| 1 | MED17, MICCH
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| Infantile cerebral and cerebellar atrophy is associated with a mutation in the MED17 subunit of the transcription preinitiation mediator complex.
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| Kaufmann R, Straussberg R, Mandel H, Fattal-Valevski A, Ben-Zeev B, Naamati A, Shaag A, Zenvirt S, Konen O, Mimouni-Bloch A, Dobyns WB, Edvardson S, Pines O, Elpeleg O.
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| Am J Hum Genet 87(5):667-70. Epub 2010 Oct 14.PMID: 20950787 2010
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| 2 | MED17, RELA
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| Two modes of transcriptional activation at native promoters by NF-kappaB p65.
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| van Essen D, Engist B, Natoli G, Saccani S.
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| PLoS Biol 7(3):e73.PMID: 19338389 2009
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| 3 | MED11, MED17, MED22
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| Mediator-dependent recruitment of TFIIH modules in preinitiation complex.
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| Esnault C, Ghavi-Helm Y, Brun S, Soutourina J, Van Berkum N, Boschiero C, Holstege F, Werner M.
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| Mol Cell 31(3):337-46.PMID: 18691966 2008
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| 4 | CDK8, MED1, MED17
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| CDK8 is a stimulus-specific positive coregulator of p53 target genes.
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| Donner AJ, Szostek S, Hoover JM, Espinosa JM.
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| Mol Cell 27(1):121-33. 2007
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| 5 | MED17, MED19
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| Mediator as a general transcription factor.
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| Takagi Y, Kornberg RD.
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| J Biol Chem 281(1):80-9. Epub 2005 Nov 1.PMID: 16263706 2006
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| 6 | MED17
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| Head module control of mediator interactions.
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| Takagi Y, Calero G, Komori H, Brown JA, Ehrensberger AH, Hudmon A, Asturias F, Kornberg RD.
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| Mol Cell 23(3):355-64.PMID: 16885025 2006
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| 7 | MED17
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| The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
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| Jang MK, Mochizuki K, Zhou M, Jeong HS, Brady JN, Ozato K.
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| Mol Cell 19(4):523-34. 2005
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| 8 | CDK19, MED10, MED11, MED13L, MED13L, MED14, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED26, MED26, MED27, MED28, MED29, MED29, MED29, MED30, MED6, MED7, MED9
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| A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.
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| Sato S, Tomomori-Sato C, Parmely TJ, Florens L, Zybailov B, Swanson SK, Banks CA, Jin J, Cai Y, Washburn MP, Conaway JW, Conaway RC.
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| Mol Cell 14(5):685-91. 2004
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| 9 | MED11, MED9, MED17, MED29, MED14, MED26, MED7, MED16, MED21, MED27
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| A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.
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| Tomomori-Sato C, Sato S, Parmely TJ, Banks CA, Sorokina I, Florens L, Zybailov B, Washburn MP, Brower CS, Conaway RC, Conaway JW.
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| J Biol Chem 279(7):5846-51. Epub 2003 Nov 24. 2004
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| 10 | MED19, MED4, MED22, MED10, MED6, MED11, MED23, MED17, MED29, MED14, MED26, MED7, MED16, MED20, MED21, MED27
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| A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.
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| Sato S, Tomomori-Sato C, Banks CA, Parmely TJ, Sorokina I, Brower CS, Conaway RC, Conaway JW.
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| J Biol Chem 278(50):49671-4. Epub 2003 Oct 22. 2003
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| 11 | MED14 , MED23, MED17, MED26, MED27, MED7, MED1
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| The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.
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| Ryu S, Zhou S, Ladurner AG, Tjian R.
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| Nature 397(6718):446-50. 1999
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| 12 | THRAP4, MED13, MED16, MED30, MED13L, THRAP3, MED17, MED1, MED12, MED4
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| Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.
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| Ito M, Yuan CX, Malik S, Gu W, Fondell JD, Yamamura S, Fu ZY, Zhang X, Qin J, Roeder RG.
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| Mol Cell 3(3):361-70. 1999
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| 13 | MED16, MED23, MED17, MED4
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| Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.
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| Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Naar AM, Erdjument-Bromage H, Tempst P, Freedman LP.
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| Nature 398(6730):824-8. 1999
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