| 1 | LDB1, LMO4, SSBP2, SSBP3
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| LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).
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| Simonik EA, Cai Y, Kimmelshue KN, Brantley-Sieders DM, Loomans HA, Andl CD, Westlake GM, Youngblood VM, Chen J, Yarbrough WG, Brown BT, Nagarajan L, Brandt SJ.
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| PLoS One 11(10):e0164804. doi: 10.1371/journal.pone.0164804. eCollection 2016.
2016
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| 2 | FGFR2, LDB1, LMO4
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| The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.
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| Salmans ML, Yu Z, Watanabe K, Cam E, Sun P, Smyth P, Dai X, Andersen B.
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| PLoS Genet 10(7):e1004520. doi: 10.1371/journal.pgen.1004520. eCollection 2014 Jul.
2014
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| 3 | LMO4, RBBP8
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| Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8.
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| Stokes PH, Liew CW, Kwan AH, Foo P, Barker HE, Djamirze A, O'Reilly V, Visvader JE, Mackay JP, Matthews JM.
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| J Mol Biol 425(7):1101-10. doi: 10.1016/j.jmb.2013.01.017. Epub 2013 Jan 23.
2013
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| 4 | LMO4, NEUROG2
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| LMO4 functions as a co-activator of neurogenin 2 in the developing cortex.
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| Asprer JS, Lee B, Wu CS, Vadakkan T, Dickinson ME, Lu HC, Lee SK.
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| Development 138(13):2823-32.
2011
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| 5 | LMO4
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| Loss of LMO4 in the retina leads to reduction of GABAergic amacrine cells and functional deficits.
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| Duquette PM, Zhou X, Yap NL, MacLaren EJ, Lu JJ, Wallace VA, Chen HH.
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| PLoS One 5(10):e13232.
2010
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| 6 | CITED2, LMO4
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| A novel role for transcription factor Lmo4 in thymus development through genetic interaction with Cited2.
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| Michell AC, Bragança J, Broadbent C, Joyce B, Franklyn A, Schneider JE, Bhattacharya S, Bamforth SD.
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| Dev Dyn 239(7):1988-94.
2010
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| 7 | LMO4
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| Repression of Lim only protein 4-activated transcription inhibits proliferation and induces apoptosis of normal mammary epithelial cells and breast cancer cells.
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| Tian Y, Wang N, Lu Z.
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| Clin Exp Metastasis 27(7):455-63. Epub 2010 Jun 6.
2010
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| 8 | LMO4
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| LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression.
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| Montañez-Wiscovich ME, Seachrist DD, Landis MD, Visvader J, Andersen B, Keri RA.
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| Oncogene 28(41):3608-18. Epub 2009 Aug 3.
2009
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| 9 | GRHL3, LMO4
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| Grhl3 and Lmo4 play coordinate roles in epidermal migration.
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| Hislop NR, Caddy J, Ting SB, Auden A, Vasudevan S, King SL, Lindeman GJ, Visvader JE, Cunningham JM, Jane SM.
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| Dev Biol 321(1):263-72. Epub 2008 Jun 26.
2008
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| 10 | LMO4
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| LIM only 4 is overexpressed in late stage pancreas cancer.
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| Yu J, Ohuchida K, Nakata K, Mizumoto K, Cui L, Fujita H, Yamaguchi H, Egami T, Kitada H, Tanaka M.
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| Mol Cancer 7:93.
2008
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| 11 | LMO4
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| Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer.
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| Sum EY, Segara D, Duscio B, Bath ML, Field AS, Sutherland RL, Lindeman GJ, Visvader JE.
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| Proc Natl Acad Sci U S A 102(21):7659-64. Epub 2005 May 16. 2005
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| 12 | LMO4
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| Negative regulation of estrogen receptor alpha transactivation functions by LIM domain only 4 protein.
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| Singh RR, Barnes CJ, Talukder AH, Fuqua SA, Kumar R.
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| Cancer Res 65(22):10594-601.
2005
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| 13 | DEAF1, LMO4
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| Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1.
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| Hahm K, Sum EY, Fujiwara Y, Lindeman GJ, Visvader JE, Orkin SH.
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| Mol Cell Biol 24(5):2074-82.
2004
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| 14 | LMO4, LDB1
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| The LIM-only protein, LMO4, and the LIM domain-binding protein, LDB1, expression in squamous cell carcinomas of the oral cavity.
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| Mizunuma H, Miyazawa J, Sanada K, Imai K.
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| Br J Cancer 88(10):1543-8. 2003
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| 15 | LMO4, LMO2, NHLH1, LMO4, CSRP3
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| The LIM-only protein LMO4 modulates the transcriptional activity of HEN1.
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| Manetopoulos C, Hansson A, Karlsson J, Jonsson JI, Axelson H.
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| Biochem Biophys Res Commun 307(4):891-9. 2003
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| 16 | BRCA1, LMO4, RBBP8
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| The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity.
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| Sum EY, Peng B, Yu X, Chen J, Byrne J, Lindeman GJ, Visvader JE.
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| J Biol Chem 277(10):7849-56. 2002
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| 17 | LMO4
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| The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer.
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| Visvader JE, Venter D, Hahm K, Santamaria M, Sum EY, O'Reilly L, White D, Williams R, Armes J, Lindeman GJ.
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| Proc Natl Acad Sci U S A 98(25):14452-7. 2001
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| 18 | LMO4
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| Characterization of the Lmo4 gene encoding a LIM-only protein: genomic organization and comparative chromosomal mapping.
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| Tse E, Grutz G, Garner AA, Ramsey Y, Carter NP, Copeland N, Gilbert DJ, Jenkins NA, Agulnick A, Forster A, Rabbitts TH.
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| Mamm Genome 10(11):1089-94. 1999
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