1 | LIN28A, MSI2
|
| Musashi 2 contributes to the stemness and chemoresistance of liver cancer stem cells via LIN28A activation.
|
| Fang T, Lv H, Wu F, Wang C, Li T, Lv G, Tang L, Guo L, Tang S, Cao D, Wu M, Yang W, Wang H.
|
| Cancer Lett 384:50-59. doi: 10.1016/j.canlet.2016.10.007. Epub 2016 Oct 6.
2017
|
2 | LIN28A, LIN28B
|
| LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency.
|
| Zhang J, Ratanasirintrawoot S, Chandrasekaran S, Wu Z, Ficarro SB, Yu C, Ross CA, Cacchiarelli D, Xia Q, Seligson M, Shinoda G, Xie W, Cahan P, Wang L, Ng SC, Tintara S, Trapnell C, Onder T, Loh YH, Mikkelsen T, Sliz P, Teitell MA, Asara JM, Marto JA, Li H, Collins JJ, Daley GQ.
|
| Cell Stem Cell 19(1):66-80. doi: 10.1016/j.stem.2016.05.009. Epub 2016 Jun 16.
2016
|
3 | LIN28A, NANOG, PCGF6, POU5F1, SOX2
|
| Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity
|
| Yang CS, Chang KY, Dang J, Rana TM.
|
| Sci Rep. Jun 1;6:26899. doi: 10.1038/srep26899. 2016
|
4 | LIN28A, LIN28B
|
| Lin28 promotes the proliferative capacity of neural progenitor cells in brain development.
|
| Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF.
|
| Development 142(9):1616-27. doi: 10.1242/dev.120543.
2015
|
5 | LIN28A, LIN28B
|
| The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy.
|
| Wang LD, Rao TN, Rowe RG, Nguyen PT, Sullivan JL, Pearson DS, Doulatov S, Wu L, Lindsley RC, Zhu H, DeAngelo DJ, Daley GQ, Wagers AJ.
|
| Leukemia 29(6):1320-30. doi: 10.1038/leu.2015.19. Epub 2015 Feb 6.
2015
|
6 | LIN28A
|
| Lin28a is dormant, functional, and dispensable during mouse oocyte-to-embryo transition.
|
| Flemr M, Moravec M, Libova V, Sedlacek R, Svoboda P.
|
| Biol Reprod 90(6):131. doi: 10.1095/biolreprod.114.118703. Epub 2014 May 14.
2014
|
7 | LARP7, LIN28A, TUT1
|
| Primordial dwarfism gene maintains Lin28 expression to safeguard embryonic stem cells from premature differentiation.
|
| Dai Q, Luan G, Deng L, Lei T, Kang H, Song X, Zhang Y, Xiao ZX, Li Q.
|
| Cell Rep 7(3):735-46. doi: 10.1016/j.celrep.2014.03.053. Epub 2014 Apr 24.
2014
|
8 | LIN28A
|
| Lin28 enhances tissue repair by reprogramming cellular metabolism.
|
| Shyh-Chang N, Zhu H, Yvanka de Soysa T, Shinoda G, Seligson MT, Tsanov KM, Nguyen L, Asara JM, Cantley LC, Daley GQ.
|
| Cell 155(4):778-92. doi: 10.1016/j.cell.2013.09.059.
2013
|
9 | LIN28A
|
| Role of LIN28A in mouse and human trophoblast cell differentiation.
|
| Seabrook JL, Cantlon JD, Cooney AJ, McWhorter EE, Fromme BA, Bouma GJ, Anthony RV, Winger QA.
|
| Biol Reprod 89(4):95. doi: 10.1095/biolreprod.113.109868. Print 2013 Oct.
2013
|
10 | LIN28A, LIN28B
|
| Lin28: primal regulator of growth and metabolism in stem cells.
|
| Shyh-Chang N, Daley GQ.
|
| Cell Stem Cell 12(4):395-406. doi: 10.1016/j.stem.2013.03.005. Review.
2013
|
11 | LIN28A
|
| Lin28 promotes growth of prostate cancer cells and activates the androgen receptor.
|
| Tummala R, Nadiminty N, Lou W, Zhu Y, Gandour-Edwards R, Chen HW, Evans CP, Gao AC.
|
| Am J Pathol 183(1):288-95. doi: 10.1016/j.ajpath.2013.03.011.
2013
|
12 | BMP4, LIN28A
|
| Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironment.
|
| Ma W, Ma J, Xu J, Qiao C, Branscum A, Cardenas A, Baron AT, Schwartz P, Maihle NJ, Huang Y.
|
| Cell Cycle 12(1):88-97. doi: 10.4161/cc.23028. Epub 2012 Dec 19.
2013
|
13 | DROSHA, LIN28A
|
| Drosha mediates destabilization of Lin28 mRNA targets.
|
| Qiao C, Ma J, Xu J, Xie M, Ma W, Huang Y.
|
| Cell Cycle 11(19):3590-8. doi: 10.4161/cc.21871. Epub 2012 Aug 30.
2012
|
14 | LIN28A
|
| Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development.
|
| Vogt EJ, Meglicki M, Hartung KI, Borsuk E, Behr R.
|
| Development 139(24):4514-23. doi: 10.1242/dev.083279.
2012
|
15 | LIN28A
|
| LIN28A is a suppressor of ER-associated translation in embryonic stem cells.
|
| Cho J, Chang H, Kwon SC, Kim B, Kim Y, Choe J, Ha M, Kim YK, Kim VN.
|
| Cell 151(4):765-77. doi: 10.1016/j.cell.2012.10.019. Epub 2012 Oct 25.
2012
|
16 | LIN28A
|
| Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer.
|
| Li N, Zhong X, Lin X, Guo J, Zou L, Tanyi JL, Shao Z, Liang S, Wang LP, Hwang WT, Katsaros D, Montone K, Zhao X, Zhang L.
|
| J Biol Chem 287(21):17386-97. doi: 10.1074/jbc.M111.321158. Epub 2012 Mar 30.
2012
|
17 | LIN28A
|
| LIN28 is selectively expressed by primordial and pre-meiotic germ cells in the human fetal ovary.
|
| Childs AJ, Kinnell HL, He J, Anderson RA.
|
| Stem Cells Dev 21(13):2343-9. doi: 10.1089/scd.2011.0730. Epub 2012 Mar 6.
2012
|
18 | LIN28A, LIN28B
|
| LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance.
|
| Wilbert ML, Huelga SC, Kapeli K, Stark TJ, Liang TY, Chen SX, Yan BY, Nathanson JL, Hutt KR, Lovci MT, Kazan H, Vu AQ, Massirer KB, Morris Q, Hoon S, Yeo GW.
|
| Mol Cell 48(2):195-206. doi: 10.1016/j.molcel.2012.08.004. Epub 2012 Sep 6.
2012
|
19 | LIN28A, LIN28B, MIRLET7A1
|
| The Lin28/let-7 axis regulates glucose metabolism.
|
| Zhu H, Shyh-Chang N, Segrč AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators, Altshuler D, Daley GQ.
|
| Cell 147(1):81-94.
2011
|
20 | LIN28A, POU5F1
|
| Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells.
|
| Qiu C, Ma Y, Wang J, Peng S, Huang Y.
|
| Nucleic Acids Res 38(4):1240-8. Epub 2009 Dec 4. 2010
|
21 | LIN28A
|
| Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies.
|
| Zhu H, Shah S, Shyh-Chang N, Shinoda G, Einhorn WS, Viswanathan SR, Takeuchi A, Grasemann C, Rinn JL, Lopez MF, Hirschhorn JN, Palmert MR, Daley GQ.
|
| Nat Genet 42(7):626-30. Epub 2010 May 30.PMID: 2051214 2010
|
22 | LIN28A
|
| A role for Lin28 in primordial germ-cell development and germ-cell malignancy.
|
| West JA, Viswanathan SR, Yabuuchi A, Cunniff K, Takeuchi A, Park IH, Sero JE, Zhu H, Perez-Atayde A, Frazier AL, Surani MA, Daley GQ.
|
| Nature 460(7257):909-13. Epub 2009 Jul 5. 2009
|
23 | LIN28A, LIN28B
|
| Lin28 promotes transformation and is associated with advanced human malignancies.
|
| Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, O'Sullivan M, Lu J, Phillips LA, Lockhart VL, Shah SP, Tanwar PS, Mermel CH, Beroukhim R, Azam M, Teixeira J, Meyerson M, Hughes TP, Llovet JM, Radich J, Mullighan CG, Golub TR, Sorensen PH, Daley GQ.
|
| Nat Genet 41(7):843-8. Epub 2009 May 31. 2009
|
24 | LIN28A
|
| Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA.
|
| Heo I, Joo C, Cho J, Ha M, Han J, Kim VN.
|
| Mol Cell 32(2):276-84. 2008
|
25 | LIN28A
|
| Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules.
|
| Balzer E, Moss EG.
|
| RNA Biol 4(1):16-25. Epub 2007 Apr 30. 2007
|
26 | LIN28A
|
| Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells.
|
| Wu L, Belasco JG.
|
| Mol Cell Biol 25(21):9198-208. 2005
|
27 | LIN28A
|
| Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites.
|
| Moss EG, Tang L.
|
| Dev Biol 258(2):432-42. Erratum in: Dev Biol. 2003 Oct 15;262(2):361. 2003
|