Citations for
1AFP, LHX4
Downregulation of alpha-fetoprotein expression by LHX4: a critical role in hepatocarcinogenesis.
Hung TM, Hu RH, Ho CM, Chiu YL, Lee JL, Jeng YM, Shih DT, Lee PH.
Carcinogenesis 32(12):1815-23. doi: 10.1093/carcin/bgr219. Epub 2011 Sep 28. 2011
2LHX4, PCDST
A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism.
Castinetti F, Saveanu A, Reynaud R, Quentien MH, Buffin A, Brauner R, Kaffel N, Albarel F, Guedj AM, El Kholy M, Amin M, Enjalbert A, Barlier A, Brue T.
J Clin Endocrinol Metab 93(7):2790-9. Epub 2008 Apr 29. 2008
3LHX4, PCDST
Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies.
Pfaeffle RW, Hunter CS, Savage JJ, Duran-Prado M, Mullen RD, Neeb ZP, Eiholzer U, Hesse V, Haddad NG, Stobbe HM, Blum WF, Weigel JF, Rhodes SJ.
J Clin Endocrinol Metab 93(3):1062-71. Epub 2007 Dec 11. 2008
4LHX4, SS18
The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4.
de Bruijn DR, van Dijk AH, Willemse MP, van Kessel AG.
Oncogene 27(5):653-62. Epub 2007 Jul 30.PMID: 17667940 2008
5LHX3, LHX4
Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development.
Mullen RD, Colvin SC, Hunter CS, Savage JJ, Walvoord EC, Bhangoo AP, Ten S, Weigel J, Pfäffle RW, Rhodes SJ.
Mol Cell Endocrinol 265-266:190-5. Epub 2007 Jan 8. Review. 2007
6LHX4, PCDST
A novel missense mutation (P366T) of the LHX4 gene causes severe combined pituitary hormone deficiency with pituitary hypoplasia, ectopic posterior lobe and a poorly developed sella turcica.
Tajima T, Hattori T, Nakajima T, Okuhara K, Tsubaki J, Fujieda K.
Endocr J 54(4):637-41. Epub 2007 May 25.PMID: 17527005 2007
7LHX4
A novel chromosomal translocation t(1;14)(q25;q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4.
Kawamata N, Sakajiri S, Sugimoto KJ, Isobe Y, Kobayashi H, Oshimi K.
Oncogene 21(32):4983-91. 2002
8LHX4, PROP1
Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia.
Raetzman LT, Ward R, Camper SA.
Development 129(18):4229-39. 2002
9PCDST, LHX4
Syndromic short stature in patients with a germline mutation in the LIM homeobox LHX4.
Machinis K, Pantel J, Netchine I, Leger J, Camand OJ, Sobrier ML, Dastot-Le Moal F, Duquesnoy P, Abitbol M, Czernichow P, Amselem S.
Am J Hum Genet 69(5):961-8. Epub 2001 Sep 20. 2001
10LHX3, LHX4
LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons.
Sharma K, Sheng HZ, Lettieri K, Li H, Karavanov A, Potter S, Westphal H, Pfaff SL.
Cell 95(6):817-28. 1998
11LHX3, LHX4
Multistep control of pituitary organogenesis.
Sheng HZ, Moriyama K, Yamashita T, Li H, Potter SS, Mahon KA, Westphal H.
Science 278(5344):1809-12. 1997
12LHX4
Lhx4, a LIM homeobox gene.
Yamashita T, Moriyama K, Sheng HZ, Westphal H.
Genomics 44(1):144-6. 1997