Citations for
1F2R, LCN2
Role of Lipocalin-2 in Thrombin-Induced Brain Injury.
Mao S, Xi G, Keep RF, Hua Y.
Stroke 47(4):1078-84. doi: 10.1161/STROKEAHA.115.012153. 2016
Urinary ADAM12 and MMP-9/NGAL complex detect the presence of gastric cancer.
Shimura T, Dagher A, Sachdev M, Ebi M, Yamada T, Yamada T, Joh T, Moses MA.
Cancer Prev Res (Phila) 8(3):240-8. doi: 10.1158/1940-6207.CAPR-14-0229. 2015
HIC1 silencing in triple-negative breast cancer drives progression through misregulation of LCN2.
Cheng G, Sun X, Wang J, Xiao G, Wang X, Fan X, Zu L, Hao M, Qu Q, Mao Y, Xue Y, Wang J.
Cancer Res 74(3):862-72. doi: 10.1158/0008-5472.CAN-13-2420. Epub 2013 Dec 2. 2014
Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver.
Asimakopoulou A, Borkham-Kamphorst E, Henning M, Yagmur E, Gassler N, Liedtke C, Berger T, Mak TW, Weiskirchen R.
Biochim Biophys Acta 1842(10):1513-24. doi: 10.1016/j.bbalip.2014.07.017. Epub 2014 Jul 31. 2014
Secreted protein lipocalin-2 promotes microglial M1 polarization.
Jang E, Lee S, Kim JH, Kim JH, Seo JW, Lee WH, Mori K, Nakao K, Suk K.
FASEB J 27(3):1176-90. doi: 10.1096/fj.12-222257. Epub 2012 Dec 3. 2013
Lipocalin 2 is a novel regulator of angiogenesis in human breast cancer.
Yang J, McNeish B, Butterfield C, Moses MA.
FASEB J 27(1):45-50. doi: 10.1096/fj.12-211730. Epub 2012 Sep 14. 2013
Six-transmembrane epithelial antigen of prostate 4 and neutrophil gelatinase-associated lipocalin expression in visceral adipose tissue is related to iron status and inflammation in human obesity.
Catalán V, Gómez-Ambrosi J, Rodríguez A, Ramírez B, Rotellar F, Valentí V, Silva C, Gil MJ, Salvador J, Frühbeck G.
Eur J Nutr 52(6):1587-95. doi: 10.1007/s00394-012-0464-8. Epub 2012 Nov 22. 2013
Regulation by lipocalin-2 of neuronal cell death, migration, and morphology.
Lee S, Lee WH, Lee MS, Mori K, Suk K.
J Neurosci Res 90(3):540-50. doi: 10.1002/jnr.22779. Epub 2011 Oct 31. 2012
Lipocalin-2 ameliorates granulocyte functionality.
Schroll A, Eller K, Feistritzer C, Nairz M, Sonnweber T, Moser PA, Rosenkranz AR, Theurl I, Weiss G.
Eur J Immunol 42(12):3346-57. doi: 10.1002/eji.201142351. Epub 2012 Nov 7. 2012
Lipocalin 2, a new GADD153 target gene, as an apoptosis inducer of endoplasmic reticulum stress in lung cancer cells.
Hsin IL, Hsiao YC, Wu MF, Jan MS, Tang SC, Lin YW, Hsu CP, Ko JL.
Toxicol Appl Pharmacol 263(3):330-7. doi: 10.1016/j.taap.2012.07.005. Epub 2012 Jul 16. 2012
Lipocalin 2: novel component of proinflammatory signaling in Alzheimer's disease.
Naudé PJ, Nyakas C, Eiden LE, Ait-Ali D, van der Heide R, Engelborghs S, Luiten PG, De Deyn PP, den Boer JA, Eisel UL.
FASEB J 26(7):2811-23. doi: 10.1096/fj.11-202457. Epub 2012 Mar 21. 2012
Lipocalin-2 induces cardiomyocyte apoptosis by increasing intracellular iron accumulation.
Xu G, Ahn J, Chang S, Eguchi M, Ogier A, Han S, Park Y, Shim C, Jang Y, Yang B, Xu A, Wang Y, Sweeney G.
J Biol Chem 287(7):4808-17. doi: 10.1074/jbc.M111.275719. Epub 2011 Nov 22. 2012
13LCN2, SLC22A17
Lipocalin-2 (24p3/neutrophil gelatinase-associated lipocalin (NGAL)) receptor is expressed in distal nephron and mediates protein endocytosis.
Langelueddecke C, Roussa E, Fenton RA, Wolff NA, Lee WK, Thévenod F.
J Biol Chem 287(1):159-69. doi: 10.1074/jbc.M111.308296. Epub 2011 Nov 14. 2012
14LCN2, SLC22A17
Expression of NGAL and NGALR in human embryonic, fetal and normal adult tissues.
Zhang PX, Zhang FR, Xie JJ, Tao LH, Lü Z, Xu XE, Shen J, Xu LY, Li EM.
Mol Med Rep 6(4):716-22. doi: 10.3892/mmr.2012.980. Epub 2012 Jul 6. 2012
15CXCL10, LCN2
Lipocalin-2 Is a chemokine inducer in the central nervous system: role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migration.
Lee S, Kim JH, Kim JH, Seo JW, Han HS, Lee WH, Mori K, Nakao K, Barasch J, Suk K.
J Biol Chem 286(51):43855-70. doi: 10.1074/jbc.M111.299248. Epub 2011 Oct 26. 2011
Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation.
Mucha M, Skrzypiec AE, Schiavon E, Attwood BK, Kucerova E, Pawlak R.
Proc Natl Acad Sci U S A 108(45):18436-41. doi: 10.1073/pnas.1107936108. Epub 2011 Oct 3. 2011
Increased plasma levels of lipocalin 2 in mild cognitive impairment.
Choi J, Lee HW, Suk K.
J Neurol Sci 305(1-2):28-33. doi: 10.1016/j.jns.2011.03.023. Epub 2011 Apr 3. 2011
Lipocalin 2 deficiency inhibits cell proliferation, autophagy, and mitochondrial biogenesis in mouse embryonic cells.
Jin D, Zhang Y, Chen X.
Mol Cell Biochem 351(1-2):165-72. doi: 10.1007/s11010-011-0724-6. Epub 2011 Jan 14. 2011
Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditure.
Jin D, Guo H, Bu SY, Zhang Y, Hannaford J, Mashek DG, Chen X.
FASEB J 25(2):754-64. doi: 10.1096/fj.10-165175. Epub 2010 Oct 25. 2011
20LCN2, SLC22A17
Immunohistochemical detection of a specific receptor for lipocalin2 (solute carrier family 22 member 17, SLC22A17) and its prognostic significance in endometrial carcinoma.
Miyamoto T, Asaka R, Suzuki A, Takatsu A, Kashima H, Shiozawa T.
Exp Mol Pathol 91(2):563-8. doi: 10.1016/j.yexmp.2011.06.002. Epub 2011 Jul 8. 2011
21LCN2, SLC22A17
NGAL and NGALR are frequently overexpressed in human gliomas and are associated with clinical prognosis.
Liu MF, Jin T, Shen JH, Shen ZY, Zheng ZC, Zhang ZL, Xu LY, Li EM, Xu HX.
J Neurooncol 104(1):119-27. doi: 10.1007/s11060-010-0486-0. Epub 2010 Dec 24. 2011
NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene.
Fougère M, Gaudineau B, Barbier J, Guaddachi F, Feugeas JP, Auboeuf D, Jauliac S.
Oncogene 29(15):2292-301. Epub 2010 Jan 25.PMID: 20101218 2010
Lipocalin 2 promotes breast cancer progression.
Yang J, Bielenberg DR, Rodig SJ, Doiron R, Clifton MC, Kung AL, Strong RK, Zurakowski D, Moses MA.
Proc Natl Acad Sci U S A 106(10):3913-8. Epub 2009 Feb 23. 2009
Lipocalin 2 is required for pulmonary host defense against Klebsiella infection.
Chan YR, Liu JS, Pociask DA, Zheng M, Mietzner TA, Berger T, Mak TW, Clifton MC, Strong RK, Ray P, Kolls JK.
J Immunol 182(8):4947-56. 2009
25LCN2, LRP2, SLC22A17
Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells.
Miharada K, Hiroyama T, Sudo K, Danjo I, Nagasawa T, Nakamura Y.
J Cell Physiol 215(2):526-37. 2008
Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer.
Tong Z, Kunnumakkara AB, Wang H, Matsuo Y, Diagaradjane P, Harikumar KB, Ramachandran V, Sung B, Chakraborty A, Bresalier RS, Logsdon C, Aggarwal BB, Krishnan S, Guha S.
Cancer Res 68(15):6100-8. 2008
Lipocalin 2 is required for BCR-ABL-induced tumorigenesis.
Leng X, Lin H, Ding T, Wang Y, Wu Y, Klumpp S, Sun T, Zhou Y, Monaco P, Belmont J, Aderem A, Akira S, Strong R, Arlinghaus R.
Oncogene 27(47):6110-9. Epub 2008 Jul 28. 2008
Neutrophil gelatinase-associated lipocalin reflects the severity of renal impairment in subjects affected by chronic kidney disease.
Bolignano D, Lacquaniti A, Coppolino G, Campo S, Arena A, Buemi M.
Kidney Blood Press Res 31(4):255-8. Epub 2008 Jul 5. 2008
The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages.
Zhang J, Wu Y, Zhang Y, Leroith D, Bernlohr DA, Chen X.
Mol Endocrinol 22(6):1416-26. Epub 2008 Feb 21.PMID: 18292240 2008
Lipocalin-2: development, analytical characterization, and clinical testing of a new ELISA.
Stejskal D, Karpísek M, Humenanska V, Hanulova Z, Stejskal P, Kusnierova P, Petzel M.
Horm Metab Res 40(6):381-5. Epub 2008 Mar 31. 2008
31LCN2, SLC22A17
A novel alternative spliced variant of neutrophil gelatinase-associated lipocalin receptor in oesophageal carcinoma cells.
Fang WK, Xu LY, Lu XF, Liao LD, Cai WJ, Shen ZY, Li EM.
Biochem J 403(2):297-303. 2007
Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells.
Hanai J, Mammoto T, Seth P, Mori K, Karumanchi SA, Barasch J, Sukhatme VP.
J Biol Chem 280(14):13641-7. Epub 2005 Feb 3. 2005
33CD74, DEFA5, DEFA6, ESD, CXCL1, IGHG3, IGLL2, LCN2, REG3A, PI3, REG1A, S100A9, S100P
Ulcerative colitis and Crohn's disease : distinctive gene expression profiles and novel susceptibility candidate genes.
Lawrance IC, Fiocchi C, Chakravarti S.
Hum Mol Genet 10(5):445-56. 2001
Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation.
Devireddy LR, Teodoro JG, Richard FA, Green MR.
Science 293(5531):829-34. 2001
A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres.
Lacazette E, Gachon AM, Pitiot G.
Hum Mol Genet 9(2):289-301 2000
Heterogeneous expression of the lipocalin NGAL in primary breast cancers.
Stoesz SP, et al.
Int J Cancer 79 : 565-572. 1998
Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans.
Cowland JB, Borregaard N.
Genomics 45(1):17-23. 1997
The lipocalin protein family: structure and function.
Flower DR.
Biochem J 318 ( Pt 1):1-14. Review 1996
Cloning and expression of human neutrophil lipocalin cDNA derived from bone marrow and ovarian cancer cells.
Bartsch S, et al.
FEBS Lett 357 : 255-259. 1995
Comparative mapping of lipocalin genes in human and mouse : the four genes for complement C8 gamma chain, prostaglandin-D- synthase, oncogene-24P3, and progestagen-associated endometrial protein map to HSA9 and MMU2.
Chan P, et al.
Genomics 23 : 145-150. 1994
Molecular cloning and expression of a cDNA encoding NGAL : a lipocalin expressed in human neutrophils.
Bundgaard JR, et al.
Biochem Biophys Res Commun 202 : 1468-1475. 1994