| 1 | FGL1, LAG3
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| LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
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| Ming Q, Celias DP, Wu C, Cole AR, Singh S, Mason C, Dong S, Tran TH, Amarasinghe GK, Ruffell B, Luca VC.
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| Nat Immunol. Jul;23(7):1031-1041. doi: 10.1038/s41590-022-01238-7. Epub 2022 Jun 27. 2022
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| 2 | LAG3
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| Lymphocyte activation gene-3 (LAG-3) regulatory T cells: An evolving biomarker for treatment response in autoimmune diseases.
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| Gertel S, Polachek A, Elkayam O, Furer V.
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| Autoimmun Rev. Jun;21(6):103085. doi: 10.1016/j.autrev.2022.103085. Epub 2022 Mar 24. 2022
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| 3 | FGL1, LAG3
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| Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target.
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| Qian W, Zhao M, Wang R, Li H.
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| J Hematol Oncol. Sep 15;14(1):147. doi: 10.1186/s13045-021-01161-8. 2021
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| 4 | CTLA4, HAVCR2, LAG3, PDCD1
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| Inhibitory immune checkpoint molecules and exhaustion of T cells in COVID-19. . 2021. PMID:
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| Barnova M, Bobcakova A, Urdova V, Kosturiak R, Kapustova L, Dobrota D, Jesenak M.
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| Physiol Res Dec 16;70(S2):S227-S247. doi: 10.33549/physiolres.934757 2021
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| 5 | LAG3
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| LAG3 (CD223) and autoimmunity: Emerging evidence.
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| Hu S, Liu X, Li T, Li Z, Hu F.
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| J Autoimmun. Aug;112:102504. doi: 10.1016/j.jaut.2020.102504. Epub 2020 Jun 20. 2020
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| 6 | LAG3
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| . LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma.
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| Klümper N, Ralser DJ, Bawden EG, Landsberg J, Zarbl R, Kristiansen G, Toma M, Ritter M, Hölzel M, Ellinger J, Dietrich D
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| J Immunother Cancer. Mar;8(1):e000552. doi: 10.1136/jitc-2020-000552 2020
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| 7 | LAG3
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| Lymphocyte-activation gene 3 (LAG3): The next immune checkpoint receptor
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| Ruffo E, Wu RC, Bruno TC, Workman CJ, Vignali DAA.
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| Semin Immunol. Apr;42:101305. doi: 10.1016/j.smim.2019.101305. 2019
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| 8 | LAG3
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| Protein transport inhibitors downregulate the expression of LAG-3 on regulatory T cells.
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| Anvari S, Grimbergen A, Davis CM, Makedonas G.
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| J Immunol Methods. Aug;447:47-51. doi: 10.1016/j.jim.2017.04.006. Epub 2017 Apr 21 2017
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| 9 | LAG3
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| T-cell polarization: Potential serological markers in preterm and term infants
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| Frezza S, Gallini F, Palazzo R, Carollo M, De Carolis MP, D'Andrea V, Catenazzi P, Romagnoli C, Ausiello CM.
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| Early Hum Dev Oct;101:69-71. doi: 10.1016/j.earlhumdev.2016.03.013. Epub 2016 Jul 11 2016
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| 10 | LAG3
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| Trafficking of LAG-3 to the surface on activated T cells via its cytoplasmic domain and protein kinase C signaling
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| Bae J, Lee SJ, Park CG, Lee YS, Chun T.
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| J Immunol. Sep 15;193(6):3101-12. doi: 10.4049/jimmunol.1401025. Epub 2014 Aug 8. 2014
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| 11 | CTAG1B, LAG3, RPL17
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| Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer.
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| Matsuzaki J, Gnjatic S, Mhawech-Fauceglia P, Beck A, Miller A, Tsuji T, Eppolito C, Qian F, Lele S, Shrikant P, Old LJ, Odunsi K.
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| Proc Natl Acad Sci U S A 107(17):7875-80. Epub 2010 Apr 12. 2010
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| 12 | LAG3
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| High expression of lymphocyte-activation gene 3 (LAG3) in chronic lymphocytic leukemia cells is associated with unmutated immunoglobulin variable heavy chain region (IGHV) gene and reduced treatment-free survival.
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| Kotaskova J, Tichy B, Trbusek M, Francova HS, Kabathova J, Malcikova J, Doubek M, Brychtova Y, Mayer J, Pospisilova S.
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| J Mol Diagn 12(3):328-34. Epub 2010 Mar 12.PMID: 20228263 2010
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| 13 | LAG3
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| LAG-3 regulates plasmacytoid dendritic cell homeostasis.
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| Workman CJ, Wang Y, El Kasmi KC, Pardoll DM, Murray PJ, Drake CG, Vignali DA.
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| J Immunol 182(4):1885-91.PMID: 19201841 2009
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| 14 | LAG3
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| Association analysis of the LAG3 and CD4 genes in multiple sclerosis in two independent populations.
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| Lundmark F, Harbo HF, Celius EG, Saarela J, Datta P, Oturai A, Lindgren CM, Masterman T, Salter H, Hillert J.
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| J Neuroimmunol 180(1-2):193-8. Epub 2006 Oct 3.PMID: 17020785 2006
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| 15 | IL7R, LAG3
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| Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis.
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| Zhang Z, Duvefelt K, Svensson F, Masterman T, Jonasdottir G, Salter H, Emahazion T, Hellgren D, Falk G, Olsson T, Hillert J, Anvret M.
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| Genes Immun 6(2):145-52.PMID: 15674389 2005
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| 16 | LAG3
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| Cloning of rat lymphocyte activation gene-3 (Lag3; CD223) cDNA and its mRNA expression in rat tissues.
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| Chun T, Cho HS, Chung YH.
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| Eur J Immunogenet 31(1):5-9.PMID: 15009174 2004
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| 17 | LAG3
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| MHC class II signal transduction in human dendritic cells induced by a natural ligand, the LAG-3 protein (CD223).
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| Andreae S, Buisson S, Triebel F.
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| Blood 102(6):2130-7. Epub 2003 May 29. 2003
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| 18 | LAG3
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| Maturation and activation of dendritic cells induced by lymphocyte activation gene-3 (CD223).
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| Andreae S, Piras F, Burdin N, Triebel F.
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| J Immunol 168(8):3874-80. 2002
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| 19 | LAG3
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| Regulation of expression of the human lymphocyte activation gene-3 (LAG-3) molecule, a ligand for MHC class II.
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| Bruniquel D, Borie N, Hannier S, Triebel F.
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| Immunogenetics 48 : 116-124. 1998
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| 20 | CD4, LAG3, PTMS
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| Genomic organization of the human LAG-3/CD4 locus.
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| Bruniquel D, et al.
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| Immunogenetics 47 : 96-98. 1997
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| 21 | LAG3
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| LAG-3, a novel lymphocyte activation gene closely related to CD4.
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| Triebel F, et al.
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| J Exp Med 171 : 1393-1405. 1990
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