Citations for
1LOXL2, NOTCH1
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.
Martin A, Salvador F, Moreno-Bueno G, Floristán A, Ruiz-Herguido C, Cuevas EP, Morales S, Santos V, Csiszar K, Dubus P, Haigh JJ, Bigas A, Portillo F, Cano A.
EMBO J 34(8):1090-109. doi: 10.15252/embj.201489975. Epub 2015 Mar 10. 2015
2LOXL2
Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 Δe13, in esophageal squamous cell carcinoma.
Lv GQ, Zou HY, Liao LD, Cao HH, Zeng FM, Wu BL, Xie JJ, Fang WK, Xu LY, Li EM.
Biochem Cell Biol 92(5):379-89. doi: 10.1139/bcb-2014-0046. Epub 2014 Aug 5. 2014
3LOXL2
Human lysyl oxidase-like 2.
Moon HJ, Finney J, Ronnebaum T, Mure M.
Bioorg Chem 57:231-41. doi: 10.1016/j.bioorg.2014.07.003. Epub 2014 Aug 1. 2014
4LOX, LOXL2
A new role for LOX and LOXL2 proteins in transcription regulation.
Iturbide A, García de Herreros A, Peiró S.
FEBS J EBS J. 2014 Aug 8. doi: 10.1111/febs.12961. [Epub ahead of print] 2014
5LOXL2, MARCKSL1
Lysyl oxidase-like 2 (LOXL2) controls tumor-associated cell proliferation through the interaction with MARCKSL1.
Kim BR, Dong SM, Seo SH, Lee JH, Lee JM, Lee SH, Rho SB.
Cell Signal 26(9):1765-73. doi: 10.1016/j.cellsig.2014.05.010. Epub 2014 May 24. 2014
6LOXL2, SNAI1
Regulation of heterochromatin transcription by Snail1/LOXL2 during epithelial-to-mesenchymal transition.
Millanes-Romero A, Herranz N, Perrera V, Iturbide A, Loubat-Casanovas J, Gil J, Jenuwein T, García de Herreros A, Peiró S.
Mol Cell 52(5):746-57. doi: 10.1016/j.molcel.2013.10.015. Epub 2013 Nov 14. 2013
7LOXL2
Tumor-secreted LOXL2 activates fibroblasts through FAK signaling.
Barker HE, Bird D, Lang G, Erler JT.
Mol Cancer Res 11(11):1425-36. doi: 10.1158/1541-7786.MCR-13-0033-T. Epub 2013 Sep 5. 2013
8ERBB2, LOXL2
LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.
Chang J, Nicolau MM, Cox TR, Wetterskog D, Martens JW, Barker HE, Erler JT.
Breast Cancer Res 15(4):R67. 2013
9LOXL2
Post-translational modifications of recombinant human lysyl oxidase-like 2 (rhLOXL2) secreted from Drosophila S2 cells.
Xu L, Go EP, Finney J, Moon H, Lantz M, Rebecchi K, Desaire H, Mure M.
J Biol Chem 288(8):5357-63. doi: 10.1074/jbc.C112.421768. Epub 2013 Jan 14. 2013
10LOX, LOXL2
The potential for targeting extracellular LOX proteins in human malignancy.
Mayorca-Guiliani A, Erler JT.
Onco Targets Ther 6:1729-35. doi: 10.2147/OTT.S38110. Review. 2013
11LOXL2
LOXL2 in epithelial cell plasticity and tumor progression.
Cano A, Santamaría PG, Moreno-Bueno G.
Future Oncol 8(9):1095-108. doi: 10.2217/fon.12.105. Review. 2012
12LOXL2
Lysyl oxidase-like 2 deaminates lysine 4 in histone H3.
Herranz N, Dave N, Millanes-Romero A, Morey L, Díaz VM, Lórenz-Fonfría V, Gutierrez-Gallego R, Jerónimo C, Di Croce L, García de Herreros A, Peiró S.
Mol Cell 46(3):369-76. doi: 10.1016/j.molcel.2012.03.002. Epub 2012 Apr 5. 2012
13LOXL2
The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation.
Lugassy J, Zaffryar-Eilot S, Soueid S, Mordoviz A, Smith V, Kessler O, Neufeld G.
J Biol Chem 287(5):3541-9. doi: 10.1074/jbc.M111.261016. Epub 2011 Dec 8. 2012
14LOXL2
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.
Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, Evans HR, Gartland A, Erler JT.
Cancer Res 71(5):1561-72. Epub 2011 Jan 13. 2011
15LOXL2
Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation.
Iftikhar M, Hurtado P, Bais MV, Wigner N, Stephens DN, Gerstenfeld LC, Trackman PC.
J Biol Chem 286(2):909-18. Epub 2010 Nov 11. 2011
16LOXL2, RAMP3
Receptor activity modifying protein-3 mediates the protumorigenic activity of lysyl oxidase-like protein-2.
Brekhman V, Lugassie J, Zaffryar-Eilot S, Sabo E, Kessler O, Smith V, Golding H, Neufeld G.
FASEB J 25(1):55-65. Epub 2010 Aug 27. 2011
17LOXL2
The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin.
Kim YM, Kim EC, Kim Y.
Mol Biol Rep 38(1):145-9. Epub 2010 Mar 21. 2011
18LOXL2
The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1.
Schietke R, Warnecke C, Wacker I, Schödel J, Mole DR, Campean V, Amann K, Goppelt-Struebe M, Behrens J, Eckardt KU, Wiesener MS.
J Biol Chem 285(9):6658-69. Epub 2009 Dec 21. 2010
19LOXL2
Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor.
Rodriguez HM, Vaysberg M, Mikels A, McCauley S, Velayo AC, Garcia C, Smith V.
J Biol Chem 285(27):20964-74. Epub 2010 May 3. 2010
20LOXL2
Functional analysis of LOXL2 in pancreatic carcinoma.
Rückert F, Joensson P, Saeger HD, Grützmann R, Pilarsky C.
Int J Colorectal Dis 25(3):303-11. Epub 2009 Dec 9. 2010
21LOXL2
Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway.
Peng L, Ran YL, Hu H, Yu L, Liu Q, Zhou Z, Sun YM, Sun LC, Pan J, Sun LX, Zhao P, Yang ZH.
Carcinogenesis 30(10):1660-9. Epub 2009 Jul 22. 2009
22LOXL2
Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas.
Peinado H, Moreno-Bueno G, Hardisson D, Pérez-Gómez E, Santos V, Mendiola M, de Diego JI, Nistal M, Quintanilla M, Portillo F, Cano A.
Cancer Res 68(12):4541-50. 2008
23LOXL2
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
Fong SF, Dietzsch E, Fong KS, Hollosi P, Asuncion L, He Q, Parker MI, Csiszar K.
Genes Chromosomes Cancer 46(7):644-55. 2007
24LOXL2
Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptibility gene to intracranial aneurysms.
Akagawa H, Narita A, Yamada H, Tajima A, Krischek B, Kasuya H, Hori T, Kubota M, Saeki N, Hata A, Mizutani T, Inoue I.
Hum Genet 121(3-4):377-87. Epub 2007 Feb 8. 2007
25LOXL1, LOXL2, LOXL3
Lysyl oxidases: a novel multifunctional amine oxidase family.
Csiszar K.
Prog Nucleic Acid Res Mol Biol 70:1-32. Review. 2001
26LOXL2
The LOXL2 gene encodes a new lysyl oxidase-like protein and is expressed at high levels in reproductive tissues.
Jourdan-Le Saux C, et al.
J Biol Chem 274(18):12939-44. 1999
27LOXL2
The human lysyl oxidase-related gene (LOXL2) maps between markers D8S280 and D8S278 on chromosome 8p21.2-p21.3.
Jourdan-Le Saux C, et al.
Genomics 51 : 305-307. 1998