Citations for
1MBD2
Genome-Wide Binding of MBD2 Reveals Strong Preference for Highly Methylated Loci.
Menafra R, Brinkman AB, Matarese F, Franci G, Bartels SJ, Nguyen L, Shimbo T, Wade PA, Hubner NC, Stunnenberg HG.
PLoS One 9(6):e99603. doi: 10.1371/journal.pone.0099603. eCollection 2014. 2014
2MBD2
Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells.
Lu Y, Loh YH, Li H, Cesana M, Ficarro SB, Parikh JR, Salomonis N, Toh CX, Andreadis ST, Luckey CJ, Collins JJ, Daley GQ, Marto JA.
Cell Stem Cell ell Stem Cell. 2014 May 7. pii: S1934-5909(14)00139-8. doi: 10.1016/j.stem.2014.04.002. [Epub ahead of print] 2014
3GATAD2A, MBD2, MBD3
Unique features of the anti-parallel, heterodimeric coiled-coil interaction between methyl-cytosine binding domain 2 (MBD2) homologues and GATA zinc finger domain containing 2A (GATAD2A/p66α).
Walavalkar NM, Gordon N, Williams DC Jr.
J Biol Chem 288(5):3419-27. doi: 10.1074/jbc.M112.431346. Epub 2012 Dec 13. 2013
4FOXP3, MBD2
Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.
Wang L, Liu Y, Han R, Beier UH, Thomas RM, Wells AD, Hancock WW.
Mol Cell Biol 33(20):4106-15. doi: 10.1128/MCB.00144-13. Epub 2013 Aug 26. 2013
5CEBPA, MBD2
Transcription onset of genes critical in liver carcinogenesis is epigenetically regulated by methylated DNA-binding protein MBD2.
Stefanska B, Suderman M, Machnes Z, Bhattacharyya B, Hallett M, Szyf M.
Carcinogenesis 34(12):2738-49. doi: 10.1093/carcin/bgt273. Epub 2013 Aug 16. 2013
6MBD2, MBD3
Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences.
Günther K, Rust M, Leers J, Boettger T, Scharfe M, Jarek M, Bartkuhn M, Renkawitz R.
Nucleic Acids Res 41(5):3010-21. doi: 10.1093/nar/gkt035. Epub 2013 Jan 29. 2013
7MBD2, MECP2
Direct homo- and hetero-interactions of MeCP2 and MBD2.
Becker A, Allmann L, Hofstätter M, Casà V, Weber P, Lehmkuhl A, Herce HD, Cardoso MC.
PLoS One 8(1):e53730. doi: 10.1371/journal.pone.0053730. Epub 2013 Jan 15. 2013
8CHD4, MBD2
MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes.
Ramírez J, Dege C, Kutateladze TG, Hagman J.
Mol Cell Biol 32(24):5078-88. doi: 10.1128/MCB.00819-12. Epub 2012 Oct 15. 2012
9MBD2, MBD4
Decreased expression of MBD2 and MBD4 gene and genomic-wide hypomethylation in patients with primary immune thrombocytopenia.
Chen ZP, Gu DS, Zhou ZP, Chen XL, Guo ZX, Du WT, Ge J, Ren Q, Yang RC.
Hum Immunol 72(6):486-91. Epub 2011 Mar 3. 2011
10MBD2
Preferential binding of the methyl-CpG binding domain protein 2 at methylated transcriptional start site regions.
Chatagnon A, Perriaud L, Nazaret N, Croze S, Benhattar J, Lachuer J, Dante R.
Epigenetics 6(11):1295-307. doi: 10.4161/epi.6.11.17875. Epub 2011 Nov 1. 2011
11MBD2
Methyl-binding domain protein 2-dependent proliferation and survival of breast cancer cells.
Mian OY, Wang SZ, Zhu SZ, Gnanapragasam MN, Graham L, Bear HD, Ginder GD.
Mol Cancer Res 9(8):1152-62. doi: 10.1158/1541-7786.MCR-11-0252. Epub 2011 Jun 21. 2011
12MBD2
MBD2 contributes to developmental silencing of the human ε-globin gene.
Rupon JW, Wang SZ, Gnanapragasam M, Labropoulos S, Ginder GD.
Blood Cells Mol Dis 46(3):212-9. doi: 10.1016/j.bcmd.2011.01.001. Epub 2011 Feb 4. 2011
13MBD2, MECP2
MBD2 and MeCP2 regulate distinct transitions in the stage-specific differentiation of olfactory receptor neurons.
Macdonald JL, Verster A, Berndt A, Roskams AJ.
Mol Cell Neurosci 44(1):55-67. doi: 10.1016/j.mcn.2010.02.003. Epub 2010 Feb 24. 2010
14MBD2, TERT
Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells.
Chatagnon A, Bougel S, Perriaud L, Lachuer J, Benhattar J, Dante R.
Carcinogenesis 30(1):28-34. Epub 2008 Oct 24. 2009
15BRDT, EZH2, MBD1, MBD2, MBD3L1, PWRN1, PWRN2, SUV39H2
Expression of SNURF-SNRPN upstream transcripts and epigenetic regulatory genes during human spermatogenesis.
Wawrzik M, Spiess AN, Herrmann R, Buiting K, Horsthemke B.
Eur J Hum Genet 17(11):1463-70. Epub 2009 May 27.PMID: 19471314 2009
16MAGEA1, MAGEA12, MAGEA2, MAGEA3, MBD1, MBD2, MECP2
Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters.
Wischnewski F, Friese O, Pantel K, Schwarzenbach H.
Mol Cancer Res 5(7):749-59. 2007
17MBD2
MBD2 is required for correct spatial gene expression in the gut.
Berger J, Sansom O, Clarke A, Bird A.
Mol Cell Biol 27(11):4049-57. Epub 2007 Mar 12. 2007
18MBD2, MBD4
Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients.
Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Vilardell-Tarrés M.
J Leukoc Biol 81(6):1609-16. Epub 2007 Mar 14. 2007
19RET, MBD2, MBD4
RET finger protein enhances MBD2- and MBD4-dependent transcriptional repression.
Fukushige S, Kondo E, Gu Z, Suzuki H, Horii A.
Biochem Biophys Res Commun 351(1):85-92. Epub 2006 Oct 10. 2006
20MBD2, MBD3, PRMT5, WDR77
MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.
Le Guezennec X, Vermeulen M, Brinkman AB, Hoeijmakers WA, Cohen A, Lasonder E, Stunnenberg HG.
Mol Cell Biol 26(3):843-51. 2006
21MBD2
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression.
Ghoshal K, Majumder S, Datta J, Motiwala T, Bai S, Sharma SM, Frankel W, Jacob ST.
J Biol Chem 279(8):6783-93. Epub 2003 Nov 10. 2004
22MBD3L1, MBD2, MBD3
MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.
Jiang CL, Jin SG, Pfeifer GP.
J Biol Chem 279(50):52456-64. Epub 2004 Sep 28. 2004
23ATRX, DNMT1, DNMT3B, HDAC1, HDAC2, KAT2B, KAT8, MBD1, MBD2, MECP2, SIN3A
Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.
Craig JM, Earle E, Canham P, Wong LH, Anderson M, Choo KH.
Hum Mol Genet 12(23):3109-21. Epub 2003 Sep 30. 2003
24MBD1, MBD2, CXXC1
MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers.
Bader S, Walker M, McQueen HA, Sellar R, Oei E, Wopereis S, Zhu Y, Peter A, Bird AP, Harrison DJ.
Oncogene 22(22):3506-10. 2003
25MBD2
Promoter-specific activation and demethylation by MBD2/demethylase.
Detich N, Theberge J, Szyf M.
J Biol Chem 277(39):35791-4. Epub 2002 Aug 12. 2002
26GATAD2A, GATAD2B, MBD3, MBD2
Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3.
Brackertz M, Boeke J, Zhang R, Renkawitz R.
J Biol Chem 277(43):40958-66. Epub 2002 Aug 14. 2002
27MBD2
A mammalian protein with specific demethylase activity for mCpG DNA.
Bhattacharya SK, et al.
Nature 397 : 579-583. 1999
28MBD2
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.
Ng HH, et al.
Nat Genet 23(1):58-61 1999
29MBD2, MBD4
Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes.
Hendrich B, Abbott C, McQueen H, Chambers D, Cross S, Bird A.
Mamm Genome 10(9):906-12 1999
30MBD2
Reduced mRNA expression of the DNA demethylase, MBD2, in human colorectal and stomach cancers.
Kanai Y, Ushijima S, Nakanishi Y, Hirohashi S.
Biochem Biophys Res Commun 264(3):962-6 1999
31MBD2
A mammalian protein with specific demethylase activity for mCpG DNA.
Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M.
Nature 397(6720):579-83. 1999
32MBD1, MBD2, MBD3, MBD4
Identification and characterization of a family of mammalian methyl-CpG binding proteins.
Hendrich B, et al.
Mol Cell Biol 18 : 6538-6547. 1998
33CWC27, HSPH1, MBD2, SDCCAG1, SDCCAG3, SDCCAG8, STARD10, STUB1, TSHZ1, USH1C, UTP14A, WNK2
Characterization of human colon cancer antigens recognized by autologous antibodies.
Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, TureciO, Sahin U, Pfreundschuh M, Old LJ.
Int J Cancer 76(5):652-8. 1998