| 1 | GHSR, MRAP2
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| The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a.
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| Rouault AAJ, Rosselli-Murai LK, Hernandez CC, Gimenez LE, Tall GG, Sebag JA.
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| Sci Signal. Jan 7;13(613):eaax4569. doi: 10.1126/scisignal.aax4569 2020
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| 2 | MRAP2
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| MRAP2 regulates endometrial receptivity and function.
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| D'Aurora M, Romani F, Franchi S, Diomede F, Merciaro I, Impicciatore GG, Trubiani O, Stuppia L, Tiboni GM, Gatta V.
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| Gene. Jun 30;703:7-12. doi: 10.1016/j.gene.2019.04.001. Epub 2019 Apr 3 2019
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| 3 | MRAP2
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| Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.
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| Baron M, Maillet J, Huyvaert M, Dechaume A, Boutry R, Loiselle H, Durand E, Toussaint B, Vaillant E, Philippe J, Thomas J, Ghulam A, Franc S, Charpentier G, Borys JM, Lévy-Marchal C, Tauber M, Scharfmann R, Weill J, Aubert C, Kerr-Conte J, Pattou F, Roussel R, Balkau B, Marre M, Boissel M, Derhourhi M, Gaget S, Canouil M, Froguel P, Bonnefond A.
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| Nat Med. Nov;25(11):1733-1738. doi: 10.1038/s41591-019-0622-0. Epub 2019 Nov 7 2019
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| 4 | MC4R, MRAP2
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| Melanocortin Receptor Accessory Protein 2-Induced Adrenocorticotropic Hormone Response of Human Melanocortin 4 Receptor.
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| Soletto L, Hernández-Balfagó S, Rocha A, Scheerer P, Kleinau G, Cerdá-Reverter JM.
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| J Endocr Soc. Dec 6;3(2):314-323. doi: 10.1210/js.2018-00370. eCollection 2019 Feb 1 2018
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| 5 | MRAP2
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| MRAP2 regulates ghrelin receptor signaling and hunger sensing.
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| Srisai D, Yin TC, Lee AA, Rouault AAJ, Pearson NA, Grobe JL, Sebag JA.
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| Nat Commun. Sep 28;8(1):713. doi: 10.1038/s41467-017-00747-6 2017
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| 6 | HCRTR1, MRAP2, PROKR1
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| Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling.
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| Rouault AAJ, Lee AA, Sebag JA.
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| Biochim Biophys Acta Mol Cell Res. Dec;1864(12):2322-2329. doi: 10.1016/j.bbamcr.2017.09.008. Epub 2017 Sep 20 2017
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| 7 | DEL6QP, MRAP2, SIM1
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| Copy number variation (CNV) analysis and mutation analysis of the 6q14.1-6q16.3 genes SIM1 and MRAP2 in Prader Willi like patients.
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| Geets E, Zegers D, Beckers S, Verrijken A, Massa G, Van Hoorenbeeck K, Verhulst S, Van Gaal L, Van Hul W.
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| Mol Genet Metab. Mar;117(3):383-8. doi: 10.1016/j.ymgme.2016.01.003. Epub 2016 Jan 9 2016
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| 8 | MC4R, MRAP2
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| Melanocortin receptor accessory proteins in adrenal disease and obesity.
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| Jackson DS, Ramachandrappa S, Clark AJ, Chan LF.
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| Front Neurosci. Jun 10;9:213. doi: 10.3389/fnins.2015.00213. eCollection 2015 2015
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| 9 | MRAP, MRAP2
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| Melanocortin receptor accessory proteins in adrenal gland physiology and beyond.
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| Novoselova TV, Jackson D, Campbell DC, Clark AJ, Chan LF.
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| J Endocrinol 217(1):R1-11. doi: 10.1530/JOE-12-0501. Print 2013 Apr. Review.
2013
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| 10 | MC2R, MRAP, MRAP2
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| Involvement of melanocortin receptor accessory proteins (MRAPs) in the function of melanocortin receptors.
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| Cerdá-Reverter JM, Agulleiro MJ, Cortés R, Sánchez E, Guillot R, Leal E, Fernández-Durán B, Puchol S, Eley M.
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| Gen Comp Endocrinol 188:133-6. doi: 10.1016/j.ygcen.2013.01.017. Epub 2013 Feb 11. Review.
2013
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| 11 | MRAP2
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| Mrap2: an accessory protein linked to obesity.
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| Liu T, Elmquist JK, Williams KW.
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| Cell Metab. Sep 3;18(3):309-11. doi: 10.1016/j.cmet.2013.08.016 2013
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| 12 | MC2R, MRAP, MRAP2
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| Melanocortin 2 receptor-associated protein (MRAP) and MRAP2 in human adrenocortical tissues: regulation of expression and association with ACTH responsiveness.
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| Hofland J, Delhanty PJ, Steenbergen J, Hofland LJ, van Koetsveld PM, van Nederveen FH, de Herder WW, Feelders RA, de Jong FH.
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| J Clin Endocrinol Metab 97(5):E747-54. doi: 10.1210/jc.2011-2328. Epub 2012 Mar 14.
2012
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| 13 | MC2R, MRAP, MRAP2
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| Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland.
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| Gorrigan RJ, Guasti L, King P, Clark AJ, Chan LF.
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| J Mol Endocrinol 46(3):227-32. doi: 10.1530/JME-11-0011. Print 2011 Jun.
2011
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| 14 | MC2R, MRAP, MRAP2
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| Mechanisms of melanocortin-2 receptor (MC2R) internalization and recycling in human embryonic kidney (hek) cells: identification of Key Ser/Thr (S/T) amino acids.
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| Roy S, Roy SJ, Pinard S, Taillefer LD, Rached M, Parent JL, Gallo-Payet N.
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| Mol Endocrinol 25(11):1961-77. doi: 10.1210/me.2011-0018. Epub 2011 Sep 15.
2011
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| 15 | MRAP, MRAP2
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| Regions of melanocortin 2 (MC2) receptor accessory protein necessary for dual topology and MC2 receptor trafficking and signaling.
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| Sebag JA, Hinkle PM.
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| J Biol Chem 284(1):610-8. Epub 2008 Nov 3.
2009
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| 16 | MRAP, MRAP2
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| MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.
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| Chan LF, Webb TR, Chung TT, Meimaridou E, Cooray SN, Guasti L, Chapple JP, Egertová M, Elphick MR, Cheetham ME, Metherell LA, Clark AJ.
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| Proc Natl Acad Sci U S A 106(15):6146-51. Epub 2009 Mar 27.
2009
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| 17 | MRAP, MRAP2
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| MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.
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| Chan LF, Webb TR, Chung TT, Meimaridou E, Cooray SN, Guasti L, Chapple JP, Egertová M, Elphick MR, Cheetham ME, Metherell LA, Clark AJ.
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| Proc Natl Acad Sci U S A 106(15):6146-51. doi: 10.1073/pnas.0809918106. Epub 2009 Mar 27.
2009
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