Citations for
1FAP4, MSH3
Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.
Adam R, Spier I, Zhao B, Kloth M, Marquez J, Hinrichsen I, Kirfel J, Tafazzoli A, Horpaopan S, Uhlhaas S, Stienen D, Friedrichs N, Altmüller J, Laner A, Holzapfel S, Peters S, Kayser K, Thiele H, Holinski-Feder E, Marra G, Kristiansen G, Nöthen MM, Büttner R, Möslein G, Betz RC, Brieger A, Lifton RP, Aretz S.
Am J Hum Genet 99(2):337-51. doi: 10.1016/j.ajhg.2016.06.015. Epub 2016 Jul 28. 2016
2MSH2, MSH3
MSH3 Promotes Dynamic Behavior of Trinucleotide Repeat Tracts In Vivo.
Williams GM, Surtees JA.
Genetics 200(3):737-54. doi: 10.1534/genetics.115.177303. Epub 2015 May 11. 2015
3MSH2, MSH3, MSH6
Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.
Radhakrishnan R, Li Y, Xiang S, Yuan F, Yuan Z, Telles E, Fang J, Coppola D, Shibata D, Lane WS, Zhang Y, Zhang X, Seto E.
J Biol Chem 290(37):22795-804. doi: 10.1074/jbc.M114.612945. Epub 2015 Jul 28. 2015
4MLH1, MLH3, MSH1, MSH3
Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease.
Rogacheva MV, Manhart CM, Chen C, Guarne A, Surtees J, Alani E.
J Biol Chem 289(9):5664-73. doi: 10.1074/jbc.M113.534644. Epub 2014 Jan 8. 2014
5MSH2, MSH3
The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair.
van Oers JM, Edwards Y, Chahwan R, Zhang W, Smith C, Pechuan X, Schaetzlein S, Jin B, Wang Y, Bergman A, Scharff MD, Edelmann W.
Oncogene 33(30):3939-46. doi: 10.1038/onc.2013.365. Epub 2013 Sep 9. 2014
6MSH2, MSH3
Distinct requirements within the Msh3 nucleotide binding pocket for mismatch and double-strand break repair.
Kumar C, Williams GM, Havens B, Dinicola MK, Surtees JA.
J Mol Biol 425(11):1881-98. doi: 10.1016/j.jmb.2013.02.024. Epub 2013 Feb 28. 2013
7MSH2, MSH3
Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions.
Kantartzis A, Williams GM, Balakrishnan L, Roberts RL, Surtees JA, Bambara RA.
Cell Rep 2(2):216-22. doi: 10.1016/j.celrep.2012.06.020. Epub 2012 Aug 2. 2012
8MSH2, MSH3
Conformational trapping of mismatch recognition complex MSH2/MSH3 on repair-resistant DNA loops.
Lang WH, Coats JE, Majka J, Hura GL, Lin Y, Rasnik I, McMurray CT.
Proc Natl Acad Sci U S A 108(42):E837-44. doi: 10.1073/pnas.1105461108. Epub 2011 Sep 29. 2011
9MSH2, MSH3
Functional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separation.
Dowen JM, Putnam CD, Kolodner RD.
Mol Cell Biol 30(13):3321-8. doi: 10.1128/MCB.01558-09. Epub 2010 Apr 26. 2010
10MSH2, MSH3
Mismatch Recognition Protein MutS{beta} Does Not Hijack (CAG)n Hairpin Repair in Vitro.
Tian L, Hou C, Tian K, Holcomb NC, Gu L, Li GM.
J Biol Chem 284(31):20452-6. Epub 2009 Jun 12. 2009
11MLH3, MSH2, MSH3
Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair.
Charbonneau N, Amunugama R, Schmutte C, Yoder K, Fishel R.
Cancer Biol Ther 8(14):1411-20. Epub 2009 Jul 30. 2009
12MSH3
Mismatch repair gene MSH3 polymorphism is associated with the risk of sporadic prostate cancer.
Hirata H, Hinoda Y, Kawamoto K, Kikuno N, Suehiro Y, Okayama N, Tanaka Y, Dahiya R.
J Urol 179(5):2020-4. doi: 10.1016/j.juro.2008.01.009. Epub 2008 Mar 20. 2008
13MSH2, MSH3
Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination.
Surtees JA, Alani E.
J Mol Biol 360(3):523-36. Epub 2006 Jun 5. 2006
14MLH1, MSH3
Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression.
Plaschke J, Krüger S, Jeske B, Theissig F, Kreuz FR, Pistorius S, Saeger HD, Iaccarino I, Marra G, Schackert HK.
Cancer Res 64(3):864-70. 2004
15MSH3, MSH6
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression.
Edelmann W, Umar A, Yang K, Heyer J, Kucherlapati M, Lia M, Kneitz B, Avdievich E, Fan K, Wong E, Crouse G, Kunkel T, Lipkin M, Kolodner RD, Kucherlapati R.
Cancer Res 60(4):803-7. 2000
16MSH3
Association between single nucleotide polymorphisms in the hMSH3 gene and sporadic colon cancer with microsatellite instability.
Orimo H, Nakajima E, Yamamoto M, Ikejima M, Emi M, Shimada T.
J Hum Genet 45(4):228-30. 2000
17MSH3
Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cells.
Ceccotti S, Ciotta C, Fronza G, Dogliotti E, Bignami M.
Nucleic Acids Res 28(13):2577-84. 2000
18MLH1, MSH3
Frequent loss of heterozygosity at the DNA mismatch-repair loci hMLH1 and hMSH3 in sporadic breast cancer.
Benachenhou N, et al.
Br J Cancer 79(7-8):1012-7. 1999
19MSH3
Frameshift mutations and a length polymorphism in the hMSH3 gene and the spectrum of microsatellite instability in sporadic colon cancer.
Orimo H, Nakajima E, Ikejima M, Emi M, Shimada T.
Jpn J Cancer Res 90(12):1310-5. 1999
20MLH1, MSH3, TSG3B, TSG5B
High resolution deletion mapping reveals frequent allelic losses at the DNA mismatch repair loci hMLH1 and hMSH3 in non-small cell lung cancer.
Benachenhou N, et al.
Int J Cancer 77 : 173-180. 1998
21MSH6, MLH1, MSH2, MSH3
Allelic losses and DNA methylation at DNA mismatch repair loci in sporadic colorectal cancer.
Benachenhou N, et al.
Carcinogenesis 19 : 1925-1929. 1998
22MSH6, HNPCC2, HNPCC5, MSH3
Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas.
Yin J, Kong D, Wang S, Zou TT, Souza RF, Smolinski KN, Lynch PM, Hamilton SR, Sugimura H, Powell SM, Young J, Abraham JM, Meltzer SJ.
Hum Mutat 10(6):474-8. 1997
23MSH2, MSH3, MSH6
MutS homologs in mammalian cells.
Fishel R, Wilson T.
Curr Opin Genet Dev 7(1):105-13. Review. 1997
24MSH3
Genomic organization and expression of the human MSH3 gene.
Watanabe A, et al.
Genomics 31 : 311-318. 1996
25MSH3
Frameshift mutator mutations.
Malkhosyan S, et al.
Nature 382 : 499-500. 1996
26MSH3
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair.
Risinger JI, et al.
Nat Genet 14 : 102-105. 1996
27MSH2, MSH3, MSH6
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.
Acharya S, Wilson T, Gradia S, Kane MF, Guerrette S, Marsischky GT, Kolodner R, Fishel R.
Proc Natl Acad Sci U S A 93(24):13629-34. 1996
28MSH3
Loss of expression of the human MSH3 gene in hematological malignancies.
Inokuchi K, et al.
Biochem Biophys Res Commun 214 : 171-179. 1995
29MSH3
The yeast gene MSH3 defines a new class of eukaryotic MutS homologues.
New L, et al.
Mol Gen Genet 239 : 97-108. 1993
30MSH3
Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene.
Fujii H, et al.
J Biol Chem 264 : 10057-10064. 1989