| 1 | ASH2L, DNMT1, MT1A, UHRF1, YWHAE, ZNF479
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| ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma
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| Wu YJ, Ko BS, Liang SM, Lu YJ, Jan YJ, Jiang SS, Shyue SK, Chen L, Liou JY.
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| Cell Death Dis. May 28;10(6):408. doi: 10.1038/s41419-019-1651-9. 2019
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| 2 | MT1A
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| Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System.
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| Siddiq MM, Hannila SS, Carmel JB, Bryson JB, Hou J, Nikulina E, Willis MR, Mellado W, Richman EL, Hilaire M, Hart RP, Filbin MT.
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| J Biol Chem 290(26):16343-56. doi: 10.1074/jbc.M114.630574. Epub 2015 May 6.
2015
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| 3 | MT1A, SLC30A1
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| Suppression of placental metallothionein 1 and zinc transporter 1 mRNA expressions contributes to fetal heart malformations caused by maternal zinc deficiency.
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| Liu C, He X, Hong X, Kang F, Chen S, Wang Q, Chen X, Hu D, Sun Q.
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| Cardiovasc Toxicol 14(4):329-38. doi: 10.1007/s12012-014-9256-0.
2014
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| 4 | MT1A, SPI1
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| Epigenetic regulation of the metallothionein-1A promoter by PU.1 during differentiation of THP-1 cells.
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| Suzuki S, Nakano H, Takahashi S.
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| Biochem Biophys Res Commun 433(3):349-53. doi: 10.1016/j.bbrc.2013.03.007. Epub 2013 Mar 15.
2013
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| 5 | MT1A, MT2A
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| Increased metallothionein I/II expression in patients with temporal lobe epilepsy.
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| Peixoto-Santos JE, Galvis-Alonso OY, Velasco TR, Kandratavicius L, Assirati JA, Carlotti CG, Scandiuzzi RC, Serafini LN, Leite JP.
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| PLoS One 7(9):e44709. doi: 10.1371/journal.pone.0044709. Epub 2012 Sep 18.
2012
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| 6 | CCS, MT1A
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| Roles of copper chaperone for superoxide dismutase 1 and metallothionein in copper homeostasis.
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| Miyayama T, Ishizuka Y, Iijima T, Hiraoka D, Ogra Y.
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| Metallomics 3(7):693-701. doi: 10.1039/c1mt00016k. Epub 2011 Mar 15. 2011
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| 7 | MT1A, MT1F, MT2A
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| Modulation of metallothionein isoforms is associated with collagen deposition in proliferating keloid fibroblasts in vitro.
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| Toh PP, Li JJ, Yip GW, Lo SL, Guo CH, Phan TT, Bay BH.
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| Exp Dermatol 19(11):987-93. doi: 10.1111/j.1600-0625.2010.01124.x. Epub 2010 Aug 31. 2010
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| 8 | MT1A
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| Metallothionein I isoform mRNA expression in peripheral lymphocytes as a biomarker for occupational cadmium exposure.
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| Chang X, Jin T, Chen L, Nordberg M, Lei L.
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| Exp Biol Med (Maywood) 234(6):666-72. Epub 2009 Apr 9.
2009
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| 9 | MT1A, MT2A
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| The polymorphism of core promoter region on metallothionein 2A-metal binding protein in Turkish population.
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| Kayaaltı Z, Söylemezoğlu T.
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| Mol Biol Rep ol Biol Rep. 2009 Jul 2. [Epub ahead of print]
2009
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| 10 | MT1A, MT2A, TTR
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| Transthyretin interacts with metallothionein 2.
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| Gonçalves I, Quintela T, Baltazar G, Almeida MR, Saraiva MJ, Santos CR.
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| Biochemistry 47(8):2244-51. Epub 2008 Feb 1.
2008
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| 11 | MT1A, MT2A
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| Metal exchange in metallothioneins: a novel structurally significant Cd(5) species in the alpha domain of human metallothionein 1a.
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| Rigby Duncan KE, Kirby CW, Stillman MJ.
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| FEBS J 275(9):2227-39.
2008
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| 12 | MT1A
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| Polymorphisms in metallothionein-1 and -2 genes associated with the risk of type 2 diabetes mellitus and its complications.
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| Yang L, Li H, Yu T, Zhao H, Cherian MG, Cai L, Liu Y.
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| Am J Physiol Endocrinol Metab 294(5):E987-92. Epub 2008 Mar 18.
2008
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| 13 | MT1A, MT2A
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| Effect of metallothionein on cell viability and its interactions with cadmium and zinc in HEK293 cells.
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| Li J, Liu Y, Ru B.
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| Cell Biol Int 29(10):843-8.
2005
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| 14 | MT1A, VEZF1
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| Metallothionein 1 is a downstream target of vascular endothelial zinc finger 1 (VEZF1) in endothelial cells and participates in the regulation of angiogenesis.
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| Miyashita H, Sato Y.
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| Endothelium 12(4):163-70.PMID: 16162438 2005
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| 15 | MT1@, MT2A, MT1A, MT1B, MT1CP, MT1DP, MT1E, MT1F, MT1G, MT1H, MT1IP, MT1JP, MT1M, MT1L, MT1X
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| Human metallothionein genes are clustered on chromosome 16.
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| Karin M, et al.
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| Proc Natl Acad Sci U S A 81 : 5494-5498. 1984
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