| 1 | CDKN1C, LHX6, LHX8 |
| Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2 | |
| Cesario JM, Landin Malt A, Deacon LJ, Sandberg M, Vogt D, Tang Z, Zhao Y, Brown S, Rubenstein JL, Jeong J | |
| Hum Mol Genet. Sep 1;24(17):5024-39. doi: 10.1093/hmg/ddv223. Epub 2015 Jun 12 2015 | |
| 2 | GAD1, LHX6 |
| Cortical Inhibitory Neuron Disturbances in Schizophrenia: Role of the Ontogenetic Transcription Factor Lhx6. | |
| Volk DW, Edelson JR, Lewis DA. | |
| Schizophr Bull chizophr Bull. 2014 May 17. pii: sbu068. [Epub ahead of print] 2014 | |
| 3 | ACKR3, ARX, LHX6 |
| Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position. | |
| Vogt D, Hunt RF, Mandal S, Sandberg M, Silberberg SN, Nagasawa T, Yang Z, Baraban SC, Rubenstein JL. | |
| Neuron 82(2):350-64. doi: 10.1016/j.neuron.2014.02.030. 2014 | |
| 4 | LHX6 |
| LHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer. | |
| Liu WB, Jiang X, Han F, Li YH, Chen HQ, Liu Y, Cao J, Liu JY. | |
| Cell Death Dis 4:e882. doi: 10.1038/cddis.2013.366. 2013 | |
| 5 | LHX6, PITX2 |
| The LIM homeodomain transcription factor LHX6: a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis. | |
| Zhang Z, Gutierrez D, Li X, Bidlack F, Cao H, Wang J, Andrade K, Margolis HC, Amendt BA. | |
| J Biol Chem 288(4):2485-500. doi: 10.1074/jbc.M112.402933. Epub 2012 Dec 10. 2013 | |
| 6 | LHX6, LHX8 |
| Lhx6 and Lhx8 coordinately induce neuronal expression of Shh that controls the generation of interneuron progenitors. | |
| Flandin P, Zhao Y, Vogt D, Jeong J, Long J, Potter G, Westphal H, Rubenstein JL. | |
| Neuron 70(5):939-50. doi: 10.1016/j.neuron.2011.04.020. 2011 | |
| 7 | LHX6, LHX8 |
| The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. | |
| Denaxa M, Sharpe PT, Pachnis V. | |
| Dev Biol 333(2):324-36. doi: 10.1016/j.ydbio.2009.07.001. Epub 2009 Jul 8. 2009 | |
| 8 | LHX6, LHX8 |
| LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons. | |
| Fragkouli A, van Wijk NV, Lopes R, Kessaris N, Pachnis V. | |
| Development 136(22):3841-51. doi: 10.1242/dev.038083. 2009 | |
| 9 | ARX, DLX1, DLX2, EMX1, EMX2, GSX2, LHX1, LHX5, LHX2, LHX6, LHX8, NKX2-1, OTX1, OTX2, PAX6 |
| Homeobox genes in vertebrate forebrain development and disease. | |
| Wigle JT, Eisenstat DD. | |
| Clin Genet 73(3):212-26. Epub 2008 Jan 31. Review. 2008 | |
| 10 | LHX6, NKX2-1 |
| NKX2.1 specifies cortical interneuron fate by activating Lhx6. | |
| Du T, Xu Q, Ocbina PJ, Anderson SA. | |
| Development 135(8):1559-67. Epub 2008 Mar 13.PMID: 18339674 2008 | |
| 11 | LHX6 |
| Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. | |
| Liodis P, Denaxa M, Grigoriou M, Akufo-Addo C, Yanagawa Y, Pachnis V. | |
| J Neurosci 27(12):3078-89. 2007 | |
| 12 | LHX6 |
| LHX6 is a sensitive methylation marker in head and neck carcinomas. | |
| Estˇcio MR, Youssef EM, Rahal P, Fukuyama EE, G—is-Filho JF, Maniglia JV, Goloni-Bertollo EM, Issa JP, Tajara EH. | |
| Oncogene 25(36):5018-26. Epub 2006 May 29. 2006 | |
| 13 | AIF1L, ANKHD1, ANKRD20A1, ANKRD27, ANKRD32, APH1B, APOLD1, ARMC4, ATXN10, C10orf10, C10orf10, C10orf118, C2orf14, C2orf16, C6orf60, C6orf62, C8orf71, CALCOCO1, CAMKK1, CCDC113, CCDC135, CCDC9, CCDC90B, CCNB2, CD99L2, CHPF, CLIC4, CLPB, CRELD1, CYBRD1, DDX47, DHRS7B, ESPN, FIP1L1, FLYWCH1, FYTTD1, GABARAPL1, GOLT1B, GPS2, GRIPAP1, HIGD1A, IER3IP1, KIF18A, KIRREL2, KLC2, LHX6, LMAN2L, MAF1, MED23, MIS12, MOB4, MYCBPAP, NCALD, NELF, NELFB, NRBF2, NRIP2, NRIP2, NRSN2, NUDT12, PCBD2, PMFBP1, PRPF31, PRSS23, QRSL1, RGMA, RGMB, RNF123, RNF146, RWDD3, SAMHD1, SECISBP2, SEMA4F, SERBP1, SERP1, SH3BP5L, SLC25A24, SLC25A39, SLC37A3, SLC41A2, SLC6A16, SMC6, SPEF1, STMN2, TARDBP, TBC1D3, TBL2, TFIP11, TIGD6, TIMMDC1, TMEM117, TMEM186, TNB, TRAF7, TRAPPC8, TSC22D3, TSPAN14, TWF2, UBA5, UNC50, WDR24, WDR37, WDR91, WSB1, YIPF3, ZC3H13, ZMYND12, ZMYND15, ZRANB3 |
| Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. | |
| Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A. | |
| Genome Res 11(3):422-35. 2001 | |
| 14 | ADIPOR1, AIG1, AMDHD2, ANKHD1, ANKRD20A1, ANKRD27, ANKRD32, APH1A, APH1B, APIP, APOLD1, ARS2, ASCC1, ATXN10, BOLA1, C10orf10, C14orf166, C19orf56, C20orf109, C20orf4, C2orf14, C2orf16, C6orf60, C6orf62, CALCOCO1, CAMKK1, CCDC113, CCDC53, CCDC9, CCNB2, CD99L2, CDK5RAP1, CDK5RAP1, CGI-96, CHMP5, CHPF, CIAO2B, CLIC4, CLPB, COPZ1, COQ4, COQ6, CRELD1, CUTC, CYBRD1, DDX47, DERA, DHRS7, DHRS7B, DHRS7B, DPH5, DTNB, DYNC1LI2, EEF1AKNMT, ELOVL1, EMC9, ERGIC3, ESPN, EXOSC1, EXOSC3, FAHD2A, FAM108B1, FAM18B, FAM32A, FAM82B, FCF1, FIP1L1, FLYWCH1, FYTTD1, GABARAPL1, GET4, GLOD4, GLRX2, GOLT1B, GOLT1B, GPR89A, GPS2, GRIPAP1, HDDC2, HDGFRP3, HIGD1A, IER3IP1, IFT52, ISOC1, KIF18A, KIF20B, KIRREL2, KL3, KLC2, LACTB2, LHX6, LMAN2L, LUC7L2, MAF1, MAGMAS, MECR, MED23, MED31, MEMO, METTL9, MIS12, MOABHD5, MOB4, MPC1, MRPL11, MRPL2, MRPL4, MRPL48, MRPS15, MRPS16, MRPS16P2, MRPS18C, MRPS23, MRPS33, MTCH1, MTERF3, MTO1, MYCBPAP, NCALD, NCIE2, NDUFAF1, NELF, NELFB, NFU1, NMD3, NOSIP, NRBF2, NRIP2, NRIP2, NRSN2, NUDT12, OTUD6B, PARVB, PCBD2, PHF20L1, PIGT, PMFBP1, PNAS-4, PRPF31, PRSS23, PTRH2, QRSL1, RBMX2, RGMA, RGMB, RNF103-CHMP3, RNF123, RNF146, RRNAD1, RRP15, RWDD1, RWDD3, SAMHD1, SAMM50, SCCPDH, SECISBP2, SEMA4F, SERBP1, SERBP1, SERP1, SH3BP5L, SIDT2, SLC25A24, SLC25A39, SLC35C2, SLC37A3, SLC41A2, SLC6A16, SLMO2, SMC6, SPEF1, SQRDL, STARD10, STMN2, SYF2, TARDBP, TBC1D3, TBL2, TFB1M, TFIP11, THAP4, THAP4, TIGD6, TIMMDC1, TMED5, TMED7, TMEM47, TPPP3, TRAF7, TRAPPC12, TRAPPC4, TRMT6, TRNT1, TSC22D3, TSPAN14, TWF2, UBE1DC1, UBE2J1, UCHL5, UNC50, USP39, UTP11L, VPS36, WDR37, WDR50, WDR91, WSB1, YARS2, YIPF3, YPEL5, ZC2HC1A, ZC3H13, ZDHHC9, ZMYND12, ZMYND15, ZRANB3 |
| Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. | |
| Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W. | |
| Genome Res 10(5):703-13. 2000 | |
| 15 | LHX6 |
| A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains. | |
| Kimura N, Ueno M, Nakashima K, Taga T. | |
| J Biochem (Tokyo) 126(1):180-7. 1999 | |