| 1 | AMCN5, MAGEL2
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| Truncating Mutations of MAGEL2, a Gene within the Prader-Willi Locus, Are Responsible for Severe Arthrogryposis.
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| Mejlachowicz D, Nolent F, Maluenda J, Ranjatoelina-Randrianaivo H, Giuliano F, Gut I, Sternberg D, Laquerrière A, Melki J.
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| Am J Hum Genet 97(4):616-20. doi: 10.1016/j.ajhg.2015.08.010. Epub 2015 Sep 10.
2015
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| 2 | CBX4, MAGED1, MAGEF1, MAGEL2, NDN, NSMCE2, PIAS1, STAT1
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| Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.
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| Gur I, Fujiwara K, Hasegawa K, Yoshikawa K.
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| PLoS One 9(6):e99503. doi: 10.1371/journal.pone.0099503. eCollection 2014. 2014
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| 3 | MAGEL2, PWLAD
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| Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism.
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| Schaaf CP, Gonzalez-Garay ML, Xia F, Potocki L, Gripp KW, Zhang B, Peters BA, McElwain MA, Drmanac R, Beaudet AL, Caskey CT, Yang Y.
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| Nat Genet 45(11):1405-8. doi: 10.1038/ng.2776. Epub 2013 Sep 29.
2013
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| 4 | MAGEL2, PWS
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| Magel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in mice.
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| Mercer RE, Michaelson SD, Chee MJ, Atallah TA, Wevrick R, Colmers WF.
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| PLoS Genet 9(1):e1003207. doi: 10.1371/journal.pgen.1003207. Epub 2013 Jan 17.
2013
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| 5 | MAGEL2, TRIM27, VPS26A, VPS35
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| Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination.
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| Hao YH, Doyle JM, Ramanathan S, Gomez TS, Jia D, Xu M, Chen ZJ, Billadeau DD, Rosen MK, Potts PR.
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| Cell 152(5):1051-64. doi: 10.1016/j.cell.2013.01.051.
2013
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| 6 | MAGED1, MAGEL2, NDN, OXT
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| Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus.
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| Dombret C, Nguyen T, Schakman O, Michaud JL, Hardin-Pouzet H, Bertrand MJ, De Backer O.
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| Hum Mol Genet 21(21):4703-17. doi: 10.1093/hmg/dds310. Epub 2012 Aug 2.
2012
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| 7 | MAGEL2
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| Magel2, a Prader-Willi syndrome candidate gene, modulates the activities of circadian rhythm proteins in cultured cells.
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| Devos J, Weselake SV, Wevrick R.
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| J Circadian Rhythms 9(1):12. doi: 10.1186/1740-3391-9-12.
2011
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| 8 | MAGEL2, PWS
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| Impaired hypothalamic regulation of endocrine function and delayed counterregulatory response to hypoglycemia in Magel2-null mice.
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| Tennese AA, Wevrick R.
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| Endocrinology 152(3):967-78. doi: 10.1210/en.2010-0709. Epub 2011 Jan 19.
2011
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| 9 | MAGEL2
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| A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene.
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| Schaller F, Watrin F, Sturny R, Massacrier A, Szepetowski P, Muscatelli F.
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| Hum Mol Genet 19(24):4895-905. doi: 10.1093/hmg/ddq424. Epub 2010 Sep 28.
2010
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| 10 | MAGEL2, MKRN3, NDN, PWS
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| A paternal deletion of MKRN3, MAGEL2 and NDN does not result in Prader-Willi syndrome.
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| Kanber D, Giltay J, Wieczorek D, Zogel C, Hochstenbach R, Caliebe A, Kuechler A, Horsthemke B, Buiting K.
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| Eur J Hum Genet 17(5):582-90. Epub 2008 Dec 10.
2009
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| 11 | MAGEL2
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| Loss of magel2, a candidate gene for features of Prader-Willi syndrome, impairs reproductive function in mice.
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| Mercer RE, Wevrick R.
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| PLoS One 4(1):e4291. doi: 10.1371/journal.pone.0004291. Epub 2009 Jan 27.
2009
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| 12 | MAGEL2, PWS
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| Inactivation of the mouse Magel2 gene results in growth abnormalities similar to Prader-Willi syndrome.
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| Bischof JM, Stewart CL, Wevrick R.
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| Hum Mol Genet 16(22):2713-9. Epub 2007 Aug 29. 2007
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| 13 | MAGEL2
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| The imprinted gene Magel2 regulates normal circadian output.
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| Kozlov SV, Bogenpohl JW, Howell MP, Wevrick R, Panda S, Hogenesch JB, Muglia LJ, Van Gelder RN, Herzog ED, Stewart CL.
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| Nat Genet 39(10):1266-72. Epub 2007 Sep 23. 2007
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| 14 | BBS4, MAGEL2, NDN, PWS
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| Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth.
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| Lee S, Walker CL, Karten B, Kuny SL, Tennese AA, O'Neill MA, Wevrick R.
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| Hum Mol Genet 14(5):627-37. Epub 2005 Jan 13. 2005
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| 15 | MAGEL2, PWS
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| Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype.
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| Lee S, Kozlov S, Hernandez L, Chamberlain SJ, Brannan CI, Stewart CL, Wevrick R.
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| Hum Mol Genet 9(12):1813-9. 2000
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| 16 | MAGEL2, PWS
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| The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the prader-willi region.
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| Boccaccio I, Glatt-Deeley H, Watrin F, Roeckel N, Lalande M, Muscatelli F.
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| Hum Mol Genet 8(13):2497-505 1999
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