| 1 | HMBOX1, MT2A
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| HMBOX1 interacts with MT2A to regulate autophagy and apoptosis in vascular endothelial cells.
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| Ma H, Su L, Yue H, Yin X, Zhao J, Zhang S, Kung H, Xu Z, Miao J.
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| Sci Rep 5:15121. doi: 10.1038/srep15121.
2015
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| 2 | MT2A
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| Metallothionein 2A genetic polymorphism and its correlation to coronary heart disease.
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| Yang XY, Sun JH, Ke HY, Chen YJ, Xu M, Luo GH.
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| Eur Rev Med Pharmacol Sci 18(24):3747-53.
2014
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| 3 | AHR, MT2A
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| The aryl hydrocarbon receptor and glucocorticoid receptor interact to activate human metallothionein 2A.
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| Sato S, Shirakawa H, Tomita S, Tohkin M, Gonzalez FJ, Komai M.
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| Toxicol Appl Pharmacol 273(1):90-9. doi: 10.1016/j.taap.2013.08.017. Epub 2013 Aug 28.
2013
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| 4 | MT2A
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| Metallothionein 2a gene expression is increased in subcutaneous adipose tissue of type 2 diabetic patients.
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| Haynes V, Connor T, Tchernof A, Vidal H, Dubois S.
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| Mol Genet Metab 108(1):90-4. doi: 10.1016/j.ymgme.2012.10.012. Epub 2012 Oct 18.
2013
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| 5 | MT1F, MT2A
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| Metallothionein 1F and 2A overexpression predicts poor outcome of non-small cell lung cancer patients.
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| Werynska B, Pula B, Muszczynska-Bernhard B, Gomulkiewicz A, Piotrowska A, Prus R, Podhorska-Okolow M, Jankowska R, Dziegiel P.
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| Exp Mol Pathol 94(1):301-8. doi: 10.1016/j.yexmp.2012.10.006. Epub 2012 Oct 9.
2013
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| 6 | MT1A, MT2A
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| Increased metallothionein I/II expression in patients with temporal lobe epilepsy.
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| Peixoto-Santos JE, Galvis-Alonso OY, Velasco TR, Kandratavicius L, Assirati JA, Carlotti CG, Scandiuzzi RC, Serafini LN, Leite JP.
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| PLoS One 7(9):e44709. doi: 10.1371/journal.pone.0044709. Epub 2012 Sep 18.
2012
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| 7 | MT2A
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| The effects of metallothionein 2A polymorphism on placental cadmium accumulation: Is metallothionein a modifiying factor in transfer of micronutrients to the fetus?
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| Tekin D, Kayaaltı Z, Aliyev V, Söylemezoğlu T.
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| J Appl Toxicol 32(4):270-5. doi: 10.1002/jat.1661. Epub 2011 Feb 15.
2012
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| 8 | MT1F, MT2A
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| Downregulation of metallothionein 1F, a putative oncosuppressor, by loss of heterozygosity in colon cancer tissue.
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| Yan DW, Fan JW, Yu ZH, Li MX, Wen YG, Li DW, Zhou CZ, Wang XL, Wang Q, Tang HM, Peng ZH.
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| Biochim Biophys Acta 1822(6):918-26. doi: 10.1016/j.bbadis.2012.02.021. Epub 2012 Mar 9.
2012
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| 9 | MT2A
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| The potential effect of metallothionein 2A -5A/G single nucleotide polymorphism on blood cadmium, lead, zinc and copper levels.
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| Kayaaltı Z, Aliyev V, Söylemezoğlu T.
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| Toxicol Appl Pharmacol 256(1):1-7. doi: 10.1016/j.taap.2011.06.023. Epub 2011 Jul 13.
2011
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| 10 | MT2A
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| Metallothionein-2A overexpression increases the expression of matrix metalloproteinase-9 and invasion of breast cancer cells.
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| Kim HG, Kim JY, Han EH, Hwang YP, Choi JH, Park BH, Jeong HG.
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| FEBS Lett 585(2):421-8. doi: 10.1016/j.febslet.2010.12.030. Epub 2010 Dec 25.
2011
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| 11 | MT1A, MT1F, MT2A
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| Modulation of metallothionein isoforms is associated with collagen deposition in proliferating keloid fibroblasts in vitro.
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| Toh PP, Li JJ, Yip GW, Lo SL, Guo CH, Phan TT, Bay BH.
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| Exp Dermatol 19(11):987-93. doi: 10.1111/j.1600-0625.2010.01124.x. Epub 2010 Aug 31. 2010
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| 12 | MT1A, MT2A
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| The polymorphism of core promoter region on metallothionein 2A-metal binding protein in Turkish population.
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| Kayaaltı Z, Söylemezoğlu T.
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| Mol Biol Rep ol Biol Rep. 2009 Jul 2. [Epub ahead of print]
2009
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| 13 | MT2A
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| Silencing the Metallothionein-2A gene inhibits cell cycle progression from G1- to S-phase involving ATM and cdc25A signaling in breast cancer cells.
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| Lim D, Jocelyn KM, Yip GW, Bay BH.
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| Cancer Lett 276(1):109-17. Epub 2008 Dec 4.
2009
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| 14 | MT1A, MT2A, TTR
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| Transthyretin interacts with metallothionein 2.
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| Gonçalves I, Quintela T, Baltazar G, Almeida MR, Saraiva MJ, Santos CR.
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| Biochemistry 47(8):2244-51. Epub 2008 Feb 1.
2008
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| 15 | MT1A, MT2A
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| Metal exchange in metallothioneins: a novel structurally significant Cd(5) species in the alpha domain of human metallothionein 1a.
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| Rigby Duncan KE, Kirby CW, Stillman MJ.
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| FEBS J 275(9):2227-39.
2008
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| 16 | MT2A
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| Metallothionein disulfides are present in metallothionein-overexpressing transgenic mouse heart and increase under conditions of oxidative stress.
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| Feng W, Benz FW, Cai J, Pierce WM, Kang YJ.
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| J Biol Chem 281(2):681-7. Epub 2005 Oct 21. 2006
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| 17 | MT1A, MT2A
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| Effect of metallothionein on cell viability and its interactions with cadmium and zinc in HEK293 cells.
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| Li J, Liu Y, Ru B.
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| Cell Biol Int 29(10):843-8.
2005
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| 18 | MT2A
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| Metallothionein can function as a chaperone for zinc uptake transport into prostate and liver mitochondria.
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| Costello LC, Guan Z, Franklin RB, Feng P.
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| J Inorg Biochem 98(4):664-6.
2004
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| 19 | SPINK7, MT2A
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| ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis.
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| Cui Y, Wang J, Zhang X, Lang R, Bi M, Guo L, Lu SH.
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| Biochem Biophys Res Commun 302(4):904-15. 2003
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| 20 | MT1E, MT1F, MT1G, MT1H, MT1L, MT2A
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| Identification and spatial analysis of metallothioneins expressed by the adult human lens.
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| Oppermann B, Zhang W, Magabo K, Kantorow M.
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| Invest Ophthalmol Vis Sci 42(1):188-93.
2001
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| 21 | MT2A
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| A BamHI RFLP at MT2A on human chromosome 16.
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| Bates LJ, et al.
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| Nucleic Acids Res 16 : 9071. 1988
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| 22 | MT2A, FRA16A, FRA16B
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| Linkage analysis of markers near fragile sites on human chromosome 16.
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| Mulley JC, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 665. 1987
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| 23 | MT1@, MT2A
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| A 5' flanking region of the metallothionein, MT2A, gene identifies two moderately frequent RFLPs.
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| Hyland VJ, et al.
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| Nucleic Acids Res 15 : 1350. 1987
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| 24 | MT1@, MT2A
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| Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia.
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| Le Beau MM, et al.
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| Nature 313 : 709-711. 1985
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| 25 | MT1@, MT2A, MT1A, MT1B, MT1CP, MT1DP, MT1E, MT1F, MT1G, MT1H, MT1IP, MT1JP, MT1M, MT1L, MT1X
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| Human metallothionein genes are clustered on chromosome 16.
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| Karin M, et al.
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| Proc Natl Acad Sci U S A 81 : 5494-5498. 1984
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| 26 | MT1@, MT2A, MT2P1, MTL1, MTL2, MTL3, MTL4
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| Chromosomal location of human metallothionein genes : implications for Menkes' disease.
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| Schmidt CJ, et al.
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| Science 224 : 1104-1106. 1984
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