| 1 | LCR-HBA@, LCR-HB-B@
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| Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.
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| Navas PA, Li Q, Peterson KR, Swank RA, Rohde A, Roy J, Stamatoyannopoulos G.
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| Hum Mol Genet 11(8):893-903. 2002
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| 2 | LCR-HBA@
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| Derepression of human embryonic zeta-globin promoter by a locus-control region sequence.
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| Huang BL, et al.
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| Proc Natl Acad Sci U S A 95(25):14669-74. 1998
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| 3 | LCR-HBA@, NPRL3
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| Conservation of position and sequence of a novel, widely expressed gene containing the major human alpha-globin regulatory element.
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| Vyas P, Vickers MA, Picketts DJ, Higgs DR.
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| Genomics 29(3):679-89. 1995
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| 4 | RHBDF1, ATHAL, LCR-HBA@
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| Homology of a 130-kb region enclosing the alpha-globin gene cluster, the alpha-locus controlling region, and two non-globin genes in human and mouse.
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| Kielman MF, Smits R, Devi TS, Fodde R, Bernini LF.
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| Mamm Genome 4(6):314-23. 1993
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| 5 | LCR-HBA@
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| The LCR-like alpha-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiation.
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| Pondel MD, et al.
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| Nucleic Acids Res 20 : 237-243. 1992
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| 6 | LCR-HBA@
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| Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin.
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| Vyas P, et al.
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| Cell 69 : 781-793. 1992
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| 7 | LCR-HBA@
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| Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes.
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| Romao L, et al.
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| Blood 78 : 1589-1595. 1991
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| 8 | LCR-HBA@
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| The human alpha-LCR is flanked by three highly conserved sequences.
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| Kielman MF, et al.
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| Am J Hum Genet 49S : 333. 1991
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| 9 | LCR-HBA@
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| A major positive regulatory region located far upstream of the human alpha-globin gene locus.
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| Higgs DR, et al.
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| Genes Dev 4 : 1588-1601. 1990
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| 10 | LCR-HBA@, LCR-HB-B@, TBX1
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| Globin gene regulation and switching: circa 1990.
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| Orkin SH.
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| Cell 63 : 665-672. 1990
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| 11 | LCR-HBA@
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| Inactivation of human alpha-globin gene expression by a denovo deletion located upstream of the alpha-globin gene cluster.
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| Liebhaber SA, et al.
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| Proc Natl Acad Sci U S A 87 : 9431-9435. 1990
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| 12 | ATHAL, LCR-HBA@
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| Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster.
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| Hatton CS, Wilkie AO, Drysdale HC, Wood WG, Vickers MA, Sharpe J, Ayyub H, Pretorius IM, Buckle VJ, Higgs DR.
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| Blood 76(1):221-7. 1990
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