1 | MAPK4, MAPK6, NCOA3
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| ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.
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| Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Qin J, Tsai SY, Tsai MJ, O'Malley BW.
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| J Clin Invest 122(5):1869-80. doi: 10.1172/JCI61492. Epub 2012 Apr 16. 2012
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2 | MAPK4
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| Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity.
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| De la Mota-Peynado A, Chernoff J, Beeser A.
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| J Biol Chem 286(15):13603-11. doi: 10.1074/jbc.M110.181743. Epub 2011 Feb 11.
2011
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3 | MAPK4, MAPK7, MAPKAPK5
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| Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway.
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| Déléris P, Trost M, Topisirovic I, Tanguay PL, Borden KL, Thibault P, Meloche S.
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| J Biol Chem 286(8):6470-8. doi: 10.1074/jbc.M110.181529. Epub 2010 Dec 22.
2011
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4 | MAPK4, MAPK7
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| Targeted inactivation of Mapk4 in mice reveals specific nonredundant functions of Erk3/Erk4 subfamily mitogen-activated protein kinases.
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| Rousseau J, Klinger S, Rachalski A, Turgeon B, Déléris P, Vigneault E, Poirier-Héon JF, Davoli MA, Mechawar N, El Mestikawy S, Cermakian N, Meloche S.
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| Mol Cell Biol 30(24):5752-63. doi: 10.1128/MCB.01147-10. Epub 2010 Oct 18.
2010
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5 | MAPK4
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| ERK3 is required for metaphase-anaphase transition in mouse oocyte meiosis.
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| Li S, Ou XH, Wang ZB, Xiong B, Tong JS, Wei L, Li M, Yuan J, Ouyang YC, Hou Y, Schatten H, Sun QY.
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| PLoS One 5(9). doi:pii: e13074. 10.1371/journal.pone.0013074.
2010
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6 | MAPK4
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| Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality.
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| Klinger S, Turgeon B, Lévesque K, Wood GA, Aagaard-Tillery KM, Meloche S.
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| Proc Natl Acad Sci U S A 106(39):16710-5. doi: 10.1073/pnas.0900919106. Epub 2009 Sep 15.
2009
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7 | MAPK4, MAPK7
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| Docking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif.
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| Aberg E, Torgersen KM, Johansen B, Keyse SM, Perander M, Seternes OM.
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| J Biol Chem 284(29):19392-401. doi: 10.1074/jbc.M109.023283. Epub 2009 May 27.
2009
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8 | MAPK4, MAPK6, MAPKAPK5
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| Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.
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| Déléris P, Rousseau J, Coulombe P, Rodier G, Tanguay PL, Meloche S.
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| J Cell Physiol 217(3):778-88.
2008
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9 | CDC14A, MAPK4
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| A functional link between the human cell cycle-regulatory phosphatase Cdc14A and the atypical mitogen-activated kinase Erk3.
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| Hansen CA, Bartek J, Jensen S.
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| Cell Cycle 7(3):325-34. Epub 2007 Nov 30.
2008
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10 | MAPK4, CCND3
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| Identification of extracellular signal-regulated kinase 3 as a new interaction partner of cyclin D3.
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| Sun M, Wei Y, Yao L, Xie J, Chen X, Wang H, Jiang J, Gu J.
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| Biochem Biophys Res Commun 340(1):209-14. Epub 2005 Dec 9. 2006
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11 | MAPK4
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| Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.
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| Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M.
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| J Biol Chem 281(46):35511-9. Epub 2006 Sep 13. 2006
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12 | MAPK4
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| Isolation of chromosome 18-specific brain transcripts as positional candidates for bipolar disorder.
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| Yoshikawa T, et al.
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| Am J Med Genet 74 : 140-149. 1997
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13 | MAP3K5, MAP2K1, MAP2K3, MAPK4
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| Chromosomal localization of four MAPK signaling cascade genes : MEK1, MEK3, MEK4 and MEKK5.
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| Rampoldi L, Zimbello R, Bortoluzzi S, Tiso N, Valle G, Lanfranchi G, Danieli GA.
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| Cytogenet Cell Genet 78(3-4):301-3. 1997
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14 | MAPK1, MAPK3, MAPK4
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| Genomic loci of human mitogen-activated protein kinases.
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| Li L, et al.
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| Oncogene 9 : 647-649. 1994
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15 | MAPK1, MAPK3, MAPK4
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| Heterogeneous expression of four MAP kinase isoforms in human tissues.
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| Gonzalez FA, et al.
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| FEBS Lett 304 : 170-178. 1992
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16 | MAPK1, MAPK4, MAPK6, MAPK7
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| ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF.
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| Boulton TG, et al.
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| Cell 65(4):663-75. 1991
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