1 | ACTR2, CEBPB, MMD, SPRED2
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| Enhancer variants on chromosome 2p14 regulating SPRED2 and ACTR2 act as a signal amplifier to protect against rheumatoid arthritis.
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| Wang NN, Zhang Y, Jiang F, Zhu DL, Di CX, Hu SY, Chen XF, Zhi LQ, Rong Y, Ke X, Duan YY, Dong SS, Yang TL, Yang Z, Guo Y.
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| Am J Hum Genet. Apr 6;110(4):625-637. doi: 10.1016/j.ajhg.2023.02.012. Epub 2023 Mar 15. 2023
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2 | MMD, MMD2
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| Functional Analysis of Mmd2 and Related PAQR Genes During Sex Determination in Mice
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| Zhao L, Thomson E, Ng ET, Longmuss E, Svingen T, Bagheri-Fam S, Quinn A, Harley VR, Harrison LC, Pelosi E, Koopman P.
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| Sex Dev. 16(4):270-282. doi: 10.1159/000522668. Epub 2022 Mar 18. 2022
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3 | MMD
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| PAQR11 modulates monocyte-to-macrophage differentiation and pathogenesis of rheumatoid arthritis.
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| Lin Y, Huang M, Wang S, You X, Zhang L, Chen Y.
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| Immunology May;163(1):60-73. doi: 10.1111/imm.13303. Epub 2021 Jan 24. 2021
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4 | MMD
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| Adipose tissue lipolysis is regulated by PAQR11 via altering protein stability of phosphodiesterase 4D
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| Huang M, Lin Y, Wang L, You X, Wang S, Zhao J, Bai M, Li Z, Chen Y.
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| Mol Metab. May;47:101182. doi: 10.1016/j.molmet.2021.101182. Epub 2021 Feb 5 2021
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5 | MMD, PLAU
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| p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi.
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| Tan X, Banerjee P, Shi L, Xiao GY, Rodriguez BL, Grzeskowiak CL, Liu X, Yu J, Gibbons DL, Russell WK, Creighton CJ, Kurie JM.
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| Sci Adv. Jun 18;7(25):eabf4885. doi: 10.1126/sciadv.abf4885. 2021
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6 | MMD
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| Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11.
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| Tan X, Banerjee P, Guo HF, Ireland S, Pankova D, Ahn YH, Nikolaidis IM, Liu X, Zhao Y, Xue Y, Burns AR, Roybal J, Gibbons DL, Zal T, Creighton CJ, Ungar D, Wang Y, Kurie JM.
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| J Clin Invest. Jan 3;127(1):117-131. doi: 10.1172/JCI88736. Epub 2016 Nov 21. 2017
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7 | MMD, MMD2, PAQR3
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| Characterization of Golgi scaffold proteins and their roles in compartmentalizing cell signaling
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| Peng W, Lei Q, Jiang Z, Hu Z.
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| J Mol Histol. Aug;45(4):435-45. doi: 10.1007/s10735-013-9560-1. Epub 2013 Dec 14. 2014
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8 | MMD, MMD2
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| PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus.
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| Jin T, Ding Q, Huang H, Xu D, Jiang Y, Zhou B, Li Z, Jiang X, He J, Liu W, Zhang Y, Pan Y, Wang Z, Thomas WG, Chen Y.
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| Cell Res. Apr;22(4):661-76. doi: 10.1038/cr.2011.161. Epub 2011 Oct 4. 2012
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