| 1 | L3MBTL4, MAPK14
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| p38/JNK Is Required for the Proliferation and Phenotype Changes of Vascular Smooth Muscle Cells Induced by L3MBTL4 in Essential Hypertension.
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| Hu C, Zuo K, Li K, Gao Y, Chen M, Hu R, Liu Y, Chi H, Wang H, Qin Y, Liu X, Zhong J, Cai J, Yang X, Li J.
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| Int J Hypertens. Dec 16;2020:3123968. doi: 10.1155/2020/3123968. 2020
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| 2 | EXOC3, HSPB1, HSPB2, MAPK14
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| Sec6 enhances cell migration and suppresses apoptosis by elevating the phosphorylation of p38 MAPK, MK2, and HSP27.
|
| Tanaka T, Iino M, Goto K.
|
| Cell Signal 49:1-16. doi: 10.1016/j.cellsig.2018.04.009. Epub 2018 May 2.
2018
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| 3 | MAPK14, PPP2CA
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| PP2A regulates SCF-induced cardiac stem cell migration through interaction with p38 MAPK.
|
| Wang Y, Xia Y, Kuang D, Duan Y, Wang G.
|
| Life Sci 191:59-67. doi: 10.1016/j.lfs.2017.10.006. Epub 2017 Oct 3.
2017
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| 4 | DSG2, MAPK14
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| Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase.
|
| Ungewiß H, Vielmuth F, Suzuki ST, Maiser A, Harz H, Leonhardt H, Kugelmann D, Schlegel N, Waschke J.
|
| Sci Rep 7(1):6329. doi: 10.1038/s41598-017-06713-y.
2017
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| 5 | CHRM3, EGFR, MAPK14, TNF
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| Activation of muscarinic receptors prevents TNF-α-mediated intestinal epithelial barrier disruption through p38 MAPK.
|
| Uwada J, Yazawa T, Islam MT, Khan MRI, Krug SM, Fromm M, Karaki SI, Suzuki Y, Kuwahara A, Yoshiki H, Sada K, Muramatsu I, Taniguchi T.
|
| Cell Signal 35:188-196. doi: 10.1016/j.cellsig.2017.04.007. Epub 2017 Apr 12.
2017
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| 6 | MAPK14, STAT3, TNFSF18
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| GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis.
|
| Tang X, Tian J, Ma J, Wang J, Qi C, Rui K, Wang Y, Xu H, Lu L, Wang S.
|
| Oncotarget 7(8):8590-600. doi: 10.18632/oncotarget.6535.
2016
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| 7 | AKT1, MAPK14, TNFAIP8L2
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| TIPE2 suppresses the tumorigenesis, growth and metastasis of breast cancer via inhibition of the AKT and p38 signaling pathways.
|
| Zhang Z, Liu L, Liu C, Cao S, Zhu Y, Mei Q.
|
| Oncol Rep 36(6):3311-3316. doi: 10.3892/or.2016.5192.
2016
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| 8 | MAPK14, SNAI1, SUPT20H
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| p38 MAPK mediates epithelial-mesenchymal transition by regulating p38IP and Snail in head and neck squamous cell carcinoma.
|
| Lin Y, Mallen-St Clair J, Wang G, Luo J, Palma-Diaz F, Lai C, Elashoff DA, Sharma S, Dubinett SM, St John M.
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| Oral Oncol. Sep;60:81-9. doi: 10.1016/j.oraloncology.2016.06.010. Epub 2016 Jul 15 2016
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| 9 | MAPK14, SCD
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| Role of p38 mitogen-activated protein kinase in linking stearoyl-CoA desaturase-1 activity with endoplasmic reticulum homeostasis.
|
| Koeberle A, Pergola C, Shindou H, Koeberle SC, Shimizu T, Laufer SA, Werz O.
|
| FASEB J 29(6):2439-49. doi: 10.1096/fj.14-268474. Epub 2015 Feb 12.
2015
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| 10 | FNDC5, MAPK14, PRKAA1
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| Irisin, a Novel Myokine, Regulates Glucose Uptake in Skeletal Muscle Cells via AMPK.
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| Lee HJ, Lee JO, Kim N, Kim JK, Kim HI, Lee YW, Kim SJ, Choi JI, Oh Y, Kim JH, Suyeon-Hwang, Park SH, Kim HS.
|
| Mol Endocrinol 29(6):873-81. doi: 10.1210/me.2014-1353. Epub 2015 Mar 31.
2015
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| 11 | MAPK14, MMP9, PGF
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| Placental growth factor promotes metastases of non-small cell lung cancer through MMP9.
|
| Zhang W, Zhang T, Lou Y, Yan B, Cui S, Jiang L, Han B.
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| Cell Physiol Biochem 37(3):1210-8. doi: 10.1159/000430244. Epub 2015 Sep 30.
2015
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| 12 | MAPK14, NCF1, PIN1, TLR8
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| TLR8, but not TLR7, induces the priming of the NADPH oxidase activation in human neutrophils.
|
| Makni-Maalej K, Marzaioli V, Boussetta T, Belambri SA, Gougerot-Pocidalo MA, Hurtado-Nedelec M, Dang PM, El-Benna J.
|
| J Leukoc Biol 97(6):1081-7. doi: 10.1189/jlb.2A1214-623R.
2015
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| 13 | AKT1, MAPK14, NFKBIA, TNFAIP8L2
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| TIPE2 Inhibits Lung Cancer Growth Attributing to Promotion of Apoptosis by Regulating Some Apoptotic Molecules Expression.
|
| Liu QQ, Zhang FF, Wang F, Qiu JH, Luo CH, Zhu GY, Liu YF.
|
| PLoS One 10(5):e0126176. doi: 10.1371/journal.pone.0126176.
2015
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| 14 | MAPK1, MAPK14, RAB9A, RAB9B
|
| Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways.
|
| Hirota Y, Yamashita S, Kurihara Y, Jin X, Aihara M, Saigusa T, Kang D, Kanki T.
|
| Autophagy 11(2):332-43. doi: 10.1080/15548627.2015.1023047.
2015
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| 15 | ARG2, MAPK14, RPS6KB1
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| Role of p38 mitogen-activated protein kinase in vascular endothelial aging: interaction with Arginase-II and S6K1 signaling pathway.
|
| Wu Z, Yu Y, Liu C, Xiong Y, Montani JP, Yang Z, Ming XF.
|
| Aging (Albany NY) 7(1):70-81.
2015
|
| 16 | GATA4, GSN, MAPK14, NPPB
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| Gelsolin (GSN) induces cardiomyocyte hypertrophy and BNP expression via p38 signaling and GATA-4 transcriptional factor activation.
|
| Hu WS, Ho TJ, Pai P, Chung LC, Kuo CH, Chang SH, Tsai FJ, Tsai CH, Jie YC, Liou YM, Huang CY.
|
| Mol Cell Biochem 390(1-2):263-70. doi: 10.1007/s11010-014-1977-7. Epub 2014 Feb 7.
2014
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| 17 | ATP1A1, MAPK14
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| Sodium transport is modulated by p38 kinase-dependent cross-talk between ENaC and Na,K-ATPase in collecting duct principal cells.
|
| Wang YB, Leroy V, Maunsbach AB, Doucet A, Hasler U, Dizin E, Ernandez T, de Seigneux S, Martin PY, Féraille E.
|
| J Am Soc Nephrol 25(2):250-9. doi: 10.1681/ASN.2013040429. Epub 2013 Oct 31.
2014
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| 18 | MAPK14, NOS2
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| IGF-1 induces iNOS expression via the p38 MAPK signal pathway in the anti-apoptotic process in pulmonary artery smooth muscle cells during PAH.
|
| Jin C, Guo J, Qiu X, Ma K, Xiang M, Zhu X, Guo J.
|
| J Recept Signal Transduct Res 34(4):325-31. doi: 10.3109/10799893.2014.903417. Epub 2014 Mar 27.
2014
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| 19 | GATA1, MAPK14, RPS19
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| TNF-mediated inflammation represses GATA1 and activates p38 MAP kinase in RPS19-deficient hematopoietic progenitors
|
| Bibikova E, Youn MY, Danilova N, Ono-Uruga Y, Konto-Ghiorghi Y, Ochoa R, Narla A, Glader B, Lin S, Sakamoto KM.
|
| Blood. Dec 11;124(25):3791-8. doi: 10.1182/blood-2014-06-584656. Epub 2014 Sep 30. 2014
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| 20 | KAT5, MAPK14, MAPKAPK5
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| A posttranslational modification cascade involving p38, Tip60, and PRAK mediates oncogene-induced senescence.
|
| Zheng H, Seit-Nebi A, Han X, Aslanian A, Tat J, Liao R, Yates JR 3rd, Sun P.
|
| Mol Cell 50(5):699-710. doi: 10.1016/j.molcel.2013.04.013. Epub 2013 May 16.
2013
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| 21 | CDKN1A, MAPK14
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| A role for p38 in transcriptional elongation of p21 (CIP1) in response to Aurora B inhibition.
|
| Kumari G, Ulrich T, Gaubatz S.
|
| Cell Cycle 12(13):2051-60. doi: 10.4161/cc.25100. Epub 2013 Jun 6.
2013
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| 22 | CASP3, CASP9, MAPK14, ROBO2, SLIT1
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| Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization.
|
| Campbell DS, Okamoto H.
|
| J Cell Biol 203(4):657-72. doi: 10.1083/jcb.201303072.
2013
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| 23 | GADD45B, MAP3K4, MAPK14
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| Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.
|
| Keil E, Höcker R, Schuster M, Essmann F, Ueffing N, Hoffman B, Liebermann DA, Pfeffer K, Schulze-Osthoff K, Schmitz I.
|
| Cell Death Differ 20(2):321-32. doi: 10.1038/cdd.2012.129. Epub 2012 Oct 12.
2013
|
| 24 | MAP3K10, MAP3K4, MAPK14
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| The TGFβ-induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1
|
| Sapkota GP.
|
| Open Biol. Jun 12;3(6):130067. doi: 10.1098/rsob.130067. 2013
|
| 25 | MAPK14
|
| Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation.
|
| Huang G, Wang Y, Vogel P, Kanneganti TD, Otsu K, Chi H.
|
| Nat Immunol 13(2):152-61. doi: 10.1038/ni.2207.
2012
|
| 26 | DNAJC3, ERP29, MAPK14
|
| ERp29 induces breast cancer cell growth arrest and survival through modulation of activation of p38 and upregulation of ER stress protein p58IPK.
|
| Gao D, Bambang IF, Putti TC, Lee YK, Richardson DR, Zhang D.
|
| Lab Invest 92(2):200-13. doi: 10.1038/labinvest.2011.163. Epub 2011 Nov 7.
2012
|
| 27 | MAPK14, PXN
|
| Paxillin phosphorylation by JNK and p38 is required for NFAT activation.
|
| Lee YC, Chang AY, Lin-Feng MH, Tsou WI, Chiang IH, Lai MZ.
|
| Eur J Immunol 42(8):2165-75. doi: 10.1002/eji.201142192.
2012
|
| 28 | MAPK14, PDGFB, SERPINA12
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| A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells.
|
| Phalitakul S, Okada M, Hara Y, Yamawaki H.
|
| Biochem Biophys Res Commun 423(4):844-9. doi: 10.1016/j.bbrc.2012.06.052. Epub 2012 Jun 17.
2012
|
| 29 | MAPK14, SOX6, ZAK
|
| The protein kinase MLTK regulates chondrogenesis by inducing the transcription factor Sox6.
|
| Suzuki T, Kusakabe M, Nakayama K, Nishida E.
|
| Development 139(16):2988-98. doi: 10.1242/dev.078675. Epub 2012 Jul 4.
2012
|
| 30 | MAPK14, OPRK1
|
| Ligand directed signaling differences between rodent and human κ-opioid receptors.
|
| Schattauer SS, Miyatake M, Shankar H, Zietz C, Levin JR, Liu-Chen LY, Gurevich VV, Rieder MJ, Chavkin C.
|
| J Biol Chem 287(50):41595-607. doi: 10.1074/jbc.M112.381368. Epub 2012 Oct 19.
2012
|
| 31 | MAPK14, MMP13, S100A12
|
| Role of S100A12 in the pathogenesis of osteoarthritis.
|
| Nakashima M, Sakai T, Hiraiwa H, Hamada T, Omachi T, Ono Y, Inukai N, Ishizuka S, Matsukawa T, Oda T, Takamatsu A, Yamashita S, Ishiguro N.
|
| Biochem Biophys Res Commun 422(3):508-14. doi: 10.1016/j.bbrc.2012.05.036. Epub 2012 May 16.
2012
|
| 32 | MAPK14, MYCBP2, TRPV1
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| The ubiquitin ligase MYCBP2 regulates transient receptor potential vanilloid receptor 1 (TRPV1) internalization through inhibition of p38 MAPK signaling.
|
| Holland S, Coste O, Zhang DD, Pierre SC, Geisslinger G, Scholich K.
|
| J Biol Chem 286(5):3671-80. Epub 2010 Nov 23.
2011
|
| 33 | ATF6, ATF6B, MAPK14
|
| The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal death.
|
| Egawa N, Yamamoto K, Inoue H, Hikawa R, Nishi K, Mori K, Takahashi R.
|
| J Biol Chem 286(10):7947-57. Epub 2010 Dec 3.
2011
|
| 34 | MAPK14
|
| p38 MAPK regulates G1-S transition in hypoxic cardiac fibroblasts.
|
| Pillai MS, Sapna S, Shivakumar K.
|
| Int J Biochem Cell Biol 43(6):919-27. Epub 2011 Mar 21.
2011
|
| 35 | MAPK14
|
| A novel cardioprotective p38-MAPK/mTOR pathway.
|
| Hernández G, Lal H, Fidalgo M, Guerrero A, Zalvide J, Force T, Pombo CM.
|
| Exp Cell Res 317(20):2938-49. Epub 2011 Oct 2.
2011
|
| 36 | MAPK14
|
| p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis.
|
| Lee J, Sun C, Zhou Y, Lee J, Gokalp D, Herrema H, Park SW, Davis RJ, Ozcan U.
|
| Nat Med 17(10):1251-60. doi: 10.1038/nm.2449.
2011
|
| 37 | CDON, GAS1, MAPK14
|
| Gas1 cooperates with Cdo and promotes myogenic differentiation via activation of p38MAPK.
|
| Leem YE, Han JW, Lee HJ, Ha HL, Kwon YL, Ho SM, Kim BG, Tran P, Bae GU, Kang JS.
|
| Cell Signal 23(12):2021-9. Epub 2011 Jul 24.
2011
|
| 38 | MAPK14
|
| Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ).
|
| Bachstetter AD, Xing B, de Almeida L, Dimayuga ER, Watterson DM, Van Eldik LJ.
|
| J Neuroinflammation 8:79.
2011
|
| 39 | MAPK14
|
| p38 MAPK controls prothrombin expression by regulated RNA 3' end processing.
|
| Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Gröne HJ, Schirmacher P, Hentze MW, Kulozik AE.
|
| Mol Cell 41(3):298-310.
2011
|
| 40 | CDK5RAP3, MAPK14
|
| LZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1).
|
| An H, Lu X, Liu D, Yarbrough WG.
|
| PLoS One 6(1):e16427.
2011
|
| 41 | MAPK14
|
| Inhibition of p38 mitogen-activated protein kinase promotes ex vivo hematopoietic stem cell expansion.
|
| Wang Y, Kellner J, Liu L, Zhou D.
|
| Stem Cells Dev 20(7):1143-52. Epub 2011 Feb 24.
2011
|
| 42 | FLT3, MAPK14
|
| FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.
|
| Desterke C, Bilhou-Nabéra C, Guerton B, Martinaud C, Tonetti C, Clay D, Guglielmelli P, Vannucchi A, Bordessoule D, Hasselbalch H, Dupriez B, Benzoubir N, Bourgeade MF, Pierre-Louis O, Lazar V, Vainchenker W, Bennaceur-Griscelli A, Gisslinger H, Giraudier S, Le Bousse-Kerdilès MC; French Intergroup of Myeloproliferative Disorders,; French INSERM; European EUMNET Networks on Myelofibrosis.
|
| Cancer Res 71(8):2901-15. doi: 10.1158/0008-5472.CAN-10-1731. Epub 2011 Apr 12. Erratum in: Cancer Res. 2011 Jun 1;71(11):4049-50.
2011
|
| 43 | MAPK14
|
| The p38 SAPK is recruited to chromatin via its interaction with transcription factors.
|
| Ferreiro I, Barragan M, Gubern A, Ballestar E, Joaquin M, Posas F.
|
| J Biol Chem 285(41):31819-28. Epub 2010 Aug 3.
2010
|
| 44 | MAPK14
|
| p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition.
|
| Strippoli R, Benedicto I, Foronda M, Perez-Lozano ML, Sánchez-Perales S, López-Cabrera M, Del Pozo MÁ.
|
| J Cell Sci 123(Pt 24):4321-31. Epub 2010 Nov 23.
2010
|
| 45 | MAPK14, SP7
|
| p38 regulates expression of osteoblast-specific genes by phosphorylation of osterix.
|
| Ortuño MJ, Ruiz-Gaspà S, Rodríguez-Carballo E, Susperregui AR, Bartrons R, Rosa JL, Ventura F.
|
| J Biol Chem 285(42):31985-94. Epub 2010 Aug 3.
2010
|
| 46 | MAPK14
|
| Epithelial p38alpha controls immune cell recruitment in the colonic mucosa.
|
| Kang YJ, Otsuka M, van den Berg A, Hong L, Huang Z, Wu X, Zhang DW, Vallance BA, Tobias PS, Han J.
|
| PLoS Pathog 6(6):e1000934.
2010
|
| 47 | MAPK14
|
| P38 mitogen-activated protein kinase activity is required during mitosis for timely satisfaction of the mitotic checkpoint but not for the fidelity of chromosome segregation.
|
| Lee K, Kenny AE, Rieder CL.
|
| Mol Biol Cell 21(13):2150-60. Epub 2010 May 12.
2010
|
| 48 | MAPK14
|
| p38alpha is required for ovarian cancer cell metabolism and survival.
|
| Matrone A, Grossi V, Chiacchiera F, Fina E, Cappellari M, Caringella AM, Di Naro E, Loverro G, Simone C.
|
| Int J Gynecol Cancer 20(2):203-11.
2010
|
| 49 | MAPK14, MAPKAPK2
|
| p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratins.
|
| Menon MB, Schwermann J, Singh AK, Franz-Wachtel M, Pabst O, Seidler U, Omary MB, Kotlyarov A, Gaestel M.
|
| J Biol Chem 285(43):33242-51. Epub 2010 Aug 19.
2010
|
| 50 | MAPK14, PSMD1
|
| Osmotic stress inhibits proteasome by p38 MAPK-dependent phosphorylation.
|
| Lee SH, Park Y, Yoon SK, Yoon JB.
|
| J Biol Chem 285(53):41280-9. doi: 10.1074/jbc.M110.182188. Epub 2010 Nov 2.
2010
|
| 51 | CYBA, MAPK14, NOX4
|
| Nox4 overexpression activates reactive oxygen species and p38 MAPK in human endothelial cells.
|
| Goettsch C, Goettsch W, Muller G, Seebach J, Schnittler HJ, Morawietz H.
|
| Biochem Biophys Res Commun iochem Biophys Res Commun. 2009 Jan 23. [Epub ahead of print]
2009
|
| 52 | CREB1, MAPK14
|
| Regulation of CREB activation by p38 mitogen activated protein kinase during human primary erythroblast differentiation.
|
| Di Giacomo V, Sancilio S, Caravatta L, Rana RA, Di Pietro R, Cataldi A.
|
| Int J Immunopathol Pharmacol 22(3):679-88.PMID: 19822084 2009
|
| 53 | MAFA, MAPK14
|
| p38 MAPK is a major regulator of MafA protein stability under oxidative stress.
|
| Kondo T, El Khattabi I, Nishimura W, Laybutt DR, Geraldes P, Shah S, King G, Bonner-Weir S, Weir G, Sharma A.
|
| Mol Endocrinol 23(8):1281-90. doi: 10.1210/me.2008-0482. Epub 2009 Apr 30.
2009
|
| 54 | GSK3B, MAPK14
|
| Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.
|
| Thornton TM, Pedraza-Alva G, Deng B, Wood CD, Aronshtam A, Clements JL, Sabio G, Davis RJ, Matthews DE, Doble B, Rincon M.
|
| Science 320(5876):667-70. 2008
|
| 55 | MAPK14, SMAD7
|
| Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways.
|
| Iwai T, Murai J, Yoshikawa H, Tsumaki N.
|
| J Biol Chem 283(40):27154-64. Epub 2008 Jul 21. 2008
|
| 56 | MAPK14
|
| p38 MAPK regulates COPII recruitment.
|
| Wang L, Lucocq JM.
|
| Biochem Biophys Res Commun 363(2):317-21. Epub 2007 Sep 7. 2007
|
| 57 | NDRG2, SOCS1, STAT3, MAPK14
|
| SOCS1 induced by NDRG2 expression negatively regulates STAT3 activation in breast cancer cells.
|
| Park Y, Shon SK, Kim A, Kim KI, Yang Y, Cho DH, Lee MS, Lim JS.
|
| Biochem Biophys Res Commun 363(2):361-7. Epub 2007 Sep 14. 2007
|
| 58 | MAPK12, MAPK14
|
| Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.
|
| Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, Baeza-Raja B, Jardí M, Bosch-Comas A, Esteller M, Caelles C, Serrano AL, Wagner EF, Muñoz-Cánoves P.
|
| EMBO J 26(5):1245-56. Epub 2007 Feb 15.
2007
|
| 59 | MAPK14, PBK
|
| PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response.
|
| Ayllón V, O'connor R.
|
| Oncogene 26(24):3451-61. Epub 2006 Dec 11.
2007
|
| 60 | CSK, MAPK14, SRC
|
| Suppression of c-Src activity stimulates muscle differentiation via p38 MAPK activation.
|
| Lim MJ, Seo YH, Choi KJ, Cho CH, Kim BS, Kim YH, Lee J, Lee H, Jung CY, Ha J, Kang I, Kim SS.
|
| Arch Biochem Biophys 465(1):197-208. Epub 2007 Jun 12. 2007
|
| 61 | FGF1, MAPK14
|
| FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction.
|
| Engel FB, Hsieh PC, Lee RT, Keating MT.
|
| Proc Natl Acad Sci U S A 103(42):15546-51. Epub 2006 Oct 10. 2006
|
| 62 | MAPK14, FLNA, SP1
|
| Role of p38 in stress activation of Sp1.
|
| D'Addario M, Arora PD, McCulloch CA.
|
| Gene 379:51-61. Epub 2006 May 4. 2006
|
| 63 | BCL2L11,MAPK14
|
| p38-MAP kinase activation followed by BIM induction is essential for glucocorticoid-induced apoptosis in lymphoblastic leukemia cells.
|
| Lu J, Quearry B, Harada H.
|
| FEBS Lett 580(14):3539-44. Epub 2006 May 19. 2006
|
| 64 | IL1A, MAPK14
|
| p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes.
|
| Radons J, Bosserhoff AK, GrŠssel S, Falk W, Schubert TE.
|
| Int J Mol Med 17(4):661-8. 2006
|
| 65 | MAPK14, TEAD1, CEBPB
|
| TEF-1 and C/EBPbeta are major p38alpha MAPK-regulated transcription factors in proliferating cardiomyocytes.
|
| Ambrosino C, Iwata T, Scafoglio C, Mallardo M, Klein R, Nebreda AR.
|
| Biochem J 396(1):163-72. 2006
|
| 66 | CTGF, MAPK14
|
| Roles of PKC, PI3K and JNK in multiple transduction of CCN2/CTGF signals in chondrocytes.
|
| Yosimichi G, Kubota S, Nishida T, Kondo S, Yanagita T, Nakao K, Takano-Yamamoto T, Takigawa M.
|
| Bone 38(6):853-63. Epub 2006 Jan 23. 2006
|
| 67 | DDX53, MAPK14
|
| CAGE, a novel cancer/testis antigen gene, promotes cell motility by activation ERK and p38 MAPK and downregulating ROS.
|
| Shim H, Shim E, Lee H, Hahn J, Kang D, Lee YS, Jeoung D.
|
| Mol Cells 21(3):367-75. 2006
|
| 68 | AT2, MAPK14, MAPKAP1
|
| Sin1 binds to both ATF-2 and p38 and enhances ATF-2-dependent transcription in an SAPK signaling pathway.
|
| Makino C, Sano Y, Shinagawa T, Millar JB, Ishii S.
|
| Genes Cells 11(11):1239-51.
2006
|
| 69 | PELI3, MAPK14
|
| Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner.
|
| Butler MP, Hanly JA, Moynagh PN.
|
| J Biol Chem 280(30):27759-68. Epub 2005 May 25. 2005
|
| 70 | MAPK14, MAP3K4, SH3KBP1
|
| CIN85 regulates the ability of MEKK4 to activate the p38 MAP kinase pathway.
|
| Aissouni Y, Zapart G, Iovanna JL, Dikic I, Soubeyran P.
|
| Biochem Biophys Res Commun 338(2):808-14. Epub 2005 Oct 18. 2005
|
| 71 | MAP2K3, MAP2K6, MAPK14
|
| Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes.
|
| Inoue T, Hammaker D, Boyle DL, Firestein GS.
|
| J Immunol 174(7):4301-6.
2005
|
| 72 | SLC9A3, EZR, MAPK14
|
| Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport.
|
| Zhao H, Shiue H, Palkon S, Wang Y, Cullinan P, Burkhardt JK, Musch MW, Chang EB, Turner JR.
|
| Proc Natl Acad Sci U S A 101(25):9485-90. Epub 2004 Jun 14. 2004
|
| 73 | MAPK14, MEF2C
|
| p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation.
|
| Stanton LA, Sabari S, Sampaio AV, Underhill TM, Beier F.
|
| Biochem J 378(Pt 1):53-62. 2004
|
| 74 | MAPK14, HBP1
|
| The HBP1 transcriptional repressor and the p38 MAP kinase: unlikely partners in G1 regulation and tumor suppression.
|
| Yee AS, Paulson EK, McDevitt MA, Rieger-Christ K, Summerhayes I, Berasi SP, Kim J, Huang CY, Zhang X.
|
| Gene 336(1):1-13. Review. 2004
|
| 75 | MAPK14, NLK, TAB1
|
| The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling.
|
| Ishitani T, Kishida S, Hyodo-Miura J, Ueno N, Yasuda J, Waterman M, Shibuya H, Moon RT, Ninomiya-Tsuji J, Matsumoto K.
|
| Mol Cell Biol 23(1):131-9. 2003
|
| 76 | MAP3K7, MAPK14, TAB1
|
| TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1.
|
| Ge B, Xiong X, Jing Q, Mosley JL, Filose A, Bian D, Huang S, Han J.
|
| J Biol Chem 278(4):2286-93. Epub 2002 Nov 11. 2003
|
| 77 | MAPKAPK5, MAPK14
|
| Regulation of PRAK subcellular location by p38 MAP kinases.
|
| New L, Jiang Y, Han J.
|
| Mol Biol Cell 14(6):2603-16. Epub 2003 Mar 20. 2003
|
| 78 | MAPK14, TAB1
|
| MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha.
|
| Ge B, Gram H, Di Padova F, Huang B, New L, Ulevitch RJ, Luo Y, Han J.
|
| Science 295(5558):1291-4. 2002
|
| 79 | BAK1, CDKN1A, CPNE5, GLO1, HKE@, HMGA1, KIFC1, MAPK14, PPIL1, RPS10, TCTE1, ZNF76
|
| Physical map of human 6p21.2-6p21.3 : region flanking the centromeric end of the major histocompatibility complex.
|
| Tripodis N, et al.
|
| Genome Res 8 : 631-643. 1998
|
| 80 | MAPK14
|
| Localization of the human stress responsive MAP kinase-like CSAIDs binding protein (CSBP) gene to chromosome 6p21.3/21.2.
|
| McDonnell PC, et al.
|
| Genomics 29 : 301-302. 1995
|
| 81 | MAPK14
|
| A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.
|
| Rouse J, et al.
|
| Cell 78 : 1027-1037. 1994
|
| 82 | MAPK14
|
| A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.
|
| Lee JC, et al.
|
| Nature 372 : 739-746. 1994
|