1 | CTNNB1, MMP7
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| Matrilysin (MMP-7) catalytic activity regulates β-catenin localization and signaling activation in lung epithelial cells.
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| Rims CR, McGuire JK.
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| Exp Lung Res 40(3):126-36. doi: 10.3109/01902148.2014.890681. 2014
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2 | MMP7
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| Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation.
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| Vandenbroucke RE, Vanlaere I, Van Hauwermeiren F, Van Wonterghem E, Wilson C, Libert C.
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| Mucosal Immunol 7(3):579-88. doi: 10.1038/mi.2013.76. Epub 2013 Oct 16.
2014
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3 | MMP7
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| Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells.
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| Gharib SA, Altemeier WA, Van Winkle LS, Plopper CG, Schlesinger SY, Buell CA, Brauer R, Lee V, Parks WC, Chen P.
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| Am J Respir Cell Mol Biol 48(3):390-6. doi: 10.1165/rcmb.2012-0083OC. Epub 2012 Dec 20.
2013
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4 | ETV1, MMP7
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| ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.
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| Shin S, Oh S, An S, Janknecht R.
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| Oncol Rep 29(1):306-14. doi: 10.3892/or.2012.2079. Epub 2012 Oct 16.
2013
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5 | MMP7, MSLN
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| Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways.
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| Chang MC, Chen CA, Chen PJ, Chiang YC, Chen YL, Mao TL, Lin HW, Lin Chiang WH, Cheng WF.
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| Biochem J 442(2):293-302. doi: 10.1042/BJ20110282.
2012
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6 | EPCAM, MMP7
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| MMP7 is a target of the tumour-associated antigen EpCAM.
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| Denzel S, Mack B, Eggert C, Massoner P, Stöcklein N, Kemming D, Harréus U, Gires O.
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| Int J Exp Pathol 93(5):341-53. doi: 10.1111/j.1365-2613.2012.00826.x.
2012
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7 | FOXC1, MMP7
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| The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression.
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| Sizemore ST, Keri RA.
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| J Biol Chem 287(29):24631-40. doi: 10.1074/jbc.M112.375865. Epub 2012 May 29.
2012
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8 | MMP7, SOX18
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| The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells.
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| Hoeth M, Niederleithner H, Hofer-Warbinek R, Bilban M, Mayer H, Resch U, Lemberger C, Wagner O, Hofer E, Petzelbauer P, de Martin R.
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| PLoS One 7(1):e30982. doi: 10.1371/journal.pone.0030982. Epub 2012 Jan 23.
2012
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9 | BMP7, MMP7
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| Matrilysin (MMP-7) inhibition of BMP-7 induced renal tubular branching morphogenesis suggests a role in the pathogenesis of human renal dysplasia.
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| McGuire JK, Harju-Baker S, Rims C, Sheen JH, Liapis H.
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| J Histochem Cytochem 60(3):243-53. doi: 10.1369/0022155411435152. Epub 2012 Jan 3.
2012
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10 | MMP7, STAT3
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| Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
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| Fukuda A, Wang SC, Morris JP 4th, Folias AE, Liou A, Kim GE, Akira S, Boucher KM, Firpo MA, Mulvihill SJ, Hebrok M.
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| Cancer Cell 19(4):441-55. doi: 10.1016/j.ccr.2011.03.002.
2011
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11 | MMP7
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| MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle cell apoptosis.
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| Williams H, Johnson JL, Jackson CL, White SJ, George SJ.
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| Cardiovasc Res 87(1):137-46. doi: 10.1093/cvr/cvq042. Epub 2010 Feb 5.
2010
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12 | MMP7
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| A novel nonsynonymous variant of matrix metalloproteinase-7 confers risk of liver cirrhosis.
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| Hung TM, Chang SC, Yu WH, Wang YW, Huang C, Lu SC, Lee PH, Chang MF.
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| Hepatology 50(4):1184-93.
2009
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13 | MMP7
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| Control of promatrilysin (MMP7) activation and substrate-specific activity by sulfated glycosaminoglycans.
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| Ra HJ, Harju-Baker S, Zhang F, Linhardt RJ, Wilson CL, Parks WC.
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| J Biol Chem 284(41):27924-32. Epub 2009 Aug 4.
2009
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14 | MMP7
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| Cellular senescence of human mammary epithelial cells (HMEC) is associated with an altered MMP-7/HB-EGF signaling and increased formation of elastin-like structures.
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| Bertram C, Hass R.
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| Mech Ageing Dev 130(10):657-69. Epub 2009 Aug 12.
2009
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15 | MMP7
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| CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer.
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| Okayama H, Kumamoto K, Saitou K, Hayase S, Kofunato Y, Sato Y, Miyamoto K, Nakamura I, Ohki S, Sekikawa K, Takenoshita S.
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| Oncol Rep 22(4):745-55.
2009
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16 | MMP7
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| MMP7 expression regulated by endocrine therapy in ERbeta-positive colon cancer cells.
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| Fang YJ, Pan ZZ, Li LR, Lu ZH, Zhang LY, Wan DS.
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| J Exp Clin Cancer Res 28:132.
2009
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17 | LAMB3, LAMC2, MMP7
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| Overexpression of beta3/gamma2 chains of laminin-5 and MMP7 in biliary cancer.
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| Oka T, Yamamoto H, Sasaki S, Ii M, Hizaki K, Taniguchi H, Adachi Y, Imai K, Shinomura Y.
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| World J Gastroenterol 15(31):3865-73. 2009
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18 | MMP7
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| Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer.
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| Fang YJ, Lu ZH, Wang GQ, Pan ZZ, Zhou ZW, Yun JP, Zhang MF, Wan DS.
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| Int J Colorectal Dis 24(8):875-84. Epub 2009 May 7.
2009
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19 | MMP7
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| Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
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| Zhao C, Bu X, Zhang N, Wang W.
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| BMC Cancer 9:224.
2009
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20 | MMP7
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| Expression of MMP-7, MMP-9, TIMP-1 and TIMP-2 mRNA in lung tissue of patients with non-small cell lung cancer (NSCLC) and benign pulmonary disease.
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| Safranek J, Pesta M, Holubec L, Kulda V, Dreslerova J, Vrzalova J, Topolcan O, Pesek M, Finek J, Treska V.
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| Anticancer Res 29(7):2513-7.
2009
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21 | MMP7
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| Transforming growth factor-B1 and matrix metalloproteinase-7 promoter variants induce risk for Helicobacter pylori-associated gastric precancerous lesions.
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| Achyut BR, Ghoshal UC, Moorchung N, Mittal B.
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| DNA Cell Biol 28(6):295-301.
2009
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22 | MMP7, SDC2
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| Syndecan-2 functions as a docking receptor for pro-matrix metalloproteinase-7 in human colon cancer cells.
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| Ryu HY, Lee J, Yang S, Park H, Choi S, Jung KC, Lee ST, Seong JK, Han IO, Oh ES.
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| J Biol Chem 284(51):35692-701. Epub .PMID: 19858218 2009
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23 | HAS3, MMP7
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| Inhibition of hyaluronan synthases decreases matrix metalloproteinase-7 (MMP-7) expression and activity.
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| Dunn KM, Lee PK, Wilson CM, Iida J, Wasiluk KR, Hugger M, McCarthy JB.
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| Surgery 145(3):322-9. doi: 10.1016/j.surg.2008.11.008.
2009
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24 | MMP7
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| Identification of amino acid residues of matrix metalloproteinase-7 essential for binding to cholesterol sulfate.
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| Higashi S, Oeda M, Yamamoto K, Miyazaki K.
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| J Biol Chem 283(51):35735-44. Epub 2008 Oct 27.
2008
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25 | MMP7
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| Endothelium specific matrilysin (MMP-7) expression in human cancers.
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| Sier CF, Hawinkels LJ, Zijlmans HJ, Zuidwijk K, de Jonge-Muller ES, Ferreira V, Hanemaaijer R, Mulder-Stapel AA, Kenter GG, Verspaget HW, Gorter A.
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| Matrix Biol 27(3):267-71. Epub 2007 Oct 26.PMID: 18023162 2008
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26 | MMP7
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| Matrix metalloproteinase-7 modulates synaptic vesicle recycling and induces atrophy of neuronal synapses.
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| Szklarczyk A, Conant K, Owens DF, Ravin R, McKay RD, Gerfen C.
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| Neuroscience 149(1):87-98. Epub 2007 Jul 28.PMID: 17826919 2007
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27 | FN1, POU5F1, MMP7, EGR1, AFP, IRX1, NR6A1
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| Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures.
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| Juric D, Sale S, Hromas RA, Yu R, Wang Y, Duran GE, Tibshirani R, Einhorn LH, Sikic BI.
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| Proc Natl Acad Sci U S A 102(49):17763-8. Epub 2005 Nov 23. 2005
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28 | MMP7
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| The functional polymorphism in the matrix metalloproteinase-7 promoter increases susceptibility to esophageal squamous cell carcinoma, gastric cardiac adenocarcinoma and non-small cell lung carcinoma.
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| Zhang J, Jin X, Fang S, Wang R, Li Y, Wang N, Guo W, Wang Y, Wen D, Wei L, Dong Z, Kuang G.
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| Carcinogenesis 26(10):1748-53. Epub 2005 Jun 1. 2005
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29 | MMP7, ADAM28
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| ADAM28 is activated by MMP-7 (matrilysin-1) and cleaves insulin-like growth factor binding protein-3.
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| Mochizuki S, Shimoda M, Shiomi T, Fujii Y, Okada Y.
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| Biochem Biophys Res Commun 315(1):79-84. 2004
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30 | MMP1, MMP10, MMP11, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP2, MMP20, MMP21, MMP23A, MMP23B, MMP24, MMP25, MMP26, MMP27, MMP28, MMP3, MMP7, MMP8, MMP9
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| Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry.
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| Visse R, Nagase H.
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| Circ Res 92(8):827-39. Review. 2003
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31 | MMP7
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| Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans.
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| Zuo F, Kaminski N, Eugui E, Allard J, Yakhini Z, Ben-Dor A, Lollini L, Morris D, Kim Y, DeLustro B, Sheppard D, Pardo A, Selman M, Heller RA.
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| Proc Natl Acad Sci U S A 99(9):6292-7. 2002
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32 | MMP7
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| Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas.
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| Masaki T, Matsuoka H, Sugiyama M, Abe N, Goto A, Sakamoto A, Atomi Y.
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| Br J Cancer 84(10):1317-21. 2001
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33 | MMP7
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| Involvement of the Ets-1 gene in overexpression of matrilysin in human hepatocellular carcinoma.
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| Ozaki I, Mizuta T, Zhao G, Yotsumoto H, Hara T, Kajihara S, Hisatomi A, Sakai T, Yamamoto K.
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| Cancer Res 60(22):6519-25. 2000
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34 | DEFA5, MMP7
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| Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense.
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| Wilson CL, et al.
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| Science 286(5437):113-7 1999
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35 | MMP7
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| Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers.
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| Adachi Y, et al.
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| Gut 45(2):252-8 1999
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36 | MMP7
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| beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer.
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| Brabletz T, Jung A, Dag S, Hlubek F, Kirchner T.
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| Am J Pathol 155(4):1033-8 1999
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37 | MMP12, MMP7
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| Accumulation of matrilysin (MMP-7) and macrophage metalloelastase (MMP-12) in actinic damage.
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| Saarialho-Kere U, Kerkela E, Jeskanen L, Hasan T, Pierce R, Starcher B, Raudasoja R, Ranki A, Oikarinen A, Vaalamo M.
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| J Invest Dermatol 113(4):664-72. 1999
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38 | MMP7
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| Enhanced production and activation of matrix metalloproteinase-7 (matrilysin) in human endometrial carcinomas.
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| Ueno H, Yamashita K, Azumano I, Inoue M, Okada Y.
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| Int J Cancer 84(5):470-7. 1999
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39 | MMP7, MMP9
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| Angiostatin-converting enzyme activities of human matrilysin (MMP-7) and gelatinase B/type IV collagenase (MMP-9).
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| Patterson BC, Sang QA.
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| J Biol Chem 272(46):28823-5. 1997
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40 | MMP7
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| Mapping of the metalloproteinase gene matrilysin (MMP7) to human chromosome 11q21-q22.
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| Knox JD, et al.
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| Cytogenet Cell Genet 72 : 179-182. 1996
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