1 | CCL2, LPA, OLR1
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| MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma.
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| Wiesner P, Tafelmeier M, Chittka D, Choi SH, Zhang L, Byun YS, Almazan F, Yang X, Iqbal N, Chowdhury P, Maisel A, Witztum JL, Handel TM, Tsimikas S, Miller YI.
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| J Lipid Res 54(7):1877-83. doi: 10.1194/jlr.M036343. Epub 2013 May 10.
2013
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2 | LPA, LPAL2, SLC22A3
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| Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
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| Trégouët DA, König IR, Erdmann J, Munteanu A, Braund PS, Hall AS, Grosshennig A, Linsel-Nitschke P, Perret C, DeSuremain M, Meitinger T, Wright BJ, Preuss M, Balmforth AJ, Ball SG, Meisinger C, Germain C, Evans A, Arveiler D, Luc G, Ruidavets JB, Morrison C, van der Harst P, Schreiber S, Neureuther K, Schäfer A, Bugert P, El Mokhtari NE, Schrezenmeir J, Stark K, Rubin D, Wichmann HE, Hengstenberg C, Ouwehand W; Wellcome Trust Case Control Consortium; Cardiogenics Consortium, Ziegler A, Tiret L, Thompson JR, Cambien F, Schunkert H, Samani NJ.
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| Nat Genet 41(3):283-5. Epub 2009 Feb 8.
2009
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3 | LPA
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| The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease.
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| Catalano M, Cortelazzo A, Yilmaz Y, Perilli E, Carzaniga G, Emanuele E.
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| Clin Chim Acta 387(1-2):109-12. Epub 2007 Sep 29. 2008
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4 | LPA
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| Secreted human apolipoprotein(a) kringle IV-10 and kringle V inhibit angiogenesis and xenografted tumor growth.
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| Shen L, Zhu X, Wang Y, Zeng W, Wu G, Xue H, Chen B.
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| Biol Chem 389(2):135-41. 2008
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5 | LPA, LPAR1, LPAR2, LPAR3, LPAR6
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| G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.
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| Pasternack SM, von KŸgelgen I, Aboud KA, Lee YA, RŸschendorf F, Voss K, Hillmer AM, Molderings GJ, Franz T, Ramirez A, NŸrnberg P, Nšthen MM, Betz RC.
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| Nat Genet 40(3):329-34. Epub 2008 Feb 24. 2008
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6 | LPA
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| A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease.
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| Luke MM, Kane JP, Liu DM, Rowland CM, Shiffman D, Cassano J, Catanese JJ, Pullinger CR, Leong DU, Arellano AR, Tong CH, Movsesyan I, Naya-Vigne J, Noordhof C, Feric NT, Malloy MJ, Topol EJ, Koschinsky ML, Devlin JJ, Ellis SG.
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| Arterioscler Thromb Vasc Biol 27(9):2030-6. Epub 2007 Jun 14. 2007
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7 | LPA
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| The apolipoprotein(a) component of lipoprotein(a) mediates binding to laminin: contribution to selective retention of lipoprotein(a) in atherosclerotic lesions.
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| D'Angelo A, Geroldi D, Hancock MA, Valtulina V, Cornaglia AI, Spencer CA, Emanuele E, Calligaro A, Koschinsky ML, Speziale P, Visai L.
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| Biochim Biophys Acta 1687(1-3):1-10. 2005
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8 | LPA
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| Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6 to 10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians.
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| Ogorelkova M, Kraft HG, Ehnholm C, Utermann G.
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| Hum Mol Genet 10(8):815-24. 2001
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9 | LPA
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| Counting the repetitive kringle-IV repeats in the gene encoding human apolipoprotein(a) by fibre-FISH.
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| Erdel M, et al.
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| Nat Genet 21(4):357-8. No abstract available 1999
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10 | ADRA2A, ADRB1, AGTR1, CAFG, CD36, CETP, CSF1, CSF2, CYP11B2, ECE1, EDN1, EDNRA, EDNRB, EGR1, F2R, FGA, FGB, FHBL1, HGF, ICAM1, IGF1, IL1A, IL6, LPA, MGP, MSR1, MTTP, NOS2, NOS3, PDGFA, PDGFRA, SELP, TGFB1, TNF, VCAM1, VDR
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| Sequence diversity in 36 candidate genes for cardiovascular disorders.
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| Cambien F, Poirier O, Nicaud V, Herrmann SM, Mallet C, Ricard S, Behague I, Hallet V, Blanc H, Loukaci V, Thillet J, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L.
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| Am J Hum Genet 65(1):183-91. 1999
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11 | LPA
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| Molecular basis of congenital lp(a) deficiency: a frequent apo(a) 'null' mutation in caucasians.
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| Ogorelkova M, Gruber A, Utermann G.
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| Hum Mol Genet 8(11):2087-96. 1999
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12 | LPA
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| Genomic structure and organization of kringles type 3 to 10 of the apolipoprotein(a) gene in 6q26-27.
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| Mihalich A, Magnaghi P, Sessa L, Trubia M, Acquati F, Taramelli R.
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| Gene 196(1-2):1-8. 1997
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13 | LPA
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| Apolipoprotein(a) kringle 4-containing fragments in human urine. Relationship to plasma levels of lipoprotein(a).
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| Mooser V, et al.
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| J Clin Invest 97 : 858-864. 1996
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14 | LPA
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| A pentanucleotide repeat polymorphism in the 5' control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians.
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| Trommsdorff M, et al.
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| J Clin Invest 96 : 150-157. 1995
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15 | LPA
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| Sequence microheterogeneity in apolipoprotein(a) gene repeats and the relationship to plasma Lp(a) levels.
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| Mancini FP, et al.
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| Hum Mol Genet 4 : 1535-1542. 1995
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16 | LPA, LPAL1, LPAL2, TRDP
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| Molecular characterisation of the human apo(a)-plasminogen gene family clustered on the telomeric region of chromosome 6 (6q26-27).
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| Magnaghi P, et al.
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| Hum Mol Genet 3 : 437-442. 1994
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17 | LPA
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| Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis.
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| Lackner C, et al.
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| J Clin Invest 87 : 2153-2161. 1991
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18 | LPA
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| Restriction site polymorphism at the LPA (Lp(a) apolipoprotein; apolipoprotein (a)) locus.
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| Berg K, et al.
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| Clin Genet 37 : 473-480. 1990
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19 | LPA
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| The gene for the Lp(a)-specific glycoprotein is closely linked to the gene for plasminogen on chromosome 6.
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| Lindahl G, Gersdorf E, Menzel HJ, Duba C, Cleve H, Humphries S, Utermann G.
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| Hum Genet 81 : 149-152. 1989
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20 | LPA
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| Impact of medical genetics on research and practices in the area of cardiovascular disease.
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| Berg K.
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| Clin Genet 36 : 299-312. 1989
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21 | LPA, ESD
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| No evidence for linkage between lipoprotein(a) (LPA) and esterase D (ESD).
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| Greger V, Gersdorf E, Utermann G, Horsthemke B.
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| Cytogenet Cell Genet 48 : 248-249. 1988
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22 | LPA
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| Linkage between the loci for the Lp(a) lipoprotein (LP) and plasminogen (PLG).
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| Weitkamp LR, et al.
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| Hum Genet 79 : 80-82. 1988
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23 | LPA
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| The apolipoprotein(a) gene resides on human chromosome 6q26-q27, in close proximity to the homologous gene for plasminogen.
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| Frank SL, et al.
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| Hum Genet 79 : 352-356. 1988
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24 | LPA
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| cDNA sequence of human apolipoprotein(a) is homologous to plasminogen.
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| McLean JW, et al.
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| Nature 330 : 132-137. 1987
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25 | LPA
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| cDNA sequence of human apolipoprotein (a) is homologous to plasminogen.
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| McLean JW, et al.
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| Nature 330 : 132-137. 1981
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