1 | MAP2K3, MAP2K6
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| Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL.
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| Huang H, Ryu J, Ha J, Chang EJ, Kim HJ, Kim HM, Kitamura T, Lee ZH, Kim HH.
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| Cell Death Differ 13(11):1879-91. Epub 2006 Feb 24.
2006
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2 | MAP2K3, MAP2K6, MAPK14
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| Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes.
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| Inoue T, Hammaker D, Boyle DL, Firestein GS.
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| J Immunol 174(7):4301-6.
2005
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3 | MAP2K1, MAP2K3, MAP2K4, MAP2K6, MAP2K7, MAP3K1, MAP3K4
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| Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.
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| Takekawa M, Tatebayashi K, Saito H.
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| Mol Cell 18(3):295-306.
2005
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4 | DYRK1B, MAP2K3, PCBD2
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| Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
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| Lim S, Jin K, Friedman E.
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| J Biol Chem 277(28):25040-6. Epub 2002 Apr 29. Erratum in: J Biol Chem. 2004 Feb 6;279(6):5047. 2002
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5 | MAP2K3
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| Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression.
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| Wysk M, et al.
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| Proc Natl Acad Sci U S A 96(7):3763-8. 1999
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6 | MAP3K5, MAP2K1, MAP2K3, MAPK4
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| Chromosomal localization of four MAPK signaling cascade genes : MEK1, MEK3, MEK4 and MEKK5.
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| Rampoldi L, Zimbello R, Bortoluzzi S, Tiso N, Valle G, Lanfranchi G, Danieli GA.
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| Cytogenet Cell Genet 78(3-4):301-3. 1997
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7 | MAP2K3
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| Identification and characterization of a predominant isoform of human MKK3.
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| Han J, et al.
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| FEBS Lett 403 : 19-22. 1997
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8 | MAP2K3, MAP2K6
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| MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.
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| Raingeaud J, et al.
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| Mol Cell Biol 16(3):1247-55. 1996
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9 | MAP2K3, MAP2K6
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| Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells.
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| Cuenda A, Alonso G, Morrice N, Jones M, Meier R, Cohen P, Nebreda AR.
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| EMBO J 15(16):4156-64. 1996
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