| 1 | LMO7, MAD1L1
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| LMO7 exerts an effect on mitosis progression and the spindle assembly checkpoint.
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| Tzeng YW, Li DY, Chen Y, Yang CH, Chang CY, Juang YL.
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| Int J Biochem Cell Biol 94:22-30. doi: 10.1016/j.biocel.2017.11.006. Epub 2017 Nov 20.
2018
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| 2 | AURKB, MAD1L1, MAD2L1
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| Regulation of AURORA B function by mitotic checkpoint protein MAD2.
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| Shandilya J, Medler KF, Roberts SG.
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| Cell Cycle 15(16):2196-2201. Epub 2016 Jun 24.
2016
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| 3 | BRSK2, KRTCAP3, MAD1L1
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| Epigenetic Variability across Human Populations: A Focus on DNA Methylation Profiles of the KRTCAP3, MAD1L1 and BRSK2 2016 PMID:
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| Giuliani C, Sazzini M, Bacalini MG, Pirazzini C, Marasco E, Fontanesi E, Franceschi C, Luiselli D, Garagnani P.
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| Genes. Genome Biol Evol. Sep 19;8(9):2760-73. doi: 10.1093/gbe/evw186. 2016
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| 4 | MAD1L1
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| Telomere length, c-myc and mad-1 expression could represent prognosis markers of myelodysplastic syndrome.
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| Poloni A, Serrani F, Berardinelli E, Maurizi G, Mariani M, Costantini B, Trappolini S, Mancini S, Olivieri A, Leoni P.
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| Leuk Res 37(11):1538-44. doi: 10.1016/j.leukres.2013.07.022. Epub 2013 Oct 3.
2013
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| 5 | MAD1L1, MAD2L1, TPR
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| Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis.
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| Schweizer N, Ferrás C, Kern DM, Logarinho E, Cheeseman IM, Maiato H.
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| J Cell Biol 203(6):883-93.
2013
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| 6 | CNOT3, MAD1L1
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| Involvement of CNOT3 in mitotic progression through inhibition of MAD1 expression.
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| Takahashi A, Kikuguchi C, Morita M, Shimodaira T, Tokai-Nishizumi N, Yokoyama K, Ohsugi M, Suzuki T, Yamamoto T.
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| Biochem Biophys Res Commun 419(2):268-73. doi: 10.1016/j.bbrc.2012.02.007. Epub 2012 Feb 10.
2012
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| 7 | IK, MAD1L1
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| RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint.
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| Yeh PC, Yeh CC, Chen YC, Juang YL.
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| J Biol Chem 287(15):11704-16. doi: 10.1074/jbc.M111.299131. Epub 2012 Feb 18.
2012
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| 8 | MAD1L1
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| Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons.
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| Ryan SD, Britigan EM, Zasadil LM, Witte K, Audhya A, Roopra A, Weaver BA.
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| Proc Natl Acad Sci U S A 109(33):E2205-14. doi: 10.1073/pnas.1201911109. Epub 2012 Jul 9.
2012
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| 9 | MAD1L1
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| Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting.
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| Kim S, Sun H, Tomchick DR, Yu H, Luo X.
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| Proc Natl Acad Sci U S A 109(17):6549-54. doi: 10.1073/pnas.1118210109. Epub 2012 Apr 9.
2012
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| 10 | MAD1L1
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| The spindle checkpoint protein MAD1 regulates the expression of E-cadherin and prevents cell migration.
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| Chen Y, Yeh PC, Huang JC, Yeh CC, Juang YL.
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| Oncol Rep 27(2):487-91. doi: 10.3892/or.2011.1519. Epub 2011 Oct 24.
2012
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| 11 | MAD1L1, NUP107
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| Dissecting the NUP107 complex: multiple components and even more functions.
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| González-Aguilera C, Askjaer P.
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| Nucleus 3(4):340-8. Epub 2012 Jun 20. Review.
2012
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| 12 | MAD1L1, MAD2L1
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| Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation.
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| Maldonado M, Kapoor TM.
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| Nat Cell Biol 13(4):475-82. Epub 2011 Mar 13. Erratum in: Nat Cell Biol. 2011 May;13(5):633.
2011
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| 13 | MAD1L1, MAD2L1
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| Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer.
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| Guo Y, Zhang X, Yang M, Miao X, Shi Y, Yao J, Tan W, Sun T, Zhao D, Yu D, Liu J, Lin D.
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| J Med Genet 47(9):616-22. Epub 2010 Jun 1.PMID: 20516147 2010
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| 14 | MAD1L1, NUP153
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| The nucleoporin Nup153 affects spindle checkpoint activity due to an association with Mad1.
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| Lussi YC, Shumaker DK, Shimi T, Fahrenkrog B.
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| Nucleus 1(1):71-84. doi: 10.4161/nucl.1.1.10244.
2010
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| 15 | BUB1B, DYNC1LI1, MAD1L1, MAD2L1, ZW10
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| Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.
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| Sivaram MV, Wadzinski TL, Redick SD, Manna T, Doxsey SJ.
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| EMBO J 28(7):902-14. Epub 2009 Feb 19. 2009
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| 16 | MAD1L1, MAD2L1, PLK1
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| Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1).
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| Chi YH, Haller K, Ward MD, Semmes OJ, Li Y, Jeang KT.
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| J Biol Chem 283(51):35834-44. Epub 2008 Oct 15.
2008
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| 17 | MAD1L1, MAD2L1
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| Insights into mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric mad2 dimer.
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| Yang M, Li B, Liu CJ, Tomchick DR, Machius M, Rizo J, Yu H, Luo X.
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| PLoS Biol 6(3):e50.
2008
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| 18 | PRPF4, MAD1L1, MAD2L1
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| PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores.
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| Montembault E, Dutertre S, Prigent C, Giet R.
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| J Cell Biol 179(4):601-9. Epub 2007 Nov 12. 2007
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| 19 | MAD1L1, MNT, MXI1
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| Expression and mutation analysis of genes that encode the Myc antagonists Mad1, Mxi1 and Rox in acute leukaemia.
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| Guo XL, Pan L, Zhang XJ, Suo XH, Niu ZY, Zhang JY, Wang F, Dong ZR, Da W, Ohno R.
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| Leuk Lymphoma 48(6):1200-7.
2007
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| 20 | MAD1L1
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| Gain of a region on 7p22.3, containing MAD1L1, is the most frequent event in small-cell lung cancer cell lines.
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| Coe BP, Lee EH, Chi B, Girard L, Minna JD, Gazdar AF, Lam S, MacAulay C, Lam WL.
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| Genes Chromosomes Cancer 45(1):11-9. 2006
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| 21 | MAD1L1, MAD2L1, BUB1B
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| The roles of MAD1, MAD2 and MAD3 in meiotic progression and the segregation of nonexchange chromosomes.
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| Cheslock PS, Kemp BJ, Boumil RM, Dawson DS.
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| Nat Genet 37(7):756-60. Epub 2005 Jun 12. 2005
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| 22 | FRK, GEMIN2, MAD1L1, TERT
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| Multiple tumor suppressor pathways negatively regulate telomerase.
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| Lin SY, Elledge SJ.
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| Cell 113(7):881-9. 2003
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| 23 | MAD1L1
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| Expression of mitotic spindle checkpoint protein hsMAD1 correlates with cellular proliferation and is activated by a gain-of-function p53 mutant.
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| Iwanaga Y, Jeang KT.
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| Cancer Res 62(9):2618-24. 2002
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| 24 | MAD1L1, MAD2L1
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| Characterization of regions in hsMAD1 needed for binding hsMAD2. A polymorphic change in an hsMAD1 leucine zipper affects MAD1-MAD2 interaction and spindle checkpoint function.
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| Iwanaga Y, Kasai T, Kibler K, Jeang KT.
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| J Biol Chem 277(34):31005-13. Epub 2002 May 31. 2002
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| 25 | MAD1L1
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| Mutations in the mitotic check point gene, MAD1L1, in human cancers.
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| Tsukasaki K, Miller CW, Greenspun E, Eshaghian S, Kawabata H, Fujimoto T, Tomonaga M, Sawyers C, Said JW, Koeffler HP.
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| Oncogene 20(25):3301-5. 2001
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| 26 | MAD1L1
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| Clinical implication of altered expression of Mad1 protein in human breast carcinoma.
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| Han S, Park K, Kim HY, Lee MS, Kim HJ, Kim YD, Yuh YJ, Kim SR, Suh HS.
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| Cancer 88(7):1623-32. 2000
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| 27 | MAD1L1, MAD2L1
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| Mitotic checkpoint locus MAD1L1 maps to human chromosome 7p22 and mouse chromosome 5.
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| Jin DY, et al.
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| Genomics 55(3):363-4. 1999
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| 28 | BUB1, BUB1B, BUB3, CDC20, MAD1L1, MAD2L1, MAD2L2, TTK
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| Characterization of MAD2B and other mitotic spindle checkpoint genes.
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| Cahill DP, et al.
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| Genomics 58(2):181-7. 1999
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| 29 | MAD1L1
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| Search for in vivo somatic mutations in the mitotic checkpoint gene, hMAD1, in human lung cancers.
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| Nomoto S, Haruki N, Takahashi T, Masuda A, Koshikawa T, Takahashi T, Fujii Y, Osada H, Takahashi T.
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| Oncogene 18(50):7180-3. 1999
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| 30 | CDC20, CDC27, MAD1L1
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| Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
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| Kallio M, et al.
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| J Cell Biol 141(6):1393-406. 1998
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| 31 | APC, CDC20, MAD1L1
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| The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.
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| Fang G, Yu H, Kirschner MW.
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| Genes Dev. 12(12):1871-83. 1998
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