| 1 | MICU1, MICU1D
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| Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood.
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| Lewis-Smith D, Kamer KJ, Griffin H, Childs AM, Pysden K, Titov D, Duff J, Pyle A, Taylor RW, Yu-Wai-Man P, Ramesh V, Horvath R, Mootha VK, Chinnery PF.
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| Neurol Genet 2(2):e59. doi: 10.1212/NXG.0000000000000059. eCollection 2016 Apr.
2016
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| 2 | MCU, MICU1, MICU2, SMDT1
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| Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex.
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| Tsai MF, Phillips CB, Ranaghan M, Tsai CW, Wu Y, Willliams C, Miller C.
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| Elife 5. pii: e15545. doi: 10.7554/eLife.15545. [Epub ahead of print]
2016
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| 3 | MICU1
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| MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration.
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| Antony AN, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, Rubin E, Csordás G, Seifert EL, Hoek JB, Hajnóczky G.
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| Nat Commun 7:10955. doi: 10.1038/ncomms10955.
2016
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| 4 | MICU1, MICU2
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| Functional roles of MICU1 and MICU2 in mitochondrial Ca(2+) uptake.
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| Matesanz-Isabel J, Arias-Del-Val J, Alvarez-Illera P, Fonteriz RI, Montero M, Alvarez J.
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| Biochim Biophys Acta 1858(6):1110-7. doi: 10.1016/j.bbamem.2016.02.022. Epub 2016 Feb 18.
2016
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| 5 | MICU1, MICU2, SMDT1
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| EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter.
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| Vais H, Mallilankaraman K, Mak DO, Hoff H, Payne R, Tanis JE, Foskett JK.
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| Cell Rep 14(3):403-10. doi: 10.1016/j.celrep.2015.12.054. Epub 2016 Jan 7.
2016
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| 6 | MCU, MICU1, SMDT1
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| Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2.).
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| Waldeck-Weiermair M, Malli R, Parichatikanond W, Gottschalk B, Madreiter-Sokolowski CT, Klec C, Rost R, Graier WF.
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| Sci Rep 5:15602. doi: 10.1038/srep15602.
2015
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| 7 | MCU, MICU1, MICU2
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| Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
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| Lee Y, Min CK, Kim TG, Song HK, Lim Y, Kim D, Shin K, Kang M, Kang JY, Youn HS, Lee JG, An JY, Park KR, Lim JJ, Kim JH, Kim JH, Park ZY, Kim YS, Wang J, Kim do H, Eom SH.
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| EMBO Rep 16(10):1318-33. doi: 10.15252/embr.201540436. Epub 2015 Sep 3.
2015
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| 8 | CHCHD40, MICU1, MICU2
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| The Ca(2+)-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca(2+) Uptake.
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| Petrungaro C, Zimmermann KM, Küttner V, Fischer M, Dengjel J, Bogeski I, Riemer J.
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| Cell Metab 22(4):721-33. doi: 10.1016/j.cmet.2015.08.019. Epub 2015 Sep 17.
2015
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| 9 | EFHD1, MCU, MICU1
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| Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells.
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| Henzi T, Schwaller B.
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| PLoS One 10(11):e0142005. doi: 10.1371/journal.pone.0142005. eCollection 2015.
2015
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| 10 | MICU1, SLC25A23
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| SLC25A23 augments mitochondrial Ca˛⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell death.
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| Hoffman NE, Chandramoorthy HC, Shanmughapriya S, Zhang XQ, Vallem S, Doonan PJ, Malliankaraman K, Guo S, Rajan S, Elrod JW, Koch WJ, Cheung JY, Madesh M.
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| Mol Biol Cell 25(6):936-47. doi: 10.1091/mbc.E13-08-0502. Epub 2014 Jan 15. 2014
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| 11 | MICU1, MICU1D
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| Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.
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| Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R; UK10K Consortium, Duchen MR, Muntoni F, Sheridan E.
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| Nat Genet 46(2):188-93. doi: 10.1038/ng.2851. Epub 2013 Dec 15.
2014
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| 12 | MICU1, MICU2
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| MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity.
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| Patron M, Checchetto V, Raffaello A, Teardo E, Vecellio Reane D, Mantoan M, Granatiero V, Szabň I, De Stefani D, Rizzuto R.
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| Mol Cell 53(5):726-37. doi: 10.1016/j.molcel.2014.01.013. Epub 2014 Feb 20.
2014
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| 13 | MICU1, MICU2
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| MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter.
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| Kamer KJ, Mootha VK.
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| EMBO Rep 15(3):299-307. doi: 10.1002/embr.201337946. Epub 2014 Feb 6.
2014
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| 14 | MICU1, MICU2
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| Regulation of the mitochondrial Ca(2+) uniporter by MICU1 and MICU2.
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| Kevin Foskett J, Madesh M.
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| Biochem Biophys Res Commun 449(4):377-83. doi: 10.1016/j.bbrc.2014.04.146. Epub 2014 May 1. No abstract available.
2014
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| 15 | MCUR1, MICU1, MICU2, SMDT1
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| The uniporter: from newly identified parts to function.
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| Kamer KJ, Sancak Y, Mootha VK.
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| Biochem Biophys Res Commun 449(4):370-2. doi: 10.1016/j.bbrc.2014.04.143. Epub 2014 May 9. No abstract available.
2014
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| 16 | MCUR1, MICU1, MICU2, SMDT1
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| The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications.
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| Marchi S, Pinton P.
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| J Physiol 592(5):829-39. doi: 10.1113/jphysiol.2013.268235. Epub 2013 Dec 23. Review.
2014
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| 17 | MCU, MICU1
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| MICU1 motifs define mitochondrial calcium uniporter binding and activity.
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| Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, Madesh M.
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| Cell Rep 5(6):1576-88. doi: 10.1016/j.celrep.2013.11.026. Epub 2013 Dec 12.
2013
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| 18 | MCU, MICU1, MICU2, SMDT1
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| EMRE is an essential component of the mitochondrial calcium uniporter complex.
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| Sancak Y, Markhard AL, Kitami T, Kovács-Bogdán E, Kamer KJ, Udeshi ND, Carr SA, Chaudhuri D, Clapham DE, Li AA, Calvo SE, Goldberger O, Mootha VK.
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| Science 342(6164):1379-82. doi: 10.1126/science.1242993. Epub 2013 Nov 14.
2013
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| 19 | MICU1
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| MICU1 motifs define mitochondrial calcium uniporter binding and activity.
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| Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, Madesh M.
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| Cell Rep 5(6):1576-88. doi: 10.1016/j.celrep.2013.11.026. Epub 2013 Dec 12.
2013
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| 20 | MICU1
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| MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca˛⁺ uniporter.
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| Csordás G, Golenár T, Seifert EL, Kamer KJ, Sancak Y, Perocchi F, Moffat C, Weaver D, de la Fuente Perez S, Bogorad R, Koteliansky V, Adijanto J, Mootha VK, Hajnóczky G.
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| Cell Metab 17(6):976-87. doi: 10.1016/j.cmet.2013.04.020.
2013
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| 21 | MICU1
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| CBARA1 plays a role in stemness and proliferation of human embryonic stem cells.
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| Chen K, Hsu LT, Wu CY, Chang SY, Huang HT, Chen W.
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| PLoS One 8(5):e63653. doi: 10.1371/journal.pone.0063653. Print 2013.
2013
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| 22 | MCU, MICU1
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| Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells.
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| Alam MR, Groschner LN, Parichatikanond W, Kuo L, Bondarenko AI, Rost R, Waldeck-Weiermair M, Malli R, Graier WF.
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| J Biol Chem 287(41):34445-54. doi: 10.1074/jbc.M112.392084. Epub 2012 Aug 17. 2012
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| 23 | MCU, MICU1
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| MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
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| Mallilankaraman K, Doonan P, Cárdenas C, Chandramoorthy HC, Müller M, Miller R, Hoffman NE, Gandhirajan RK, Molgó J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M.
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| Cell 151(3):630-44. doi: 10.1016/j.cell.2012.10.011.
2012
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| 24 | LETM1, MICU1, UCP2, UCP3
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| Leucine zipper EF hand-containing transmembrane protein 1 (Letm1) and uncoupling proteins 2 and 3 (UCP2/3) contribute to two distinct mitochondrial Ca2+ uptake pathways.
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| Waldeck-Weiermair M, Jean-Quartier C, Rost R, Khan MJ, Vishnu N, Bondarenko AI, Imamura H, Malli R, Graier WF.
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| J Biol Chem 286(32):28444-55. Epub 2011 May 25. 2011
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| 25 | MCU, MICU1
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| A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
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| De Stefani D, Raffaello A, Teardo E, Szabň I, Rizzuto R.
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| Nature 476(7360):336-40. doi: 10.1038/nature10230. 2011
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| 26 | MCU, MICU1
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| Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
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| Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, Bao XR, Strittmatter L, Goldberger O, Bogorad RL, Koteliansky V, Mootha VK.
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| Nature 476(7360):341-5. doi: 10.1038/nature10234. 2011
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| 27 | MICU1
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| MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake.
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| Perocchi F, Gohil VM, Girgis HS, Bao XR, McCombs JE, Palmer AE, Mootha VK.
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| Nature 467(7313):291-6. Epub 2010 Aug 8.PMID: 20693986 2010
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| 28 | BCL7B, MICU1
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| Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients.
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| Natter S, et al.
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| FASEB J 12(14):1559-69 1998
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| 29 | MICU1
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| Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients.
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| Natter S, Seiberler S, Hufnagl P, Binder BR, Hirschl AM, Ring J, Abeck D, Schmidt T, Valent P, Valenta R.
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| FASEB J 12(14):1559-69. 1998
|