| 1 | MAP3K14, SMG1
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| SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds.
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| Cheung HH, St Jean M, Beug ST, Lejmi-Mrad R, LaCasse E, Baird SD, Stojdl DF, Screaton RA, Korneluk RG.
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| Cell Death Dis 2:e146.
2011
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| 2 | MAP3K14, RELB
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| NIK is involved in constitutive activation of the alternative NF-kappaB pathway and proliferation of pancreatic cancer cells.
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| Nishina T, Yamaguchi N, Gohda J, Semba K, Inoue J.
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| Biochem Biophys Res Commun 388(1):96-101. Epub 2009 Jul 29.
2009
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| 3 | MAP3K14, MAP3K8
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| NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation.
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| Wittwer T, Schmitz ML.
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| Biochem Biophys Res Commun 371(2):294-7. Epub 2008 Apr 23.
2008
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| 4 | MAP3K14, RCAN1
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| NF-kappaB-inducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1.
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| Lee EJ, Seo SR, Um JW, Park J, Oh Y, Chung KC.
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| J Biol Chem 283(6):3392-400. Epub 2007 Dec 4.
2008
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| 5 | MAP3K14
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| The endogenous reactive oxygen species promote NF-kappaB activation by targeting on activation of NF-kappaB-inducing kinase in oral squamous carcinoma cells.
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| Wang Y, Huang X, Cang H, Gao F, Yamamoto T, Osaki T, Yi J.
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| Free Radic Res 41(9):963-71.
2007
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| 6 | MAP3K14, STAT3
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| LIGHT, a member of the TNF superfamily, activates Stat3 mediated by NIK pathway.
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| Nadiminty N, Chun JY, Hu Y, Dutt S, Lin X, Gao AC.
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| Biochem Biophys Res Commun 359(2):379-84. Epub 2007 May 25.
2007
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| 7 | MAP3K14
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| Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase.
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| Li Q, Engelhardt JF.
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| J Biol Chem 281(3):1495-505. Epub 2005 Nov 14.
2006
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| 8 | MAP3K14, TRAF2
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| Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival.
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| Yang CH, Murti A, Pfeffer LM.
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| J Biol Chem 280(36):31530-6. Epub 2005 Jul 11.
2005
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| 9 | MAP3K14, TNAP
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| TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activation.
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| Hu WH, Mo XM, Walters WM, Brambilla R, Bethea JR.
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| J Biol Chem 279(34):35975-83. Epub 2004 Jun 18.
2004
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| 10 | MAP3K14
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| Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-kappaB inducing kinase NIK.
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| Birbach A, Bailey ST, Ghosh S, Schmid JA.
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| J Cell Sci 117(Pt 16):3615-24.
2004
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| 11 | MAP3K14, TRAF3
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| Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.
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| Liao G, Zhang M, Harhaj EW, Sun SC.
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| J Biol Chem 279(25):26243-50. Epub 2004 Apr 14.
2004
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| 12 | MAP3K14
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| NIK is a component of the EGF/heregulin receptor signaling complexes.
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| Chen D, Xu LG, Chen L, Li L, Zhai Z, Shu HB.
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| Oncogene 22(28):4348-55.
2003
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| 13 | MAP3K14, PEBP1
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| Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation.
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| Yeung KC, Rose DW, Dhillon AS, Yaros D, Gustafsson M, Chatterjee D, McFerran B, Wyche J, Kolch W, Sedivy JM.
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| Mol Cell Biol 21(21):7207-17.
2001
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| 14 | MAP3K14
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| Hiv-1 Tat can substantially enhance the capacity of NIK to induce IkappaB degradation.
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| Li X, Josef J, Marasco WA.
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| Biochem Biophys Res Commun 286(3):587-94.
2001
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| 15 | MAP3K7, MAP3K14
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| The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.
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| Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K.
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| Nature 398(6724):252-6. 1999
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| 16 | FMNL1,FTDP17,MAP3K14
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| The NIK protein kinase and C17orf1 genes : chromosomal mapping, gene structures and mutational screening in frontotemporal dementia and parkinsonism linked to chromosome 17.
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| Aronsson FC, et al.
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| Hum Genet 103 : 340-345. 1998
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| 17 | MAP3K14, MAP3K7
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| TGF-beta-activated kinase 1 stimulates NF-kappa B activation by an NF-kappa B-inducing kinase-independent mechanism.
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| Sakurai H, Shigemori N, Hasegawa K, Sugita T.
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| Biochem Biophys Res Commun 243(2):545-9. 1998
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| 18 | MAP3K14
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| Molecular determinants of NF-kappaB-inducing kinase action.
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| Lin X, Mu Y, Cunningham ET Jr, Marcu KB, Geleziunas R, Greene WC.
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| Mol Cell Biol 18(10):5899-907. 1998
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| 19 | MAP3K14
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| MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.
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| Malinin NL, et al.
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| Nature 385 : 540-544. 1997
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