| 1 | ADAM22, LCCS12, LGI4
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| Loss-of-Function Mutations in LGI4, a Secreted Ligand Involved in Schwann Cell Myelination, Are Responsible for Arthrogryposis Multiplex Congenita.
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| Xue S, Maluenda J, Marguet F, Shboul M, Quevarec L, Bonnard C, Ng AY, Tohari S, Tan TT, Kong MK, Monaghan KG, Cho MT, Siskind CE, Sampson JB, Rocha CT, Alkazaleh F, Gonzales M, Rigonnot L, Whalen S, Gut M, Gut I, Bucourt M, Venkatesh B, Laquerrière A, Reversade B, Melki J.
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| Am J Hum Genet 100(4):659-665. doi: 10.1016/j.ajhg.2017.02.006. Epub 2017 Mar 16. 2017
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| 2 | LGI1, LGI2, LGI4
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| LGI proteins in the nervous system.
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| Kegel L, Aunin E, Meijer D, Bermingham JR.
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| ASN Neuro 5(3):167-81. doi: 10.1042/AN20120095. Review.
2013
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| 3 | LGI4
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| Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system.
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| Nishino J, Saunders TL, Sagane K, Morrison SJ.
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| J Neurosci 30(45):15228-40. doi: 10.1523/JNEUROSCI.2286-10.2010.
2010
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| 4 | LGI4
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| Positive association between benign familial infantile convulsions and LGI4.
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| Ishii A, Zhang B, Kaneko S, Hirose S.
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| Brain Dev 32(7):538-43. doi: 10.1016/j.braindev.2009.09.006. Epub 2009 Oct 7.
2010
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| 5 | ADAM22, LGI4
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| Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling.
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| Ozkaynak E, Abello G, Jaegle M, van Berge L, Hamer D, Kegel L, Driegen S, Sagane K, Bermingham JR Jr, Meijer D.
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| J Neurosci 30(10):3857-64. doi: 10.1523/JNEUROSCI.6287-09.2010.
2010
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| 6 | EPT, LGI1, LGI4
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| Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy.
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| Zhou YD, Lee S, Jin Z, Wright M, Smith SE, Anderson MP.
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| Nat Med 15(10):1208-14. Epub 2009 Aug 23.PMID: 19701204 2009
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| 7 | LGI4
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| Positive association between benign familial infantile convulsions and LGI4.
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| Ishii A, Zhang B, Kaneko S, Hirose S.
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| Brain Dev rain Dev. 2009 Oct 6. [Epub ahead of print]PMID: 19815358 2009
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| 8 | ADAM11, ADAM22, ADAM23, LGI1, LGI4
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| LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11.
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| Sagane K, Ishihama Y, Sugimoto H.
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| Int J Biol Sci 4(6):387-96. Epub 2008 Oct 21.PMID: 18974846 2008
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| 9 | LGI4
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| The claw paw mutation reveals a role for Lgi4 in peripheral nerve development.
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| Bermingham JR Jr, Shearin H, Pennington J, O'Moore J, Jaegle M, Driegen S, van Zon A, Darbas A, Ozkaynak E, Ryu EJ, Milbrandt J, Meijer D.
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| Nat Neurosci 9(1):76-84. Epub 2005 Dec 11.PMID: 16341215 2006
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| 10 | LGI1, LGI2, LGI3, LGI4, EPT
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| ADPEAF mutations reduce levels of secreted LGI1, a putative tumor suppressor protein linked to epilepsy.
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| Senechal KR, Thaller C, Noebels JL.
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| Hum Mol Genet 14(12):1613-20. Epub 2005 Apr 27. 2005
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| 11 | LGI4
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| Genotypic association of exonic LGI4 polymorphisms and childhood absence epilepsy.
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| Gu W, Sander T, Becker T, Steinlein OK.
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| Neurogenetics 5(1):41-4. Epub 2003 Sep 19.PMID: 14505228 2004
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| 12 | LGI1, LGI2, LGI3, LGI4
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| The LGI1 gene involved in lateral temporal lobe epilepsy belongs to a new subfamily of leucine-rich repeat proteins.
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| Gu W, Wevers A, Schroder H, Grzeschik KH, Derst C, Brodtkorb E, de Vos R, Steinlein OK.
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| FEBS Lett 519(1-3):71-6. 2002
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| 13 | ADGRV1, LGI1, LGI2, LGI3, LGI4, TSPEAR
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| A common protein interaction domain links two recently identified epilepsy genes.
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| Scheel H, Tomiuk S, Hofmann K.
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| Hum Mol Genet 11(15):1757-62. 2002
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