1990
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| 51 | MYB
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| Molecular mapping of the oncogene MYB and rearrangements in malignant melanoma.
|
| Meese E, et al.
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| Genes Chromosomes Cancer 1 : 88-94. 1989
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| 52 | MYB
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| Sublocalization of c-myb to 6q21-q23 by in situ hybridization and c-myb expression in a human teratocarcinoma with 6q rearrangements.
|
| Janssen JW, Vernole P, de Boer PA, Oosterhuis JW, Collard JG.
|
| Cytogenet Cell Genet 41 : 129-135. 1986
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| 53 | MYB
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| EcoRI RFLP linked to the human myb gene.
|
| Dozier C, et al.
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| Nucleic Acids Res 14 : 1928. 1986
|
| 54 | MYB, NRAS
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| Chromosomal localization of N-ras, K-ras-1, K-ras-2, and myb oncogenes in human cells.
|
| McBride OW, et al.
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| (HGM7) Cytogenet Cell Genet 37 : 534-535. 1984
|
| 55 | EGFR, KRAS1P, MOS, MYB, MYC
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| Human proto-oncogene assignments.
|
| Sakaguchi AY, et al.
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| (HGM7) Cytogenet Cell Genet 37 : 572-573. 1984
|
| 56 | MYB
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| Regional assignment of human protooncogene c-myb to 6q21->qter.
|
| Zabel BU, et al.
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| Somat Cell Mol Genet 10 : 105-108. 1984
|
| 57 | FES, MYB
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| Chromosomal sublocalization of human c-myb and c-fes cellular onc genes.
|
| Harper ME, et al.
|
| Nature 304 : 169-171. 1983
|
| 58 | FES, MYB
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| Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis onc genes.
|
| Dalla-Favera R, et al.
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| Proc Natl Acad Sci U S A 79 : 4714-4717. 1982
|