1 | KRT18, KRT8
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| Changes in keratin 8/18 expression in human granulosa cell lineage are associated to cell death/survival events: potential implications for the maintenance of the ovarian reserve.
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| Gaytan F, Morales C, Roa J, Tena-Sempere M.
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| Hum Reprod 33(4):680-689. doi: 10.1093/humrep/dey010.
2018
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2 | KRT18, KRT8, NOTCH1
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| Keratins regulate colonic epithelial cell differentiation through the Notch1 signalling pathway.
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| Lähdeniemi IAK, Misiorek JO, Antila CJM, Landor SK, Stenvall CA, Fortelius LE, Bergström LK, Sahlgren C, Toivola DM.
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| Cell Death Differ 24(6):984-996. doi: 10.1038/cdd.2017.28. Epub 2017 May 5.
2017
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3 | KRT18
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| Cytokeratin 18 is necessary for initiation of TGF-β1-induced epithelial-mesenchymal transition in breast epithelial cells.
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| Jung H, Kim B, Moon BI, Oh ES.
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| Mol Cell Biochem 423(1-2):21-28. Epub 2016 Oct 13.
2016
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4 | KRT18
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| Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis.
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| Bettermann K, Mehta AK, Hofer EM, Wohlrab C, Golob-Schwarzl N, Svendova V, Schimek MG, Stumptner C, Thüringer A, Speicher MR, Lackner C, Zatloukal K, Denk H, Haybaeck J.
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| Oncotarget 7(45):73309-73322. doi: 10.18632/oncotarget.12325.
2016
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5 | KRT18, KRT8
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| Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18.
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| Kakade PS, Budnar S, Kalraiya RD, Vaidya MM.
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| J Biol Chem 291(23):12003-13. doi: 10.1074/jbc.M116.728717. Epub 2016 Apr 8.
2016
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6 | ARHGEF40, KRT18, KRT8, RHOA
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| Interplay between Solo and keratin filaments is crucial for mechanical force-induced stress fiber reinforcement.
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| Fujiwara S, Ohashi K, Mashiko T, Kondo H, Mizuno K.
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| Mol Biol Cell 27(6):954-66. doi: 10.1091/mbc.E15-06-0417. Epub 2016 Jan 28.
2016
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7 | KRT18
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| Serum caspase-cleaved cytokeratin-18 levels and outcomes after aneurysmal subarachnoid hemorrhage.
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| Yuan ZG, Wang JL, Jin GL, Yu XB, Li JQ, Qiu TL, Dai RX.
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| J Neurol Sci 359(1-2):298-304. doi: 10.1016/j.jns.2015.11.020. Epub 2015 Nov 12.
2015
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8 | KRT18
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| Correlation between serum cytokeratin-18 and the progression or regression of non-alcoholic fatty liver disease.
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| Kawanaka M, Nishino K, Nakamura J, Urata N, Oka T, Goto D, Suehiro M, Kawamoto H, Yamada G.
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| Ann Hepatol 14(6):837-44. doi: 10.5604/16652681.1171767.
2015
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9 | KRT18, KRT8, TNF
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| Tumor necrosis factor-α confers cardioprotection through ectopic expression of keratins K8 and K18.
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| Papathanasiou S, Rickelt S, Soriano ME, Schips TG, Maier HJ, Davos CH, Varela A, Kaklamanis L, Mann DL, Capetanaki Y.
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| Nat Med 21(9):1076-84. doi: 10.1038/nm.3925. Epub 2015 Aug 17.
2015
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10 | EGR1, KRT18
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| EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression.
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| Zhang H, Chen X, Wang J, Guang W, Han W, Zhang H, Tan X, Gu Y.
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| Sci Rep 4:5416. doi: 10.1038/srep05416.
2014
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11 | KRT18
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| Cytokeratin 18 is not required for morphogenesis of developing prostates but contributes to adult prostate regeneration.
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| Zhang C, Guo Y, Cui J, Zhu HH, Gao WQ.
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| Biomed Res Int 2013:576472. doi: 10.1155/2013/576472. Epub 2013 Dec 30.
2013
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12 | KRT18
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| Increased plasma levels of CK-18 as potential cell death biomarker in patients with HELLP syndrome.
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| John K, Wielgosz S, Schulze-Osthoff K, Bantel H, Hass R.
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| Cell Death Dis 4:e886. doi: 10.1038/cddis.2013.408.
2013
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13 | KRT18
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| Serum cytokeratin-18 fragment levels are useful biomarkers for nonalcoholic steatohepatitis in children.
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| Feldstein AE, Alkhouri N, De Vito R, Alisi A, Lopez R, Nobili V.
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| Am J Gastroenterol 108(9):1526-31. doi: 10.1038/ajg.2013.168. Epub 2013 Jun 11.
2013
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14 | KRT18, KRT8
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| Keratin 8 is required for the maintenance of architectural structure in thymus epithelium.
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| Odaka C, Loranger A, Takizawa K, Ouellet M, Tremblay MJ, Murata S, Inoko A, Inagaki M, Marceau N.
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| PLoS One 8(9):e75101. doi: 10.1371/journal.pone.0075101. eCollection 2013.
2013
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15 | CFTR, KRT18
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| Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.
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| Duan Y, Sun Y, Zhang F, Zhang WK, Wang D, Wang Y, Cao X, Hu W, Xie C, Cuppoletti J, Magin TM, Wang H, Wu Z, Li N, Huang P.
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| J Biol Chem 287(48):40547-59. doi: 10.1074/jbc.M112.403584. Epub 2012 Oct 8.
2012
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16 | KRT18, KRT8
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| Keratin 8/18 regulation of cell stiffness-extracellular matrix interplay through modulation of Rho-mediated actin cytoskeleton dynamics.
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| Bordeleau F, Myrand Lapierre ME, Sheng Y, Marceau N.
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| PLoS One 7(6):e38780. doi: 10.1371/journal.pone.0038780. Epub 2012 Jun 7.
2012
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17 | KRT18
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| Increased total cytokeratin-18 serum and urine levels in chronic kidney disease.
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| Roth GA, Lebherz-Eichinger D, Ankersmit HJ, Hacker S, Hetz H, Vukovich T, Perne A, Reiter T, Farr A, Hörl WH, Haas M, Krenn CG.
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| Clin Chim Acta 412(9-10):713-7. doi: 10.1016/j.cca.2010.12.030. Epub 2010 Dec 31.
2011
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18 | KRT18, KRT8
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| Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma.
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| Yamashiro Y, Takei K, Umikawa M, Asato T, Oshiro M, Uechi Y, Ishikawa T, Taira K, Uezato H, Kariya K.
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| Biochem Biophys Res Commun 399(3):365-72. Epub 2010 Jul 24.
2010
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19 | KRT18, CCRH
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| Mutation in keratin 18 induces mitochondrial fragmentation in liver-derived epithelial cells.
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| Kumemura H, Harada M, Yanagimoto C, Koga H, Kawaguchi T, Hanada S, Taniguchi E, Ueno T, Sata M.
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| Biochem Biophys Res Commun 367(1):33-40. Epub 2007 Dec 27. 2008
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20 | KRT18
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| Injury-induced expression of cytokeratins 8 and 18 by vascular smooth muscle cells requires concurrent activation of cytoskeletal and growth factor receptors.
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| Moon MC, Yau L, Wright B, Zahradka P.
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| Can J Physiol Pharmacol 86(5):223-31.
2008
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21 | KRT18
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| A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice.
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| Hesse M, Grund C, Herrmann H, Bröhl D, Franz T, Omary MB, Magin TM.
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| Exp Cell Res 313(14):3127-40. Epub 2007 May 25.
2007
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22 | KRT18, KRT8
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| Identifying the role of specific motifs in the lens fiber cell specific intermediate filament phakosin.
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| Pittenger JT, Hess JF, Fitzgerald PG.
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| Invest Ophthalmol Vis Sci 48(11):5132-41.
2007
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23 | KRT1, KRT10, KRT12, KRT13, KRT14, KRT14P, KRT15, KRT16, KRT17, KRT17P3, KRT18, KRT18P12, KRT18P16, KRT18P17, KRT18P18, KRT18P19, KRT18P20, KRT18P21, KRT18P22, KRT18P23, KRT18P24, KRT18P25, KRT18P26, KRT18P27, KRT18P28, KRT18P29, KRT18P30, KRT18P31, KRT18P32, KRT18P33, KRT18P34, KRT18P35, KRT18P36, KRT18P37, KRT18P38, KRT18P39, KRT18P40, KRT18P41, KRT18P42, KRT18P43, KRT18P44, KRT18P45, KRT18P46, KRT18P47, KRT18P48, KRT18P49, KRT18P5, KRT18P50, KRT18P8, KRT19, KRT19P1, KRT19P2, KRT19P3, KRT2, KRT20, KRT222, KRT23, KRT24, KRT25, KRT26, KRT27, KRT28, KRT3, KRT31, KRT32, KRT33, KRT33A, KRT34, KRT35, KRT36, KRT37, KRT38, KRT39, KRT4, KRT40, KRT5, KRT6A, KRT6B, KRT6C, KRT7, KRT71, KRT72, KRT73, KRT74, KRT75, KRT76, KRT77, KRT78, KRT79, KRT8, KRT80, KRT81, KRT82, KRT83, KRT84, KRT85, KRT86, KRT8P10, KRT8P13, KRT8P15, KRT8P17, KRT8P18, KRT8P19, KRT8P20, KRT8P21, KRT8P22, KRT8P23, KRT8P24, KRT8P25, KRT8P26, KRT8P27, KRT8P28, KRT8P29, KRT8P30, KRT8P5, KRT8P6, KRT8P7, KRT8P8, KRT8P9, KRT9, KRTAP19-8, KRTAP20-4
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| New consensus nomenclature for mammalian keratins.
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| Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW.
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| J Cell Biol 174(2):169-74. Epub 2006 Jul 10. 2006
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24 | TCHP, KRT16, KRT18
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| Identification of trichoplein, a novel keratin filament-binding protein.
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| Nishizawa M, Izawa I, Inoko A, Hayashi Y, Nagata K, Yokoyama T, Usukura J, Inagaki M.
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| J Cell Sci 118(Pt 5):1081-90. 2005
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25 | ELF5, KRT18
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| Epithelium-specific ets transcription factor 2 upregulates cytokeratin 18 expression in pulmonary epithelial cells through an interaction with cytokeratin 18 intron 1.
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| Yaniw D, Hu J.
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| Cell Res 15(6):423-9.
2005
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26 | KRT18, KRT23, KRT24, KRT25
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| The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.
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| Rogers MA, Winter H, Langbein L, Bleiler R, Schweizer J.
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| Differentiation 72(9-10):527-40.
2004
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27 | CCRH, KRT18
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| Mutation of human keratin 18 in association with cryptogenic cirrhosis.
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| Ku NO, et al.
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| J Clin Invest 99 : 19-23. 1997
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28 | KRT18
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| Molecular characterization of a tissue-polypeptide-specific-antigen epitope and its relationship to human cytokeratin 18.
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| Rydlander L, et al.
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| Eur J Biochem 241 : 309-314. 1996
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29 | PRPH, KRT18
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| Peripherin gene is linked to keratin 18 gene on human chromosome 12.
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| Blumenfeld A, et al.
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| Somat Cell Mol Genet 21 : 83-88. 1995
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30 | KRT18
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| Localization of the gene for human simple epithelial keratin 18 to chromosome 12 using polymerase chain reaction.
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| Waseem A, et al.
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| Genomics 7 : 188-194. 1990
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31 | KRT18
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| Cytokeratin expression in simple epithelia. I. Identification of mRNA coding for human cytokeratin no. 18 by a cDNA clone.
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| Romano V, Hatzfeld M, Magin TM, Zimbelmann R, Franke WW, Maier G, Ponstingl H.
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| Differentiation 30(3):244-53. 1986
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