Citations for
1LIN28A, MSI2
Musashi 2 contributes to the stemness and chemoresistance of liver cancer stem cells via LIN28A activation.
Fang T, Lv H, Wu F, Wang C, Li T, Lv G, Tang L, Guo L, Tang S, Cao D, Wu M, Yang W, Wang H.
Cancer Lett 384:50-59. doi: 10.1016/j.canlet.2016.10.007. Epub 2016 Oct 6. 2017
2LIN28A, LIN28B
LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency.
Zhang J, Ratanasirintrawoot S, Chandrasekaran S, Wu Z, Ficarro SB, Yu C, Ross CA, Cacchiarelli D, Xia Q, Seligson M, Shinoda G, Xie W, Cahan P, Wang L, Ng SC, Tintara S, Trapnell C, Onder T, Loh YH, Mikkelsen T, Sliz P, Teitell MA, Asara JM, Marto JA, Li H, Collins JJ, Daley GQ.
Cell Stem Cell 19(1):66-80. doi: 10.1016/j.stem.2016.05.009. Epub 2016 Jun 16. 2016
3LIN28A, NANOG, PCGF6, POU5F1, SOX2
Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity
Yang CS, Chang KY, Dang J, Rana TM.
Sci Rep. Jun 1;6:26899. doi: 10.1038/srep26899. 2016
4LIN28A, LIN28B
Lin28 promotes the proliferative capacity of neural progenitor cells in brain development.
Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF.
Development 142(9):1616-27. doi: 10.1242/dev.120543. 2015
5LIN28A, LIN28B
The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy.
Wang LD, Rao TN, Rowe RG, Nguyen PT, Sullivan JL, Pearson DS, Doulatov S, Wu L, Lindsley RC, Zhu H, DeAngelo DJ, Daley GQ, Wagers AJ.
Leukemia 29(6):1320-30. doi: 10.1038/leu.2015.19. Epub 2015 Feb 6. 2015
6LIN28A
Lin28a is dormant, functional, and dispensable during mouse oocyte-to-embryo transition.
Flemr M, Moravec M, Libova V, Sedlacek R, Svoboda P.
Biol Reprod 90(6):131. doi: 10.1095/biolreprod.114.118703. Epub 2014 May 14. 2014
7LARP7, LIN28A, TUT1
Primordial dwarfism gene maintains Lin28 expression to safeguard embryonic stem cells from premature differentiation.
Dai Q, Luan G, Deng L, Lei T, Kang H, Song X, Zhang Y, Xiao ZX, Li Q.
Cell Rep 7(3):735-46. doi: 10.1016/j.celrep.2014.03.053. Epub 2014 Apr 24. 2014
8LIN28A
Lin28 enhances tissue repair by reprogramming cellular metabolism.
Shyh-Chang N, Zhu H, Yvanka de Soysa T, Shinoda G, Seligson MT, Tsanov KM, Nguyen L, Asara JM, Cantley LC, Daley GQ.
Cell 155(4):778-92. doi: 10.1016/j.cell.2013.09.059. 2013
9LIN28A
Role of LIN28A in mouse and human trophoblast cell differentiation.
Seabrook JL, Cantlon JD, Cooney AJ, McWhorter EE, Fromme BA, Bouma GJ, Anthony RV, Winger QA.
Biol Reprod 89(4):95. doi: 10.1095/biolreprod.113.109868. Print 2013 Oct. 2013
10LIN28A, LIN28B
Lin28: primal regulator of growth and metabolism in stem cells.
Shyh-Chang N, Daley GQ.
Cell Stem Cell 12(4):395-406. doi: 10.1016/j.stem.2013.03.005. Review. 2013
11LIN28A
Lin28 promotes growth of prostate cancer cells and activates the androgen receptor.
Tummala R, Nadiminty N, Lou W, Zhu Y, Gandour-Edwards R, Chen HW, Evans CP, Gao AC.
Am J Pathol 183(1):288-95. doi: 10.1016/j.ajpath.2013.03.011. 2013
12BMP4, LIN28A
Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironment.
Ma W, Ma J, Xu J, Qiao C, Branscum A, Cardenas A, Baron AT, Schwartz P, Maihle NJ, Huang Y.
Cell Cycle 12(1):88-97. doi: 10.4161/cc.23028. Epub 2012 Dec 19. 2013
13DROSHA, LIN28A
Drosha mediates destabilization of Lin28 mRNA targets.
Qiao C, Ma J, Xu J, Xie M, Ma W, Huang Y.
Cell Cycle 11(19):3590-8. doi: 10.4161/cc.21871. Epub 2012 Aug 30. 2012
14LIN28A
Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development.
Vogt EJ, Meglicki M, Hartung KI, Borsuk E, Behr R.
Development 139(24):4514-23. doi: 10.1242/dev.083279. 2012
15LIN28A
LIN28A is a suppressor of ER-associated translation in embryonic stem cells.
Cho J, Chang H, Kwon SC, Kim B, Kim Y, Choe J, Ha M, Kim YK, Kim VN.
Cell 151(4):765-77. doi: 10.1016/j.cell.2012.10.019. Epub 2012 Oct 25. 2012
16LIN28A
Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer.
Li N, Zhong X, Lin X, Guo J, Zou L, Tanyi JL, Shao Z, Liang S, Wang LP, Hwang WT, Katsaros D, Montone K, Zhao X, Zhang L.
J Biol Chem 287(21):17386-97. doi: 10.1074/jbc.M111.321158. Epub 2012 Mar 30. 2012
17LIN28A
LIN28 is selectively expressed by primordial and pre-meiotic germ cells in the human fetal ovary.
Childs AJ, Kinnell HL, He J, Anderson RA.
Stem Cells Dev 21(13):2343-9. doi: 10.1089/scd.2011.0730. Epub 2012 Mar 6. 2012
18LIN28A, LIN28B
LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance.
Wilbert ML, Huelga SC, Kapeli K, Stark TJ, Liang TY, Chen SX, Yan BY, Nathanson JL, Hutt KR, Lovci MT, Kazan H, Vu AQ, Massirer KB, Morris Q, Hoon S, Yeo GW.
Mol Cell 48(2):195-206. doi: 10.1016/j.molcel.2012.08.004. Epub 2012 Sep 6. 2012
19LIN28A, LIN28B, MIRLET7A1
The Lin28/let-7 axis regulates glucose metabolism.
Zhu H, Shyh-Chang N, Segrč AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators, Altshuler D, Daley GQ.
Cell 147(1):81-94. 2011
20LIN28A, POU5F1
Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells.
Qiu C, Ma Y, Wang J, Peng S, Huang Y.
Nucleic Acids Res 38(4):1240-8. Epub 2009 Dec 4. 2010
21LIN28A
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies.
Zhu H, Shah S, Shyh-Chang N, Shinoda G, Einhorn WS, Viswanathan SR, Takeuchi A, Grasemann C, Rinn JL, Lopez MF, Hirschhorn JN, Palmert MR, Daley GQ.
Nat Genet 42(7):626-30. Epub 2010 May 30.PMID: 2051214 2010
22LIN28A
A role for Lin28 in primordial germ-cell development and germ-cell malignancy.
West JA, Viswanathan SR, Yabuuchi A, Cunniff K, Takeuchi A, Park IH, Sero JE, Zhu H, Perez-Atayde A, Frazier AL, Surani MA, Daley GQ.
Nature 460(7257):909-13. Epub 2009 Jul 5. 2009
23LIN28A, LIN28B
Lin28 promotes transformation and is associated with advanced human malignancies.
Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, O'Sullivan M, Lu J, Phillips LA, Lockhart VL, Shah SP, Tanwar PS, Mermel CH, Beroukhim R, Azam M, Teixeira J, Meyerson M, Hughes TP, Llovet JM, Radich J, Mullighan CG, Golub TR, Sorensen PH, Daley GQ.
Nat Genet 41(7):843-8. Epub 2009 May 31. 2009
24LIN28A
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA.
Heo I, Joo C, Cho J, Ha M, Han J, Kim VN.
Mol Cell 32(2):276-84. 2008
25LIN28A
Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules.
Balzer E, Moss EG.
RNA Biol 4(1):16-25. Epub 2007 Apr 30. 2007
26LIN28A
Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells.
Wu L, Belasco JG.
Mol Cell Biol 25(21):9198-208. 2005
27LIN28A
Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites.
Moss EG, Tang L.
Dev Biol 258(2):432-42. Erratum in: Dev Biol. 2003 Oct 15;262(2):361. 2003