| 1 | DOT1L, KMT2A, MLLT1, MLLT3
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| Targeting recruitment of disruptor of telomeric silencing 1-like (DOT1L): characterizing the interactions between DOT1L and mixed lineage leukemia (MLL) fusion proteins.
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| Shen C, Jo SY, Liao C, Hess JL, Nikolovska-Coleska Z.
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| J Biol Chem 288(42):30585-96. doi: 10.1074/jbc.M113.457135. Epub 2013 Sep 1.
2013
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| 2 | KMT2A, MLLT3
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| MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.
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| Horton SJ, Jaques J, Woolthuis C, van Dijk J, Mesuraca M, Huls G, Morrone G, Vellenga E, Schuringa JJ.
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| Leukemia 27(5):1116-26. doi: 10.1038/leu.2012.343. Epub 2012 Nov 26.
2013
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| 3 | DOT1L, KMT2A, MLLT3
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| DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
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| Nguyen AT, Taranova O, He J, Zhang Y.
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| Blood 117(25):6912-22. doi: 10.1182/blood-2011-02-334359. Epub 2011 Apr 26.
2011
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| 4 | KMT2A, MLLT1, MLLT3
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| MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
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| Monroe SC, Jo SY, Sanders DS, Basrur V, Elenitoba-Johnson KS, Slany RK, Hess JL.
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| Exp Hematol 39(1):77-86.e1-5. doi: 10.1016/j.exphem.2010.09.003. Epub 2010 Sep 18.
2011
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| 5 | ANKRD6, MLLT3
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| The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9.
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| Haribaskar R, Pütz M, Schupp B, Skouloudaki K, Bietenbeck A, Walz G, Schäfer T.
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| Biochem Biophys Res Commun 387(1):212-7. doi: 10.1016/j.bbrc.2009.07.012. Epub 2009 Jul 8.
2009
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| 6 | MLLT3
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| MLLT3 regulates early human erythroid and megakaryocytic cell fate.
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| Pina C, May G, Soneji S, Hong D, Enver T.
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| Cell Stem Cell 2(3):264-73.PMID: 18371451 2008
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| 7 | CCDC94, KMT2A, MLLT3, SHD
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| Three-way translocation involves MLL, MLLT3, and a novel cell cycle control gene, FLJ10374, in the pathogenesis of acute myeloid leukemia with t(9;11;19)(p22;q23;p13.3).
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| Vieira L, Sousa AC, Matos P, Marques B, Alaiz H, Ribeiro MJ, Braga P, da Silva MG, Jordan P.
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| Genes Chromosomes Cancer 45(5):455-69. 2006
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| 8 | YEATS4 , MLLT1, MLLT3
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| The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.
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| Debernardi S, Bassini A, Jones LK, Chaplin T, Linder B, de Bruijn DR, Meese E, Young BD.
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| Blood 99(1):275-81. 2002
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| 9 | AFDN, MLLT3
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| Granulocytic sarcomas in body cavities in childhood acute myeloid leukemias with 11q23/MLL rearrangements.
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| Johansson B, Fioretos T, Kullendorff CM, Wiebe T, Bekassy AN, Garwicz S, Forestier E, Roos G, Akerman M, Mitelman F, Billstrom R.
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| Genes Chromosomes Cancer 27(2):136-42. Review 2000
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| 10 | MLLT3
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| DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis.
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| Strissel PL, Strick R, Tomek RJ, Roe BA, Rowley JD, Zeleznik-Le NJ.
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| Hum Mol Genet 9(11):1671-9. 2000
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| 11 | AFF1, KMT2A, MLLT1, MLLT3
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| Identification of MLL and chimeric MLL gene products involved in 11q23 translocation and possible mechanisms of leukemogenesis by MLL truncation.
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| Joh T, et al.
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| Oncogene 13 : 1945-1953. 1996
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| 12 | MLLT3
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| An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice : a method to create fusion oncogenes.
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| Corral J, et al.
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| Cell 85 : 853-861. 1996
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| 13 | MLLT3
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| The MLLT3 gene maps between D9S156 and D9S171 and contains an unstable polymorphic trinucleotide repeat.
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| Walker GJ, et al.
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| Genomics 20 : 490-491. 1994
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| 14 | AFF1, KMT2A, MLLT1, MLLT3
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| Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.
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| Nakamura T, et al.
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| Proc Natl Acad Sci U S A 90 : 4631-4635. 1993
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| 15 | MLLT3
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| MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13.
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| Iida S, et al.
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| Oncogene 8 : 3085-3092. 1993
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