| 1 | MLLT10, PICALM
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| A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis.
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| Conway AE, Scotland PB, Lavau CP, Wechsler DS.
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| Blood 121(23):4758-68. doi: 10.1182/blood-2012-06-435792. Epub 2013 Mar 13.
2013
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| 2 | MLLT10
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| CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12.
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| Mulaw MA, Krause AJ, Deshpande AJ, Krause LF, Rouhi A, La Starza R, Borkhardt A, Buske C, Mecucci C, Ludwig WD, Lottaz C, Bohlander SK.
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| Leukemia 26(5):1012-9. doi: 10.1038/leu.2011.307. Epub 2011 Nov 8.
2012
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| 3 | MLLT10
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| Common variation at 10p12.31 near MLLT10 influences meningioma risk.
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| Dobbins SE, Broderick P, Melin B, Feychting M, Johansen C, Andersson U, Brännström T, Schramm J, Olver B, Lloyd A, Ma YP, Hosking FJ, Lönn S, Ahlbom A, Henriksson R, Schoemaker MJ, Hepworth SJ, Hoffmann P, Mühleisen TW, Nöthen MM, Moebus S, Eisele L, Kosteljanetz M, Muir K, Swerdlow A, Simon M, Houlston RS.
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| Nat Genet 43(9):825-7. doi: 10.1038/ng.879.
2011
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| 4 | DOT1L, MLLT10
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| The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.
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| Mahmoudi T, Boj SF, Hatzis P, Li VS, Taouatas N, Vries RG, Teunissen H, Begthel H, Korving J, Mohammed S, Heck AJ, Clevers H.
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| PLoS Biol 8(11):e1000539.
2010
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| 5 | MLLT10
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| Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.
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| Lin YH, Kakadia PM, Chen Y, Li YQ, Deshpande AJ, Buske C, Zhang KL, Zhang Y, Xu GL, Bohlander SK.
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| Blood 114(3):651-8. Epub 2009 May 14.
2009
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| 6 | IKZF1, MLLT10, PICALM
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| The leukemogenic CALM/AF10 fusion protein alters the subcellular localization of the lymphoid regulator Ikaros.
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| Greif PA, Tizazu B, Krause A, Kremmer E, Bohlander SK.
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| Oncogene 27(20):2886-96. Epub 2007 Nov 26.PMID: 18037964 2008
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| 7 | PICALM, MLLT10, HOXA9
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| Acute monocytic leukemia with coexpression of minor BCR-ABL1 and PICALM-MLLT10 fusion genes along with overexpression of HOXA9.
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| Sindt A, Deau B, Brahim W, Staal A, Visanica S, Villarese P, Rault JP, Macintyre E, Delabesse E.
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| Genes Chromosomes Cancer 45(6):575-82. 2006
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| 8 | KMT2A, MLLT10
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| Translocation (10;11)(p12;q23) in childhood acute myeloid leukemia: incidence and complex mechanism.
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| Stasevich I, Utskevich R, Kustanovich A, Litvinko N, Savitskaya T, Chernyavskaya S, Saharova O, Aleinikova O.
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| Cancer Genet Cytogenet 169(2):114-20. 2006
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| 9 | MLLT10
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| MLL-MLLT10 fusion gene in pediatric acute megakaryoblastic leukemia.
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| Morerio C, Rapella A, Tassano E, Rosanda C, Panarello C.
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| Leuk Res 29(10):1223-6. Epub 2005 Apr 11. Review. 2005
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| 10 | KMT2A, MLLT10
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| MLL-MLLT10 fusion in acute monoblastic leukemia: variant complex rearrangements and 11q proximal breakpoint heterogeneity.
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| Morerio C, Rapella A, Rosanda C, Lanino E, Lo Nigro L, Di Cataldo A, Maserati E, Pasquali F, Panarello C.
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| Cancer Genet Cytogenet 152(2):108-12. Review. 2004
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| 11 | KMT2A, MLLT10
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| Molecular analysis of the genomic inversion and insertion of AF10 into MLL suggests a single-step event.
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| Chaplin T, Jones L, Debernardi S, Hill AS, Lillington DM, Young BD.
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| Genes Chromosomes Cancer 30(2):175-180. 2001
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| 12 | MLLT10
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| CALM-AF10 fusion gene in leukemias: simple and inversion-associated translocation (10;11).
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| Salmon-Nguyen F, Busson M, Daniel M, Leblanc T, Bernard OA, Berger R.
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| Cancer Genet Cytogenet 122(2):137-40. 2000
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| 13 | MLLT10, PICALM
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| Mixed-lineage leukemia with t(10;11)(p13;q21): an analysis of AF10-CALM and CALM-AF10 fusion mRNAs and clinical features.
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| Kumon K, et al.
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| Genes Chromosomes Cancer 25(1):33-9. 1999
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| 14 | MLLT10, PICALM
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| Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14-q21) suggests a potential role for truncated AF10 polypeptides.
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| Silliman CC, et al.
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| Leukemia 12 : 1404-1410. 1998
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| 15 | MLLT10, PICALM
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| The t(10;11)(p13;q14) in the U937 cell line results in the fusion of theAF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family.
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| Dreyling MH, et al.
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| Proc Natl Acad Sci U S A 93 : 4804-4809. 1996
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| 16 | CLP1, KMT2A, MLLT10
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| AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12).
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| Tanabe S, et al.
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| Blood 88 : 3535-3545. 1996
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| 17 | MLLT10
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| A novel class of zing finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia.
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| Chaplin T, et al.
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| Blood 85 : 1435-1441. 1995
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| 18 | MLLT10, MLLT6, NCOA2
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| The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.
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| Saha V, et al.
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| Proc Natl Acad Sci U S A 92 : 9737-9741. 1995
|