Citations for
1MAP2K7, MAPK8, SENP3
DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
Lao Y, Yang K, Wang Z, Sun X, Zou Q, Yu X, Cheng J, Tong X, Yeh ETH, Yang J, Yi J.
J Biol Chem 293(11):3965-3980. doi: 10.1074/jbc.M117.816769. Epub 2018 Jan 19. 2018
2MAP2K7, MAPK8
Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.
Yamasaki T, Deki-Arima N, Kaneko A, Miyamura N, Iwatsuki M, Matsuoka M, Fujimori-Tonou N, Okamoto-Uchida Y, Hirayama J, Marth JD, Yamanashi Y, Kawasaki H, Yamanaka K, Penninger JM, Shibata S, Nishina H.
Sci Rep 7(1):7348. doi: 10.1038/s41598-017-07845-x. 2017
3MAPK8, TRAF5
Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis.
Gao L, Wang PX, Zhang Y, Yu CJ, Ji Y, Wang X, Zhang P, Jiang X, Jin H, Huang Z, Zhang ZR, Li H.
J Hepatol 65(1):125-136. doi: 10.1016/j.jhep.2016.03.006. Epub 2016 Mar 23. 2016
4AURKA, MAPK8, MAPK9, WDR62
Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules.
Lim NR, Yeap YY, Zhao TT, Yip YY, Wong SC, Xu D, Ang CS, Williamson NA, Xu Z, Bogoyevitch MA, Ng DC.
J Cell Sci 128(3):527-40. 2015
5MAP2K4, MAPK8, TGFB1I1
Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms.
Lei XF, Kim-Kaneyama JR, Arita-Okubo S, Offermanns S, Itabe H, Miyazaki T, Miyazaki A.
J Am Heart Assoc 3(3):e000747. doi: 10.1161/JAHA.113.000747. 2014
6MAPK8, SH3BP5
JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death.
Win S, Than TA, Fernandez-Checa JC, Kaplowitz N.
Cell Death Dis 5:e989. doi: 10.1038/cddis.2013.522. 2014
7MAPK8, MUC1
MUC1 activates JNK1 and inhibits apoptosis under genotoxic stress.
Chen Q, Li D, Ren J, Li C, Xiao ZX.
Biochem Biophys Res Commun 440(1):179-83. doi: 10.1016/j.bbrc.2013.09.055. Epub 2013 Sep 18. 2013
8DCC, DSCAM, MAPK8, NTN1, UNC5C
c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance.
Qu C, Li W, Shao Q, Dwyer T, Huang H, Yang T, Liu G.
J Biol Chem 288(3):1883-95. doi: 10.1074/jbc.M112.417881. Epub 2012 Dec 6. 2013
9AJUBA, MAPK8
Ajuba family proteins link JNK to Hippo signaling.
Sun G, Irvine KD.
Sci Signal 6(292):ra81. doi: 10.1126/scisignal.2004324. 2013
10IRS2, MAPK8, MAPK9, MAPK9
JNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: functional consequences for insulin signaling.
Abdelli S, Bonny C.
PLoS One 7(5):e35997. doi: 10.1371/journal.pone.0035997. Epub 2012 May 1. 2012
11LPIN2, MAPK8
Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages.
Valdearcos M, Esquinas E, Meana C, Peńa L, Gil-de-Gómez L, Balsinde J, Balboa MA.
J Biol Chem 287(14):10894-904. doi: 10.1074/jbc.M112.342915. Epub 2012 Feb 8. 2012
12MAP2K7, MAPK8, TNFRSF18
Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation.
Joetham A, Ohnishi H, Okamoto M, Takeda K, Schedel M, Domenico J, Dakhama A, Gelfand EW.
J Biol Chem 287(21):17100-8. doi: 10.1074/jbc.M111.316943. Epub 2012 Mar 29. 2012
13CTGF, MAPK8
Activation of JNK signaling mediates connective tissue growth factor expression and scar formation in corneal wound healing.
Shi L, Chang Y, Yang Y, Zhang Y, Yu FS, Wu X.
PLoS One 7(2):e32128. doi: 10.1371/journal.pone.0032128. Epub 2012 Feb 21. 2012
14MAPK8, PXN
Paxillin is the target of c-Jun N-terminal kinase in Schwann cells and regulates migration.
Miyamoto Y, Torii T, Yamamori N, Eguchi T, Nagao M, Nakamura K, Tanoue A, Yamauchi J.
Cell Signal 24(11):2061-9. doi: 10.1016/j.cellsig.2012.06.013. Epub 2012 Jun 30. 2012
15MAPK8, RAD18
c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks.
Barkley LR, Palle K, Durando M, Day TA, Gurkar A, Kakusho N, Li J, Masai H, Vaziri C.
Mol Biol Cell 23(10):1943-54. doi: 10.1091/mbc.E11-10-0829. Epub 2012 Mar 28. 2012
16ADARB1, MAPK8
c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells.
Yang L, Huang P, Li F, Zhao L, Zhang Y, Li S, Gan Z, Lin A, Li W, Liu Y.
PLoS One 7(11):e48611. doi: 10.1371/journal.pone.0048611. Epub 2012 Nov 6. 2012
17MAPK1, MAPK3, MAPK8
Differential roles of ERK1/2 and JNK in retinal development and degeneration.
Donovan M, Doonan F, Cotter TG.
J Neurochem. 116(1):33-42. 2011
18MAPK8, MAPK9
Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation.
Cellurale C, Sabio G, Kennedy NJ, Das M, Barlow M, Sandy P, Jacks T, Davis RJ.
Mol Cell Biol 31(7):1565-76. Epub 2011 Jan 31. 2011
19MAPK8, SIRT1
Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity.
Gao Z, Zhang J, Kheterpal I, Kennedy N, Davis RJ, Ye J.
J Biol Chem 286(25):22227-34. Epub 2011 May 3. 2011
20GNA12, MAPK8, ROCK1
G12 signaling through c-Jun NH2-terminal kinase promotes breast cancer cell invasion.
Juneja J, Cushman I, Casey PJ.
PLoS One 6(11):e26085. doi: 10.1371/journal.pone.0026085. Epub 2011 Nov 7. 2011
21MAPK8
Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1.
Sabio G, Cavanagh-Kyros J, Barrett T, Jung DY, Ko HJ, Ong H, Morel C, Mora A, Reilly J, Kim JK, Davis RJ.
Genes Dev 24(3):256-64. Epub 2010 Jan 15. 2010
22MAPK8
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism.
Belgardt BF, Mauer J, Wunderlich FT, Ernst MB, Pal M, Spohn G, Brönneke HS, Brodesser S, Hampel B, Schauss AC, Brüning JC.
Proc Natl Acad Sci U S A 107(13):6028-33. Epub 2010 Mar 15. 2010
23MAPK8, MAPK9
JNK1 and JNK2 differently regulate IL-12 production in THP-1 macrophage cells.
Utsugi M, Dobashi K, Ono A, Ishizuka T, Hisada T, Koga Y, Shimizu Y, Kawata T, Matsuzaki S, Aoki H, Kamide Y, Mori M.
Cytokine 51(2):127-31. Epub 2010 May 18. 2010
24BRSK1, BRSK2, CDC42, DCX, DOCK7, DPYSL2, GSK3A, GSK3B, IGF1, KIF13B, KIF2A, KLC1, LIS1, MAP1B, MAP2, MAPK8, MAPT, NIN, PAFAH1B1, SCG10, SCLIP, STK11, STMN1, STMN2, STMN3, STRADA
Microtubule assembly, organization and dynamics in axons and dendrites.
Conde C, Caceres A.
Nat Rev Neurosci. 10(5):319-32. 2009
25MAPK8, SIRT1
JNK1 phosphorylates SIRT1 and promotes its enzymatic activity.
Nasrin N, Kaushik VK, Fortier E, Wall D, Pearson KJ, de Cabo R, Bordone L.
PLoS One. 4(12):e8414. 2009
26MAPK8, MAPK9
Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.
Gancz D, Donin N, Fishelson Z.
Mol Immunol 47(2-3):310-7. Epub 2009 Oct 27. 2009
27MAPK8
A stress signaling pathway in adipose tissue regulates hepatic insulin resistance.
Sabio, G.; Das, M.; Mora, A.; Zhang, Z.; Jun, J. Y.; Ko, H. J.; Barrett, T.; Kim, J. K.; Davis, R. J.
Science. 322: 1539-1543 2008
28MAPK8, MPRIP
M-RIP, a novel target of JNK signaling and a requirement for human cancer cell invasion.
Ono R, Matsuoka J, Yamatsuji T, Naomoto Y, Tanaka N, Matsui H, Matsushita M.
Int J Mol Med 22(2):199-203. 2008
29IFIT3, IFNA1, MAPK8, PRKCD
Sequential activation of protein kinase C delta and JNK is required for interferon-alpha-induced expression of IFIT4.
Huang X, Yang N, Ou X, Li D, Wang Z, Xie Q, Chen Y, Lin H, Yin G, Wen F.
Cell Signal 20(1):112-9. 2008
30ALDH1L1, MAPK8, MAPK9
Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway.
Oleinik NV, Krupenko NI, Krupenko SA.
Oncogene 26(51):7222-30. Epub 2007 May 21.PMID: 17525747 2007
31MAPK8
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.
Tuncman, G.; Hirosumi, J.; Solinas, G.; Chang, L.; Karin, M.; Hotamisligil, G. S.
Proc. Nat. Acad. Sci. 103: 10741-10746 2006
32MAPK8
Inactivation of JNK1 enhances innate IL-10 production and dampens autoimmune inflammation in the brain.
Tran, E. H.; Azuma, Y.-T.; Chen, M.; Weston, C.; Davis, R. J.; Flavell, R. A.
Proc. Nat. Acad. Sci. 103: 13451-13456 2006
33JUN, MAPK8
Neuroprotection by histone deacetylase-related protein.
Morrison BE, Majdzadeh N, Zhang X, Lyles A, Bassel-Duby R, Olson EN, D'Mello SR.
Mol Cell Biol. 26(9):3550-64. 2006
34RP1, MAPK8, MAPK9, MAPK10, MAP2K4 , MAP2, JUN
Distinct gene expression profiles and reduced JNK signaling in retinitis pigmentosa caused by RP1 mutations.
Liu J, Huang Q, Higdon J, Liu W, Xie T, Yamashita T, Cheon K, Cheng C, Zuo J.
Hum Mol Genet 14(19):2945-58. Epub 2005 Aug 26. 2005
35ARHGAP1, MAPK8
Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion and engraftment.
Wang L, Yang L, Filippi MD, Williams DA, Zheng Y.
Blood [Epub ahead of print] 2005
36MAPK8
Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase.
Yoshimura K, Aoki H, Ikeda Y, Fujii K, Akiyama N, Furutani A, Hoshii Y, Tanaka N, Ricci R, Ishihara T, Esato K, Hamano K, Matsuzaki M.
Nat Med 11(12):1330-8. Epub 2005 Nov 27. 2005
37MAP4K4, MAPK8, MMP9, SPP1
JNK1 differentially regulates osteopontin-induced nuclear factor-inducing kinase/MEKK1-dependent activating protein-1-mediated promatrix metalloproteinase-9 activation.
Rangaswami H, Bulbule A, Kundu GC.
J Biol Chem 280(19):19381-92. Epub 2005 Mar 9. 2005
38JKAMP, MAPK8
JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity.
Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, Asahara T, Bhoumik A, Ronai Z.
Mol Cell Biol 25(19):8619-30. 2005
39MAP3K7, MAPK8, XIAP
X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1).
Kaur S, Wang F, Venkatraman M, Arsura M.
J Biol Chem 280(46):38599-608. Epub 2005 Sep 12. 2005
40DUSP1, MAPK8
DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.
Hamdi M, Kool J, Cornelissen-Steijger P, Carlotti F, Popeijus HE, van der Burgt C, Janssen JM, Yasui A, Hoeben RC, Terleth C, Mullenders LH, van Dam H.
Oncogene 24(48):7135-44. 2005
41MAPK8
The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity.
Choi BY, Choi HS, Ko K, Cho YY, Zhu F, Kang BS, Ermakova SP, Ma WY, Bode AM, Dong Z.
Nat Struct Mol Biol. 12(8):699-707. 2005
42MAPK8, XBP1, IRS1
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS.
Science 306(5695):457-61. 2004
43MAPK8, MAPK9
The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis.
Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ.
Proc Natl Acad Sci U S A 101(39):14114-9. Epub 2004 Sep 16. 2004
44CYLD, IKBKB, IKBKG, MAPK8, MAP2K7
Negative regulation of JNK signaling by the tumor suppressor CYLD.
Reiley W, Zhang M, Sun SC.
J Biol Chem 279(53):55161-7. Epub 2004 Oct 20. 2004
45MAPK8
Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide.
Kaneto, H.; Nakatani, Y.; Miyatsuka, T.; Kawamori, D.; Matsuoka, T.; Matsuhisa, M.; Kajimoto, Y.; Ichijo, H.; Yamasaki, Y.; Hori, M.
Nat Med. 10: 1128-1132 2004
46MAPK8
JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD.
Yu C, Minemoto Y, Zhang J, Liu J, Tang F, Bui TN, Xiang J, Lin A.
Mol Cell. 13(3):329-40. 2004
47BID, CASP8, DIABLO, MAPK8, TNF
A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
Deng Y, Ren X, Yang L, Lin Y, Wu X.
Cell 115(1):61-70. 2003
48MAPK8
JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins.
Chang L, Jones Y, Ellisman MH, Goldstein LS, Karin M.
Dev Cell. 4(4):521-33. 2003
49MAPK8
A central role for JNK in obesity and insulin resistance.
Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS.
Nature 420(6913):333-6. 2002
50CREB1, MAPK8, SKI, JUN, SMAD2
c-Jun associates with the oncoprotein Ski and suppresses Smad2 transcriptional activity.
Pessah M, Marais J, Prunier C, Ferrand N, Lallemand F, Mauviel A, Atfi A.
J Biol Chem 277(32):29094-100. 2002
51MAPK8, SH3BP5
A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria.
Wiltshire C, Matsushita M, Tsukada S, Gillespie DA, May GH.
Biochem J 367(Pt 3):577-85. 2002
52MAP3K7, MAPK8
IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.
Sanna MG, da Silva Correia J, Ducrey O, Lee J, Nomoto K, Schrantz N, Deveraux QL, Ulevitch RJ.
Mol Cell Biol. 22(6):1754-66. 2002
53MAPK8
Gamma-synuclein promotes cancer cell survival and inhibits stress- and chemotherapy drug-induced apoptosis by modulating MAPK pathways.
Pan ZZ, Bruening W, Giasson BI, Lee VM, Godwin AK.
J Biol Chem. 277(38):35050-60 2002
54JUN, MAPK8
Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus.
Hurd C, Waldron RT, Rozengurt E.
Oncogene. 21(14):2154-60 2002
55MAPK8
Survival signaling mediated by c-Jun NH2-terminal kinase in transformed B lymphoblasts.
Hess, P.; Pihan, G.; Sawyers, C. L.; Flavell, R. A.; Davis, R. J.
Nature Genet. 32: 201-205 2002
56MAPK8
The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway.
Chen AJ, Zhou G, Juan T, Colicos SM, Cannon JP, Cabriera-Hansen M, Meyer CF, Jurecic R, Copeland NG, Gilbert DJ, Jenkins NA, Fletcher F, Tan TH, Belmont JW.
J Biol Chem. 277(39):36592-601. 2002
57ELP1, MAPK8
A novel specific role for I kappa B kinase complex-associated protein in cytosolic stress signaling.
Holmberg C, Katz S, Lerdrup M, Herdegen T, Jäättelä M, Aronheim A, Kallunki T.
J Biol Chem. 277(35):31918-28. 2002
58MAPK8
A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation.
Girardin SE, Yaniv M.
EMBO J. 20(13):3437-46. 2001
59GSTP1, MAPK8
Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus.
Wang T, Arifoglu P, Ronai Z, Tew KD.
J Biol Chem. 276(24):20999-1003 2001
60MAPK1, MAPK3, MAPK8
Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1.
Slack DN, Seternes OM, Gabrielsen M, Keyse SM.
J Biol Chem. 276(19):16491-500. 2001
61MAP2K7, MAPK8, MAPK8IP1, MAPK8IP2
cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein.
Negri S, Oberson A, Steinmann M, Sauser C, Nicod P, Waeber G, Schorderet DF, Bonny C.
Genomics 64(3):324-30. 2000
62MAPK8
JNK is required for effector T-cell function but not for T-cell activation.
Dong C, Yang DD, Tournier C, Whitmarsh AJ, Xu J, Davis RJ, Flavell RA.
Nature 405(6782):91-4. 2000
63MAPK8
c-Jun NH2-terminal kinase targeting and phosphorylation of heat shock factor-1 suppress its transcriptional activity.
Dai R, Frejtag W, He B, Zhang Y, Mivechi NF.
J Biol Chem. 275(24):18210-8. 2000
64MAPK8
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307).
Aguirre V, Uchida T, Yenush L, Davis R, White MF.
J Biol Chem. 275(12):9047-54. 2000
65MAPK8
Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation.
Cheng J, Yang J, Xia Y, Karin M, Su B.
Mol Cell Biol. 20(7):2334-42. 2000
66COPS2, MAPK8
COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK.
Naumann M, Bech-Otschir D, Huang X, Ferrell K, Dubiel W.
J Biol Chem 274(50):35297-300. 1999
67MAPK8
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription.
Engel ME, McDonnell MA, Law BK, Moses HL.
J Biol Chem. 274(52):37413-20. 1999
68DUSP10, MAPK8
Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5.
Tanoue T, Moriguchi T, Nishida E.
J Biol Chem. 274(28):19949-56. 1999
69MAPK8
Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase.
Noguchi K, Kitanaka C, Yamana H, Kokubu A, Mochizuki T, Kuchino Y.
J Biol Chem. 274(46):32580-7. 1999
70MAPK8
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway.
Ito M, Yoshioka K, Akechi M, Yamashita S, Takamatsu N, Sugiyama K, Hibi M, Nakabeppu Y, Shiba T, Yamamoto KI.
Mol Cell Biol. 19(11):7539-48. 1999
71MAPK8, MAP2K6, TNF
Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha.
Roulston A, et al.
J Biol Chem 273(17):10232-9. 1998
72MAPK8
Defective T cell differentiation in the absence of Jnk1.
Dong, C.; Yang, D. D.; Wysk, M.; Whitmarsh, A. J.; Davis, R. J.; Flavell, R. A.
Science. 282: 2092-2095 1998
73MAP2K7, MAPK8
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase.
Tournier C, Whitmarsh AJ, Cavanagh J, Barrett T, Davis RJ.
Proc Natl Acad Sci U S A 94(14):7337-42. 1997
74MAPK8
JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases.
Hu MC, Qiu WR, Wang YP.
Oncogene. 15(19):2277-87. 1997
75MAPK8
MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases.
Xu S, Cobb MH.
J Biol Chem. 272(51):32056-60. 1997
76MAPK8
Selective interaction of JNK protein kinase isoforms with transcription factors.
Gupta S, et al.
EMBO J 15 : 2760-2770. 1996
77MAPK8
Differential phosphorylations of Spi-B and Spi-1 transcription factors.
Mao C, Ray-Gallet D, Tavitian A, Moreau-Gachelin F.
Oncogene. 12(4):863-73. 1996
78MAPK8
Neither ERK nor JNK/SAPK MAP kinase subtypes are essential for histone H3/HMG-14 phosphorylation or c-fos and c-jun induction.
Cano E, Hazzalin CA, Kardalinou E, Buckle RS, Mahadevan LC.
J Cell Sci. 108 ( Pt 11):3599-609. 1995
79MAPK8, MAP2K4
JNK1 : a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.
Dˇrijard B, et al.
Cell 76 : 1025-1037. 1994