1 | MUC5AC, MUC5B
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| Structural and genetic diversity in the secreted mucins MUC5AC and MUC5B.
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| Plender EG, Prodanov T, Hsieh P, Nizamis E, Harvey WT, Sulovari A, Munson KM, Kaufman EJ, O'Neal WK, Valdmanis PN, Marschall T, Bloom JD, Eichler EE.
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| Am J Hum Genet. Aug 8;111(8):1700-1716. doi: 10.1016/j.ajhg.2024.06.007. Epub 2024 Jul 10. 2024
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2 | MUC5AC
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| Understanding the Clinical Significance of MUC5AC in Biliary Tract Cancers.
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| Benson KK, Sheel A, Rahman S, Esnakula A, Manne A.
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| Cancers (Basel). Jan 9;15(2):433. doi: 10.3390/cancers15020433. 2023
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3 | MUC5AC, STING1
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| Oxidative stress induces MUC5AC expression through mitochondrial damage-dependent STING signaling in human bronchial epithelial cells.
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| Nishida Y, Yagi H, Ota M, Tanaka A, Sato K, Inoue T, Yamada S, Arakawa N, Ishige T, Kobayashi Y, Arakawa H, Takizawa T.
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| FASEB Bioadv. Feb 17;5(4):171-181. doi: 10.1096/fba.2022-00081. 2023
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4 | MUC5AC, MUC5B
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| MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.
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| Song D, Iverson E, Kaler L, Boboltz A, Scull MA, Duncan GA.
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| Sci Adv. Nov 25;8(47):eabq5049. doi: 10.1126/sciadv.abq5049. Epub 2022 Nov 25. 2022
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5 | MUC5AC, MUC5B
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| Assembly and organization of the N-terminal region of mucin MUC5AC: Indications for structural and functional distinction from MUC5B.
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| Carpenter J, Wang Y, Gupta R, Li Y, Haridass P, Subramani DB, Reidel B, Morton L, Ridley C, O'Neal WK, Buisine MP, Ehre C, Thornton DJ, Kesimer M.
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| Proc Natl Acad Sci U S A. Sep 28;118(39):e2104490118. doi: 10.1073/pnas.2104490118. 2021
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6 | MUC5AC, NOX4, TGFB3
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| TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway.
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| Zhang Y, Tang HM, Liu CF, Yuan XF, Wang XY, Ma N, Xu GF, Wang SP, Deng J, Wang X.
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| Mediators Inflamm. Dec 31;2019:3153240. doi: 10.1155/2019/3153240. 2019
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7 | MUC5AC, MUC5B
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| Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways.
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| Okuda K, Chen G, Subramani DB, Wolf M, Gilmore RC, Kato T, Radicioni G, Kesimer M, Chua M, Dang H, Livraghi-Butrico A, Ehre C, Doerschuk CM, Randell SH, Matsui H, Nagase T, O'Neal WK, Boucher RC.
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| Am J Respir Crit Care Med. Mar 15;199(6):715-727. doi: 10.1164/rccm.201804-0734OC. 2019
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8 | KDR, MUC5AC, VEGFA
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| Upregulation of MUC5AC by VEGF in human primary bronchial epithelial cells: implications for asthma.
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| Kim SH, Pei QM, Jiang P, Liu J, Sun RF, Qian XJ, Liu JB.
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| Respir Res. Dec 12;20(1):282. doi: 10.1186/s12931-019-1245-1. 2019
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9 | MUC5AC, MUC5B
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| Airway Mucus and Asthma: The Role of MUC5AC and MUC5B.
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| Bonser LR, Erle DJ.
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| J Clin Med. Nov 29;6(12):112. doi: 10.3390/jcm6120112. 2017
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10 | ITGB4, MUC5AC, PTK2
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| MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.
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| Lakshmanan I, Rachagani S, Hauke R, Krishn SR, Paknikar S, Seshacharyulu P, Karmakar S, Nimmakayala RK, Kaushik G, Johansson SL, Carey GB, Ponnusamy MP, Kaur S, Batra SK, Ganti AK.
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| Oncogene. Aug 4;35(31):4112-21. doi: 10.1038/onc.2015.478. Epub 2016 Jan 11. 2016
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11 | MUC5AC
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| Prognostic value of Muc5AC in gastric cancer: A meta-analysis.
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| Zhang CT, He KC, Pan F, Li Y, Wu J.
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| World J Gastroenterol. Sep 28;21(36):10453-60. doi: 10.3748/wjg.v21.i36.10453. 2015
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12 | MUC5AC
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| The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
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| Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF.
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| Nat Commun. Feb 17;6:6281. doi: 10.1038/ncomms7281. 2015
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13 | MUC5AC, TLX2, TRPM5
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| TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells.
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| Mitrovic S, Nogueira C, Cantero-Recasens G, Kiefer K, Fernández-Fernández JM, Popoff JF, Casano L, Bard FA, Gomez R, Valverde MA, Malhotra V.
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| Elife 2:e00658. doi: 10.7554/eLife.00658.
2013
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14 | ELANE, F2RL1, MUC5AC
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| Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2.
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| Zhou J, Perelman JM, Kolosov VP, Zhou X.
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| Mol Cell Biochem 377(1-2):75-85. doi: 10.1007/s11010-013-1572-3. Epub 2013 Feb 8.
2013
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15 | MUC5AC
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| MUC5AC expression through bidirectional communication of Notch and epidermal growth factor receptor pathways.
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| Kang JH, Lee EH, Park SW, Chung IY.
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| J Immunol 187(1):222-9. Epub 2011 May 27.
2011
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16 | MUC5AC
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| Inhibition of E-cadherin dependent cell-cell contact promotes MUC5AC mucin production through the activation of epidermal growth factor receptors.
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| Iwashita J, Ose K, Ito H, Murata J, Abe T.
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| Biosci Biotechnol Biochem 75(4):688-93. Epub 2011 Apr 22.
2011
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17 | MUC5AC
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| Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer.
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| Hoshi H, Sawada T, Uchida M, Saito H, Iijima H, Toda-Agetsuma M, Wada T, Yamazoe S, Tanaka H, Kimura K, Kakehashi A, Wei M, Hirakawa K, Wanibuchi H.
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| Int J Oncol 38(3):619-27. doi: 10.3892/ijo.2011.911. Epub 2011 Jan 18.
2011
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18 | MUC5AC, MUC5B, NRG1
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| Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.
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| Kettle R, Simmons J, Schindler F, Jones P, Dicker T, Dubois G, Giddings J, Van Heeke G, Jones CE.
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| Am J Respir Cell Mol Biol 42(4):472-81. Epub 2009 Jun 25.
2010
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19 | MUC5AC
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| Expression of MUC5AC, an early marker of pancreatobiliary cancer, is regulated by DNA methylation in the distal promoter region in cancer cells.
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| Yamada N, Nishida Y, Yokoyama S, Tsutsumida H, Houjou I, Kitamoto S, Goto M, Higashi M, Yonezawa S.
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| J Hepatobiliary Pancreat Sci 17(6):844-54. Epub 2010 Apr 14.
2010
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20 | MUC2, MUC5AC, MUC5B, MUC6
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| Variants of MUC5B minisatellites and the susceptibility of bladder cancer.
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| Ahn EK, Kim WJ, Kwon JA, Choi PJ, Kim WJ, Sunwoo Y, Heo J, Leem SH.
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| DNA Cell Biol 28(4):169-76.
2009
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21 | MUC5AC
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| MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients.
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| Caramori G, Casolari P, Di Gregorio C, Saetta M, Baraldo S, Boschetto P, Ito K, Fabbri LM, Barnes PJ, Adcock IM, Cavallesco G, Chung KF, Papi A.
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| Histopathology 55(3):321-31.
2009
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22 | MUC5AC, MUC5B
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| MUC5B is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease.
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| Kirkham S, Kolsum U, Rousseau K, Singh D, Vestbo J, Thornton DJ.
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| Am J Respir Crit Care Med 178(10):1033-9. Epub 2008 Sep 5.
2008
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23 | MUC5AC, MUC5B
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| The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.
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| Ding GQ, Zheng CQ.
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| Am J Rhinol 21(3):359-66.
2007
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24 | MUC1, MUC5AC, MUC6
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| Mucin expression profile in pancreatic cancer and the precursor lesions.
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| Nagata K, Horinouchi M, Saitou M, Higashi M, Nomoto M, Goto M, Yonezawa S.
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| J Hepatobiliary Pancreat Surg 14(3):243-54. Epub 2007 May 29. Review.
2007
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25 | MUC5AC, MUC5B
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| Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.
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| Elsheikh MN, Mahfouz ME.
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| Laryngoscope 116(3):365-9.
2006
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26 | MUC5AC, DUOX1
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| Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells.
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| Shao MX, Nadel JA.
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| Proc Natl Acad Sci U S A 102(3):767-72. Epub 2005 Jan 07. 2005
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27 | MUC5AC, MUC5B
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| MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.
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| Henke MO, Renner A, Huber RM, Seeds MC, Rubin BK.
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| Am J Respir Cell Mol Biol 31(1):86-91. Epub 2004 Feb 26.
2004
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28 | MUC15, MUC1, MUC2, MUC3A, MUC4, MUC5AC, MUC5B, MUC6, MUC7, MUC8, OVGP1, MUC12, MUC13, MUC16
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| Isolation and characterization of MUC15, a novel cell membrane-associated mucin.
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| Pallesen LT, Berglund L, Rasmussen LK, Petersen TE, Rasmussen JT.
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| Eur J Biochem 269(11):2755-63. 2002
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29 | MUC5AC, MUC6
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| Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.
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| Kim GE, Bae HI, Park HU, Kuan SF, Crawley SC, Ho JJ, Kim YS.
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| Gastroenterology 123(4):1052-60. 2002
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30 | MUC5AC
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| Human mucin gene MUC5AC: organization of its 5'-region and central repetitive region.
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| Escande F, Aubert JP, Porchet N, Buisine MP.
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| Biochem J 358(Pt 3):763-72. 2001
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31 | MUC5AC
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| Physical characterization of the MUC5AC mucin: a highly oligomeric glycoprotein whether isolated from cell culture or in vivo from respiratory mucous secretions.
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| Sheehan JK, Brazeau C, Kutay S, Pigeon H, Kirkham S, Howard M, Thornton DJ.
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| Biochem J 347 Pt 1:37-44. 2000
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32 | MUC5AC, MUC6
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| Aberrant expression of MUC5AC and MUC6 gastric mucin genes in colorectal polyps.
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| Bartman AE, et al.
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| Int J Cancer 80 : 210-218. 1999
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33 | MUC2, MUC3A, MUC4, MUC5AC, MUC5B, MUC6
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| Human mucin genes MUC2, MUC3, MUC4, MUC5AC,MUC5B, and MUC6 express stable and extremely large mRNAs and exhibit a variable length polymorphism. An improved method to analyze large mrnas.
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| Debailleul V, Laine A, Huet G, Mathon P, d'Hooghe MC, Aubert JP, Porchet N.
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| J Biol Chem 273(2):881-90. 1998
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34 | MUC2, MUC5AC, MUC5B, MUC6
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| Variable number tandem repeat polymorphism of the mucin genes located in the complex on 11p15.5.
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| Vinall LE, et al.
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| Hum Genet 102 : 357-366. 1998
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35 | MUC5AC
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| Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts.
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| Li D, et al.
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| J Biol Chem 273 : 6812-6820. 1998
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36 | MUC5AC
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| Molecular cloning of human gastric mucin MUC5AC reveals conserved cysteine-rich D-domains and a putative leucine zipper motif.
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| van de Bovenkamp JH, et al.
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| Biochem Biophys Res Commun 245 : 853-859. 1998
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37 | MUC5AC
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| Genomic organization of the 3'-region of the human MUC5AC mucin gene : additional evidence for a common ancestral gene for the 11p15.5 mucin gene family.
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| Buisine MP, et al.
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| Biochem J 332 : 729-738. 1998
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38 | MUC2, MUC4, MUC5AC
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| Mucin gene expression in human embryonic and fetal intestine.
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| Buisine MP, et al.
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| Gut 43 : 519-524. 1998
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39 | MUC1, MUC2, MUC4, MUC5AC
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| Mucin gene expression in ovarian cancers.
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| Giuntoli RL, et al.
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| Cancer Res 58 : 5546-5550. 1998
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40 | MUC2, MUC5AC, MUC5B, MUC6, MUCX
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| Human mucin genes assigned to 11p15.5 : identification and organization of a cluster of genes.
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| Pigny P, et al.
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| Genomics 38 : 340-352. 1996
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41 | MUC4, MUC5AC, MUC5B
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| Human mucin genes : genomic organization and expression of MUC4, MUC5AC and MUC5B.
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| Porchet N, et al.
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| Biochem Soc Trans 23 : 800-805. 1995
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42 | MUC5AC
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| The MUC5AC gene : RFLP analysis with the Jer58 probe.
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| Pigny P, et al.
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| Hum Genet 96 : 367-368. 1995
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43 | MUC5AC
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| Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5AC).
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| Meerzaman D, et al.
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| J Biol Chem 269 : 12932-12939. 1994
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44 | MUC5AC, MUC5B, MUC5R
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| Assignment of human tracheobronchial mucin gene(s) to 11p15 and a tracheobronchial mucin-related sequence to chromosome 13.
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| Nguyen Van Cong, et al.
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| Hum Genet 86 : 167-172. 1990
|