| 1 | MMP13, MMP20, MMP8
|
| MMP13 Contributes to Dental Caries Associated with Developmental Defects of Enamel.
|
| Vasconcelos KR, Arid J, Evangelista S, Oliveira S, Dutra AL, Silva LAB, Segato RAB, Vieira AR, Nelson-Filho P, Küchler EC
|
| Caries Res. 53(4):441-446. doi: 10.1159/000496372. Epub 2019 Feb 13. 2019
|
| 2 | CALU, FBLN1, MMP13
|
| Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis.
|
| Wang Q, Shen B, Chen L, Zheng P, Feng H, Hao Q, Liu X, Liu L, Xu S, Chen J, Teng J.
|
| Oncogene 34(8):1006-18. doi: 10.1038/onc.2014.52. Epub 2014 Mar 17.
2015
|
| 3 | IL32, MMP13
|
| Interleukin-32 stimulates osteosarcoma cell invasion and motility via AKT pathway-mediated MMP-13 expression.
|
| Zhou Y, Hu Z, Li N, Jiang R.
|
| Int J Mol Med 35(6):1729-33. doi: 10.3892/ijmm.2015.2159. Epub 2015 Mar 31.
2015
|
| 4 | DKK1, GDF5, MMP13
|
| GDF5 reduces MMP13 expression in human chondrocytes via DKK1 mediated canonical Wnt signaling inhibition.
|
| Enochson L, Stenberg J, Brittberg M, Lindahl A.
|
| Osteoarthritis Cartilage steoarthritis Cartilage. 2014 Feb 19. pii: S1063-4584(14)00043-0. doi: 10.1016/j.joca.2014.02.004. [Epub ahead of print]
2014
|
| 5 | ANKRD1, MMP13
|
| ANKRD1 acts as a transcriptional repressor of MMP13 via the AP-1 site.
|
| Almodóvar-García K, Kwon M, Samaras SE, Davidson JM.
|
| Mol Cell Biol 34(8):1500-11. doi: 10.1128/MCB.01357-13. Epub 2014 Feb 10.
2014
|
| 6 | ACAN, IL6, MMP13
|
| Interleukin 6 mediates selected effects of Notch in chondrocytes.
|
| Zanotti S, Canalis E.
|
| Osteoarthritis Cartilage 21(11):1766-73. doi: 10.1016/j.joca.2013.08.010. Epub 2013 Aug 14.
2013
|
| 7 | ADGRG2, MMP13, PGF
|
| G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1.
|
| Richter GH, Fasan A, Hauer K, Grunewald TG, Berns C, Rössler S, Naumann I, Staege MS, Fulda S, Esposito I, Burdach S.
|
| J Pathol 230(1):70-81. doi: 10.1002/path.4170. Epub 2013 Mar 14.
2013
|
| 8 | CEBPB, EPAS1, MMP13, RUNX2
|
| C/EBPB and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2á as the inducer in chondrocytes.
|
| Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, Kawaguchi H.
|
| Hum Mol Genet 21(5):1111-23. doi: 10.1093/hmg/ddr540. Epub 2011 Nov 17. 2012
|
| 9 | MMP13, RUNX2, SP7
|
| Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification.
|
| Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T.
|
| J Biol Chem 287(40):33179-90. Epub 2012 Aug 6.
2012
|
| 10 | MMP13
|
| MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability.
|
| Toriseva M, Laato M, Carpén O, Ruohonen ST, Savontaus E, Inada M, Krane SM, Kähäri VM.
|
| PLoS One 7(8):e42596. doi: 10.1371/journal.pone.0042596. Epub 2012 Aug 7.
2012
|
| 11 | MMP13
|
| Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis.
|
| Kudo Y, Iizuka S, Yoshida M, Tsunematsu T, Kondo T, Subarnbhesaj A, Deraz EM, Siriwardena SB, Tahara H, Ishimaru N, Ogawa I, Takata T.
|
| J Biol Chem 287(46):38716-28. doi: 10.1074/jbc.M112.373159. Epub 2012 Sep 19.
2012
|
| 12 | MMP13
|
| Matrix metalloproteinase 13 genotype in rs640198 polymorphism is associated with severe coronary artery disease.
|
| Vaků A, Meluzín J, Blahák J, Kincl V, Goldbergová MP, Sitar J, Zlámal F, Bienertová-Vaků J, Vítovec J.
|
| Dis Markers 33(1):43-9. doi: 10.3233/DMA-2012-0902.
2012
|
| 13 | MMP13
|
| Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance.
|
| Tang SY, Herber RP, Ho SP, Alliston T.
|
| J Bone Miner Res 27(9):1936-50. doi: 10.1002/jbmr.1646.
2012
|
| 14 | ELF3, MMP13
|
| E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.
|
| Otero M, Plumb DA, Tsuchimochi K, Dragomir CL, Hashimoto K, Peng H, Olivotto E, Bevilacqua M, Tan L, Yang Z, Zhan Y, Oettgen P, Li Y, Marcu KB, Goldring MB.
|
| J Biol Chem 287(5):3559-72. doi: 10.1074/jbc.M111.265744. Epub 2011 Dec 9.
2012
|
| 15 | MMP13, ROR2, WNT5A
|
| Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression.
|
| Yamagata K, Li X, Ikegaki S, Oneyama C, Okada M, Nishita M, Minami Y.
|
| J Biol Chem 287(2):1588-99. doi: 10.1074/jbc.M111.315127. Epub 2011 Nov 28.
2012
|
| 16 | MMP13, SP7
|
| Matrix metalloproteinase 13 (MMP13) is a direct target of osteoblast-specific transcription factor osterix (Osx) in osteoblasts.
|
| Zhang C, Tang W, Li Y.
|
| PLoS One 7(11):e50525. doi: 10.1371/journal.pone.0050525. Epub 2012 Nov 21. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/a5ac9 2012
|
| 17 | MAPK14, MMP13, S100A12
|
| Role of S100A12 in the pathogenesis of osteoarthritis.
|
| Nakashima M, Sakai T, Hiraiwa H, Hamada T, Omachi T, Ono Y, Inukai N, Ishizuka S, Matsukawa T, Oda T, Takamatsu A, Yamashita S, Ishiguro N.
|
| Biochem Biophys Res Commun 422(3):508-14. doi: 10.1016/j.bbrc.2012.05.036. Epub 2012 May 16.
2012
|
| 18 | MMP13
|
| MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.
|
| Pivetta E, Scapolan M, Pecolo M, Wassermann B, Abu-Rumeileh I, Balestreri L, Borsatti E, Tripodo C, Colombatti A, Spessotto P.
|
| Breast Cancer Res 13(5):R105. doi: 10.1186/bcr3047.
2011
|
| 19 | CCN3, MMP13
|
| CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrin-dependent pathway.
|
| Tzeng HE, Chen JC, Tsai CH, Kuo CC, Hsu HC, Hwang WL, Fong YC, Tang CH.
|
| J Cell Physiol 226(12):3181-9. doi: 10.1002/jcp.22672. 2011
|
| 20 | IL6, MMP13
|
| IL-6 increases MMP-13 expression and motility in human chondrosarcoma cells.
|
| Tang CH, Chen CF, Chen WM, Fong YC.
|
| J Biol Chem 286(13):11056-66. doi: 10.1074/jbc.M110.204081. Epub 2011 Jan 28.
2011
|
| 21 | MAF, MMP13
|
| Transcriptional activation of human MMP-13 gene expression by c-Maf in osteoarthritic chondrocyte.
|
| Li T, Xiao J, Wu Z, Qiu G, Ding Y.
|
| Connect Tissue Res 51(1):48-54.
2010
|
| 22 | HDAC4, MMP13
|
| HDAC4 represses matrix metalloproteinase-13 transcription in osteoblastic cells, and parathyroid hormone controls this repression.
|
| Shimizu E, Selvamurugan N, Westendorf JJ, Olson EN, Partridge NC.
|
| J Biol Chem 285(13):9616-26. doi: 10.1074/jbc.M109.094862. Epub 2010 Jan 22.
2010
|
| 23 | MMP13
|
| MMP13 is a potential prognostic marker for colorectal cancer.
|
| Huang MY, Chang HJ, Chung FY, Yang MJ, Yang YH, Wang JY, Lin SR.
|
| Oncol Rep 24(5):1241-7.
2010
|
| 24 | MMP13
|
| MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.
|
| Meierjohann S, Hufnagel A, Wende E, Kleinschmidt MA, Wolf K, Friedl P, Gaubatz S, Schartl M.
|
| Mol Cancer 9:201. doi: 10.1186/1476-4598-9-201.
2010
|
| 25 | MMP13
|
| Evidence for the role of matrix metalloproteinase-13 in bone resorption by giant cell tumor of bone.
|
| Mak IW, Seidlitz EP, Cowan RW, Turcotte RE, Popovic S, Wu WC, Singh G, Ghert M.
|
| Hum Pathol 41(9):1320-9. doi: 10.1016/j.humpath.2010.03.001. Epub 2010 Jun 22.
2010
|
| 26 | MMP13, PTH, RUNX2
|
| Identification and characterization of Runx2 phosphorylation sites involved in matrix metalloproteinase-13 promoter activation.
|
| Selvamurugan N, Shimizu E, Lee M, Liu T, Li H, Partridge NC.
|
| FEBS Lett 583(7):1141-6. Epub 2009 Mar 3.
2009
|
| 27 | MAND1, MAND2, MMP13, MMP9
|
| Mutations in MMP9 and MMP13 determine the mode of inheritance and the clinical spectrum of metaphyseal anadysplasia.
|
| Lausch E, Keppler R, Hilbert K, Cormier-Daire V, Nikkel S, Nishimura G, Unger S, Spranger J, Superti-Furga A, Zabel B.
|
| Am J Hum Genet 85(2):168-78. Epub 2009 Jul 16.
2009
|
| 28 | FOXO3, MMP13, MMP9
|
| FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases.
|
| Storz P, Döppler H, Copland JA, Simpson KJ, Toker A.
|
| Mol Cell Biol 29(18):4906-17. Epub 2009 Jun 29. 2009
|
| 29 | MMP13
|
| MMP-13 is over-expressed in renal cell carcinoma bone metastasis and is induced by TGF-beta1.
|
| Kominsky SL, Doucet M, Thorpe M, Weber KL.
|
| Clin Exp Metastasis 25(8):865-70. Epub 2008 Aug 16.
2008
|
| 30 | MMP13
|
| Joint diseases and matrix metalloproteinases: a role for MMP-13.
|
| Takaishi H, Kimura T, Dalal S, Okada Y, D'Armiento J.
|
| Curr Pharm Biotechnol 9(1):47-54. Review.
2008
|
| 31 | MMP13
|
| ctivation of Smad signaling enhances collagenase-3 (MMP-13) expression and invasion of head and neck squamous carcinoma cells.
|
| Leivonen SK, Ala-Aho R, Koli K, Grnman R, Peltonen J, Khri VM.
|
| Oncogene 25(18):2588-600. 2006
|
| 32 | SEMD2, MMP13
|
| MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD(MO).
|
| Kennedy AM, Inada M, Krane SM, Christie PT, Harding B, Lopez-Otin C, Sanchez LM, Pannett AA, Dearlove A, Hartley C, Byrne MH, Reed AA, Nesbit MA, Whyte MP, Thakker RV.
|
| J Clin Invest 115(10):2832-42. 2005
|
| 33 | GADD45B,MMP13
|
| A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation.
|
| Ijiri K, Zerbini LF, Peng H, Correa RG, Lu B, Walsh N, Zhao Y, Taniguchi N, Huang XL, Otu H, Wang H, Wang JF, Komiya S, Ducy P, Rahman MU, Flavell RA, Gravallese EM, Oettgen P, Libermann TA, Goldring MB.
|
| J Biol Chem 280(46):38544-55. Epub 2005 Sep 2. 2005
|
| 34 | SEMD2, MMP13
|
| Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification.
|
| Inada M, Wang Y, Byrne MH, Rahman MU, Miyaura C, Lopez-Otin C, Krane SM.
|
| Proc Natl Acad Sci U S A 101(49):17192-7. Epub 2004 Dec 7. 2004
|
| 35 | MMP1, MMP10, MMP11, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP2, MMP20, MMP21, MMP23A, MMP23B, MMP24, MMP25, MMP26, MMP27, MMP28, MMP3, MMP7, MMP8, MMP9
|
| Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry.
|
| Visse R, Nagase H.
|
| Circ Res 92(8):827-39. Review. 2003
|
| 36 | MMP13
|
| The structure, regulation, and function of human matrix metalloproteinase-13.
|
| Leeman MF, Curran S, Murray GI.
|
| Crit Rev Biochem Mol Biol 37(3):149-66. Review. 2002
|
| 37 | MMP13
|
| IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways.
|
| Mengshol JA, Vincenti MP, Brinckerhoff CE.
|
| Nucleic Acids Res 29(21):4361-72. 2001
|
| 38 | MMP13
|
| Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.
|
| Johansson N, et al.
|
| Am J Pathol 154(2):469-80. 1999
|
| 39 | MMP13
|
| Characterization of collagenase 3 (matrix metalloproteinase 13) messenger RNA expression in the synovial membrane and synovial fibroblasts of patients with rheumatoid arthritis.
|
| Westhoff CS, et al.
|
| Arthritis Rheum 42(7):1517-27 1999
|
| 40 | MMP13
|
| Expression of collagenase-3 (MMP-13) in human abdominal aortic aneurysms and vascular smooth muscle cells in culture.
|
| Mao D, Lee JK, VanVickle SJ, Thompson RW.
|
| Biochem Biophys Res Commun 261(3):904-10 1999
|
| 41 | FGF2, MMP13
|
| Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor.
|
| Uria JA, et al.
|
| Am J Pathol 153 : 91-101. 1998
|
| 42 | MMP13
|
| Matrix metalloproteinase digestion of aggrecan in human cartilage tumours.
|
| Toriyama M, et al.
|
| Eur J Cancer 34 : 1969-1973. 1998
|
| 43 | MMP13
|
| Structural analysis and promoter characterization of the human collagenase-3 (MMP13).
|
| Pendas AM, et al.
|
| Genomics 40 : 222-233. 1997
|
| 44 | MMP13
|
| Fine physical mapping of the human matrix metalloproteinase genes clustered on chromosome 11q22.3.
|
| Pendas AM, et al.
|
| Genomics 37 : 266-269. 1996
|
| 45 | MMP13
|
| The human collagenase-3 (CLG3) gene is located on chromosome 11q22.3 clustered to other members of the matrix metalloproteinase gene family.
|
| Pendas AM, et al.
|
| Genomics 26 : 615-618. 1995
|
| 46 | MMP13
|
| Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.
|
| Freije JMP, et al.
|
| J Biol Chem 269 : 16766-16773. 1994
|