Citations for
1FCER1A, GATA1, GATA2, MS4A2, SPI1
Critical Roles for PU.1, GATA1, and GATA2 in the expression of human FcεRI on mast cells: PU.1 and GATA1 transactivate FCER1A, and GATA2 transactivates FCER1A and MS4A2.
Inage E, Kasakura K, Yashiro T, Suzuki R, Baba Y, Nakano N, Hara M, Tanabe A, Oboki K, Matsumoto K, Saito H, Niyonsaba F, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T, Nishiyama C.
J Immunol 192(8):3936-46. doi: 10.4049/jimmunol.1302366. Epub 2014 Mar 17. 2014
2LYN, MS4A2
Highly expressed cytoplasmic FcεRIβ in human mast cells functions as a negative regulator of the FcRγ-mediated cell activation signal.
Okayama Y, Matsuda A, Kashiwakura JI, Sasaki-Sakamoto T, Nunomura S, Shimokawa T, Yamaguchi K, Takahashi S, Ra C.
Clin Exp Allergy 44(2):238-49. doi: 10.1111/cea.12210. 2014
3MS4A2
A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells.
Cruse G, Beaven MA, Ashmole I, Bradding P, Gilfillan AM, Metcalfe DD.
Immunity 38(5):906-17. doi: 10.1016/j.immuni.2013.04.007. Epub 2013 May 2. 2013
4LYN, MS4A2
The interaction between Lyn and FcεRIβ is indispensable for FcεRI-mediated human mast cell activation.
Okayama Y, Kashiwakura JI, Matsuda A, Sasaki-Sakamoto T, Nunomura S, Yokoi N, Ebihara N, Kuroda K, Ohmori K, Saito H, Ra C.
Allergy 67(10):1241-9. doi: 10.1111/j.1398-9995.2012.02879.x.. Epub 2012 Jul 30. 2012
5CCL2, HDAC2, HDAC3, MS4A2
Histone deacetylase 3 mediates allergic skin inflammation by regulating expression of MCP1 protein.
Kim Y, Kim K, Park D, Lee E, Lee H, Lee YS, Choe J, Jeoung D.
J Biol Chem 287(31):25844-59. doi: 10.1074/jbc.M112.348284. Epub 2012 Jun 7. 2012
6FCER1A, MS4A2
FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.
Nunomura S, Gon Y, Yoshimaru T, Kashiwakura J, Kawakami T, Ra C.
Eur J Immunol 40(4):1205-17. doi: 10.1002/eji.200939651. 2010
7MS4A2
Characterization of the methylation patterns of MS4A2 in atopic cases and controls.
Ferreira MA, Oates NA, van Vliet J, Zhao ZZ, Ehrich M, Martin NG, Montgomery GW, Whitelaw E, Duffy DL.
Allergy 65(3):333-7. doi: 10.1111/j.1398-9995.2009.02135.x. Epub 2009 Sep 1. 2010
8MS4A2
IgE signaling suppresses FcepsilonRIbeta expression.
Brenzovich J, Macey M, Fernando J, Chong HJ, Barnstein B, Mirmonsef P, Morales JK, Kimura A, Cruz TD, Ryan JJ.
J Leukoc Biol 86(6):1351-8. doi: 10.1189/jlb.0409231. Epub 2009 Sep 9. 2009
9MS4A2
Promoter polymorphism in the MS4A2 gene and asthma in the Indian population.
Sharma S, Ghosh B.
Int Arch Allergy Immunol 149(3):208-18. doi: 10.1159/000199716. Epub 2009 Feb 12. 2009
10FCER1A, MS4A2
Additive association between FCER1A and FCER1B genetic polymorphisms and total serum IgE levels.
Potaczek DP, Sanak M, Szczeklik A.
Allergy 62(9):1095-6. No abstract available. 2007
11MS4A2
Genetic polymorphisms at FCER1B and PAI-1 and asthma susceptibility.
Hizawa N, Maeda Y, Konno S, Fukui Y, Takahashi D, Nishimura M.
Clin Exp Allergy 36(7):872-6. Review. 2006
12MS4A2
The FcepsilonRIbeta immunoreceptor tyrosine-based activation motif exerts inhibitory control on MAPK and IkappaB kinase phosphorylation and mast cell cytokine production.
Furumoto Y, Nunomura S, Terada T, Rivera J, Ra C.
J Biol Chem 279(47):49177-87. Epub 2004 Sep 7. 2004
13MS4A2
Competing functions encoded in the allergy-associated F(c)epsilonRIbeta gene.
Donnadieu E, Jouvin MH, Rana S, Moffatt MF, Mockford EH, Cookson WO, Kinet JP.
Immunity 18(5):665-74. 2003
14MS4A1, MS4A10, MS4A12, MS4A2, MS4A3, MS4A4A, MS4A4E, MS4A5, MS4A6A, MS4A6B, MS4A6E, MS4A7, MS4A8B
Identification of a cd20-, fcepsilonribeta-, and htm4-related gene family: sixteen new ms4a family members expressed in human and mouse.
Liang Y, Tedder TF.
Genomics 72(2):119-27. 2001
15MS4A1, MS4A10, MS4A12, MS4A2, MS4A3, MS4A4A, MS4A4E, MS4A5, MS4A6A, MS4A6B, MS4A6E, MS4A7, MS4A8B
Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor.
Ishibashi K, Suzuki M, Sasaki S, Imai M.
Gene 264(1):87-93. 2001
16MS4A1, MS4A10, MS4A12, MS4A2, MS4A3, MS4A4A, MS4A4E, MS4A5, MS4A6A, MS4A6B, MS4A6E, MS4A7, MS4A8B
Structural organization of the human MS4A gene cluster on Chromosome 11q12.
Liang Y, Buckley TR, Tu L, Langdon SD, Tedder TF.
Immunogenetics 53(5):357-68. 2001
17MS4A1, MS4A2, D11S1807, D11S1808, D11S1809, D11S1810, D11S1811, D11S1812, D11S813, D11S814
A 2.8 Mb YAC contig in 11q12-q13 localizes candidate genes for atopy : FcepsilonRIbeta and CD20.
Stafford AN, et al.
Hum Mol Genet 3 : 779-785. 1994
18MS4A2
A frequent human CD20 (B1) differentiation antigen DNA polymorphism detected with Mspl is located near 11q12-13.
Charmley P, et al.
Nucleic Acids Res 18 : 207. 1990
19MS4A2
The gene that encodes the human CD20 (B1) differentiation antigen is located on chromosome 11 near the t(11;14)(q13;q32) translocation site.
Tedder TF, et al.
J Immunol 142 : 2555-2559. 1989
20MS4A2
Structure of the gene encoding the human B lymphocyte differentiation antigen CD20 (B1).
Tedder TF, et al.
J Immunol 142 : 2560-2568. 1989