1 | CGAS, MARCHF8
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| MARCH8 attenuates cGAS-mediated innate immune responses through ubiquitylation
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| Yang X, Shi C, Li H, Shen S, Su C, Yin H.
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| Sci Signal. May 3;15(732):eabk3067. doi: 10.1126/scisignal.abk3067. Epub 2022 May 3. 2022
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2 | MARCHF1, MARCHF8
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| Physiological substrates and ontogeny-specific expression of the ubiquitin ligases MARCH1 and MARCH8
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| Schriek P, Liu H, Ching AC, Huang P, Gupta N, Wilson KR, Tsai M, Yan Y, Macri CF, Dagley LF, Infusini G, Webb AI, McWilliam HEG, Ishido S, Mintern JD, Villadangos JA.
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| Curr Res Immunol. Oct 15;2:218-228. doi: 10.1016/j.crimmu.2021.10.004 2021
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3 | MARCHF8
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| MARCH8 inhibits viral infection by two different mechanisms
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| Zhang Y, Tada T, Ozono S, Kishigami S, Fujita H, Tokunaga K.
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| Elife. Aug 11;9:e57763. doi: 10.7554/eLife.57763. 2020
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4 | BST2, MARCHF8, NEDD4
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| Characterization of E3 ligases involved in lysosomal sorting of the HIV-1 restriction factor BST2.
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| Roy N, Pacini G, Berlioz-Torrent C, Janvier K.
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| J Cell Sci 130(9):1596-1611. doi: 10.1242/jcs.195412. Epub 2017 Mar 20. 2017
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5 | MARCHF8
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| MARCH8 is associated with poor prognosis in non-small cell lung cancers patients.
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| Fan J, Tian L, Li M, Huang SH, Zhang J, Zhao B.
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| Oncotarget Nov 21;8(64):108238-108248. doi: 10.18632/oncotarget.22602. 2017
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6 | CD83, MARCHF8
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| Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection
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| Liu H, Jain R, Guan J, Vuong V, Ishido S, La Gruta NL, Gray DH, Villadangos JA, Mintern JD.
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| J Exp Med. Aug 22;213(9):1695-703. doi: 10.1084/jem.20160312. Epub 2016 Aug 8. 2016
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7 | MARCHF1, MARCHF8, SLC2A3
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| Ubiquitylation of CD98 limits cell proliferation and clonal expansion
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| Ablack JN, Metz PJ, Chang JT, Cantor JM, Ginsberg MH.
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| J Cell Sci. Dec 1;128(23):4273-8. doi: 10.1242/jcs.178129. Epub 2015 Oct 22. 2015
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8 | MARCHF1, MARCHF8, TNFRSF10A
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| Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1
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| van de Kooij B, Verbrugge I, de Vries E, Gijsen M, Montserrat V, Maas C, Neefjes J, Borst J.
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| J Biol Chem. Mar 1;288(9):6617-28. doi: 10.1074/jbc.M112.448209. Epub 2013 Jan 8. 2013
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9 | IL1RAP, MARCHF8
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| The E3 ubiquitin ligase MARCH8 negatively regulates IL-1β-induced NF-κB activation by targeting the IL1RAP coreceptor for ubiquitination and degradation.
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| Chen R, Li M, Zhang Y, Zhou Q, Shu HB.
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| Proc Natl Acad Sci U S A 109(35):14128-33. doi: 10.1073/pnas.1205246109. Epub 2012 Aug 16. 2012
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10 | MARCHF4, MARCHF8
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| Structural requirements for recognition of major histocompatibility complex class II by membrane-associated RING-CH (MARCH) protein E3 ligases.
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| Jahnke M, Trowsdale J, Kelly AP.
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| J Biol Chem 287(34):28779-89. doi: 10.1074/jbc.M112.381541. Epub 2012 Jul 3. 2012
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11 | MARCHF8, MARCHF9
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| Structural requirements for recognition of major histocompatibility complex class II by membrane-associated RING-CH (MARCH) protein E3 ligases.
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| Jahnke M, Trowsdale J, Kelly AP.
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| J Biol Chem 287(34):28779-89. doi: 10.1074/jbc.M112.381541. Epub 2012 Jul 3. 2012
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12 | MARCHF8, SLC3A2
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| MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.
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| Eyster CA, Cole NB, Petersen S, Viswanathan K, Früh K, Donaldson JG.
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| Mol Biol Cell 22(17):3218-30. Epub 2011 Jul 14. 2011
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13 | BCAP31, CD44, CD81, MARCHF4, MARCHF8
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| Membrane-Associated RING-CH proteins associate with Bap31 and target CD81 and CD44 to lysosomes.
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| Bartee E, Eyster CA, Viswanathan K, Mansouri M, Donaldson JG, Früh K.
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| PLoS One 5(12):e15132. 2010
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14 | CD4, HLA-A, MARCHF1, MARCHF2, MARCHF3, MARCHF4, MARCHF5, MARCHF6, MARCHF7, MARCHF8, MARCHF9, UBB, UBE2H
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| Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.
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| Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Fruh K.
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| J Virol 78(3):1109-20. 2004
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15 | MARCHF8
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| c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity.
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| Goto E, Ishido S, Sato Y, Ohgimoto S, Ohgimoto K, Nagano-Fujii M, Hotta H.
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| J Biol Chem 278(17):14657-68. Epub 2003 Feb 11. 2003
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16 | MARCHF8, MYLIP
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| Neuronal expression of the ERM-like protein MIR in rat brain and its localization to human chromosome 6.
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| Olsson PA, Bornhauser BC, Korhonen L, Lindholm D.
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| Biochem Biophys Res Commun 279(3):879-83. 2000
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