Citations for
1KRT24, MMP9
Relative gene expression analysis of human pterygium tissues and UV radiation-evoked gene expression patterns in corneal and conjunctival cells.
Shibata N, Ishida H, Kiyokawa E, Singh DP, Sasaki H, Kubo E.
Exp Eye Res. Oct;199:108194. doi: 10.1016/j.exer.2020.108194. Epub 2020 Aug 19. 2020
2MMP9, TIMP2
TIMP-2 inhibits metastasis and predicts prognosis of colorectal cancer via regulating MMP-9
Wang W, Li D, Xiang L, Lv M, Tao L, Ni T, Deng J, Gu X, Masatara S, Liu Y, Zhou Y.
Cell Adh Migr. Dec;13(1):273-284. doi: 10.1080/19336918.2019.1639303. 2019
3GADD45A, MMP9
GADD45a Promotes Active DNA Demethylation of the MMP-9 Promoter via Base Excision Repair Pathway in AGEs-Treated Keratinocytes and in Diabetic Male Rat Skin.
Zhou L, Wang W, Yang C, Zeng T, Hu M, Wang X, Li N, Sun K, Wang C, Zhou J, Ren M, Yan L.
Endocrinology 159(2):1172-1186. doi: 10.1210/en.2017-00686. 2018
4ADM, AGTRAP, ALOX5, ENTPD1, IRAK3, MMP9, S100A8
Identification of key pathogenic genes of sepsis based on the Gene Expression Omnibus database.
Lu X, Xue L, Sun W, Ye J, Zhu Z, Mei H.
Mol Med Rep. Feb;17(2):3042-3054. doi: 10.3892/mmr.2017.8258. Epub 2017 Dec 12 2018
5CDH2, INVS, MMP2, MMP9, VIM
Inversin correlates with the malignant phenotype of non-small cell lung cancer and promotes the invasiveness of lung cancer cells.
Jiang GY, Zhang Y, Zhang XP, Lin XY, Yu JH, Wang EH.
Tumour Biol 39(6):1010428317691177. doi: 10.1177/1010428317691177. 2017
6CA8, MMP9, PTK2
Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells.
Wang TK, Lin YM, Lo CM, Tang CH, Teng CL, Chao WT, Wu MH, Liu CS, Hsieh M.
Tumour Biol 37(6):7989-8005. doi: 10.1007/s13277-015-4661-y. Epub 2015 Dec 28. 2016
7HOXC6, MMP9
HOXC6 promotes gastric cancer cell invasion by upregulating the expression of MMP9.
Chen SW, Zhang Q, Xu ZF, Wang HP, Shi Y, Xu F, Zhang WJ, Wang P, Li Y.
Mol Med Rep 14(4):3261-8. doi: 10.3892/mmr.2016.5640. Epub 2016 Aug 19. 2016
8CTSK, MMP9
Matrix-metalloproteinase-9 is cleaved and activated by cathepsin K.
Christensen J, Shastri VP.
BMC Res Notes 8:322. doi: 10.1186/s13104-015-1284-8. 2015
9HEY1, MMP9
Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression.
Tsuru A, Setoguchi T, Matsunoshita Y, Nagao-Kitamoto H, Nagano S, Yokouchi M, Maeda S, Ishidou Y, Yamamoto T, Komiya S.
Br J Cancer 112(7):1232-40. doi: 10.1038/bjc.2015.84. 2015
10MAPK14, MMP9, PGF
Placental growth factor promotes metastases of non-small cell lung cancer through MMP9.
Zhang W, Zhang T, Lou Y, Yan B, Cui S, Jiang L, Han B.
Cell Physiol Biochem 37(3):1210-8. doi: 10.1159/000430244. Epub 2015 Sep 30. 2015
11IAPP, MMP9
Matrix Metalloproteinase-9 Protects Islets from Amyloid-induced Toxicity.
Meier DT, Tu LH, Zraika S, Hogan MF, Templin AT, Hull RL, Raleigh DP, Kahn SE.
J Biol Chem 290(51):30475-85. doi: 10.1074/jbc.M115.676692. Epub 2015 Oct 19. 2015
12ADAM12, LCN2, MMP9
Urinary ADAM12 and MMP-9/NGAL complex detect the presence of gastric cancer.
Shimura T, Dagher A, Sachdev M, Ebi M, Yamada T, Yamada T, Joh T, Moses MA.
Cancer Prev Res (Phila) 8(3):240-8. doi: 10.1158/1940-6207.CAPR-14-0229. 2015
13MMP9, PLOD3
Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation.
Dayer C, Stamenkovic I.
J Biol Chem 290(22):13763-78. doi: 10.1074/jbc.M114.622274. Epub 2015 Mar 30. 2015
14MMP9, PRKD2, VEGFA
Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases.
Wille C, Köhler C, Armacki M, Jamali A, Gössele U, Pfizenmaier K, Seufferlein T, Eiseler T.
Mol Biol Cell 25(3):324-36. doi: 10.1091/mbc.E13-06-0334. Epub 2013 Dec 11. 2014
15IL23, MMP9
Cutting Edge: MMP-9 inhibits IL-23p19 expression in dendritic cells by targeting membrane stem cell factor affecting lung IL-17 response.
Oriss TB, Krishnamoorthy N, Raundhal M, Morse C, Chakraborty K, Khare A, Huff R, Ray P, Ray A.
J Immunol 192(12):5471-5. doi: 10.4049/jimmunol.1303183. Epub 2014 May 14. 2014
16CD40LG, MMP9, RAC1
Rac1 regulates platelet shedding of CD40L in abdominal sepsis.
Hwaiz R, Rahman M, Zhang E, Thorlacius H.
Lab Invest 94(9):1054-63. doi: 10.1038/labinvest.2014.92. Epub 2014 Jul 21. 2014
17AHSG, MMP3, MMP9
Low fetuin-A level in migraine: a case-control study.
Tanriverdi MH, Varol S, Arikanoglu A, Gamze Erten Bucaktepe P, Celepkolu T, Akil E, Yuksel H, Uzar E.
Neurol Sci 35(2):271-5. doi: 10.1007/s10072-013-1504-8. Epub 2013 Aug 8. 2014
18MMP9, RNF213
Increased vascular MMP-9 in mice lacking RNF213: moyamoya disease susceptibility gene.
Sonobe S, Fujimura M, Niizuma K, Fujimura T, Furudate S, Nishijima Y, Kure S, Tominaga T.
Neuroreport 25(18):1442-6. doi: 10.1097/WNR.0000000000000289. 2014
19ADAM17, MMP9
ADAM17 Mediates MMP9 Expression in Lung Epithelial Cells.
Li YQ, Yan JP, Xu WL, Wang H, Xia YJ, Wang HJ, Zhu YY, Huang XJ.
PLoS One 8(1):e51701. doi: 10.1371/journal.pone.0051701. Epub 2013 Jan 14. 2013
20MMP2, MMP9, SPARC
The expression of SPARC in human intracranial aneurysms and its relationship with MMP-2/-9.
Li B, Li F, Chi L, Zhang L, Zhu S.
PLoS One 8(3):e58490. doi: 10.1371/journal.pone.0058490. Epub 2013 Mar 14. 2013
21FOXP3, LCK, MMP9, SKP2, VEGFA
Phosphorylation of FOXP3 by LCK downregulates MMP9 expression and represses cell invasion.
Nakahira K, Morita A, Kim NS, Yanagihara I.
PLoS One 8(10):e77099. doi: 10.1371/journal.pone.0077099. eCollection 2013. 2013
22AGT, MMP9
Important role of the angiotensin II pathway in producing matrix metalloproteinase-9 in human thoracic aortic aneurysms.
Nagasawa A, Yoshimura K, Suzuki R, Mikamo A, Yamashita O, Ikeda Y, Tsuchida M, Hamano K.
J Surg Res 183(1):472-7. doi: 10.1016/j.jss.2012.12.012. Epub 2013 Jan 1. 2013
23HDAC10, MMP2, MMP9
Histone deacetylase (HDAC) 10 suppresses cervical cancer metastasis through inhibition of matrix metalloproteinase (MMP) 2 and 9 expression.
Song C, Zhu S, Wu C, Kang J.
J Biol Chem 288(39):28021-33. doi: 10.1074/jbc.M113.498758. Epub 2013 Jul 29. 2013
24IAPP, MMP9
Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide.
Aston-Mourney K, Zraika S, Udayasankar J, Subramanian SL, Green PS, Kahn SE, Hull RL.
J Biol Chem 288(5):3553-9. doi: 10.1074/jbc.M112.438457. Epub 2012 Dec 10. 2013
25CASP3, CCND1, MMP9, NUMBL, TRAF6
Numblike regulates proliferation, apoptosis, and invasion of lung cancer cell.
Yingjie L, Jian T, Changhai Y, Jingbo L.
Tumour Biol 34(5):2773-80. doi: 10.1007/s13277-013-0835-7. Epub 2013 May 17. 2013
26MMP2, MMP9, NFATC1, SKIL, SMAD3
Cooperative involvement of NFAT and SnoN mediates transforming growth factor-β (TGF-β) induced EMT in metastatic breast cancer (MDA-MB 231) cells.
Sengupta S, Jana S, Biswas S, Mandal PK, Bhattacharyya A.
Clin Exp Metastasis 30(8):1019-31. doi: 10.1007/s10585-013-9600-y. Epub 2013 Jul 6. 2013
27MMP9
Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction.
Plaks V, Rinkenberger J, Dai J, Flannery M, Sund M, Kanasaki K, Ni W, Kalluri R, Werb Z.
Proc Natl Acad Sci U S A. Jul 2;110(27):11109-14. doi: 10.1073/pnas.1309561110. Epub 2013 Jun 17. 2013
28MMP2, MMP9
Matrix metalloproteinase-9 regulates survival of neurons in newborn hippocampus.
Murase S, McKay RD.
J Biol Chem 287(15):12184-94. doi: 10.1074/jbc.M111.297671. Epub 2012 Feb 20. 2012
29MMP9
Activity-dependent local translation of matrix metalloproteinase-9.
Dziembowska M, Milek J, Janusz A, Rejmak E, Romanowska E, Gorkiewicz T, Tiron A, Bramham CR, Kaczmarek L.
J Neurosci 32(42):14538-47. doi: 10.1523/JNEUROSCI.6028-11.2012. 2012
30MMP9
Levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 mRNAs in patients with primary hypertension or hypertension-induced atherosclerosis.
Su W, Gao F, Lu J, Wu W, Zhou G, Lu S.
J Int Med Res 40(3):986-94. 2012
31ERBB2, MMP9
MMP-9 increases HER2/neu expression and alters apoptosis levels in human mammary epithelial cells (HMEC).
Fatunmbi M, Shelton J, Aronica SM.
Breast Cancer Res Treat 135(2):519-30. doi: 10.1007/s10549-012-2191-5. Epub 2012 Aug 10. 2012
32MMP9
Functional MMP-9 polymorphisms modulate plasma MMP-9 levels in multiple sclerosis patients.
Fernandes KS, Brum DG, Palei AC, Sandrim VC, Guerreiro CT, Tanus-Santos JE, Barreira AA.
J Neuroimmunol 249(1-2):56-9. doi: 10.1016/j.jneuroim.2012.04.001. Epub 2012 May 18. 2012
33MMP9
Increased expression of matrix metalloproteinase 9 in cortical lesions from patients with focal cortical dysplasia type IIb and tuberous sclerosis complex.
Li S, Yu S, Zhang C, Shu H, Liu S, An N, Yang M, Yin Q, Yang H.
Brain Res 1453:46-55. doi: 10.1016/j.brainres.2012.03.009. Epub 2012 Mar 12. 2012
34MMP9
Matrix metalloproteinase 9/gelatinase B is required for neural crest cell migration.
Monsonego-Ornan E, Kosonovsky J, Bar A, Roth L, Fraggi-Rankis V, Simsa S, Kohl A, Sela-Donenfeld D.
Dev Biol 364(2):162-77. doi: 10.1016/j.ydbio.2012.01.028. Epub 2012 Feb 8. 2012
35MMP9, TIMP2, VIM
Immunohistochemical expression of MMP-9, TIMP-2, E-cadherin and vimentin in ameloblastomas and their implication in the local aggressive behavior of these tumors.
Florescu A, Mărgăritescu C, Simionescu CE, Stepan A.
Rom J Morphol Embryol 53(4):975-84. 2012
36BDNF, MMP9
Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder.
Yoshida T, Ishikawa M, Niitsu T, Nakazato M, Watanabe H, Shiraishi T, Shiina A, Hashimoto T, Kanahara N, Hasegawa T, Enohara M, Kimura A, Iyo M, Hashimoto K.
PLoS One 7(8):e42676. doi: 10.1371/journal.pone.0042676. Epub 2012 Aug 3. 2012
37ADAM10, AGER, MMP9
Induction of RAGE shedding by activation of G protein-coupled receptors.
Metz VV, Kojro E, Rat D, Postina R.
PLoS One 7(7):e41823. doi: 10.1371/journal.pone.0041823. Epub 2012 Jul 30. 2012
38MMP9, MXI1
Over-expression of Mxi1 represses renal epithelial tubulogenesis through the reduction of matrix metalloproteinase 9.
Song SA, Yoo KH, Ko JY, Kim BH, Yook YJ, Park JH.
Biochem Biophys Res Commun 419(3):459-65. doi: 10.1016/j.bbrc.2012.02.002. Epub 2012 Feb 8. 2012
39MMP9, MTOR, TNF
TNF-α promotes human retinal pigment epithelial (RPE) cell migration by inducing matrix metallopeptidase 9 (MMP-9) expression through activation of Akt/mTORC1 signaling.
Wang CH, Cao GF, Jiang Q, Yao J.
Biochem Biophys Res Commun 425(1):33-8. doi: 10.1016/j.bbrc.2012.07.044. Epub 2012 Jul 20. 2012
40CLU, MMP9, TNF
Clusterin induces the secretion of TNF-α and the chemotactic migration of macrophages.
Shim YJ, Kang BH, Choi BK, Park IS, Min BH.
Biochem Biophys Res Commun 422(1):200-5. doi: 10.1016/j.bbrc.2012.04.162. Epub 2012 May 7. 2012
41MMP9, NINJ1
The N-terminal ectodomain of Ninjurin1 liberated by MMP9 has chemotactic activity.
Ahn BJ, Le H, Shin MW, Bae SJ, Lee EJ, Wee HJ, Cha JH, Park JH, Lee HS, Lee HJ, Jung H, Park ZY, Park SH, Han BW, Seo JH, Lo EH, Kim KW.
Biochem Biophys Res Commun 428(4):438-44. doi: 10.1016/j.bbrc.2012.10.099. Epub 2012 Nov 7. 2012
42MMP9, SMYD3
SMYD3 promotes cancer invasion by epigenetic upregulation of the metalloproteinase MMP-9.
Cock-Rada AM, Medjkane S, Janski N, Yousfi N, Perichon M, Chaussepied M, Chluba J, Langsley G, Weitzman JB.
Cancer Res 72(3):810-20. doi: 10.1158/0008-5472.CAN-11-1052. Epub 2011 Dec 22. 2012
43MMP9, PIWIL2
Piwil2 modulates the proliferation and metastasis of colon cancer via regulation of matrix metallopeptidase 9 transcriptional activity.
Li D, Sun X, Yan D, Huang J, Luo Q, Tang H, Peng Z.
Exp Biol Med (Maywood). Oct;237(10):1231-40. doi: 10.1258/ebm.2012.011380. Epub 2012 Oct 26. 2012
44KLF8, MMP9
KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9.
Wang X, Lu H, Urvalek AM, Li T, Yu L, Lamar J, DiPersio CM, Feustel PJ, Zhao J.
Oncogene 30(16):1901-11. Epub 2010 Dec 13. 2011
45MMP3, MMP9
Matrix metalloproteinase (MMP)-3 activates MMP-9 mediated vascular smooth muscle cell migration and neointima formation in mice.
Johnson JL, Dwivedi A, Somerville M, George SJ, Newby AC.
Arterioscler Thromb Vasc Biol 31(9):e35-44. Epub 2011 Jun 30. 2011
46MMP9, NEU1
Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling.
Abdulkhalek S, Amith SR, Franchuk SL, Jayanth P, Guo M, Finlay T, Gilmour A, Guzzo C, Gee K, Beyaert R, Szewczuk MR.
J Biol Chem 286(42):36532-49. doi: 10.1074/jbc.M111.237578. Epub 2011 Aug 26. 2011
47MMP9
Influence of matrix metalloproteinase MMP-9 on dendritic spine morphology.
Michaluk P, Wawrzyniak M, Alot P, Szczot M, Wyrembek P, Mercik K, Medvedev N, Wilczek E, De Roo M, Zuschratter W, Muller D, Wilczynski GM, Mozrzymas JW, Stewart MG, Kaczmarek L, Wlodarczyk J.
J Cell Sci 124(Pt 19):3369-80. doi: 10.1242/jcs.090852. Epub 2011 Sep 6. 2011
48MMP9
Serum matrix metalloproteinase-9 (MMP-9) as a biomarker for monitoring disease progression in Duchenne muscular dystrophy (DMD).
Nadarajah VD, van Putten M, Chaouch A, Garrood P, Straub V, Lochmüller H, Ginjaar HB, Aartsma-Rus AM, van Ommen GJ, den Dunnen JT, 't Hoen PA.
Neuromuscul Disord 21(8):569-78. doi: 10.1016/j.nmd.2011.05.011. Epub 2011 Jul 2. 2011
49CREB3, MMP9
Human leucine zipper protein sLZIP induces migration and invasion of cervical cancer cells via expression of matrix metalloproteinase-9.
Kang H, Jang SW, Ko J.
J Biol Chem 286(49):42072-81. doi: 10.1074/jbc.M111.272302. Epub 2011 Oct 18. 2011
50FOSL1, MMP9
FOSL1 is integral to establishing the maternal-fetal interface.
Kent LN, Rumi MA, Kubota K, Lee DS, Soares MJ.
Mol Cell Biol 31(23):4801-13. doi: 10.1128/MCB.05780-11. Epub 2011 Sep 26. 2011
51ITGB4, MMP9
MMP9 cleavage of the β4 integrin ectodomain leads to recurrent epithelial erosions in mice.
Pal-Ghosh S, Blanco T, Tadvalkar G, Pajoohesh-Ganji A, Parthasarathy A, Zieske JD, Stepp MA.
J Cell Sci 124(Pt 15):2666-75. doi: 10.1242/jcs.085480. Epub 2011 Jul 12. 2011
52MMP9, PPARD, TGFA
AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes.
Meissner M, Berlinski B, Doll M, Hrgovic I, Laubach V, Reichenbach G, Kippenberger S, Gille J, Kaufmann R.
Exp Dermatol 20(5):425-9. doi: 10.1111/j.1600-0625.2011.01253.x. 2011
53CSF3, CXCR4, MMP9, PLG
Plasminogen regulates stromal cell-derived factor-1/CXCR4-mediated hematopoietic stem cell mobilization by activation of matrix metalloproteinase-9.
Gong Y, Fan Y, Hoover-Plow J.
Arterioscler Thromb Vasc Biol 31(9):2035-43. doi: 10.1161/ATVBAHA.111.229583. 2011
54IL17, IL17RA, MMP9
The expression of interleukin (IL)-17 and IL-17 receptor and MMP-9 in human pituitary adenomas.
Qiu L, He D, Fan X, Li Z, Liao C, Zhu Y, Wang H.
Pituitary 14(3):266-75. doi: 10.1007/s11102-011-0292-5. 2011
55MMP9
Genetic polymorphism c.1562C>T of the MMP-9 is associated with macroangiopathy in type 2 diabetes mellitus.
Wang Y, Su Y, Xu Y, Pan SH, Liu GD.
Biochem Biophys Res Commun 391(1):113-7. Epub 2009 Nov 10.PMID: 19909726 2010
56EGR1, MMP9
EGR-1 activation by EGF inhibits MMP-9 expression and lymphoma growth.
Bouchard F, Bélanger SD, Biron-Pain K, St-Pierre Y.
Blood 116(5):759-66. Epub 2010 May 14.PMID: 20472833 2010
57EGR1, MMP9
Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha.
Shin SY, Kim JH, Baker A, Lim Y, Lee YH.
Mol Cancer Res 8(4):507-19. Epub 2010 Mar 23.PMID: 20332214 2010
58CD44, EGFR, MMP9
Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides.
Dufour A, Zucker S, Sampson NS, Kuscu C, Cao J.
J Biol Chem 285(46):35944-56. Epub 2010 Sep 13. 2010
59F2, MMP9
Thrombin regulates matrix metalloproteinase-9 expression in human monocytes.
Chang CJ, Hsu LA, Ko YH, Chen PL, Chuang YT, Lin CY, Liao CH, Pang JH.
Biochem Biophys Res Commun 385(2):241-6. Epub 2009 May 18. 2009
60MAND1, MAND2, MMP13, MMP9
Mutations in MMP9 and MMP13 determine the mode of inheritance and the clinical spectrum of metaphyseal anadysplasia.
Lausch E, Keppler R, Hilbert K, Cormier-Daire V, Nikkel S, Nishimura G, Unger S, Spranger J, Superti-Furga A, Zabel B.
Am J Hum Genet 85(2):168-78. Epub 2009 Jul 16. 2009
61FOXO3, MMP13, MMP9
FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases.
Storz P, Döppler H, Copland JA, Simpson KJ, Toker A.
Mol Cell Biol 29(18):4906-17. Epub 2009 Jun 29. 2009
62DMD, MMP9
Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy.
Li H, Mittal A, Makonchuk DY, Bhatnagar S, Kumar A.
Hum Mol Genet 18(14):2584-98. Epub 2009 Apr 28. 2009
63MMP9, TIMP2
Potential role of matrix metalloproteinase-2,-9 and tissue inhibitors of metalloproteinase-1,-2 in exudative pleural effusions.
Vatansever S, Gelisgen R, Uzun H, Yurt S, Kosar F.
Clin Invest Med 32(4):E293-300.PMID: 19640333 2009
64MMP12, MMP9
MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferation.
Dwivedi A, Slater SC, George SJ.
Cardiovasc Res 81(1):178-86. Epub 2008 Oct 13. 2009
65KLF5, MMP9
Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9.
Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.
J Biol Chem 283(36):24682-9. Epub 2008 Jul 10. 2008
66MMP9, PGF
PlGF-MMP-9-expressing cells restore microcirculation and efficacy of cell therapy in aged dystrophic muscle.
Gargioli C, Coletta M, De Grandis F, Cannata SM, Cossu G.
Nat Med 14(9):973-8. Epub 2008 Jul 27. 2008
67MMP2, MMP9
Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.
Decock J, Paridaens R, Ye S.
Clin Genet 73(3):197-211. Epub 2007 Dec 29. Review. 2008
68THBS2, MMP9
A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation.
Hirose Y, Chiba K, Karasugi T, Nakajima M, Kawaguchi Y, Mikami Y, Furuichi T, Mio F, Miyake A, Miyamoto T, Ozaki K, Takahashi A, Mizuta H, Kubo T, Kimura T, Tanaka T, Toyama Y, Ikegawa S.
Am J Hum Genet 82(5):1122-9. Epub 2008 May 1. 2008
69MMP9
Inhibition of matrix metalloproteinase-9 gene expression by an isoflavone metabolite, irisolidone in U87MG human astroglioma cells.
Kim SY, Lee EJ, Woo MS, Jung JS, Hyun JW, Min SW, Kim DH, Kim HS.
Biochem Biophys Res Commun 366(2):493-9. Epub 2007 Dec 10. 2008
70MADYS1, MMP9
Increased release and activity of matrix metalloproteinase-9 in patients with mandibuloacral dysplasia type A, a rare premature ageing syndrome.
Lombardi F, Fasciglione GF, D'Apice MR, Vielle A, D'Adamo M, Sbraccia P, Marini S, Borgiani P, Coletta M, Novelli G.
Clin Genet 74(4):374-83. Epub 2008 Jun 28. 2008
71MMP9, YY1
Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons.
Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, Kaczmarek L.
J Biol Chem 283(50):35140-53. Epub 2008 Oct 21. 2008
72FOSL1, MMP9
Fra-1 and Stat3 synergistically regulate activation of human MMP-9 gene.
Song Y, Qian L, Song S, Chen L, Zhang Y, Yuan G, Zhang H, Xia Q, Hu M, Yu M, Shi M, Jiang Z, Guo N.
Mol Immunol 45(1):137-43. Epub 2007 Jun 18.PMID: 17572495 2008
73A1BG, MMP9, PARK7
Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients.
Tian M, Cui YZ, Song GH, Zong MJ, Zhou XY, Chen Y, Han JX.
BMC Cancer 8:241. 2008
74CAP1, MMP9
Adenylyl cyclase-associated protein-1/CAP1 as a biological target substrate of gelatinase B/MMP-9.
Cauwe B, Martens E, Van den Steen PE, Proost P, Van Aelst I, Blockmans D, Opdenakker G.
Exp Cell Res 314(15):2739-49. doi: 10.1016/j.yexcr.2008.07.008. Epub 2008 Jul 16. 2008
75MMP9
Studies with MMP9 gene promoter polymorphism and nonsyndromic cleft lip and palate.
Letra A, da Silva RA, Menezes R, de Souza AP, de Almeida AL, Sogayar MC, Granjeiro JM.
Am J Med Genet A 143(1):89-91. No abstract available. 2007
76ACE, ARMD1, ARMD2, ARMD3, ARMD7, ARMD8, ARMDA, ARMDC, ARMS2, CFH, CX3CR1, FBLN5, HTRA1, MMP9, SOD2, VEGFA
Progress in defining the molecular biology of age related macular degeneration.
Lotery A, Trump D.
Hum Genet 122(3-4):219-36. Epub 2007 Jul 21. No abstract available. 2007
77MMP2, MMP9
Fetal MMP2/MMP9 polymorphisms and intrauterine growth restriction risk.
Gremlich S, Nguyen D, Reymondin D, Hohlfeld P, Vial Y, Witkin SS, Gerber S.
J Reprod Immunol 74(1-2):143-51. Epub 2007 Mar 23. 2007
78MMP9, TIMP1, TWIST1
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1.
Ries C, Pitsch T, Mentele R, Zahler S, Egea V, Nagase H, Jochum M.
Biochem J 405(3):547-58. 2007
79S100A4, MMP9
S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9.
Saleem M, Kweon MH, Johnson JJ, Adhami VM, Elcheva I, Khan N, Bin Hafeez B, Bhat KM, Sarfaraz S, Reagan-Shaw S, Spiegelman VS, Setaluri V, Mukhtar H.
Proc Natl Acad Sci U S A 103(40):14825-30. Epub 2006 Sep 21. 2006
80MMP8, MMP9
Matrix metalloproteinase-8 and -9 are increased at the site of abdominal aortic aneurysm rupture.
Wilson WR, Anderton M, Schwalbe EC, Jones JL, Furness PN, Bell PR, Thompson MM.
Circulation 113(3):438-45. 2006
81KDR, IL6, MMP9
Interleukin-6 triggers human cerebral endothelial cells proliferation and migration: the role for KDR and MMP-9.
Yao JS, Zhai W, Young WL, Yang GY.
Biochem Biophys Res Commun 342(4):1396-404. Epub 2006 Feb 28. 2006
82MMP9
MMP-9 microsatellite polymorphism and susceptibility to carotid arteries atherosclerosis.
Fiotti N, Altamura N, Fisicaro M, Carraro N, Uxa L, Grassi G, Torelli L, Gobbato R, Guarnieri G, Baxter BT, Giansante C.
Arterioscler Thromb Vasc Biol 26(6):1330-6. Epub 2006 Mar 30. 2006
83MMP9
Matrix metalloproteinase-9 and autoimmune diseases.
Ram M, Sherer Y, Shoenfeld Y.
J Clin Immunol 26(4):299-307. Epub 2006 May 2. Review. 2006
84TAGLN, MMP9
Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression.
Nair RR, Solway J, Boyd DD.
J Biol Chem 281(36):26424-36. Epub 2006 Jul 10. 2006
85LETY2, MMP9
Regulation of matrix metalloproteinase-9/gelatinase B expression and activation by ovarian steroids and LEFTY-A/endometrial bleeding-associated factor in the human endometrium.
Cornet PB, Galant C, Eeckhout Y, Courtoy PJ, Marbaix E, Henriet P.
J Clin Endocrinol Metab 90(2):1001-11. Epub 2004 Nov 9. 2005
86MAP4K4, MAPK8, MMP9, SPP1
JNK1 differentially regulates osteopontin-induced nuclear factor-inducing kinase/MEKK1-dependent activating protein-1-mediated promatrix metalloproteinase-9 activation.
Rangaswami H, Bulbule A, Kundu GC.
J Biol Chem 280(19):19381-92. Epub 2005 Mar 9. 2005
87MMP9,NCL
Role of nucleolin in posttranscriptional control of MMP-9 expression.
Fahling M, Steege A, Perlewitz A, Nafz B, Mrowka R, Persson PB, Thiele BJ.
Biochim Biophys Acta 1731(1):32-40. Epub 2005 Aug 29. 2005
88MMP2, MMP9
Functional basis for the overlap in ligand interactions and substrate specificities of matrix metalloproteinases-9 and -2.
Xu X, Chen Z, Wang Y, Yamada Y, Steffensen B.
Biochem J 392(Pt 1):127-34. 2005
89MMP9
MMP-9 microsatellite polymorphism and susceptibility to exudative form of age-related macular degeneration.
Fiotti N, Pedio M, Battaglia Parodi M, Altamura N, Uxa L, Guarnieri G, Giansante C, Ravalico G.
Genet Med 7(4):272-7. 2005
90MMP8, MMP9
Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD.
Vernooy JH, Lindeman JH, Jacobs JA, Hanemaaijer R, Wouters EF.
Chest 126(6):1802-10. 2004
91MMP1, MMP10, MMP11, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP2, MMP20, MMP21, MMP23A, MMP23B, MMP24, MMP25, MMP26, MMP27, MMP28, MMP3, MMP7, MMP8, MMP9
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry.
Visse R, Nagase H.
Circ Res 92(8):827-39. Review. 2003
92MMP2, MMP9
Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura.
Edwards JG, McLaren J, Jones JL, Waller DA, O'Byrne KJ.
Br J Cancer 88(10):1553-9. 2003
93MMP1, MMP9
Stromal expression of invasion-promoting, matrix-degrading proteases MMP-1 and -9 and the Ets 1 transcription factor in HNPCC carcinomas and sporadic colorectal cancers.
Behrens P, Mathiak M, Mangold E, Kirdorf S, Wellmann A, Fogt F, Rothe M, Florin A, Wernert N.
Int J Cancer 107(2):183-8. 2003
94MMP9
The role of matrix metalloproteinase-9 in dementia.
Helbecque N, Hermant X, Cottel D, Amouyel P.
Neurosci Lett 350(3):181-3. 2003
95GRP, MMP9
Expression of matrix metalloproteinase-9 and bombesin/gastrin-releasing peptide in human prostate cancers and their lymph node metastases.
Ishimaru H, Kageyama Y, Hayashi T, Nemoto T, Eishi Y, Kihara K.
Acta Oncol 41(3):289-96. 2002
96MMP9, NRG1
Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells
Yao J, Xiong S, Klos K, Nguyen N, Grijalva R, Li P, Yu D.
Oncogene 20(56):8066-74. 2001
97MMP2, MMP9
Expression of matrix metalloproteinases in the muscle of patients with inflammatory myopathies.
Choi YC, Dalakas MC.
Neurology 54(1):65-71. 2000
98MMP1, MMP9, PLAUR
Differing expression of MMPs-1 and -9 and urokinase receptor between diffuse- and intestinal-type gastric carcinoma.
Migita T, et al.
Int J Cancer 84(1):74-9. 1999
99MMP2, MMP9
Expression of matrix metalloproteinases 2 and 9 in regenerating skeletal muscle: a study in experimentally injured and mdx muscles.
Kherif S, et al.
Dev Biol 205(1):158-70. 1999
100MMP2, MMP9, MMP14
Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas.
Forsyth PA, et al.
Br J Cancer 79(11-12):1828-35. 1999
101MMP9
Involvement of the 92-kDa gelatinase (matrix metalloproteinase-9) in the ceramide-mediated inhibition of human keratinocyte growth.
Buisson-Legendre N, et al.
Biochem Biophys Res Commun 260(3):634-40 1999
102MMP9
Human mast cells produce matrix metalloproteinase 9.
Kanbe N, Tanaka A, Kanbe M, Itakura A, Kurosawa M, Matsuda H.
Eur J Immunol 29(8):2645-9 1999
103MMP9
Genetic variation at the matrix metalloproteinase-9 locus on chromosome 20q12.2-13.1.
Zhang B, Henney A, Eriksson P, Hamsten A, Watkins H, Ye S.
Hum Genet 105(5):418-23 1999
104MMP9
Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis.
Zhang B, Ye S, Herrmann SM, Eriksson P, de Maat M, Evans A, Arveiler D, Luc G, Cambien F, Hamsten A, Watkins H, Henney AM.
Circulation 99(14):1788-94 1999
105IL6, MMP9, TIMP1
Interleukin-6 regulation of matrix metalloproteinase (MMP-2 and MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) expression in malignant non-Hodgkin's lymphomas.
Kossakowska AE, Edwards DR, Prusinkiewicz C, Zhang MC, Guo D, Urbanski SJ, Grogan T, Marquez LA, Janowska-Wieczorek A.
Blood 94(6):2080-9 1999
106MMP1, MMP2, MMP9
Matrix metalloproteinase levels are elevated in inflammatory bowel disease.
Baugh MD, Perry MJ, Hollander AP, Davies DR, Cross SS, Lobo AJ, Taylor CJ, Evans GS.
Gastroenterology 117(4):814-22 1999
107MMP2, MMP9
Expression of basement membrane antigens and matrix metalloproteinases 2 and 9 in cutaneous basal and squamous cell carcinomas.
Dumas V, Kanitakis J, Charvat S, Euvrard S, Faure M, Claudy A.
Anticancer Res 19(4B):2929-38. 1999
108MMP9
MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes.
Vu TH, et al.
Cell 93 : 411-422. 1998
109MMP9
Human B lymphocytes synthesize the 92-kDa gelatinase, matrix metalloproteinase-9.
Trocme C, et al.
J Biol Chem 273 : 20677-20684. 1998
110MMP2, MMP9
Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy.
Parsons SL, et al.
Br J Cancer 78 : 1495-1502. 1998
111MMP7, MMP9
Angiostatin-converting enzyme activities of human matrilysin (MMP-7) and gelatinase B/type IV collagenase (MMP-9).
Patterson BC, Sang QA.
J Biol Chem 272(46):28823-5. 1997
112MMP9
Reassignment of the 92-kDa type IV collagenase gene (CLG4B) to human chromosome 20.
Linn R, et al.
Cytogenet Cell Genet 72 : 159-161. 1996
113MMP9
Characterization of a dinucleotide repeat in the 92 kDa type IV collagenase gene (CLG4B), localization of CLG4B to chromosome 20 and the role of CLG4B in aortic aneurysmal disease.
St Jean PL, et al.
Ann Hum Genet 59 : 17-24. 1995
114MMP9
A 25 kDa alpha 2-microglobulin-related protein is a component of the 125 kDa form of human gelatinase.
Triebel S, Bläser J, Reinke H, Tschesche H.
FEBS Lett 314(3):386-8. 1992
115MMP2, MMP9
On the structure and chromosome location of the 72- and 92-kDa human type IV collagenase genes.
Collier IE, et al.
Genomics 9 : 429-434. 1991