| 1 | LAMP2, LGALS9
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| Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.
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| Sudhakar JN, Lu HH, Chiang HY, Suen CS, Hwang MJ, Wu SY, Shen CN, Chang YM, Li FA, Liu FT, Shui JW.
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| Nat Commun. Aug 27;11(1):4286. doi: 10.1038/s41467-020-18102-7. 2020
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| 2 | LGALS1, LGALS4, lGALS9
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| Prognostic and diagnostic significance of galectins in pancreatic cancer: a systematic review and meta-analysis.
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| Sun Q, Zhang Y, Liu M, Ye Z, Yu X, Xu X, Qin Y.
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| Cancer Cell Int 19:309. doi: 10.1186/s12935-019-1025-5. eCollection 2019. Review.
2019
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| 3 | LGALS9
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| Astrocyte galectin-9 potentiates microglial TNF secretion.
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| Steelman AJ, Li J.
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| J Neuroinflammation 11:144. doi: 10.1186/s12974-014-0144-0.
2014
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| 4 | HAVCR2, LGALS9
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| Regulation of osteoclastogenesis through Tim-3: possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction.
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| Moriyama K, Kukita A, Li YJ, Uehara N, Zhang JQ, Takahashi I, Kukita T.
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| Lab Invest 94(11):1200-11. doi: 10.1038/labinvest.2014.107. Epub 2014 Sep 29.
2014
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| 5 | LGALS9
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| Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells.
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| Wu C, Thalhamer T, Franca RF, Xiao S, Wang C, Hotta C, Zhu C, Hirashima M, Anderson AC, Kuchroo VK.
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| Immunity 41(2):270-82. doi: 10.1016/j.immuni.2014.06.011. Epub 2014 Jul 24.
2014
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| 6 | HAVCR2, LGALS9
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| Galectin-9 signaling through TIM-3 is involved in neutrophil-mediated Gram-negative bacterial killing: an effect abrogated within the cystic fibrosis lung.
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| Vega-Carrascal I, Bergin DA, McElvaney OJ, McCarthy C, Banville N, Pohl K, Hirashima M, Kuchroo VK, Reeves EP, McElvaney NG.
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| J Immunol 192(5):2418-31. doi: 10.4049/jimmunol.1300711. Epub 2014 Jan 29.
2014
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| 7 | LGALS9
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| Galectin-9 enhances cytokine secretion, but suppresses survival and degranulation, in human mast cell line.
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| Kojima R, Ohno T, Iikura M, Niki T, Hirashima M, Iwaya K, Tsuda H, Nonoyama S, Matsuda A, Saito H, Matsumoto K, Nakae S.
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| PLoS One 9(1):e86106. doi: 10.1371/journal.pone.0086106. eCollection 2014.
2014
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| 8 | LGALS9
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| Endothelial LGALS9 splice variant expression in endothelial cell biology and angiogenesis.
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| Heusschen R, Schulkens IA, van Beijnum J, Griffioen AW, Thijssen VL.
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| Biochim Biophys Acta 1842(2):284-92. doi: 10.1016/j.bbadis.2013.12.003. Epub 2013 Dec 12.
2014
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| 9 | LGALS9
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| Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
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| Steelman AJ, Smith R 3rd, Welsh CJ, Li J.
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| J Biol Chem 288(33):23776-87. doi: 10.1074/jbc.M113.451658. Epub 2013 Jul 8.
2013
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| 10 | LGALS9
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| Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.
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| Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Müller I.
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| Eur J Immunol 43(10):2741-9. doi: 10.1002/eji.201343335. Epub 2013 Jul 23.
2013
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| 11 | LGALS9
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| Galectin-9 functionally impairs natural killer cells in humans and mice.
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| Golden-Mason L, McMahan RH, Strong M, Reisdorph R, Mahaffey S, Palmer BE, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen HR.
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| J Virol 87(9):4835-45. doi: 10.1128/JVI.01085-12. Epub 2013 Feb 13.
2013
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| 12 | LGALS9
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| Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection.
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| Elahi S, Niki T, Hirashima M, Horton H.
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| Blood 119(18):4192-204. doi: 10.1182/blood-2011-11-389585. Epub 2012 Mar 21.
2012
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| 13 | LGALS9
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| Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.
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| Oomizu S, Arikawa T, Niki T, Kadowaki T, Ueno M, Nishi N, Yamauchi A, Hirashima M.
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| Clin Immunol 143(1):51-8. doi: 10.1016/j.clim.2012.01.004. Epub 2012 Jan 17.
2012
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| 14 | HAVCR2, LGALS9
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| Galectin-9 regulates T helper cell function independently of Tim-3.
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| Su EW, Bi S, Kane LP.
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| Glycobiology 21(10):1258-65. doi: 10.1093/glycob/cwq214. Epub 2010 Dec 27.
2011
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| 15 | CD44, LGALS9
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| Galectin-9 induces osteoblast differentiation through the CD44/Smad signaling pathway.
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| Tanikawa R, Tanikawa T, Hirashima M, Yamauchi A, Tanaka Y.
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| Biochem Biophys Res Commun 394(2):317-22. Epub 2010 Mar 3. 2010
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| 16 | HAVCR2, LGALS9
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| Tim3 binding to galectin-9 stimulates antimicrobial immunity.
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| Jayaraman P, Sada-Ovalle I, Beladi S, Anderson AC, Dardalhon V, Hotta C, Kuchroo VK, Behar SM.
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| J Exp Med 207(11):2343-54. doi: 10.1084/jem.20100687. Epub 2010 Oct 11.
2010
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| 17 | AIFM1, HDAC2, HTRA1, LGALS9, MX1, NR4A2, PRDX2, TFNA13, UNC5D
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| Left ventricular global transcriptional profiling in human end-stage dilated cardiomyopathy.
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| Colak D, Kaya N, Al-Zahrani J, Al Bakheet A, Muiya P, Andres E, Quackenbush J, Dzimiri N.
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| Genomics 94(1):20-31. Epub 2009 Mar 28.
2009
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| 18 | LGALS9
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| Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.
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| Niki T, Tsutsui S, Hirose S, Aradono S, Sugimoto Y, Takeshita K, Nishi N, Hirashima M.
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| J Biol Chem 284(47):32344-52. Epub 2009 Sep 23.
2009
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| 19 | LGALS9
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| Detection of the Tim-3 ligand, galectin-9, inside the allograft during a rejection episode.
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| Naka EL, Ponciano VC, Cenedeze MA, Pacheco-Silva A, Cāmara NO.
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| Int Immunopharmacol 9(6):658-62. Epub 2008 Dec 25.
2009
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| 20 | LGALS9
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| Different roles of galectin-9 isoforms in modulating E-selectin expression and adhesion function in LoVo colon carcinoma cells.
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| Zhang F, Zheng M, Qu Y, Li J, Ji J, Feng B, Lu A, Li J, Wang M, Liu B.
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| Mol Biol Rep 36(5):823-30. Epub 2008 Apr 10.
2009
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| 21 | LGALS9
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| Intracellular galectin-9 activates inflammatory cytokines in monocytes.
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| Matsuura A, Tsukada J, Mizobe T, Higashi T, Mouri F, Tanikawa R, Yamauchi A, Hirashima M, Tanaka Y.
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| Genes Cells 14(4):511-21.
2009
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| 22 | LGALS9
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| Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells.
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| Klibi J, Niki T, Riedel A, Pioche-Durieu C, Souquere S, Rubinstein E, Le Moulec S, Guigay J, Hirashima M, Guemira F, Adhikary D, Mautner J, Busson P.
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| Blood 113(9):1957-66. Epub 2008 Nov 12. Erratum in: Blood. 2009 Oct 29;114(18):3974. Moulec, Sylvestre L E [corrected to Le Moulec, Sy 2009
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| 23 | LGALS9
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| Galectin-9 expression links to malignant potential of cervical squamous cell carcinoma.
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| Liang M, Ueno M, Oomizu S, Arikawa T, Shinonaga R, Zhang S, Yamauchi A, Hirashima M.
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| J Cancer Res Clin Oncol 134(8):899-907. Epub 2008 Feb 9.
2008
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| 24 | LGALS9
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| Interaction of galectin-9 with lipid rafts induces osteoblast proliferation through the c-Src/ERK signaling pathway.
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| Tanikawa R, Tanikawa T, Okada Y, Nakano K, Hirashima M, Yamauchi A, Hosokawa R, Tanaka Y.
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| J Bone Miner Res 23(2):278-86.
2008
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| 25 | LGALS9
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| Beneficial effect of galectin 9 on rheumatoid arthritis by induction of apoptosis of synovial fibroblasts.
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| Seki M, Sakata KM, Oomizu S, Arikawa T, Sakata A, Ueno M, Nobumoto A, Niki T, Saita N, Ito K, Dai SY, Katoh S, Nishi N, Tsukano M, Ishikawa K, Yamauchi A, Kuchroo V, Hirashima M.
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| Arthritis Rheum 56(12):3968-76.
2007
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| 26 | LGALS8, LGALS9
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| Galectin-8 and galectin-9 are novel substrates for thrombin.
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| Nishi N, Itoh A, Shoji H, Miyanaka H, Nakamura T.
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| Glycobiology 16(11):15C-20C. Epub 2006 Jul 25.
2006
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| 27 | LGALS9
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| The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.
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| Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khoury SJ, Zheng XX, Strom TB, Kuchroo VK.
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| Nat Immunol 6(12):1245-52. Epub 2005 Nov 13.
2005
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| 28 | LGALS9, RHU1, SLC22A12
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| Molecular identification of a renal urate anion exchanger that regulates blood urate levels.
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| Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H.
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| Nature 417(6887):447-52. 2002
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| 29 | LGALS9
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| Gene expression of galectin-9/ecalectin, a potent eosinophil chemoattractant, and/or the insertional isoform in human colorectal carcinoma cell lines and detection of frame-shift mutations for protein sequence truncations in the second functional lectin domain.
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| Lahm H, Hoeflich A, Andre S, Sordat B, Kaltner H, Wolf E, Gabius HJ.
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| Int J Oncol 17(3):519-24. 2000
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| 30 | LGALS9
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| Human ecalectin, a variant of human galectin-9, is a novel eosinophil chemoattractant produced by T lymphocytes.
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| Matsumoto R, Matsumoto H, Seki M, Hata M, Asano Y, Kanegasaki S, Stevens RL, Hirashima M.
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| J Biol Chem 273(27):16976-84. 1998
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| 31 | LGALS9
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| Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease.
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| Tureci O, Schmitt H, Fadle N, Pfreundschuh M, Sahin U.
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| J Biol Chem 272(10):6416-22. 1997
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