1 | LXN
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| Latexin deficiency attenuates adipocyte differentiation and protects mice against obesity and metabolic disorders induced by high-fat diet.
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| Kan S, Li R, Tan Y, Yang F, Xu S, Wang L, Zhang L, Sun X, Chen X, Yang Y, Shu W, Wan H, Chen ZF, Liang H, Chen M.
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| Cell Death Dis. Feb 24;13(2):175. doi: 10.1038/s41419-022-04636-9. 2022
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2 | FLNA, LXN
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| LXN deficiency regulates cytoskeleton remodelling by promoting proteolytic cleavage of Filamin A in vascular endothelial cells
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| He G, Kan S, Xu S, Sun X, Li R, Shu W, Chen M.
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| J Cell Mol Med. Jul;25(14):6815-6827. doi: 10.1111/jcmm.16685. Epub 2021 Jun 3. 2021
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3 | LXN
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| The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy
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| Seed RI, Taurozzi AJ, Wilcock DJ, Nappo G, Erb HHH, Read ML, Gurney M, Archer LK, Ito S, Rumsby MG, Petrie JL, Clayton A, Maitland NJ, Collins AT.
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| Sci Rep. Mar 26;9(1):5120. doi: 10.1038/s41598-019-41379-8. 2019
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4 | LXN
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| Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice.
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| Liu Y, Zhang C, Li Z, Wang C, Jia J, Gao T, Hildebrandt G, Zhou D, Bondada S, Ji P, St Clair D, Liu J, Zhan C, Geiger H, Wang S, Liang Y.
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| Stem Cell Reports. Apr 11;8(4):991-1004. doi: 10.1016/j.stemcr.2017.02.009. Epub 2017 Mar 16 2017
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5 | LXN, PROM1
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| Latexin exhibits tumor-suppressor potential in pancreatic ductal adenocarcinoma.
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| Xue Z, Zhou Y, Wang C, Zheng J, Zhang P, Zhou L, Wu L, Shan Y, Ye M, He Y, Cai Z.
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| Oncol Rep. Jan;35(1):50-8. doi: 10.3892/or.2015.4353. Epub 2015 Oct 27. 2015
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6 | LXN
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| Latexin exhibits tumor suppressor potential in hepatocellular carcinoma.
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| Ni QF, Tian Y, Kong LL, Lu YT, Ding WZ, Kong LB.
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| Oncol Rep. Mar;31(3):1364-72. doi: 10.3892/or.2014.2966. Epub 2014 Jan 8. 2014
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7 | LXN, RARRES1
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| Retinoic acid represses invasion and stem cell phenotype by induction of the metastasis suppressors RARRES1 and LXN. 2013 PMID:
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| Oldridge EE, Walker HF, Stower MJ, Simms MS, Mann VM, Collins AT, Pellacani D, Maitland NJ.
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| Oncogenesis Apr 15;2(4):e45. doi: 10.1038/oncsis.2013.6. 2013
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8 | LXN
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| Latexin regulates the abundance of multiple cellular proteins in hematopoietic stem cells
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| Mitsunaga K, Kikuchi J, Wada T, Furukawa Y.
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| J Cell Physiol. Mar;227(3):1138-47. doi: 10.1002/jcp.22834. 2012
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9 | BMP2, LXN
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| Latexin is involved in bone morphogenetic protein-2-induced chondrocyte differentiation.
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| Kadouchi I, Sakamoto K, Tangjiao L, Murakami T, Kobayashi E, Hoshino Y, Yamaguchi A.
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| Biochem Biophys Res Commun 378(3):600-4. Epub 2008 Dec 4.
2009
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10 | LXN
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| Latexin is a newly discovered regulator of hematopoietic stem cells.
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| de Haan G.
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| Nat Genet 39(2):141-2. 2007
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11 | LXN
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| The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice.
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| Liang Y, Jansen M, Aronow B, Geiger H, Van Zant G.
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| Nat Genet 39(2):178-88. Epub 2007 Jan 14. 2007
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12 | CPA4, LXN
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| Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin.
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| Pallares I, Bonet R, Garcia-Castellanos R, Ventura S, Aviles FX, Vendrell J, Gomis-Ruth FX.
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| Proc Natl Acad Sci U S A 102(11):3978-83. Epub 2005 Feb 28. 2005
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13 | LXN
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| Cloning, tissue expression pattern and genomic organization of latexin, a human homologue of rat carboxypeptidase A inhibitor.
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| Liu Q, Yu L, Gao J, Fu Q, Zhang J, Zhang P, Chen J, Zhao S.
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| Mol Biol Rep 27(4):241-6. 2000
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14 | LXN
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| Genomic organization and regulatory elements of the rat latexin gene, which is expressed in a cell type-specific manner in both central and peripheral nervous systems.
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| Miyasaka N, Hatanaka Y, Jin M, Arimatsu Y.
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| Brain Res Mol Brain Res 69(1):62-72. 1999
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