| 1 | DYRK1A, MEF2D
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| DYRK1A phosphorylates MEF2D and decreases its transcriptional activity
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| Wang P, Zhao J, Sun X.
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| J Cell Mol Med. Jun 9;25(13):6082–93. doi: 10.1111/jcmm.16505. Epub ahead of print. 2021
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| 2 | MEF2D
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| Overexpression and biological function of MEF2D in human pancreatic cancer.
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| Song Z, Feng C, Lu Y, Gao Y, Lin Y, Dong C.
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| Am J Transl Res 9(11):4836-4847. eCollection 2017.
2017
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| 3 | MEF2D, ZBTB7A
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| Pokemon promotes the invasiveness of hepatocellular carcinoma by enhancing MEF2D transcription.
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| Kong J, Liu X, Li X, Wu J, Wu N, Chen J, Fang F.
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| Hepatol Int 10(3):493-500. doi: 10.1007/s12072-015-9697-y. Epub 2016 Jan 21.
2016
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| 4 | MEF2C, MEF2D
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| Essential control of early B-cell development by Mef2 transcription factors.
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| Herglotz J, Unrau L, Hauschildt F, Fischer M, Kriebitzsch N, Alawi M, Indenbirken D, Spohn M, Müller U, Ziegler M, Schuh W, Jäck HM, Stocking C.
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| Blood 127(5):572-81. doi: 10.1182/blood-2015-04-643270. Epub 2015 Dec 10.
2016
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| 5 | IGF1, MEF2D
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| The involvement of myocyte enhancer factor 2D in regulating tumor biology of cardiac myxoma.
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| Huo Y, Zhao Q, Wang C, Zhao F, Du Y, Sun W.
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| Tumour Biol 37(4):5405-11. doi: 10.1007/s13277-015-4386-y. Epub 2015 Nov 12.
2016
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| 6 | MEF2D, RBFOX1, RBFOX2
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| Rbfox proteins regulate tissue-specific alternative splicing of Mef2D required for muscle differentiation.
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| Runfola V, Sebastian S, Dilworth FJ, Gabellini D.
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| J Cell Sci 128(4):631-7. doi: 10.1242/jcs.161059. Epub 2015 Jan 20.
2015
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| 7 | MEF2D, PTEN
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| MEF2D deficiency in neonatal cardiomyocytes triggers cell cycle re-entry and programmed cell death in vitro.
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| Estrella NL, Clark AL, Desjardins CA, Nocco SE, Naya FJ.
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| J Biol Chem 290(40):24367-80. doi: 10.1074/jbc.M115.666461. Epub 2015 Aug 20.
2015
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| 8 | MEF2D, ZBTB7A
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| Pokemon and MEF2D co-operationally promote invasion of hepatocellular carcinoma.
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| Hong X, Hong XY, Li T, He CY.
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| Tumour Biol 36(12):9885-93. doi: 10.1007/s13277-015-3744-0. Epub 2015 Jul 13.
2015
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| 9 | IL10, MEF2D
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| Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death.
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| Yang S, Gao L, Lu F, Wang B, Gao F, Zhu G, Cai Z, Lai J, Yang Q.
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| J Neuroinflammation 12:33. doi: 10.1186/s12974-015-0258-z.
2015
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| 10 | CRX, MEF2D
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| MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers.
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| Andzelm MM, Cherry TJ, Harmin DA, Boeke AC, Lee C, Hemberg M, Pawlyk B, Malik AN, Flavell SW, Sandberg MA, Raviola E, Greenberg ME.
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| Neuron 86(1):247-63. doi: 10.1016/j.neuron.2015.02.038. Epub 2015 Mar 19.
2015
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| 11 | ARR3, CACNA1S, CRX, GUCA1B, MEF2D, PDE6H
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| Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells.
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| Omori Y, Kitamura T, Yoshida S, Kuwahara R, Chaya T, Irie S, Furukawa T.
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| Genes Cells 20(5):408-26. doi: 10.1111/gtc.12233. Epub 2015 Mar 11. 2015
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| 12 | MEF2D, RBFOX2, ROCK2
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| Rbfox2-Coordinated Alternative Splicing of Mef2d and Rock2 Controls Myoblast Fusion during Myogenesis.
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| Singh RK, Xia Z, Bland CS, Kalsotra A, Scavuzzo MA, Curk T, Ule J, Li W, Cooper TA.
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| Mol Cell 55(4):592-603. doi: 10.1016/j.molcel.2014.06.035. Epub 2014 Jul 31.
2014
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| 13 | ATM, MEF2D
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| ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage.
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| Chan SF, Sances S, Brill LM, Okamoto S, Zaidi R, McKercher SR, Akhtar MW, Nakanishi N, Lipton SA.
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| J Neurosci 34(13):4640-53. doi: 10.1523/JNEUROSCI.2510-12.2014.
2014
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| 14 | MEF2A, MEF2C, MEF2D
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| Requirement of MEF2A, C, and D for skeletal muscle regeneration.
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| Liu N, Nelson BR, Bezprozvannaya S, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN.
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| Proc Natl Acad Sci U S A 111(11):4109-14. doi: 10.1073/pnas.1401732111. Epub 2014 Mar 3.
2014
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| 15 | MEF2D
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| Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease.
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| Gao L, She H, Li W, Zeng J, Zhu J, Jones DP, Mao Z, Gao G, Yang Q.
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| Antioxid Redox Signal 20(18):2936-48. doi: 10.1089/ars.2013.5399. Epub 2014 Feb 3.
2014
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| 16 | MEF2D
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| Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation.
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| Choi J, Jang H, Kim H, Lee JH, Kim ST, Cho EJ, Youn HD.
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| Nucleic Acids Res 42(1):224-34. doi: 10.1093/nar/gkt873. Epub 2013 Sep 27.
2014
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| 17 | MEF2D, MYOG
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| Requirement of decreased O-GlcNAc glycosylation of Mef2D for its recruitment to the myogenin promoter.
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| Ogawa M, Sakakibara Y, Kamemura K.
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| Biochem Biophys Res Commun 433(4):558-62. doi: 10.1016/j.bbrc.2013.03.033. Epub 2013 Mar 22.
2013
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| 18 | MEF2A, MEF2C, MEF2D
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| In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival.
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| Akhtar MW, Kim MS, Adachi M, Morris MJ, Qi X, Richardson JA, Bassel-Duby R, Olson EN, Kavalali ET, Monteggia LM.
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| PLoS One 7(4):e34863. doi: 10.1371/journal.pone.0034863. Epub 2012 Apr 9.
2012
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| 19 | MEF2D
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| α-synuclein aggregation reduces nigral myocyte enhancer factor-2D in idiopathic and experimental Parkinson's disease.
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| Chu Y, Mickiewicz AL, Kordower JH.
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| Neurobiol Dis 41(1):71-82. doi: 10.1016/j.nbd.2010.08.022. Epub 2010 Sep 9.
2011
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| 20 | HDAC1, MEF2A, MEF2D
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| Dual roles for MEF2A and MEF2D during human macrophage terminal differentiation and c-Jun expression.
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| Aude-Garcia C, Collin-Faure V, Bausinger H, Hanau D, Rabilloud T, Lemercier C.
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| Biochem J 430(2):237-44. 2010
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| 21 | MEF2D
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| Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy.
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| Yang Q, She H, Gearing M, Colla E, Lee M, Shacka JJ, Mao Z.
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| Science 323(5910):124-7.
2009
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| 22 | GSK3B, MEF2D
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| Phosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis.
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| Wang X, She H, Mao Z.
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| J Biol Chem 284(47):32619-26. Epub 2009 Sep 29.PMID: 19801631 2009
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| 23 | MEF2D
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| The complexity in regulation of MEF2D by chaperone-mediated autophagy.
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| Yang Q, Mao Z.
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| Autophagy 5(7):1073-4. Epub 2009 Oct 15.PMID: 19738442 2009
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| 24 | MEF2D
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| Protein kinase A represses skeletal myogenesis by targeting myocyte enhancer factor 2D.
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| Du M, Perry RL, Nowacki NB, Gordon JW, Salma J, Zhao J, Aziz A, Chan J, Siu KW, McDermott JC.
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| Mol Cell Biol 28(9):2952-70. Epub 2008 Feb 25.PMID: 18299387 2008
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| 25 | MEF2D
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| Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection.
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| Flavell SW, Kim TK, Gray JM, Harmin DA, Hemberg M, Hong EJ, Markenscoff-Papadimitriou E, Bear DM, Greenberg ME.
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| Neuron 60(6):1022-38.PMID: 19109909 2008
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| 26 | CABIN1, MEF2A, MEF2B, MEF2C, MEF2D, SUV39H1
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| Cabin1 represses MEF2 transcriptional activity by association with a methyltransferase, SUV39H1.
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| Jang H, Choi DE, Kim H, Cho EJ, Youn HD.
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| J Biol Chem 282(15):11172-9. Epub 2006 Dec 17. 2007
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| 27 | ATXN1, HDAC4, MEF2A, MEF2B, MEF2C, MEF2D
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| The neurodegenerative disease protein ataxin-1 antagonizes the neuronal survival function of myocyte enhancer factor-2.
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| Bolger TA, Zhao X, Cohen TJ, Tsai CC, Yao TP.
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| J Biol Chem 282(40):29186-92. Epub 2007 Jul 23. 2007
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| 28 | MEF2D
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| MEF2D expression increases during neuronal differentiation of neural progenitor cells and correlates with neurite length.
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| Lam BY, Chawla S.
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| Neurosci Lett 427(3):153-8. Epub 2007 Sep 21.PMID: 17945419 2007
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| 29 | MEF2A, MEF2C, MEF2D
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| Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.
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| Zhu B, Ramachandran B, Gulick T.
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| J Biol Chem 280(31):28749-60. Epub 2005 Apr 15. 2005
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| 30 | DAZAP1, MEF2D
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| Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia.
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| Prima V, Gore L, Caires A, Boomer T, Yoshinari M, Imaizumi M, Varella-Garcia M, Hunger SP.
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| Leukemia 19(5):806-13. 2005
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| 31 | MEF2A, MEF2B, MEF2C, MEF2D, NFATC2
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| Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT).
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| Pan F, Ye Z, Cheng L, Liu JO.
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| J Biol Chem 279(15):14477-80. Epub 2004 Jan 13. 2004
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| 32 | DAZAP1, MEF2D
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| Identification of a novel fusion gene in a pre-B acute lymphoblastic leukemia with t(1;19)(q23;p13).
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| Yuki Y, Imoto I, Imaizumi M, Hibi S, Kaneko Y, Amagasa T, Inazawa J.
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| Cancer Sci 95(6):503-7. 2004
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| 33 | EMB, EP300, MEF2D
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| A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300.
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| Molinari S, Relaix F, Lemonnier M, Kirschbaum B, Schäfer B, Buckingham M.
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| Mol Cell Biol 24(7):2944-57.
2004
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| 34 | MEF2D
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| 14-3-3tau associates with and activates the MEF2D transcription factor during muscle cell differentiation.
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| Choi SJ, Park SY, Han TH.
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| Nucleic Acids Res 29(13):2836-42. 2001
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| 35 | MEF2A, MEF2B, MEF2C, MEF2D
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| Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.
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| Hobson GM, Krahe R, Garcia E, Siciliano MJ, Funanage VL.
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| Genomics 29(3):704-11. 1995
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| 36 | MEF2D
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| A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage.
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| Breitbart RE, Liang CS, Smoot LB, Laheru DA, Mahdavi V, Nadal-Ginard B.
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| Development 118(4):1095-106. 1993
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| 37 | MEF2A, MEF2B, MEF2C, MEF2D
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| A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes.
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| Gossett LA, Kelvin DJ, Sternberg EA, Olson EN.
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| Mol Cell Biol 9(11):5022-33. 1989
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