Citations for
1HDAC1, MORF4L1, PHF12, SIN3B
The chromatin associated Phf12 protein maintains nucleolar integrity and prevents premature cellular senescence.
Graveline R, Marcinkiewicz K, Choi S, Paquet M, Wurst W, Floss T, David G.
Mol Cell Biol ol Cell Biol. 2016 Dec 12. pii: MCB.00522-16. [Epub ahead of print] 2016
2MORF4L1
MRG15 is required for pre-mRNA splicing and spermatogenesis.
Iwamori N, Tominaga K, Sato T, Riehle K, Iwamori T, Ohkawa Y, Coarfa C, Ono E, Matzuk MM.
Proc Natl Acad Sci U S A 113(37):E5408-15. doi: 10.1073/pnas.1611995113. 2016
3MORF4L1, MRGBP, PHF12
Structural Basis for Multi-specificity of MRG Domains.
Xie T, Zmyslowski AM, Zhang Y, Radhakrishnan I.
Structure 23(6):1049-57. doi: 10.1016/j.str.2015.03.020. 2015
4MORF4L1
Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization.
Chen Y, Li J, Dunn S, Xiong S, Chen W, Zhao Y, Chen BB, Mallampalli RK, Zou C.
J Biol Chem 289(10):7092-8. doi: 10.1074/jbc.M113.527507. Erratum in: J Biol Chem. 2014 Sep 5;289(36):24943. 2014
5MORF4L1
Alternative splicing of the chromodomain protein Morf4l1 pre-mRNA has implications on cell differentiation in the developing chicken retina.
Boije H, Ring H, Shirazi Fard S, Grundberg I, Nilsson M, Hallböök F.
J Mol Neurosci 51(2):615-28. doi: 10.1007/s12031-013-0034-4. 2013
6MORF4L1, TMPRSS4
Maintenance of interphase chromosome compaction and homolog pairing in Drosophila is regulated by the condensin cap-h2 and its partner Mrg15.
Smith HF, Roberts MA, Nguyen HQ, Peterson M, Hartl TA, Wang XJ, Klebba JE, Rogers GC, Bosco G.
Genetics 195(1):127-46. doi: 10.1534/genetics.113.153544. 2013
7MORF4L1, PHF12
Structural basis for molecular interactions involving MRG domains: implications in chromatin biology.
Xie T, Graveline R, Kumar GS, Zhang Y, Krishnan A, David G, Radhakrishnan I.
Structure 20(1):151-60. doi: 10.1016/j.str.2011.10.019. 2012
8MORF4L1, MRGBP, VEZF1
Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II.
Gowher H, Brick K, Camerini-Otero RD, Felsenfeld G.
Proc Natl Acad Sci U S A 109(7):2370-5. doi: 10.1073/pnas.1121538109. 2012
9MORF4L1, MRFAP1, MRGBP
Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
Larance M, Kirkwood KJ, Xirodimas DP, Lundberg E, Uhlen M, Lamond AI.
Mol Cell Proteomics 11(3):M111.014407. doi: 10.1074/mcp.M111.014407. 2012
10MORF4L1
MRG15 activates the cdc2 promoter via histone acetylation in human cells.
Peña AN, Tominaga K, Pereira-Smith OM.
Exp Cell Res 317(11):1534-40. doi: 10.1016/j.yexcr.2011.02.001. Epub 2011 Feb 14. 2011
11HDAC1, MORF4L1, PHF12, SIN3B
A novel mammalian complex containing Sin3B mitigates histone acetylation and RNA polymerase II progression within transcribed loci.
Jelinic P, Pellegrino J, David G.
Mol Cell Biol 31(1):54-62. doi: 10.1128/MCB.00840-10. 2011
12MORF4L1
Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor.
Chen M, Pereira-Smith OM, Tominaga K.
Stem Cell Res 7(1):75-88. doi: 10.1016/j.scr.2011.04.002. 2011
13MORF4L1
Mutation analysis of the gene encoding the PALB2-binding protein MRG15 in BRCA1/2-negative breast cancer families.
Rio Frio T, Haanpää M, Pouchet C, Pylkäs K, Vuorela M, Tischkowitz M, Winqvist R, Foulkes WD.
J Hum Genet 55(12):842-3. Epub 2010 Sep 16. 2010
14MORF4L1, PALB2
MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.
Hayakawa T, Zhang F, Hayakawa N, Ohtani Y, Shinmyozu K, Nakayama J, Andreassen PR.
J Cell Sci 123(Pt 7):1124-30. doi: 10.1242/jcs.060178. 2010
15MORF4L1, PALB2
MRG15 is a novel PALB2-interacting factor involved in homologous recombination.
Sy SM, Huen MS, Chen J.
J Biol Chem 284(32):21127-31. Epub 2009 Jun 24.PMID: 19553677 2009
16MORF4L1
MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells.
Chen M, Takano-Maruyama M, Pereira-Smith OM, Gaufo GO, Tominaga K.
J Neurosci Res 87(7):1522-31. doi: 10.1002/jnr.21976. 2009
17KDM5A, MORF4L1
RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.
Hayakawa T, Ohtani Y, Hayakawa N, Shinmyozu K, Saito M, Ishikawa F, Nakayama J.
Genes Cells 12(6):811-26. 2007
18MORF4L1
The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging.
Pena AN, Pereira-Smith OM.
Ann N Y Acad Sci 1100:299-305. Review. 2007
19MORF4L1
Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain.
Bowman BR, Moure CM, Kirtane BM, Welschhans RL, Tominaga K, Pereira-Smith OM, Quiocho FA.
Structure 14(1):151-8. 2006
20MORF4L1
Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Zhang P, Du J, Sun B, Dong X, Xu G, Zhou J, Huang Q, Liu Q, Hao Q, Ding J.
Nucleic Acids Res 34(22):6621-8. Epub 2006 Nov 28. 2006
21MORF4L1, MRFAP1, MRGBP
Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain.
Bowman BR, Moure CM, Kirtane BM, Welschhans RL, Tominaga K, Pereira-Smith OM, Quiocho FA.
Structure 14(1):151-8. 2006
22MORF4L1, MRFAP1
The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14.
Zhang P, Zhao J, Wang B, Du J, Lu Y, Chen J, Ding J.
Protein Sci 15(10):2423-34. 2006
23MORF4L1, SET, FIGF, CCT3
Gene expression in pharyngeal arch 1 during human embryonic development.
Cai J, Ash D, Kotch LE, Jabs EW, Attie-Bitach T, Auge J, Mattei G, Etchevers H, Vekemans M, Korshunova Y, Tidwell R, Messina DN, Winston JB, Lovett M.
Hum Mol Genet 14(7):903-12. Epub 2005 Feb 9. 2005
24MORF4L1
MRG15 regulates embryonic development and cell proliferation.
Tominaga K, Kirtane B, Jackson JG, Ikeno Y, Ikeda T, Hawks C, Smith JR, Matzuk MM, Pereira-Smith OM.
Mol Cell Biol 25(8):2924-37. 2005
25MORF4L1, MORF4L2
MrgX is not essential for cell growth and development in the mouse.
Tominaga K, Matzuk MM, Pereira-Smith OM.
Mol Cell Biol 25(12):4873-80. 2005
26MORF4L1, MORF4L2, MRFAP1, MRGBP
Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.
Cai Y, Jin J, Tomomori-Sato C, Sato S, Sorokina I, Parmely TJ, Conaway RC, Conaway JW.
J Biol Chem 278(44):42733-6. 2003
27MORF4L1, PHF12, SIN3A
Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split.
Yochum GS, Ayer DE.
Mol Cell Biol 22(22):7868-76.PMID: 12391155 2002
28MORF4L1
Conservation of the MORF4 related gene family: identification of a new chromo domain subfamily and novel protein motif.
Bertram MJ, Pereira-Smith OM.
Gene 266(1-2):111-21. 2001