| 1 | MLH1, MLH3, TEX11, TEX15
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| Six polymorphisms in genes involved in DNA double-strand break repair and chromosome synapsis: association with male infertility.
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| Zhang X, Ding M, Ding X, Li T, Chen H.
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| Syst Biol Reprod Med. 61(4):187-93. doi: 10.3109/19396368.2015.1027014. Epub 2015 Jun 18 2015
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| 2 | MLH1, MLH3, MSH1, MSH3
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| Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease.
|
| Rogacheva MV, Manhart CM, Chen C, Guarne A, Surtees J, Alani E.
|
| J Biol Chem 289(9):5664-73. doi: 10.1074/jbc.M113.534644. Epub 2014 Jan 8.
2014
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| 3 | MLH1, MSH2
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| Promoter methylation of MLH1, PMS2, MSH2 and p16 is a phenomenon of advanced-stage HCCs.
|
| Hinrichsen I, Kemp M, Peveling-Oberhag J, Passmann S, Plotz G, Zeuzem S, Brieger A.
|
| PLoS One 9(1):e84453. doi: 10.1371/journal.pone.0084453. eCollection 2014.
2014
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| 4 | MLH1, MSH2
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| Promoter methylation and immunohistochemical expression of hMLH1 and hMSH2 in sporadic colorectal cancer: a study from India.
|
| Malhotra P, Anwar M, Kochhar R, Ahmad S, Vaiphei K, Mahmood S.
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| Tumour Biol 35(4):3679-87. doi: 10.1007/s13277-013-1487-3. Epub 2013 Dec 10.
2014
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| 5 | MLH1, MSH5, PMS2
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| Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility
|
| Ji G, Long Y, Zhou Y, Huang C, Gu A, Wang X.
|
| BMC Med. May 17;10:49. doi: 10.1186/1741-7015-10-49. 2012
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| 6 | MLH1
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| Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles.
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| Auclair J, Vaissière T, Desseigne F, Lasset C, Bonadona V, Giraud S, Saurin JC, Joly MO, Leroux D, Faivre L, Audoynaud C, Montmain G, Ruano E, Herceg Z, Puisieux A, Wang Q.
|
| Genes Chromosomes Cancer 50(3):178-85. doi: 10.1002/gcc.20842. Epub 2010 Dec 9.
2011
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| 7 | LRRFIP2, MLH1
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| A novel exonic rearrangement affecting MLH1 and the contiguous LRRFIP2 is a founder mutation in Portuguese Lynch syndrome families.
|
| Pinheiro M, Pinto C, Peixoto A, Veiga I, Mesquita B, Henrique R, Baptista M, Fragoso M, Sousa O, Pereira H, Marinho C, Moreira Dias L, Teixeira MR.
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| Genet Med 13(10):895-902.
2011
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| 8 | LRRFIP2, MLH1
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| Biallelic MLH1 SNP cDNA expression or constitutional promoter methylation can hide genomic rearrangements causing Lynch syndrome.
|
| Morak M, Koehler U, Schackert HK, Steinke V, Royer-Pokora B, Schulmann K, Kloor M, Höchter W, Weingart J, Keiling C, Massdorf T, Holinski-Feder E; German HNPCC consortium.
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| J Med Genet 48(8):513-9. Epub 2011 Jun 28.
2011
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| 9 | CMMRD, MLH1
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| Role for genetic anticipation in Lynch syndrome.
|
| Nilbert M, Timshel S, Bernstein I, Larsen K.
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| J Clin Oncol 27(3):360-4. Epub 2008 Dec 15.
2009
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| 10 | MLH1
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| Polymorphisms of MLH1 in benign prostatic hyperplasia and sporadic prostate cancer.
|
| Tanaka Y, Zaman MS, Majid S, Liu J, Kawakami K, Shiina H, Tokizane T, Dahiya AV, Sen S, Nakajima K.
|
| Biochem Biophys Res Commun 383(4):440-4. Epub 2009 Apr 11.
2009
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| 11 | HNPCC1, HNPCC2, MLH1, TACSTD1
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| Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.
|
| Niessen RC, Hofstra RM, Westers H, Ligtenberg MJ, Kooi K, Jager PO, de Groote ML, Dijkhuizen T, Olderode-Berends MJ, Hollema H, Kleibeuker JH, Sijmons RH.
|
| Genes Chromosomes Cancer 48(8):737-44.PMID: 19455606 2009
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| 12 | HNPCC2, MLH1
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| Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer.
|
| Hitchins MP, Ward RL.
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| J Med Genet 46(12):793-802. Epub 2009 Jun 29. 2009
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| 13 | EPCAM, MLH1
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| Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.
|
| Niessen RC, Hofstra RM, Westers H, Ligtenberg MJ, Kooi K, Jager PO, de Groote ML, Dijkhuizen T, Olderode-Berends MJ, Hollema H, Kleibeuker JH, Sijmons RH.
|
| Genes Chromosomes Cancer 48(8):737-44.PMID: 19455606 2009
|
| 14 | HNPCC2, HNPCC4, MLH1, PMS2
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| Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer.
|
| Montazer Haghighi M, Radpour R, Aghajani K, Zali N, Molaei M, Zali MR.
|
| Int J Colorectal Dis 24(8):885-93. Epub 2009 May 29.PMID: 19479271 2009
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| 15 | MLH1, MSH2, MSH6, PMS2
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| Germ-line mutations in mismatch repair genes associated with prostate cancer.
|
| Grindedal EM, Møller P, Eeles R, Stormorken AT, Bowitz-Lothe IM, Landrø SM, Clark N, Kvåle R, Shanley S, Maehle L.
|
| Cancer Epidemiol Biomarkers Prev 18(9):2460-7. Epub 2009 Sep 1.PMID: 19723918 2009
|
| 16 | CTDSPL, MLH1
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| Frequent alterations of hMLH1 and RBSP3/HYA22 at chromosomal 3p22.3 region in early and late-onset breast carcinoma: clinical and prognostic significance.
|
| Sinha S, Singh RK, Alam N, Roy A, Roychoudhury S, Panda CK.
|
| Cancer Sci 99(10):1984-91.
2008
|
| 17 | MLH1
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| Evidence that a mutation in the MLH1 3'-untranslated region confers a mutator phenotype and mismatch repair deficiency in patients with relapsed leukemia.
|
| Mao G, Pan X, Gu L.
|
| J Biol Chem 283(6):3211-6. Epub 2007 Dec 4. 2008
|
| 18 | CMMRD, MLH1, MSH2, MSH6, PMS2
|
| Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg?
|
| Wimmer K, Etzler J.
|
| Hum Genet 124(2):105-22. Epub 2008 Aug 18. Review. 2008
|
| 19 | APC, BRCA1, BRCA2, CDH1, CDKN2A, MLH1, MSH2, MSH6, PMS2, PRSS1, PTEN, RB1, SPINK1, STK11, TP53
|
| Inherited susceptibility to common cancers.
|
| Foulkes WD.
|
| N Engl J Med 359(20):2143-53. No abstract available.
2008
|
| 20 | MLH1, RAD9A
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| Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1.
|
| He W, Zhao Y, Zhang C, An L, Hu Z, Liu Y, Han L, Bi L, Xie Z, Xue P, Yang F, Hang H.
|
| Nucleic Acids Res 36(20):6406-17. Epub 2008 Oct 8.
2008
|
| 21 | BHLHE40, BHLHE41, MLH1
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| Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2.
|
| Nakamura H, Tanimoto K, Hiyama K, Yunokawa M, Kawamoto T, Kato Y, Yoshiga K, Poellinger L, Hiyama E, Nishiyama M.
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| Oncogene 27(30):4200-9. Epub 2008 Mar 17. 2008
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| 22 | DLEC1, MLH1
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| DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma.
|
| Seng TJ, Currey N, Cooper WA, Lee CS, Chan C, Horvath L, Sutherland RL, Kennedy C, McCaughan B, Kohonen-Corish MR.
|
| Br J Cancer 99(2):375-82. Epub 2008 Jul 1.PMID: 18594535 2008
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| 23 | MLH1, HNPCC2
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| MLH1 germline epimutations in selected patients with early-onset non-polyposis colorectal cancer.
|
| Valle L, Carbonell P, Fernandez V, Dotor A, Sanz M, Benitez J, Urioste M.
|
| Clin Genet 71(3):232-7. 2007
|
| 24 | MLH1, HNPCC2
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| Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach.
|
| Ollikainen M, Hannelius U, Lindgren CM, Abdel-Rahman WM, Kere J, Peltomaki P.
|
| Oncogene [Epub ahead of print] 2007
|
| 25 | MSH2, MLH1, HNPCC1, HNPCC2
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| Partial duplications of the MSH2 and MLH1 genes in hereditary nonpolyposis colorectal cancer.
|
| Baert-Desurmont S, Buisine MP, Bessenay E, Frerot S, Lovecchio T, Martin C, Olschwang S, Wang Q, Frebourg T.
|
| Eur J Hum Genet 15(3):383-6. Epub 2007 Jan 17. 2007
|
| 26 | HNPCC1, HNPCC2, HNPCC3, HNPCC4, HNPCC5, HNPCC6, HNPCC7, MLH1, MSH2, MSH6, PMS2
|
| Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).
|
| Vasen HF, Moslein G, Alonso A, Bernstein I, Bertario L, Blanco I, Burn J, Capella G, Engel C, Frayling I, Friedl W, Hes FJ, Hodgson S, Mecklin JP, Moller P, Nagengast F, Parc Y, Renkonen-Sinisalo L, Sampson JR, Stormorken A, Wijnen J.
|
| J Med Genet 44(6):353-62. Epub 2007 Feb 27. 2007
|
| 27 | FANCJ,MLH1,MSH2
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| The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells.
|
| Peng M, Litman R, Xie J, Sharma S, Brosh RM Jr, Cantor SB.
|
| EMBO J 26(13):3238-49. Epub 2007 Jun 21. 2007
|
| 28 | CMMRD, MLH1, MSH2, MSH6, PMS2
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| Biallelic germline mutations of mismatch-repair genes: a possible cause for multiple pediatric malignancies.
|
| Poley JW, Wagner A, Hoogmans MM, Menko FH, Tops C, Kros JM, Reddingius RE, Meijers-Heijboer H, Kuipers EJ, Dinjens WN; Rotterdam Initiative on Gastrointestinal Hereditary Tumors.
|
| Cancer 109(11):2349-56.
2007
|
| 29 | HNPCC2, MLH1
|
| Mismatch repair polymorphisms and colorectal polyps: hMLH1-93G>A variant modifies risk associated with smoking.
|
| Yu JH, Bigler J, Whitton J, Potter JD, Ulrich CM.
|
| Am J Gastroenterol 101(6):1313-9. 2006
|
| 30 | HNPCC1, HNPCC2, MSH2, MLH1
|
| Evidence for genetic anticipation in hereditary non-polyposis colorectal cancer.
|
| Westphalen AA, Russell AM, Buser M, Berthod CR, Hutter P, Plasilova M, Mueller H, Heinimann K.
|
| Hum Genet 116(6):461-5. Epub 2005 Mar 17. 2005
|
| 31 | MTS2, MLH1
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| Identification of Muir-Torre syndrome among patients with sebaceous tumors and keratoacanthomas: role of clinical features, microsatellite instability, and immunohistochemistry.
|
| Ponti G, Losi L, Di Gregorio C, Roncucci L, Pedroni M, Scarselli A, Benatti P, Seidenari S, Pellacani G, Lembo L, Rossi G, Marino M, Lucci-Cordisco E, de Leon MP.
|
| Cancer 103(5):1018-25. 2005
|
| 32 | MSH2, MLH1, MSH6, PMS2, HNPCC1, HNPCC2, HNPCC5, HNPCC4
|
| Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
|
| van der Klift H, Wijnen J, Wagner A, Verkuilen P, Tops C, Otway R, Kohonen-Corish M, Vasen H, Oliani C, Barana D, Moller P, Delozier-Blanchet C, Hutter P, Foulkes W, Lynch H, Burn J, Moslein G, Fodde R.
|
| Genes Chromosomes Cancer 44(2):123-38. 2005
|
| 33 | MSH2, MLH1, MSH6, PMS2, MLH3, PMS1, HNPCC1, HNPCC2, HNPCC5, HNPCC4, HNPCC3, HNPCC6
|
| Lynch syndrome genes.
|
| Peltomaki P.
|
| Fam Cancer 4(3):227-32. Review. 2005
|
| 34 | MLH1, HNPCC2
|
| MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.
|
| Hitchins M, Williams R, Cheong K, Halani N, Lin VA, Packham D, Ku S, Buckle A, Hawkins N, Burn J, Gallinger S, Goldblatt J, Kirk J, Tomlinson I, Scott R, Spigelman A, Suter C, Martin D, Suthers G, Ward R.
|
| Gastroenterology 129(5):1392-9. 2005
|
| 35 | MLH1, MSH2, HNPCC1, HNPCC2, ,
|
| Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.
|
| Pinol V, Castells A, Andreu M, Castellvi-Bel S, Alenda C, Llor X, Xicola RM, Rodriguez-Moranta F, Paya A, Jover R, Bessa X; Gastrointestinal Oncology Group of the Spanish Gastroenterological Association.
|
| JAMA 293(16):1986-94. 2005
|
| 36 | HNPCC1, HNPCC2, HNPCC3, HNPCC4, HNPCC5, HNPCC6, HNPCC7, MLH1, MSH2, MSH6, PMS2
|
| Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database.
|
| Peltomaki P, Vasen H.
|
| Dis Markers 20(4-5):269-76. Review. 2004
|
| 37 | MLH1, MSH3
|
| Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression.
|
| Plaschke J, Krüger S, Jeske B, Theissig F, Kreuz FR, Pistorius S, Saeger HD, Iaccarino I, Marra G, Schackert HK.
|
| Cancer Res 64(3):864-70.
2004
|
| 38 | MLH1
|
| Methylation profile of the MLH1 promoter region and their relationship to colorectal carcinogenesis
|
| Miyakura Y, Sugano K, Konishi F, Fukayama N, Igarashi S, Kotake K, Matsui T, Koyama Y, Maekawa M, Nagai H.
|
| Genes Chromosomes Cancer 36(1):17-25. 2003
|
| 39 | HNPCC1, MLH1, HNPCC2
|
| Genomic deletions in MSH2 or MLH1 are a frequent cause of hereditary non-polyposis colorectal cancer: identification of novel and recurrent deletions by MLPA.
|
| Taylor CF, Charlton RS, Burn J, Sheridan E, Taylor GR.
|
| Hum Mutat 22(6):428-33. 2003
|
| 40 | MLH1, MSH2, HNPCC2
|
| Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms.
|
| Yuan ZQ, Gottlieb B, Beitel LK, Wong N, Gordon PH, Wang Q, Puisieux A, Foulkes WD, Trifiro M.
|
| Hum Mutat 19(2):108-13. 2002
|
| 41 | MLH1
|
| Association of Crohn's disease and ulcerative colitis with haplotypes of the MLH1 gene in Italian inflammatory bowel disease patients.
|
| Annese V, Piepoli A, Andriulli A, Latiano A, Napolitano G, Li HH, Forabosco P, Devoto M.
|
| J Med Genet 39(5):332-4. No abstract available. 2002
|
| 42 | CDKN2A, DLC1, EXT1, MLH1, PTEN, RB1, TP53, TP73
|
| Molecular pathogenesis of human hepatocellular carcinoma.
|
| Thorgeirsson SS, Grisham JW.
|
| Nat Genet 31(4):339-46. 2002
|
| 43 | MLH1, MLH3, PMS1, PMS2
|
| The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2.
|
| Kondo E, Horii A, Fukushige S.
|
| Nucleic Acids Res 29(8):1695-702. 2001
|
| 44 | MLH1, MSH2
|
| Hereditary and somatic DNA mismatch repair gene mutations in sporadic endometrial carcinoma.
|
| Chadwick RB, Pyatt RE, Niemann TH, Richards SK, Johnson CK, Stevens MW, Meek JE, Hampel H, Prior TW, de la Chapelle A.
|
| J Med Genet 38(7):461-6. No abstract available. 2001
|
| 45 | HNPCC1, MLH1, MSH2
|
| Family history characteristics, tumor microsatellite instability and germline MSH2 and MLH1 mutations in hereditary colorectal cancer.
|
| Bapat BV, et al.
|
| Hum Genet 104(2):167-76. 1999
|
| 46 | MLH1
|
| MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers.
|
| Simpkins SB, et al.
|
| Hum Mol Genet 8(4):661-6. 1999
|
| 47 | MLH1
|
| Human MLH1 deficiency predisposes to hematological malignancy and neurofibromatosis type 1.
|
| Ricciardone MD, et al.
|
| Cancer Res 59(2):290-3. 1999
|
| 48 | MLH1
|
| Neurofibromatosis and early onset of cancers in hMLH1-deficient children.
|
| Wang Q, et al.
|
| Cancer Res 59(2):294-7. 1999
|
| 49 | MLH1, MSH3
|
| Frequent loss of heterozygosity at the DNA mismatch-repair loci hMLH1 and hMSH3 in sporadic breast cancer.
|
| Benachenhou N, et al.
|
| Br J Cancer 79(7-8):1012-7. 1999
|
| 50 | MLH1, PMS2
|
| The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer.
|
| Guerrette S, et al.
|
| J Biol Chem 274(10):6336-41. 1999
|
| 51 | MLH1
|
| A core promoter and a frequent single-nucleotide polymorphism of the mismatch repair gene hMLH1.
|
| Ito E, et al.
|
| Biochem Biophys Res Commun 256(3):488-94. 1999
|
| 52 | MLH1, PMS2L1, PMS2L15, PMS2L14, PMS2L16
|
| The human PMS2L proteins do not interact with hMLH1, a major DNA mismatch repair protein.
|
| Kondo E, et al.
|
| J Biochem (Tokyo) 125(4):818-25. 1999
|
| 53 | MSH2, MLH1
|
| Immunocytochemical detection of hMSH2 and hMLH1 expression in oral SCC.
|
| Lo Muzio L, et al.
|
| Anticancer Res 19(2A):933-40. 1999
|
| 54 | MLH1, MSH6, PMS1, PMS2, MSH2
|
| Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer.
|
| Wang Q, et al.
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| Hum Genet 105(1-2):79-85. 1999
|
| 55 | MLH1
|
| Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: The predominant role of hMLH1.
|
| Wheeler JM, et al.
|
| Proc Natl Acad Sci U S A 96(18):10296-10301. 1999
|
| 56 | MLH1, MSH2
|
| Assessment of pathogenicity criteria for constitutional missense mutations of the hereditary nonpolyposis colorectal cancer genes MLH1 and MSH2.
|
| Genuardi M, et al.
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| Eur J Hum Genet 7(7):778-82 1999
|
| 57 | MLH1, MSH2
|
| Characterization of MLH1 and MSH2 alternative splicing and its relevance to molecular testing of colorectal cancer susceptibility.
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| Genuardi M, Viel A, Bonora D, Capozzi E, Bellacosa A, Leonardi F, Valle R, Ventura A, Pedroni M, Boiocchi M, Neri G.
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| Hum Genet 102(1):15-20. 1998
|
| 58 | MLH1, MSH3, TSG3B, TSG5B
|
| High resolution deletion mapping reveals frequent allelic losses at the DNA mismatch repair loci hMLH1 and hMSH3 in non-small cell lung cancer.
|
| Benachenhou N, et al.
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| Int J Cancer 77 : 173-180. 1998
|
| 59 | HNPCC1, MLH1, MSH2
|
| Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
|
| Farrington SM, et al.
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| Am J Hum Genet 63 : 749-759. 1998
|
| 60 | APC, BRCA1, DPP4, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TP53, VHL, WT1, FAP
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| Tumour suppressor gene mutations in humans and mice : parallels and contrasts.
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| Hooper ML.
|
| EMBO J 17(23):6783-9. 1998
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| 61 | MSH6, MLH1, MSH2, MSH3
|
| Allelic losses and DNA methylation at DNA mismatch repair loci in sporadic colorectal cancer.
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| Benachenhou N, et al.
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| Carcinogenesis 19 : 1925-1929. 1998
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| 62 | ATM, ATR, BLM, MLH1, RAD51, RPA1, RPA2, RPA3
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| Changes in protein composition of meiotic nodules during mammalian meiosis.
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| Plug AW, et al.
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| J Cell Sci 111 ( Pt 4):413-23. 1998
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| 63 | HNPCC1, MLH1, MSH2
|
| Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer.
|
| Viel A, et al.
|
| Genes Chromosomes Cancer 18 : 8-18. 1997
|
| 64 | HNPCC1, MLH1, MSH2
|
| Mutations in MLH1 are more frequent than in MSH2 in sporadic colorectal cancers with microsatellite instability.
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| Herfarth KKF, et al.
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| Genes Chromosomes Cancer 18 : 42-49. 1997
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| 65 | HNPCC1, HNPCC3, HNPCC4, MLH1, MHS2, PMS1, PMS2
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| Molecular basis of HNPCC: mutations of MMR genes.
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| Papadopoulos N, Lindblom A.
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| Hum Mutat 10(2):89-99. 1997
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| 66 | MLH1
|
| Hereditary nonpolyposis colorectal cancer: causative role of a germline missense mutation in the hMLH1 gene confirmed by the independent occurrence of the same somatic mutation in tumour tissue.
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| Wang Y, Friedl W, Lamberti C, Ruelfs C, Kruse R, Propping P.
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| Hum Genet 100(3-4):362-4. 1997
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| 67 | HNPCC1, HNPCC3, HNPCC4, MLH1, MSH2, PMS1, PMS2
|
| Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
|
| Wijnen J, Khan PM, Vasen H, van der Klift H, Mulder A, van Leeuwen-Cornelisse I, Bakker B, Losekoot M, Moller P, Fodde R.
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| Am J Hum Genet 61(2):329-35. 1997
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| 68 | HNPCC1, MLH1, MSH2
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| Hereditary nonpolyposis colorectal cancer (HNPCC) : eight novel germline mutations in hMSH2 or hMLH1 gene.
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| Wehner M, Buschhausen L, Lamberti C, Kruse R, Caspari R, Propping P, Friedl W.
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| Hum Mutat 10(3):241-4. 1997
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| 69 | MLH1
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| A human compound heterozygote for two MLH1 missense mutations.
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| Hackman P, Tannergard P, Osei-Mensa S, Chen J, Kane MF, Kolodner R, Lambert B, Hellgren D, Lindblom A.
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| Nat Genet 17(2):135-6. 1997
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| 70 | HNPCC1, MLH1, MSH2
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| Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer.
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| Peltomaki P, Vasen HF.
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| Gastroenterology 113(4):1146-58. 1997
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| 71 | MLH1, HNPCC2
|
| Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16.
|
| Wijnen J, et al.
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| Am J Hum Genet 58 : 300-307. 1996
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| 72 | MSH2, MLH1, PMS1, PMS2, HNPCC1, HNPCC2, HNPCC3, HNPCC4
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| Analysis of mismatch repair genes in hereditary non-polyposis colorectalcancer patients.
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| Liu B, et al.
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| Nat Med 2 : 169-174. 1996
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| 73 | MLH1
|
| Somatic mutations of a human mismatch repair gene, hMLH1, in tumors from patients with multiple primary cancers.
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| Sasaki S, et al.
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| Hum Mutat 7 : 275-278. 1996
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| 74 | HNPCC1, HNPCC2, MLH1, MHS2
|
| DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer.
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| Nystrm-Lahti M, et al.
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| Hum Mol Genet 5 : 763-769. 1996
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| 75 | HNPCC1, HNPCC2, MLH1, MSH2
|
| Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer.
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| Moslein G, et al.
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| Hum Mol Genet 5 : 1245-1252. 1996
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| 76 | HNPCC1, HNPCC2, MLH1, MSH2
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| Mutation screening of MSH2 and MLH1 mRNA in hereditary non-polyposis colon cancer syndrome.
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