| 1 | AFP, LHX4
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| Downregulation of alpha-fetoprotein expression by LHX4: a critical role in hepatocarcinogenesis.
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| Hung TM, Hu RH, Ho CM, Chiu YL, Lee JL, Jeng YM, Shih DT, Lee PH.
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| Carcinogenesis 32(12):1815-23. doi: 10.1093/carcin/bgr219. Epub 2011 Sep 28.
2011
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| 2 | LHX4, PCDST
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| A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism.
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| Castinetti F, Saveanu A, Reynaud R, Quentien MH, Buffin A, Brauner R, Kaffel N, Albarel F, Guedj AM, El Kholy M, Amin M, Enjalbert A, Barlier A, Brue T.
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| J Clin Endocrinol Metab 93(7):2790-9. Epub 2008 Apr 29. 2008
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| 3 | LHX4, PCDST
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| Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies.
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| Pfaeffle RW, Hunter CS, Savage JJ, Duran-Prado M, Mullen RD, Neeb ZP, Eiholzer U, Hesse V, Haddad NG, Stobbe HM, Blum WF, Weigel JF, Rhodes SJ.
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| J Clin Endocrinol Metab 93(3):1062-71. Epub 2007 Dec 11.
2008
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| 4 | LHX4, SS18
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| The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4.
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| de Bruijn DR, van Dijk AH, Willemse MP, van Kessel AG.
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| Oncogene 27(5):653-62. Epub 2007 Jul 30.PMID: 17667940 2008
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| 5 | LHX3, LHX4
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| Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development.
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| Mullen RD, Colvin SC, Hunter CS, Savage JJ, Walvoord EC, Bhangoo AP, Ten S, Weigel J, Pfäffle RW, Rhodes SJ.
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| Mol Cell Endocrinol 265-266:190-5. Epub 2007 Jan 8. Review.
2007
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| 6 | LHX4, PCDST
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| A novel missense mutation (P366T) of the LHX4 gene causes severe combined pituitary hormone deficiency with pituitary hypoplasia, ectopic posterior lobe and a poorly developed sella turcica.
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| Tajima T, Hattori T, Nakajima T, Okuhara K, Tsubaki J, Fujieda K.
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| Endocr J 54(4):637-41. Epub 2007 May 25.PMID: 17527005 2007
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| 7 | LHX4
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| A novel chromosomal translocation t(1;14)(q25;q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4.
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| Kawamata N, Sakajiri S, Sugimoto KJ, Isobe Y, Kobayashi H, Oshimi K.
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| Oncogene 21(32):4983-91. 2002
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| 8 | LHX4, PROP1
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| Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia.
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| Raetzman LT, Ward R, Camper SA.
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| Development 129(18):4229-39. 2002
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| 9 | PCDST, LHX4
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| Syndromic short stature in patients with a germline mutation in the LIM homeobox LHX4.
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| Machinis K, Pantel J, Netchine I, Leger J, Camand OJ, Sobrier ML, Dastot-Le Moal F, Duquesnoy P, Abitbol M, Czernichow P, Amselem S.
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| Am J Hum Genet 69(5):961-8. Epub 2001 Sep 20. 2001
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| 10 | LHX3, LHX4
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| LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons.
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| Sharma K, Sheng HZ, Lettieri K, Li H, Karavanov A, Potter S, Westphal H, Pfaff SL.
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| Cell 95(6):817-28. 1998
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| 11 | LHX3, LHX4
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| Multistep control of pituitary organogenesis.
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| Sheng HZ, Moriyama K, Yamashita T, Li H, Potter SS, Mahon KA, Westphal H.
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| Science 278(5344):1809-12. 1997
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| 12 | LHX4
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| Lhx4, a LIM homeobox gene.
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| Yamashita T, Moriyama K, Sheng HZ, Westphal H.
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| Genomics 44(1):144-6. 1997
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