Citations for
1DOT1L, KMT2A, MLLT1, MLLT3
Targeting recruitment of disruptor of telomeric silencing 1-like (DOT1L): characterizing the interactions between DOT1L and mixed lineage leukemia (MLL) fusion proteins.
Shen C, Jo SY, Liao C, Hess JL, Nikolovska-Coleska Z.
J Biol Chem 288(42):30585-96. doi: 10.1074/jbc.M113.457135. Epub 2013 Sep 1. 2013
2KMT2A, MLLT3
MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.
Horton SJ, Jaques J, Woolthuis C, van Dijk J, Mesuraca M, Huls G, Morrone G, Vellenga E, Schuringa JJ.
Leukemia 27(5):1116-26. doi: 10.1038/leu.2012.343. Epub 2012 Nov 26. 2013
3DOT1L, KMT2A, MLLT3
DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Nguyen AT, Taranova O, He J, Zhang Y.
Blood 117(25):6912-22. doi: 10.1182/blood-2011-02-334359. Epub 2011 Apr 26. 2011
4KMT2A, MLLT1, MLLT3
MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
Monroe SC, Jo SY, Sanders DS, Basrur V, Elenitoba-Johnson KS, Slany RK, Hess JL.
Exp Hematol 39(1):77-86.e1-5. doi: 10.1016/j.exphem.2010.09.003. Epub 2010 Sep 18. 2011
5ANKRD6, MLLT3
The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9.
Haribaskar R, Pütz M, Schupp B, Skouloudaki K, Bietenbeck A, Walz G, Schäfer T.
Biochem Biophys Res Commun 387(1):212-7. doi: 10.1016/j.bbrc.2009.07.012. Epub 2009 Jul 8. 2009
6MLLT3
MLLT3 regulates early human erythroid and megakaryocytic cell fate.
Pina C, May G, Soneji S, Hong D, Enver T.
Cell Stem Cell 2(3):264-73.PMID: 18371451 2008
7CCDC94, KMT2A, MLLT3, SHD
Three-way translocation involves MLL, MLLT3, and a novel cell cycle control gene, FLJ10374, in the pathogenesis of acute myeloid leukemia with t(9;11;19)(p22;q23;p13.3).
Vieira L, Sousa AC, Matos P, Marques B, Alaiz H, Ribeiro MJ, Braga P, da Silva MG, Jordan P.
Genes Chromosomes Cancer 45(5):455-69. 2006
8YEATS4 , MLLT1, MLLT3
The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.
Debernardi S, Bassini A, Jones LK, Chaplin T, Linder B, de Bruijn DR, Meese E, Young BD.
Blood 99(1):275-81. 2002
9AFDN, MLLT3
Granulocytic sarcomas in body cavities in childhood acute myeloid leukemias with 11q23/MLL rearrangements.
Johansson B, Fioretos T, Kullendorff CM, Wiebe T, Bekassy AN, Garwicz S, Forestier E, Roos G, Akerman M, Mitelman F, Billstrom R.
Genes Chromosomes Cancer 27(2):136-42. Review 2000
10MLLT3
DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis.
Strissel PL, Strick R, Tomek RJ, Roe BA, Rowley JD, Zeleznik-Le NJ.
Hum Mol Genet 9(11):1671-9. 2000
11AFF1, KMT2A, MLLT1, MLLT3
Identification of MLL and chimeric MLL gene products involved in 11q23 translocation and possible mechanisms of leukemogenesis by MLL truncation.
Joh T, et al.
Oncogene 13 : 1945-1953. 1996
12MLLT3
An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice : a method to create fusion oncogenes.
Corral J, et al.
Cell 85 : 853-861. 1996
13MLLT3
The MLLT3 gene maps between D9S156 and D9S171 and contains an unstable polymorphic trinucleotide repeat.
Walker GJ, et al.
Genomics 20 : 490-491. 1994
14AFF1, KMT2A, MLLT1, MLLT3
Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.
Nakamura T, et al.
Proc Natl Acad Sci U S A 90 : 4631-4635. 1993
15MLLT3
MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13.
Iida S, et al.
Oncogene 8 : 3085-3092. 1993