| 1 | BACH2, MEN1
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| The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis.
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| Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, Maruyama S, Kometani K, Kurosaki T, Ohara O, Nakayama T, Yamashita M.
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| Nat Commun 5:3555. doi: 10.1038/ncomms4555.
2014
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| 2 | MEN1
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| MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair.
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| Fang M, Xia F, Mahalingam M, Virbasius CM, Wajapeyee N, Green MR.
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| Mol Cell Biol 33(13):2635-47. doi: 10.1128/MCB.00167-13. Epub 2013 May 6.
2013
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| 3 | MEN1
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| Menin mediates epigenetic regulation via histone H3 lysine 9 methylation.
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| Yang YJ, Song TY, Park J, Lee J, Lim J, Jang H, Kim YN, Yang JH, Song Y, Choi A, Lee HY, Jo CH, Han JW, Kim ST, Youn HD, Cho EJ.
|
| Cell Death Dis 4:e583. doi: 10.1038/cddis.2013.98.
2013
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| 4 | MEN1, YAP1
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| Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription.
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| Xu B, Li SH, Zheng R, Gao SB, Ding LH, Yin ZY, Lin X, Feng ZJ, Zhang S, Wang XM, Jin GH.
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| Proc Natl Acad Sci U S A 110(43):17480-5. doi: 10.1073/pnas.1312022110. Epub 2013 Oct 7.
2013
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| 5 | JUND, KMT2A, MEN1, PSIP1
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| The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
|
| Huang J, Gurung B, Wan B, Matkar S, Veniaminova NA, Wan K, Merchant JL, Hua X, Lei M.
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| Nature 482(7386):542-6. doi: 10.1038/nature10806. 2012
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| 6 | MEN1
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| Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.
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| Shi A, Murai MJ, He S, Lund G, Hartley T, Purohit T, Reddy G, Chruszcz M, Grembecka J, Cierpicki T.
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| Blood 120(23):4461-9. doi: 10.1182/blood-2012-05-429274. Epub 2012 Aug 30.
2012
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| 7 | MEN1
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| Glucose-mediated repression of menin promotes pancreatic β-cell proliferation.
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| Zhang H, Li W, Wang Q, Wang X, Li F, Zhang C, Wu L, Long H, Liu Y, Li X, Luo M, Li G, Ning G.
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| Endocrinology 153(2):602-11. doi: 10.1210/en.2011-1460. Epub 2011 Dec 13.
2012
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| 8 | AIP, CDKN1B, MEN1
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| Novel mutations in MEN1, CDKN1B and AIP genes in patients with multiple endocrine neoplasia type 1 syndrome in Spain.
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| Belar O, De La Hoz C, Pérez-Nanclares G, Castańo L, Gaztambide S; Spanish MEN1 Group.
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| Clin Endocrinol (Oxf) 76(5):719-24. doi: 10.1111/j.1365-2265.2011.04269.x.
2012
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| 9 | AKT1, MEN1
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| The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization.
|
| Wang Y, Ozawa A, Zaman S, Prasad NB, Chandrasekharappa SC, Agarwal SK, Marx SJ.
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| Cancer Res 71(2):371-82. Epub 2010 Dec 2.
2011
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| 10 | ATRX, DAXX, MEN1
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| DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors.
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| Jiao Y, Shi C, Edil BH, de Wilde RF, Klimstra DS, Maitra A, Schulick RD, Tang LH, Wolfgang CL, Choti MA, Velculescu VE, Diaz LA Jr, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N.
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| Science 331(6021):1199-203. Epub 2011 Jan 20.
2011
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| 11 | MEN1, PAX2, WT1
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| Tumor suppressor menin represses paired box gene 2 expression via Wilms tumor suppressor protein-polycomb group complex.
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| Xu B, Zeng DQ, Wu Y, Zheng R, Gu L, Lin X, Hua X, Jin GH.
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| J Biol Chem 286(16):13937-44. Epub 2011 Mar 4.
2011
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| 12 | GAST, JUND, MEN1
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| Menin and JunD regulate gastrin gene expression through proximal DNA elements.
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| Mensah-Osman EJ, Veniaminova NA, Merchant JL.
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| Am J Physiol Gastrointest Liver Physiol 301(5):G783-90. doi: 10.1152/ajpgi.00160.2011. Epub 2011 Aug 18.
2011
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| 13 | MEN1
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| Menin stimulates homology-directed DNA repair.
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| Gallo A, Agnese S, Esposito I, Galgani M, Avvedimento VE.
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| FEBS Lett 584(22):4531-6. Epub 2010 Oct 20.
2010
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| 14 | CCNB2, MEN1
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| Regulation of cyclin B2 expression and cell cycle G2/m transition by menin.
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| Wu T, Zhang X, Huang X, Yang Y, Hua X.
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| J Biol Chem 285(24):18291-300. doi: 10.1074/jbc.M110.106575. Epub 2010 Apr 19.
2010
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| 15 | IQGAP1, MEN1
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| Menin interacts with IQGAP1 to enhance intercellular adhesion of beta-cells.
|
| Yan J, Yang Y, Zhang H, King C, Kan HM, Cai Y, Yuan CX, Bloom GS, Hua X.
|
| Oncogene 28(7):973-82. Epub 2008 Dec 15.
2009
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| 16 | MEN1, PPARG
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| The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation.
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| Dreijerink KM, Varier RA, van Beekum O, Jeninga EH, Höppener JW, Lips CJ, Kummer JA, Kalkhoven E, Timmers HT.
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| Mol Cell Biol 29(18):5060-9. Epub 2009 Jul 13.
2009
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| 17 | CTNNB1, MEN1
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| Nuclear-cytoplasmic shuttling of menin regulates nuclear translocation of {beta}-catenin.
|
| Cao Y, Liu R, Jiang X, Lu J, Jiang J, Zhang C, Li X, Ning G.
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| Mol Cell Biol 29(20):5477-87. Epub 2009 Aug 3.
2009
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| 18 | CCND1, MEN1
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| Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: array CGH, FISH, and tissue microarrays.
|
| Yi Y, Nowak NJ, Pacchia AL, Morrison C.
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| Genes Chromosomes Cancer 47(8):639-48.
2008
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| 19 | MEN1
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| MEN1 family with a novel frameshift mutation.
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| Nuzzo V, Tauchmanov‡ L, Falchetti A, Faggiano A, Marini F, Piantadosi S, Brandi ML, Leopaldi L, Colao A.
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| J Endocrinol Invest 29(5):450-6. 2006
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| 20 | MEN1
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| Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis.
|
| Zindy PJ, L'Helgoualc'h A, Bonnier D, Le Béchec A, Bourd-Boitin K, Zhang CX, Musso O, Glaise D, Troadec MB, Loréal O, Turlin B, Léger J, Clément B, Théret N.
|
| Hepatology 44(5):1296-307.
2006
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| 21 | FOXN3, MEN1
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| Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response.
|
| Busygina V, Kottemann MC, Scott KL, Plon SE, Bale AE.
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| Cancer Res 66(17):8397-403. Erratum in: Cancer Res. 2006 Dec 15;66(24):12039.
2006
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| 22 | KMT2A, MEN1
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| The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
|
| Yokoyama A, Somervaille TC, Smith KS, Rozenblatt-Rosen O, Meyerson M, Cleary ML.
|
| Cell 123(2):207-18. 2005
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| 23 | ASH2L, KMT2A, MEN1, RBBP5, WDR5
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| Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.
|
| Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL.
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| Proc Natl Acad Sci U S A 102(3):749-54. Epub 2005 Jan 7. 2005
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| 24 | MEN1
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| Inactivation of menin, the product of the multiple endocrine neoplasia type 1 gene, inhibits the commitment of multipotential mesenchymal stem cells into the osteoblast lineage.
|
| Sowa H, Kaji H, Canaff L, Hendy GN, Tsukamoto T, Yamaguchi T, Miyazono K, Sugimoto T, Chihara K.
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| J Biol Chem 278(23):21058-69. Epub 2003 Mar 20. Erratum in: J Biol Chem. 2004 Sep 10;279(37):39186. 2003
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| 25 | MEN1, FANCD2
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| Menin associates with FANCD2, a protein involved in repair of DNA damage.
|
| Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X.
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| Cancer Res 63(14):4204-10. 2003
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| 26 | MYH9, MEN1
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| Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain.
|
| Obungu VH, Lee Burns A, Agarwal SK, Chandrasekharapa SC, Adelstein RS, Marx SJ.
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| Oncogene 22(41):6347-58. 2003
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| 27 | MEN1
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| Functional characterization of a promoter region in the human MEN1 tumor suppressor gene.
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| Fromaget M, Vercherat C, Zhang CX, Zablewska B, Gaudray P, Chayvialle JA, Calender A, Cordier-Bussat M.
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| J Mol Biol 333(1):87-102. 2003
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| 28 | MEN1
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| Frequent occurrence of an intron 4 mutation in multiple endocrine neoplasia type 1.
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| Turner JJ, Leotlela PD, Pannett AA, Forbes SA, Bassett JH, Harding B, Christie PT, Bowen-Jones D, Ellard S, Hattersley A, Jackson CE, Pope R, Quarrell OW, Trembath R, Thakker RV.
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| J Clin Endocrinol Metab 87(6):2688-93. 2002
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| 29 | MEN1, NME1
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| Menin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23.
|
| Yaguchi H, Ohkura N, Tsukada T, Yamaguchi K.
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| J Biol Chem 277(41):38197-204. Epub 2002 Jul 26. 2002
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| 30 | MEN1
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| Involvement of the MEN1 gene locus in familial isolated hyperparathyroidism.
|
| Villablanca A, Wassif WS, Smith T, Hoog A, Vierimaa O, Kassem M, Dwight T, Forsberg L, Du Q, Learoyd D, Jones K, Stranks S, Juhlin C, Teh BT, Carling T, Robinson B, Larsson C.
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| Eur J Endocrinol 147(3):313-22. 2002
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| 31 | SMAD3, MEN1
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| Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling.
|
| Kaji H, Canaff L, Lebrun JJ, Goltzman D, Hendy GN.
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| Proc Natl Acad Sci U S A 98(7):3837-42. 2001
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| 32 | MEN1, NF2
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| Molecular genetic alterations on chromosomes 11 and 22 in ependymomas.
|
| Lamszus K, Lachenmayer L, Heinemann U, Kluwe L, Finckh U, Hoppner W, Stavrou D, Fillbrandt R, Westphal M.
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| Int J Cancer 91(6):803-8. 2001
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| 33 | MEN1, NEM1
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| Menin, a gene product responsible for multiple endocrine neoplasia type 1, interacts with the putative tumor metastasis suppressor nm23.
|
| Ohkura N, Kishi M, Tsukada T, Yamaguchi K.
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| Biochem Biophys Res Commun 282(5):1206-10. 2001
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| 34 | MEN1
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| Loss of heterozygosity of the MEN1 gene in a large series of TSH-secreting pituitary adenomas.
|
| Asteria C, Anagni M, Persani L, Beck-Peccoz P.
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| J Endocrinol Invest 24(10):796-801. 2001
|
| 35 | MEN1
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| Familial isolated primary hyperparathyroidism--a multiple endocrine neoplasia type 1 variant?
|
| Miedlich S, Lohmann T, Schneyer U, Lamesch P, Paschke R.
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| Eur J Endocrinol 145(2):155-60. Review. 2001
|
| 36 | MEN1
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| MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinoma.
|
| Debelenko LV, Swalwell JI, Kelley MJ, Brambilla E, Manickam P, Baibakov G, Agarwal SK, Spiegel AM, Marx SJ, Chandrasekharappa SC, Collins FS, Travis WD, Emmert-Buck MR.
|
| Genes Chromosomes Cancer 28(1):58-65. 2000
|
| 37 | MEN1
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| A novel mutation of the MEN1 gene in a Japanese kindred with familial isolated primary hyperparathyroidism.
|
| Honda M, Tsukada T, Tanaka H, Maruyama K, Yamaguchi K, Obara T, Yamaji T, Ishibashi M.
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| Eur J Endocrinol 142(2):138-43. 2000
|
| 38 | MEN1
|
| Characterization of high-grade neuroendocrine tumors of the lung in relation to menin mutations.
|
| Haruki N, Yatabe Y, Travis WD, Nomoto S, Osada H, Nakamura S, Nakao A, Fujii Y, Takahashi T.
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| Jpn J Cancer Res 91(3):317-23. 2000
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| 39 | MEN1
|
| MEN1 gene mutation analysis of sporadic adrenocortical lesions.
|
| Gortz B, et al.
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| Int J Cancer 80(3):373-9. 1999
|
| 40 | MEN1
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| Germline mutations in the multiple endocrine neoplasia type 1 gene: evidence for frequent splicing defects.
|
| Mutch MG, et al.
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| Hum Mutat 13(3):175-85. 1999
|
| 41 | JUND, MEN1
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| Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription.
|
| Agarwal SK, et al.
|
| Cell 96(1):143-52. 1999
|
| 42 | MEN1
|
| Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms.
|
| Gortz B, et al.
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| Am J Pathol 154(2):429-36. 1999
|
| 43 | BRMS1, MEN1
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| Sporadic follicular thyroid tumors show loss of a 200-kb region in 11q13 without evidence for mutations in the MEN1 gene.
|
| Nord B, et al.
|
| Genes Chromosomes Cancer 26(1):35-9. 1999
|
| 44 | MEN1
|
| Genetic and clinical analysis in 10 Spanish patients with multiple endocrine neoplasia type 1.
|
| Cebrian A, et al.
|
| Eur J Hum Genet 7(5):585-9. 1999
|
| 45 | MEN1
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| A novel splicing mutation (894-9 G --> A) of the MEN1 gene responsible for multiple endocrine neoplasia type 1.
|
| Kishi M, et al.
|
| Cancer Lett 142(1):105-10 1999
|
| 46 | MEN1
|
| Calcitonin receptor antibodies in the identification of osteoclasts.
|
| Quinn JM, et al.
|
| Bone 25(1):1-8 1999
|
| 47 | MEN1
|
| Menin represses JunD-activated transcription by a histone deacetylase-dependent mechanism.
|
| Gobl AE, Berg M, Lopez-Egido JR, Oberg K, Skogseid B, Westin G.
|
| Biochim Biophys Acta 1447(1):51-6 1999
|
| 48 | MEN1
|
| Characterization of the MEN1 gene product, menin, by site-specific polyclonal antibodies.
|
| Ikeo Y, Sakurai A, Hashizume K.
|
| Jpn J Cancer Res 90(10):1088-95 1999
|
| 49 | CAPN1, MEN1, MAP4K2, VEGFB, NRXN2
|
| A 500-kb sequence-ready cosmid contig and transcript map of the MEN1 region on 11q13.
|
| Bergman L, Silins G, Grimmond S, Hummerich H, Stewart C, Little P, Hayward N.
|
| Genomics 55(1):49-56. 1999
|
| 50 | MEN1
|
| Menin, the product of the MEN1 gene, is a nuclear protein.
|
| Guru SC, et al.
|
| Proc Natl Acad Sci U S A 95 : 1630-1634. 1998
|
| 51 | MEN1
|
| Characterization of mutations in patients with multiple endocrine neoplasia type 1.
|
| Bassett JH, Forbes SA, Pannett AA, Lloyd SE, Christie PT, Wooding C, Harding B, Besser GM, Edwards CR, Monson JP, Sampson J, Wass JA, Wheeler MH, Thakker RV.
|
| Am J Hum Genet 62(2):232-44. 1998
|
| 52 | MEN1
|
| Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families.
|
| Agarwal SK, et al.
|
| Hum Mutat 12 : 75-82. 1998
|
| 53 | MEN1
|
| Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism.
|
| Teh BT, et al.
|
| J Clin Endocrinol Metab 83 : 2621-2626. 1998
|
| 54 | BRMS1, MEN1
|
| Analysis of loss of heterozygosity on chromosome 11 and infrequent inactivation of the MEN1 gene in sporadic pituitary adenomas.
|
| Tanaka C, Kimura T, Yang P, Moritani M, Yamaoka T, Yamada S, Sano T, Yoshimoto K, Itakura M.
|
| J Clin Endocrinol Metab 83 : 2631-2634. 1998
|
| 55 | MEN1
|
| A family with isolated hyperparathyroidism segregating a missense MEN1 mutation and showing loss of the wild-type alleles in the parathyroid tumors.
|
| Teh BT, et al.
|
| Am J Hum Genet 63 : 1544-1549. 1998
|
| 56 | MEN1
|
| A novel germline mutation in exon 5 of the multiple endocrine neoplasia type 1 gene.
|
| Chico A, Gallart L, Mato E, Mayoral C, Martin-Campos JM, Catasus L, Rodriguez-Espinosa J, Matias-Guiu X, Blanco-Vaca F, de Leiva A.
|
| J Mol Med 76 : 837-839. 1998
|
| 57 | MEN1
|
| MEN1 gene mutations in 12 MEN1 families and their associated tumors.
|
| Bartsch D, Kopp I, Bergenfelz A, Rieder H, Munch K, Jager K, Deiss Y, Schudy A, Barth P, Arnold R, Rothmund M, Simon B.
|
| Eur J Endocrinol 139 : 416-420. 1998
|
| 58 | MEN1, PLCB3
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| Exclusion of the posphoinositide-specific phospholipase Cbeta3 (PLCB3) gene as a candidate for multiple endocrine neoplasia type 1.
|
| Weber G, et al.
|
| Hum Genet 99 : 130-132. 1997
|
| 59 | MEN1, PLCB3
|
| Exclusion of the phosphatidylinositol-specific phospholipase C beta3 (PLC beta3) gene as candidate for the multiple endocrine neoplasia type 1 (MEN 1) gene.
|
| De Wit MJ, et al.
|
| Hum Genet 99 : 133-137. 1997
|
| 60 | MEN1
|
| Positional cloning of the gene for multiple endocrine neoplasia-type 1.
|
| Chandrasekharappa SC, et al.
|
| Science 276 : 404-407. 1997
|
| 61 | BRMS1, MEN1
|
| Loss of heterozygosity at 11q13 : analysis of pituitary tumors, lung carcinoids, lipomas, and other uncommon tumors in subjects with familial multiple endocrine neoplasia type 1.
|
| Dong Q, et al.
|
| J Clin Endocrinol Metab 82 : 1416-1420. 1997
|
| 62 | BRMS1, MEN1
|
| Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis.
|
| Emmert-Buck MR, Lubensky IA, Dong Q, Manickam P, Guru SC, Kester MB, Olufemi SE, Agarwal S, Burns AL, Spiegel AM, Collins FS, Marx SJ, Zhuang Z, Liotta LA, Chandrasekharappa SC, Debelenko LV.
|
| Cancer Res 57(10):1855-8. 1997
|
| 63 | MEN1
|
| Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states.
|
| Agarwal SK, Kester MB, Debelenko LV, Heppner C, Emmert-Buck MR, Skarulis MC, Doppman JL, Kim YS, Lubensky IA, Zhuang Z, Green JS, Guru SC, Manickam P, Olufemi SE, Liotta LA, Chandrasekharappa SC, Collins FS, Spiegel AM, Burns AL, Marx SJ.
|
| Hum Mol Genet 6(7):1169-75. 1997
|
| 64 | MEN1, ANG2, ANG3, MRPL49, ZNHIT2, C11orf6, FAU
|
| Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.
|
| Lemmens I, Van de Ven WJ, Kas K, Zhang CX, Giraud S, Wautot V, Buisson N, De Witte K, Salandre J, Lenoir G, Pugeat M, Calender A, Parente F, Quincey D, Gaudray P, De Wit MJ, Lips CJ, Hoppener JW, Khodaei S, Grant AL, Weber G, Kytola S, Teh BT, Farnebo F, Thakker RV, et al.
|
| Hum Mol Genet 6(7):1177-83. 1997
|
| 65 | MEN1
|
| A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13.
|
| Guru SC, Olufemi SE, Manickam P, Cummings C, Gieser LM, Pike BL, Bittner ML, Jiang Y, Chinault AC, Nowak NJ, Brzozowska A, Crabtree JS, Wang Y, Roe BA, Weisemann JM, Boguski MS, Agarwal SK, Burns AL, Spiegel AM, Marx SJ, Flejter WL, de Jong PJ, Collins FS, Chandrasekharappa SC.
|
| Genomics 42(3):436-45. 1997
|
| 66 | CAPN1, FAU, KAT5, MAP3K11, MEN1, PABYL, PLCB3, PYGM, RELA, SEA, SF1, SIPA1
|
| A transcript map encompassing the multiple endocrine neoplasia type-1 (MEN1) locus on chromosome 11q13.
|
| Sawicki M, Arnold E, Ebrahimi S, Duell T, Jin S, Wood T, Chakrabarti R, Peters J, Wan Y, Samara G, Weier HU, Udar N, Passaro E Jr, Srivatsan ES.
|
| Genomics 42(3):405-12. 1997
|
| 67 | ANG2, ANG3, ARL2, C11orf6, MEN1, MRPL49, NON, PPP1R14B, PPP2R5B, TM7SF2, VEGFA
|
| Construction of a 1.2-Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.
|
| Lemmens I, Merregaert J, Van de Ven WJ, Kas K, Zhang CX, Giraud S, Wautot V, Buisson N, De Witte K, Salandre J, Lenoir G, Calender A, Parente F, Quincey D, Courseaux A, Carle GF, Gaudray P, De Wit MJ, Lips CJ, Hoppener JW, Khodaei S, Grant AL, Weber G, Kytola S, Thakker RV, et al.
|
| Genomics 44(1):94-100. 1997
|
| 68 | MEN1
|
| Linkage disequilibrium studies in multiple endocrine neoplasia type 1 (MEN1).
|
| The European Consortium on MEN1.
|
| Hum Genet 100(5-6):657-65. 1997
|
| 69 | RASGRP2, CDC42BPG, PYGM, MEN1, SF1
|
| The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13.
|
| Kedra D, Seroussi E, Fransson I, Trifunovic J, Clark M, Lagercrantz J, Blennow E, Mehlin H, Dumanski J.
|
| Hum Genet 100(5-6):611-9. 1997
|
| 70 | BBS1, MS4A1, MEN1, SCA5
|
| A 3-Mb sequence-ready contig map encompassing the multiple disease gene cluster on chromosome 11q13.1-q13.3.
|
| Kitamura E, Hosoda F, Fukushima M, Asakawa S, Shimizu N, Imai T, Soeda E, Ohki M.
|
| DNA Res 4(4):281-9. 1997
|
| 71 | MEN1
|
| Mutations in the MEN I gene in sporadic neuroendocrine tumours of gastroenteropancreatic system.
|
| Toliat MR, et al.
|
| Lancet 350 : 1223. 1997
|
| 72 | MEN1
|
| Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung.
|
| Debelenko LV, Brambilla E, Agarwal SK, Swalwell JI, Kester MB, Lubensky IA, Zhuang Z, Guru SC, Manickam P, Olufemi SE, Chandrasekharappa SC, Crabtree JS, Kim YS, Heppner C, Burns AL, Spiegel AM, Marx SJ, Liotta LA, Collins FS, Travis WD, Emmert-Buck MR.
|
| Hum Mol Genet 6(13):2285-90. 1997
|
| 73 | EHD1, ZFPL1, MEN1, NRXN2, SNX9, SNX15, DPF2
|
| A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus.
|
| Guru SC, Agarwal SK, Manickam P, Olufemi SE, Crabtree JS, Weisemann JM, Kester MB, Kim YS, Wang Y, Emmert-Buck MR, Liotta LA, Spiegel AM, Boguski MS, Roe BA, Collins FS, Marx SJ, Burns L, Chandrasekharappa SC.
|
| Genome Res 7(7):725-35. 1997
|
| 74 | MEN1, CAPN1
|
| Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene.
|
| Pang JT, et al.
|
| Hum Genet 97 : 732-741. 1996
|
| 75 | FAU, MEN1
|
| Definition of the minimal MEN1 candidate area based on a 5-Mb integrated map of proximal 11q13.
|
| Courseaux A, et al.
|
| Genomics 37 : 354-365. 1996
|
| 76 | BRMS1, MEN1
|
| Carcinoid tumors frequently display genetic abnormalities involving chromosome 11.
|
| Jakobovitz O, et al.
|
| J Clin Endocrinol Metab 81 : 3164-3167. 1996
|
| 77 | BRMS1, MEN1
|
| Clonal analysis by chromosome 11 microsatellite-PCR of microdissected parathyroid tumors from MEN1 patients.
|
| Morelli A, et al.
|
| Biochem Biophys Res Commun 227 : 736-742. 1996
|
| 78 | MEN1
|
| A 1.5-megabase physical map encompassing the multiple endocrine neoplasia type-1 (MEN1) locus on chromosome 11q13.
|
| Wood TF, et al.
|
| Genomics 38 : 166-173. 1996
|
| 79 | MEN1
|
| Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients.
|
| Lubensky IA, et al.
|
| Cancer Res 56 : 5272-5278. 1996
|
| 80 | D11S1961, MEN1
|
| Mapping eight new polymorphisms in 11q13 in the vicinity of multiple endocrine neoplasia type 1 : identification of a new distal recombinant.
|
| Smith CM, et al.
|
| Hum Genet 96 : 377-387. 1995
|
| 81 | MEN1
|
| Genetic mapping of the multiple endocrine neoplasia type 1 locus at 11q13.
|
| Teh BT, et al.
|
| J Int Med 238 : 249-253. 1995
|
| 82 | MEN1, PLCB3
|
| Candidate genes for multiple endocrine neoplasia type 1.
|
| Lagercrantz J, et al.
|
| J Int Med 238 : 245-248. 1995
|
| 83 | MEN1, FKBP2
|
| Exclusion of the 13-kDa rapamycin binding protein gene (FKBP2) as a candidate gene for multiple endocrine neoplasia type 1.
|
| Grimmond S, et al.
|
| Hum Genet 95 : 455-458. 1995
|
| 84 | MEN1
|
| Mapping the gene for hereditary hyperparathyroidism and prolactinoma (MENI Burin) to chromosome 11q : evidence for a founder effect in patients from Newfoundland.
|
| Petty EM, et al.
|
| Am J Hum Genet 54 : 1060-1066. 1994
|
| 85 | MEN1, PLCB3
|
| The phospholipase C beta3 gene located in the MEN1 region shows loss of expression in endocrine tumours.
|
| Weber G, et al.
|
| Hum Mol Genet 3 : 1775-1781. 1994
|
| 86 | MEN1
|
| Fine-scale mapping of the gene responsible for multiple endocrine neoplasia type I (MENI).
|
| Fujimori M, et al.
|
| Am J Hum Genet 50 : 399-403. 1992
|
| 87 | MEN1
|
| Predictive testing for multiple endocrine neoplasia type 1 using DNA polymorphisms.
|
| Larsson C, et al.
|
| J Clin Invest 89 : 1344-1349. 1992
|
| 88 | MEN1
|
| Isolation and mapping of polymorphic cosmid clones used for sublocalization of the multiple endocrine neoplasia type 1 (MEN1) locus.
|
| Larsson C, et al.
|
| Hum Genet 89 : 187-193. 1992
|
| 89 | MEN1
|
| Cytogenetics of multiple endocrine neoplasia syndrome. II.-Chromosome abnormalities in an insulinoma and a glucagonoma from two subjects with MEN1.
|
| Scappaticci S, et al.
|
| Cancer Genet Cytogenet 63 : 17-21. 1992
|
| 90 | MEN1
|
| No evidence for linkage heterogeneity in multiple endocrine neoplasia type I.
|
| Amos CI, et al.
|
| (HGM11) Cytogenet Cell Genet 58 : 1954. 1991
|
| 91 | MEN1
|
| Physical mapping of chromosome 11q12-13 by pulsed field gel electrophoresis.
|
| Gailani MR, et al.
|
| (HGM11) Cytogenet Cell Genet 58 : 1959. 1991
|
| 92 | MEN1
|
| Chromosome 11 abnormalities in somatotrophinomas from patients with acromegaly.
|
| Thakker RV, et al.
|
| (HGM11) Cytogenet Cell Genet 58 : 1971. 1991
|
| 93 | MEN1
|
| Linkage and physical mapping of the MEN1 region on 11q13.
|
| Janson M, et al.
|
| (HGM11) Cytogenet Cell Genet 58 : 1964. 1991
|
| 94 | BCL1, MEN1
|
| A radiation hybrid map of the proximal long arm of human chromosome 11 containing the multiple endocrine neoplasia type 1 (MEN-1) and bcl-1 disease loci.
|
| Richard CW, et al.
|
| Am J Hum Genet 49 : 1189-1196. 1991
|
| 95 | MEN1
|
| Detailed physical map of human chromosomal region 11q12-13 shows high meiotic recombination rate around the MEN1 locus.
|
| Janson M, et al.
|
| Proc Natl Acad Sci U S A 88 : 10609-10613. 1991
|
| 96 | MEN1
|
| Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1.
|
| Bale AE, et al.
|
| Cancer Res 51 : 1154-1157. 1991
|
| 97 | MEN1
|
| Clinical phenotype and linkage analysis of a prolactinoma variant of multiple endocrine neoplasia, type 1 (MEN-1 BURIN).
|
| Green JS, et al.
|
| Am J Hum Genet 47 : A218. 1990
|
| 98 | MEN1
|
| Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.
|
| Bystršm C, et al.
|
| Proc Natl Acad Sci U S A 87 : 1968-1972. 1990
|
| 99 | MEN1
|
| Chromosome 11 allele loss in sporadic insulinoma.
|
| Patel P, et al.
|
| J Clin Pathol 43 : 377-378. 1990
|
| 100 | MEN1
|
| Localization of the genetic defect in multiple endocrine neoplasia type 1 within a small region of chromosome 11.
|
| Nakamura Y, Larsson C, Julier C, Bystrom C, Skogseid B, Wells S, Oberg K, Carlson M, Taggart T, O'Connell P, et al.
|
| Am J Hum Genet 44(5):751-5. 1989
|
| 101 | MEN1
|
| Clonality of parathyroid tumors in familial multiple endocrine neoplasia type 1.
|
| Friedman E, Sakaguchi K, Bale AE, Falchetti A, Streeten E, Zimering MB, Weinstein LS, McBride WO, Nakamura Y, Brandi ML, et al.
|
| N Engl J Med 321 : 213-218. 1989
|
| 102 | FGF3, MEN1
|
| Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11.
|
| Thakker RV, et al.
|
| N Engl J Med 321 : 218-224. 1989
|
| 103 | MEN1
|
| Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
|
| Larsson C, et al.
|
| Nature 332 : 85-87. 1988
|
| 104 | MEN1
|
| Multiple endocrine neoplasia type 1 (MEN1) : genetic linkage studies.
|
| Bale SJ, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 575. 1987
|
| 105 | MEN1
|
| Prolactinomas in familial multiple endocrine neoplasia syndrome type 1. Relationship to HLA and carcinoid tumors.
|
| Farid NR, et al.
|
| Am J Med 69 : 874-880. 1980
|