1 | MAPK6, USP20
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| Deubiquitinating Enzyme USP20 Regulates Extracellular Signal-Regulated Kinase 3 Stability and Biological Activity.
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| Mathien S, Déléris P, Soulez M, Voisin L, Meloche S.
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| Mol Cell Biol 37(9). pii: e00432-16. doi: 10.1128/MCB.00432-16. Print 2017 May 1.
2017
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2 | MAPK6, TDP2, TOP2A
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| ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells.
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| Bian K, Muppani NR, Elkhadragy L, Wang W, Zhang C, Chen T, Jung S, Seternes OM, Long W.
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| Oncotarget 7(6):6665-75. doi: 10.18632/oncotarget.6682.
2016
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3 | CCND1, CLDN16, CPE, LRP1B, MAGI3, MAPK6, MATN2, MPPED2, PFKFB2, PTPRE, PYGL, SEMA3D, SERGEF, SLC4A4, TIMP1
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| robust biomarker of differential correlations improves the diagnosis of cytologically indeterminate thyroid cancers
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| Gomez-Rueda H, Palacios-Corona R, Gutiérrez-Hermosillo H, Trevino V. A
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| Int J Mol Med. May;37(5):1355-62. doi: 10.3892/ijmm.2016.2534. Epub 2016 Mar 2016
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4 | HERC2, HIF1AN, MAPK6, NEURL4, UBE3A
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| Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes.
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| Martínez-Noël G, Galligan JT, Sowa ME, Arndt V, Overton TM, Harper JW, Howley PM.
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| Mol Cell Biol 32(15):3095-106. Epub 2012 May 29. 2012
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5 | MAPK4, MAPK6, NCOA3
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| ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.
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| Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Qin J, Tsai SY, Tsai MJ, O'Malley BW.
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| J Clin Invest 122(5):1869-80. doi: 10.1172/JCI61492. Epub 2012 Apr 16. 2012
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6 | MAPK6, PAK2
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| Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity.
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| De la Mota-Peynado A, Chernoff J, Beeser A.
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| J Biol Chem 286(15):13603-11. doi: 10.1074/jbc.M110.181743. Epub 2011 Feb 11.
2011
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7 | MAPK4, MAPK6, MAPKAPK5
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| Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.
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| Déléris P, Rousseau J, Coulombe P, Rodier G, Tanguay PL, Meloche S.
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| J Cell Physiol 217(3):778-88.
2008
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8 | MAPK6
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| Regulation of ERK3/MAPK6 expression by BRAF.
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| Hoeflich KP, Eby MT, Forrest WF, Gray DC, Tien JY, Stern HM, Murray LJ, Davis DP, Modrusan Z, Seshagiri S.
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| Int J Oncol 29(4):839-49.
2006
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9 | MAPK6, MAPKAPK5
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| Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway.
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| Seternes OM, Mikalsen T, Johansen B, Michaelsen E, Armstrong CG, Morrice NA, Turgeon B, Meloche S, Moens U, Keyse SM.
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| EMBO J 23(24):4780-91. Epub 2004 Dec 2. Erratum in: EMBO J. 2005 Feb 23;24(4):873.
2004
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10 | MAPK6
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| Nuclear export of ERK3 by a CRM1-dependent mechanism regulates its inhibitory action on cell cycle progression.
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| Julien C, Coulombe P, Meloche S.
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| J Biol Chem 278(43):42615-24. Epub 2003 Aug 12. 2003
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11 | MAPK6, MAPK6PS1, MAPK6PS2, MAPK6PS3, MAPK6PS4, MAPK6PS5, MAPK6PS6
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| The Protein Kinase ERK3 Is Encoded by a Single Functional Gene: Genomic Analysis of the ERK3 Gene Family.
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| Turgeon B, Lang BF, Meloche S.
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| Genomics 80(6):673-80. 2002
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12 | MAPK6
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| Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa.
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| Turgeon B, Saba-El-Leil MK, Meloche S.
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| Biochem J 346 Pt 1:169-75. 2000
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13 | MAPK6
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| Primary structure, expression and chromosomal locus of a human homolog of rat ERK3.
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| Meloche S, et al.
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| Oncogene 13 : 1575-1579. 1996
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14 | MAPK1, MAPK4, MAPK6, MAPK7
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| ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF.
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| Boulton TG, et al.
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| Cell 65(4):663-75. 1991
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