1 | MMP12, NOS2
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| Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase.
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| Lee JT, Pamir N, Liu NC, Kirk EA, Averill MM, Becker L, Larson I, Hagman DK, Foster-Schubert KE, van Yserloo B, Bornfeldt KE, LeBoeuf RC, Kratz M, Heinecke JW.
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| Endocrinology 155(9):3409-20. doi: 10.1210/en.2014-1037. Epub 2014 Jun 10.
2014
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2 | GRN, MMP12, SLPI
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| Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
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| Suh HS, Choi N, Tarassishin L, Lee SC.
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| PLoS One 7(4):e35115. doi: 10.1371/journal.pone.0035115. Epub 2012 Apr 11.
2012
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3 | MMP12
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| Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis.
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| Qu P, Yan C, Du H.
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| Blood 117(17):4476-89. Epub 2011 Mar 4.
2011
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4 | MMP12
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| Overexpression of matrix metalloproteinase-12 (MMP-12) correlates with poor prognosis of hepatocellular carcinoma.
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| Ng KT, Qi X, Kong KL, Cheung BY, Lo CM, Poon RT, Fan ST, Man K.
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| Eur J Cancer 47(15):2299-305. Epub 2011 Jun 15.
2011
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5 | MMP12
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| Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults.
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| Mukhopadhyay S, Sypek J, Tavendale R, Gartner U, Winter J, Li W, Page K, Fleming M, Brady J, O'Toole M, Macgregor DF, Goldman S, Tam S, Abraham W, Williams C, Miller DK, Palmer CN.
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| J Allergy Clin Immunol 126(1):70-6.e16. Epub 2010 May 23.
2010
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6 | MMP12
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| MMP-12 catalytic domain recognizes and cleaves at multiple sites in human skin collagen type I and type III.
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| Taddese S, Jung MC, Ihling C, Heinz A, Neubert RH, Schmelzer CE.
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| Biochim Biophys Acta 1804(4):731-9. Epub 2009 Nov 22.
2010
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7 | ADAMDEC1, MMP12
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| Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis.
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| Crouser ED, Culver DA, Knox KS, Julian MW, Shao G, Abraham S, Liyanarachchi S, Macre JE, Wewers MD, Gavrilin MA, Ross P, Abbas A, Eng C.
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| Am J Respir Crit Care Med 179(10):929-38. Epub 2009 Feb 12.PMID: 19218196 2009
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8 | MMP12, MMP9
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| MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferation.
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| Dwivedi A, Slater SC, George SJ.
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| Cardiovasc Res 81(1):178-86. Epub 2008 Oct 13.
2009
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9 | MMP12
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| Matrix metalloproteinase-12 gene regulation by a PPAR alpha agonist in human monocyte-derived macrophages.
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| Souissi IJ, Billiet L, Cuaz-Pérolin C, Slimane MN, Rouis M.
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| Exp Cell Res 314(18):3405-14. Epub 2008 Sep 18.
2008
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10 | MMP12
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| Characterization of Ca2+ interactions with matrix metallopeptidase-12: implications for matrix metallopeptidase regulation.
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| Gossas T, Danielson UH.
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| Biochem J 398(3):393-8. 2006
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11 | MMP1, MMP10, MMP11, MMP12, MMP13, MMP14, MMP15, MMP16, MMP17, MMP19, MMP2, MMP20, MMP21, MMP23A, MMP23B, MMP24, MMP25, MMP26, MMP27, MMP28, MMP3, MMP7, MMP8, MMP9
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| Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry.
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| Visse R, Nagase H.
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| Circ Res 92(8):827-39. Review. 2003
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12 | MMP12
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| Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance.
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| Yang W, Arii S, Gorrin-Rivas MJ, Mori A, Onodera H, Imamura M.
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| Cancer 91(7):1277-83. 2001
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13 | MMP12
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| Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation
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| Kerkela E, Bohling T, Herva R, Uria JA, Saarialho-Kere U.
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| Bone 29(5):487-93. 2001
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14 | MMP12, MMP7
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| Accumulation of matrilysin (MMP-7) and macrophage metalloelastase (MMP-12) in actinic damage.
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| Saarialho-Kere U, Kerkela E, Jeskanen L, Hasan T, Pierce R, Starcher B, Raudasoja R, Ranki A, Oikarinen A, Vaalamo M.
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| J Invest Dermatol 113(4):664-72. 1999
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15 | MMP12
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| Discovery and analysis of inflammatory disease-related genes using cDNA microarrays.
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| Heller RA, Schena M, Chai A, Shalon D, Bedilion T, Gilmore J, Woolley DE, Davis RW.
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| Proc Natl Acad Sci U S A 94 : 2150-2155. 1997
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16 | MMP12
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| Human macrophage metalloelastase. Genomic organization, chromosomal location, gene linkage, and tissue-specific expression.
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| Belaaouaj A, et al.
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| J Biol Chem 270 : 14568-14575. 1995
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17 | MMP12
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| A genetic linkage map of the mouse : current applications and future prospects.
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| Copeland NG, et al.
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| Science 262 : 57-66. 1993
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18 | MMP12
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| Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages.
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| Shapiro SD, et al.
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| J Biol Chem 268 : 23824-23829. 1993
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