Citations for
1KRT18, KRT8
Changes in keratin 8/18 expression in human granulosa cell lineage are associated to cell death/survival events: potential implications for the maintenance of the ovarian reserve.
Gaytan F, Morales C, Roa J, Tena-Sempere M.
Hum Reprod 33(4):680-689. doi: 10.1093/humrep/dey010. 2018
2KRT18, KRT8, NOTCH1
Keratins regulate colonic epithelial cell differentiation through the Notch1 signalling pathway.
Lähdeniemi IAK, Misiorek JO, Antila CJM, Landor SK, Stenvall CA, Fortelius LE, Bergström LK, Sahlgren C, Toivola DM.
Cell Death Differ 24(6):984-996. doi: 10.1038/cdd.2017.28. Epub 2017 May 5. 2017
3KRT18
Cytokeratin 18 is necessary for initiation of TGF-β1-induced epithelial-mesenchymal transition in breast epithelial cells.
Jung H, Kim B, Moon BI, Oh ES.
Mol Cell Biochem 423(1-2):21-28. Epub 2016 Oct 13. 2016
4KRT18
Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis.
Bettermann K, Mehta AK, Hofer EM, Wohlrab C, Golob-Schwarzl N, Svendova V, Schimek MG, Stumptner C, Thüringer A, Speicher MR, Lackner C, Zatloukal K, Denk H, Haybaeck J.
Oncotarget 7(45):73309-73322. doi: 10.18632/oncotarget.12325. 2016
5KRT18, KRT8
Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18.
Kakade PS, Budnar S, Kalraiya RD, Vaidya MM.
J Biol Chem 291(23):12003-13. doi: 10.1074/jbc.M116.728717. Epub 2016 Apr 8. 2016
6ARHGEF40, KRT18, KRT8, RHOA
Interplay between Solo and keratin filaments is crucial for mechanical force-induced stress fiber reinforcement.
Fujiwara S, Ohashi K, Mashiko T, Kondo H, Mizuno K.
Mol Biol Cell 27(6):954-66. doi: 10.1091/mbc.E15-06-0417. Epub 2016 Jan 28. 2016
7KRT18
Serum caspase-cleaved cytokeratin-18 levels and outcomes after aneurysmal subarachnoid hemorrhage.
Yuan ZG, Wang JL, Jin GL, Yu XB, Li JQ, Qiu TL, Dai RX.
J Neurol Sci 359(1-2):298-304. doi: 10.1016/j.jns.2015.11.020. Epub 2015 Nov 12. 2015
8KRT18
Correlation between serum cytokeratin-18 and the progression or regression of non-alcoholic fatty liver disease.
Kawanaka M, Nishino K, Nakamura J, Urata N, Oka T, Goto D, Suehiro M, Kawamoto H, Yamada G.
Ann Hepatol 14(6):837-44. doi: 10.5604/16652681.1171767. 2015
9KRT18, KRT8, TNF
Tumor necrosis factor-α confers cardioprotection through ectopic expression of keratins K8 and K18.
Papathanasiou S, Rickelt S, Soriano ME, Schips TG, Maier HJ, Davos CH, Varela A, Kaklamanis L, Mann DL, Capetanaki Y.
Nat Med 21(9):1076-84. doi: 10.1038/nm.3925. Epub 2015 Aug 17. 2015
10EGR1, KRT18
EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression.
Zhang H, Chen X, Wang J, Guang W, Han W, Zhang H, Tan X, Gu Y.
Sci Rep 4:5416. doi: 10.1038/srep05416. 2014
11KRT18
Cytokeratin 18 is not required for morphogenesis of developing prostates but contributes to adult prostate regeneration.
Zhang C, Guo Y, Cui J, Zhu HH, Gao WQ.
Biomed Res Int 2013:576472. doi: 10.1155/2013/576472. Epub 2013 Dec 30. 2013
12KRT18
Increased plasma levels of CK-18 as potential cell death biomarker in patients with HELLP syndrome.
John K, Wielgosz S, Schulze-Osthoff K, Bantel H, Hass R.
Cell Death Dis 4:e886. doi: 10.1038/cddis.2013.408. 2013
13KRT18
Serum cytokeratin-18 fragment levels are useful biomarkers for nonalcoholic steatohepatitis in children.
Feldstein AE, Alkhouri N, De Vito R, Alisi A, Lopez R, Nobili V.
Am J Gastroenterol 108(9):1526-31. doi: 10.1038/ajg.2013.168. Epub 2013 Jun 11. 2013
14KRT18, KRT8
Keratin 8 is required for the maintenance of architectural structure in thymus epithelium.
Odaka C, Loranger A, Takizawa K, Ouellet M, Tremblay MJ, Murata S, Inoko A, Inagaki M, Marceau N.
PLoS One 8(9):e75101. doi: 10.1371/journal.pone.0075101. eCollection 2013. 2013
15CFTR, KRT18
Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.
Duan Y, Sun Y, Zhang F, Zhang WK, Wang D, Wang Y, Cao X, Hu W, Xie C, Cuppoletti J, Magin TM, Wang H, Wu Z, Li N, Huang P.
J Biol Chem 287(48):40547-59. doi: 10.1074/jbc.M112.403584. Epub 2012 Oct 8. 2012
16KRT18, KRT8
Keratin 8/18 regulation of cell stiffness-extracellular matrix interplay through modulation of Rho-mediated actin cytoskeleton dynamics.
Bordeleau F, Myrand Lapierre ME, Sheng Y, Marceau N.
PLoS One 7(6):e38780. doi: 10.1371/journal.pone.0038780. Epub 2012 Jun 7. 2012
17KRT18
Increased total cytokeratin-18 serum and urine levels in chronic kidney disease.
Roth GA, Lebherz-Eichinger D, Ankersmit HJ, Hacker S, Hetz H, Vukovich T, Perne A, Reiter T, Farr A, Hörl WH, Haas M, Krenn CG.
Clin Chim Acta 412(9-10):713-7. doi: 10.1016/j.cca.2010.12.030. Epub 2010 Dec 31. 2011
18KRT18, KRT8
Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma.
Yamashiro Y, Takei K, Umikawa M, Asato T, Oshiro M, Uechi Y, Ishikawa T, Taira K, Uezato H, Kariya K.
Biochem Biophys Res Commun 399(3):365-72. Epub 2010 Jul 24. 2010
19KRT18, CCRH
Mutation in keratin 18 induces mitochondrial fragmentation in liver-derived epithelial cells.
Kumemura H, Harada M, Yanagimoto C, Koga H, Kawaguchi T, Hanada S, Taniguchi E, Ueno T, Sata M.
Biochem Biophys Res Commun 367(1):33-40. Epub 2007 Dec 27. 2008
20KRT18
Injury-induced expression of cytokeratins 8 and 18 by vascular smooth muscle cells requires concurrent activation of cytoskeletal and growth factor receptors.
Moon MC, Yau L, Wright B, Zahradka P.
Can J Physiol Pharmacol 86(5):223-31. 2008
21KRT18
A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice.
Hesse M, Grund C, Herrmann H, Bröhl D, Franz T, Omary MB, Magin TM.
Exp Cell Res 313(14):3127-40. Epub 2007 May 25. 2007
22KRT18, KRT8
Identifying the role of specific motifs in the lens fiber cell specific intermediate filament phakosin.
Pittenger JT, Hess JF, Fitzgerald PG.
Invest Ophthalmol Vis Sci 48(11):5132-41. 2007
23KRT1, KRT10, KRT12, KRT13, KRT14, KRT14P, KRT15, KRT16, KRT17, KRT17P3, KRT18, KRT18P12, KRT18P16, KRT18P17, KRT18P18, KRT18P19, KRT18P20, KRT18P21, KRT18P22, KRT18P23, KRT18P24, KRT18P25, KRT18P26, KRT18P27, KRT18P28, KRT18P29, KRT18P30, KRT18P31, KRT18P32, KRT18P33, KRT18P34, KRT18P35, KRT18P36, KRT18P37, KRT18P38, KRT18P39, KRT18P40, KRT18P41, KRT18P42, KRT18P43, KRT18P44, KRT18P45, KRT18P46, KRT18P47, KRT18P48, KRT18P49, KRT18P5, KRT18P50, KRT18P8, KRT19, KRT19P1, KRT19P2, KRT19P3, KRT2, KRT20, KRT222, KRT23, KRT24, KRT25, KRT26, KRT27, KRT28, KRT3, KRT31, KRT32, KRT33, KRT33A, KRT34, KRT35, KRT36, KRT37, KRT38, KRT39, KRT4, KRT40, KRT5, KRT6A, KRT6B, KRT6C, KRT7, KRT71, KRT72, KRT73, KRT74, KRT75, KRT76, KRT77, KRT78, KRT79, KRT8, KRT80, KRT81, KRT82, KRT83, KRT84, KRT85, KRT86, KRT8P10, KRT8P13, KRT8P15, KRT8P17, KRT8P18, KRT8P19, KRT8P20, KRT8P21, KRT8P22, KRT8P23, KRT8P24, KRT8P25, KRT8P26, KRT8P27, KRT8P28, KRT8P29, KRT8P30, KRT8P5, KRT8P6, KRT8P7, KRT8P8, KRT8P9, KRT9, KRTAP19-8, KRTAP20-4
New consensus nomenclature for mammalian keratins.
Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW.
J Cell Biol 174(2):169-74. Epub 2006 Jul 10. 2006
24TCHP, KRT16, KRT18
Identification of trichoplein, a novel keratin filament-binding protein.
Nishizawa M, Izawa I, Inoko A, Hayashi Y, Nagata K, Yokoyama T, Usukura J, Inagaki M.
J Cell Sci 118(Pt 5):1081-90. 2005
25ELF5, KRT18
Epithelium-specific ets transcription factor 2 upregulates cytokeratin 18 expression in pulmonary epithelial cells through an interaction with cytokeratin 18 intron 1.
Yaniw D, Hu J.
Cell Res 15(6):423-9. 2005
26KRT18, KRT23, KRT24, KRT25
The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.
Rogers MA, Winter H, Langbein L, Bleiler R, Schweizer J.
Differentiation 72(9-10):527-40. 2004
27CCRH, KRT18
Mutation of human keratin 18 in association with cryptogenic cirrhosis.
Ku NO, et al.
J Clin Invest 99 : 19-23. 1997
28KRT18
Molecular characterization of a tissue-polypeptide-specific-antigen epitope and its relationship to human cytokeratin 18.
Rydlander L, et al.
Eur J Biochem 241 : 309-314. 1996
29PRPH, KRT18
Peripherin gene is linked to keratin 18 gene on human chromosome 12.
Blumenfeld A, et al.
Somat Cell Mol Genet 21 : 83-88. 1995
30KRT18
Localization of the gene for human simple epithelial keratin 18 to chromosome 12 using polymerase chain reaction.
Waseem A, et al.
Genomics 7 : 188-194. 1990
31KRT18
Cytokeratin expression in simple epithelia. I. Identification of mRNA coding for human cytokeratin no. 18 by a cDNA clone.
Romano V, Hatzfeld M, Magin TM, Zimbelmann R, Franke WW, Maier G, Ponstingl H.
Differentiation 30(3):244-53. 1986