1 | MC3R, MC4R
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| Biased signaling at neural melanocortin receptors in regulation of energy homeostasis.
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| Yang LK, Tao YX.
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| Biochim Biophys Acta iochim Biophys Acta. 2017 Apr 19. pii: S0925-4439(17)30122-9. doi: 10.1016/j.bbadis.2017.04.010. [Epub ahead of print]
2017
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2 | MC3R, MC4R, RNF11
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| Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.
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| Müller A, Niederstadt L, Jonas W, Yi CX, Meyer F, Wiedmer P, Fischer J, Grötzinger C, Schürmann A, Tschöp M, Kleinau G, Grüters A, Krude H, Biebermann H.
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| Front Endocrinol (Lausanne) 7:109. doi: 10.3389/fendo.2016.00109. eCollection 2016.
2016
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3 | MC3R, MC4R
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| Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats.
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| You P, Hu H, Chen Y, Zhao Y, Yang Y, Wang T, Xing R, Shao Y, Zhang W, Li D, Chen H, Liu M.
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| Sci Rep 6:34938. doi: 10.1038/srep34938.
2016
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4 | MC3R
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| Functions of DPLIY motif and helix 8 of human melanocortin-3 receptor.
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| Yang Z, Huang ZL, Tao YX.
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| J Mol Endocrinol 55(2):107-17. doi: 10.1530/JME-15-0116. Epub 2015 Jul 28.
2015
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5 | MC3R
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| Functional characterization of the mouse melanocortin 3 receptor gene promoter.
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| Okutsu K, Ojima F, Shinohara N, Taniuchi S, Mizote Y, Aoki K, Kudo T, Ogoshi M, Takeuchi S, Takahashi S.
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| Gene 562(1):62-9. doi: 10.1016/j.gene.2015.02.043. Epub 2015 Feb 17.
2015
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6 | MC3R
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| Evaluation of hypothalamic murine and human melanocortin 3 receptor transcript structure.
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| Taylor-Douglas DC, Basu A, Gardner RM, Aspelund S, Wen X, Yanovski JA.
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| Biochem Biophys Res Commun 454(1):234-8. doi: 10.1016/j.bbrc.2014.10.072. Epub 2014 Oct 22.
2014
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7 | MC3R
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| Functions of the DRY motif and intracellular loop 2 of human melanocortin 3 receptor.
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| Huang H, Tao YX.
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| J Mol Endocrinol 53(3):319-30. doi: 10.1530/JME-14-0184. Epub 2014 Sep 16.
2014
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8 | MC3R
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| Association analysis of melanocortin 3 receptor polymorphisms with the risk of pulmonary tuberculosis.
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| Park BL, Kim LH, Namgoong S, Kim JO, Kim JY, Chang HS, Park JS, Jang AS, Park SW, Kim DJ, Kim KU, Kim YG, Uh ST, Seo KH, Kim YH, Park CS, Shin HD.
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| Lung 192(6):857-62. doi: 10.1007/s00408-014-9625-2. Epub 2014 Jul 27.
2014
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9 | MC3R
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| Functions of the third intracellular loop of the human melanocortin-3 receptor.
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| Wang ZQ, Tao YX.
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| Curr Pharm Des 19(27):4831-8.
2013
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10 | MC3R
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| Melanocortin 3/4 receptors in paraventricular nucleus modulate sympathetic outflow and blood pressure.
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| Li P, Cui BP, Zhang LL, Sun HJ, Liu TY, Zhu GQ.
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| Exp Physiol 98(2):435-43. doi: 10.1113/expphysiol.2012.067256. Epub 2012 Aug 7.
2013
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11 | MC3R
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| Functional characterization of nine novel naturally occurring human melanocortin-3 receptor mutations.
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| Yang F, Tao YX.
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| Biochim Biophys Acta 1822(11):1752-61. doi: 10.1016/j.bbadis.2012.07.017. Epub 2012 Aug 3.
2012
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12 | MC3R
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| Melanocortin-3 receptor regulates the normal fasting response.
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| Renquist BJ, Murphy JG, Larson EA, Olsen D, Klein RF, Ellacott KL, Cone RD.
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| Proc Natl Acad Sci U S A 109(23):E1489-98. doi: 10.1073/pnas.1201994109. Epub 2012 May 9.
2012
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13 | CTSZ, MC3R
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| Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility.
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| Adams LA, Möller M, Nebel A, Schreiber S, van der Merwe L, van Helden PD, Hoal EG.
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| Eur J Hum Genet 19(6):676-81. Epub 2011 Feb 2.
2011
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14 | MC3R
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| Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis.
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| Begriche K, Levasseur PR, Zhang J, Rossi J, Skorupa D, Solt LA, Young B, Burris TP, Marks DL, Mynatt RL, Butler AA.
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| J Biol Chem 286(47):40771-81. Epub 2011 Oct 7.
2011
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15 | MC3R
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| Implication of the melanocortin-3 receptor in the regulation of food intake.
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| Irani BG, Xiang Z, Yarandi HN, Holder JR, Moore MC, Bauzo RM, Proneth B, Shaw AM, Millard WJ, Chambers JB, Benoit SC, Clegg DJ, Haskell-Luevano C.
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| Eur J Pharmacol 660(1):80-7. Epub 2011 Jan 1.
2011
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16 | MC3R
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| Mutations in the melanocortin-3 receptor (MC3R) gene: Impact on human obesity or adiposity.
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| Tao YX.
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| Curr Opin Investig Drugs 11(10):1092-6. Review.
2010
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17 | MC3R
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| Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle.
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| Sutton GM, Begriche K, Kumar KG, Gimble JM, Perez-Tilve D, Nogueiras R, McMillan RP, Hulver MW, Tschöp MH, Butler AA.
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| FASEB J 24(3):862-72. Epub 2009 Oct 16.
2010
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18 | MC3R
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| Sporadic mutations in melanocortin receptor 3 in morbid obese individuals.
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| Mencarelli M, Walker GE, Maestrini S, Alberti L, Verti B, Brunani A, Petroni ML, Tagliaferri M, Liuzzi A, Di Blasio AM.
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| Eur J Hum Genet 16(5):581-6. Epub 2008 Jan 30. 2008
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19 | MC3R
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| The melanocortin-3 receptor is required for entrainment to meal intake.
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| Sutton GM, Perez-Tilve D, Nogueiras R, Fang J, Kim JK, Cone RD, Gimble JM, Tschöp MH, Butler AA.
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| J Neurosci 28(48):12946-55.
2008
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20 | MC3R
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| Functions of acidic transmembrane residues in human melanocortin-3 receptor binding and activation.
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| Wang SX, Fan ZC, Tao YX.
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| Biochem Pharmacol 76(4):520-30. Epub 2008 Jul 9.
2008
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21 | CTSZ, MC3R
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| Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis.
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| Cooke GS, Campbell SJ, Bennett S, Lienhardt C, McAdam KP, Sirugo G, Sow O, Gustafson P, Mwangulu F, van Helden P, Fine P, Hoal EG, Hill AV.
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| Am J Respir Crit Care Med 178(2):203-7. Epub 2008 Apr 17. Erratum in: Am J Respir Crit Care Med. 2009 Apr 1;179(7):624.
2008
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22 | MC3R
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| Activation and endocytic internalization of melanocortin 3 receptor in neuronal cells.
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| Wachira SJ, Guruswamy B, Uradu L, Hughes-Darden CA, Denaro FJ.
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| Ann N Y Acad Sci 1096:271-86.
2007
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23 | MC3R
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| Molecular characterization of human melanocortin-3 receptor ligand-receptor interaction.
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| Chen M, Aprahamian CJ, Celik A, Georgeson KE, Garvey WT, Harmon CM, Yang Y.
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| Biochemistry 45(4):1128-37. 2006
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24 | MC3R
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| Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation.
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| Tao YX, Segaloff DL.
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| J Clin Endocrinol Metab 89(8):3936-42.
2004
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25 | MC3R
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| A novel melanocortin 3 receptor gene (MC3R) mutation associated with severe obesity.
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| Lee YS, Poh LK, Loke KY.
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| J Clin Endocrinol Metab 87(3):1423-6. 2002
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26 | MC1R, HADC, MC3R, MC4R
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| Deletions of the N-terminal regions of the human melanocortin receptors.
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| Schioth HB, Petersson S, Muceniece R, Szardenings M, Wikberg JE.
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| FEBS Lett 410(2-3):223-8. 1997
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27 | MC1R, HADC, MC3R, MC4R, MC1RH1, MC1RH2
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| Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in the mouse and human.
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| Magenis RE, et al.
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| Mamm Genome 5 : 503-508. 1994
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28 | MC1R, MC3R, MC4R
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| Molecular cloning of a novel melanocortin receptor.
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| Gantz I, et al.
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| J Biol Chem 268 : 8246-8250. 1993
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29 | MC4R, HADC, MC3R
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| Molecular cloning, expression, and gene localization of a fourth melanocortin receptor.
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| Gantz I, et al.
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| J Biol Chem 268 : 15174-15179. 1993
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30 | MC4R, HADC, MC3R
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| Localization of the genes encoding the melanocortin-2 (adrenocorticotropic hormone) and melanocortin-3 receptors to chromosomes 18p11.2 and 20q13.2-q13.3 by fluorescence in situ hybridization.
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| Gantz I, et al.
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| Genomics 18 : 166-167. 1993
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