| 1 | KPNB1, RANBP2, RANGAP1, XPO1
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| Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function.
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| Gilistro E, de Turris V, Damizia M, Verrico A, Moroni S, De Santis R, Rosa A, Lavia P.
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| J Cell Sci 130(15):2564-2578. doi: 10.1242/jcs.197905. Epub 2017 Jun 9.
2017
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| 2 | KPNB1
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| The importin protein karyopherin-β1 regulates the mice fibroblast-like synoviocytes inflammation via facilitating nucleus transportation of STAT3 transcription factor.
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| Sun C, Yu Z, Wang Y, Tao T.
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| Biochem Biophys Res Commun 471(4):553-9. doi: 10.1016/j.bbrc.2016.02.033.
2016
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| 3 | KPNB1, RELA
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| KPNβ1 promotes palmitate-induced insulin resistance via NF-κB signaling in hepatocytes.
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| Wang S, Zhao Y, Xia N, Zhang W, Tang Z, Wang C, Zhu X, Cui S.
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| J Physiol Biochem 71(4):763-72. doi: 10.1007/s13105-015-0440-x.
2015
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| 4 | CRY1, KPNB1, PER1
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| KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.
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| Lee Y, Jang AR, Francey LJ, Sehgal A, Hogenesch JB.
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| Elife 4. doi: 10.7554/eLife.08647.
2015
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| 5 | IGFBP3, KPNB1, MTRNR2L1
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| Humanin Peptide Binds to Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) and Regulates Its Interaction with Importin-β.
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| Njomen E, Evans HG, Gedara SH, Heyl DL.
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| Protein Pept Lett 22(10):869-76.
2015
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| 6 | KPNB1
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| Suppression of the nuclear transporter-KPNβ1 expression inhibits tumor proliferation in hepatocellular carcinoma.
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| Yang L, Hu B, Zhang Y, Qiang S, Cai J, Huang W, Gong C, Zhang T, Zhang S, Xu P, Wu X, Liu J.
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| Med Oncol 32(4):128. doi: 10.1007/s12032-015-0559-1.
2015
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| 7 | KPNB1, NUP153
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| Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner.
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| Lowe AR, Tang JH, Yassif J, Graf M, Huang WY, Groves JT, Weis K, Liphardt JT.
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| Elife 4. doi: 10.7554/eLife.04052.
2015
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| 8 | KPNB1
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| Importin β1 mediates nuclear factor-κB signal transduction into the nuclei of myeloma cells and affects their proliferation and apoptosis.
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| Yan W, Li R, He J, Du J, Hou J.
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| Cell Signal 27(4):851-9. doi: 10.1016/j.cellsig.2015.01.013.
2015
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| 9 | KPNB1, NUP54, NUP58
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| Allosteric Regulation in Gating the Central Channel of the Nuclear Pore Complex.
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| Koh J, Blobel G.
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| Cell 161(6):1361-73. doi: 10.1016/j.cell.2015.05.013.
2015
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| 10 | EI24, KPNA2, KPNB1
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| The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain.
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| Lieu KG, Shim EH, Wang J, Lokareddy RK, Tao T, Cingolani G, Zambetti GP, Jans DA.
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| J Cell Biol 205(3):301-12. doi: 10.1083/jcb.201304055. 2014
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| 11 | KPNB1
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| Intracellular calcium levels can regulate Importin-dependent nuclear import.
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| Kaur G, Ly-Huynh JD, Jans DA.
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| Biochem Biophys Res Commun 450(1):812-7. doi: 10.1016/j.bbrc.2014.06.047.
2014
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| 12 | KPNB1, SNAI1
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| Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin β.
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| Choi S, Yamashita E, Yasuhara N, Song J, Son SY, Won YH, Hong HR, Shin YS, Sekimoto T, Park IY, Yoneda Y, Lee SJ.
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| Acta Crystallogr D Biol Crystallogr 70(Pt 4):1050-60. doi: 10.1107/S1399004714000972.
2014
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| 13 | KPNB1
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| Inhibition of the nuclear transporter, Kpnβ1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells.
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| Angus L, van der Watt PJ, Leaner VD.
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| Carcinogenesis 35(5):1121-31. doi: 10.1093/carcin/bgt491.
2014
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| 14 | IPO8, KPNA2, KPNB1, RELA, XPO7
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| KPNB1, XPO7 and IPO8 mediate the translocation ofNF-κB/p65 into the nucleus.
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| Liang P, Zhang H, Wang G, Li S, Cong S, Luo Y, Zhang B.
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| Traffic 14(11):1132-43. doi: 10.1111/tra.12097. 2013
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| 15 | KPNB1
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| The nuclear import receptor Kpnβ1 and its potential as an anticancer therapeutic target.
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| van der Watt PJ, Stowell CL, Leaner VD.
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| Crit Rev Eukaryot Gene Expr 23(1):1-10. Review.
2013
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| 16 | KPNB1, RANBP2, RANGAP1, XPO1
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| Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores.
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| Roscioli E, Di Francesco L, Bolognesi A, Giubettini M, Orlando S, Harel A, Schininà ME, Lavia P.
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| J Cell Biol 196(4):435-50. doi: 10.1083/jcb.201109104. Epub 2012 Feb 13.
2012
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| 17 | KPNB1
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| Subcellular knockout of importin β1 perturbs axonal retrograde signaling.
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| Perry RB, Doron-Mandel E, Iavnilovitch E, Rishal I, Dagan SY, Tsoory M, Coppola G, McDonald MK, Gomes C, Geschwind DH, Twiss JL, Yaron A, Fainzilber M.
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| Neuron 75(2):294-305. doi: 10.1016/j.neuron.2012.05.033.
2012
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| 18 | KPNB1, NUP153, TP53BP1
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| Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.
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| Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J.
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| Cell Death Differ 19(5):798-807. doi: 10.1038/cdd.2011.150.
2012
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| 19 | KPNB1, RANBP2
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| Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.
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| Hamada M, Haeger A, Jeganathan KB, van Ree JH, Malureanu L, Wälde S, Joseph J, Kehlenbach RH, van Deursen JM.
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| J Cell Biol 194(4):597-612. 2011
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| 20 | CSE1L, KPNB1, XPO1, XPOT
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| Nuclear export complexes in the frame.
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| Cook AG, Conti E.
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| Curr Opin Struct Biol 20(2):247-52. doi: 10.1016/j.sbi.2010.01.012. Epub 2010 Feb 18. Review.
2010
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| 21 | KPNB1, XPO1
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| The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.
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| van der Watt PJ, Maske CP, Hendricks DT, Parker MI, Denny L, Govender D, Birrer MJ, Leaner VD.
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| Int J Cancer 124(8):1829-40.
2009
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| 22 | AHCTF1, KPNB1, NUP107, NUP160
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| Importin beta regulates the seeding of chromatin with initiation sites for nuclear pore assembly.
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| Rotem A, Gruber R, Shorer H, Shaulov L, Klein E, Harel A.
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| Mol Biol Cell 20(18):4031-42. doi: 10.1091/mbc.E09-02-0150.
2009
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| 23 | KPNB1
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| Nuclear import time and transport efficiency depend on importin beta concentration.
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| Yang W, Musser SM.
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| J Cell Biol 174(7):951-61. Epub 2006 Sep 18.
2006
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| 24 | AP1S1, ATP6V1D, BM22, CASP8AP2, CDC16, CDC27, CENPE, CLDN16, CMTM4, CYTH3, DDX5, DHX8, EIF3A, EIF3H, EIF4A3, GALNT5, ITPR1, KIF11, KPNB1, LSM6, MFAP1, NCAPD3, NCAPG2, RBM19, RRM2, SART1, SNRPA1, SNRPB, SNW1, SPC25, VCP, ZDHHC5
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| An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division.
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| Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, Drechsel D, Fischer S, Konstantinova I, Habermann B, Grabner H, Yaspo ML, Himmelbauer H, Korn B, Neugebauer K, Pisabarro MT, Buchholz F.
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| Nature 432(7020):1036-40. 2004
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| 25 | KPNA4, KPNB1
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| Assignment of KPNA4 and KPNB1 encoding karyopherin alpha 4 and beta 1 to human chromosome bands 11q22 and 17q21 respectively, by in situ hybridization.
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| Ayala-Madrigal ML, Doerr S, Ramirez-Duenas ML, Hansmann I.
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| Cytogenet Cell Genet 89(3-4):258-9. No abstract available. 2000
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| 26 | KPNB1, SNUPN
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| CRM1-mediated recycling of snurportin 1 to the cytoplasm.
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| Paraskeva E, Izaurralde E, Bischoff FR, Huber J, Kutay U, Hartmann E, Lührmann R, Görlich D.
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| J Cell Biol 145(2):255-64.
1999
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| 27 | KPNB1
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| Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope.
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| Gorlich D, Kostka S, Kraft R, Dingwall C, Laskey RA, Hartmann E, Prehn S.
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| Curr Biol 5(4):383-92. 1995
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| 28 | KPNB1
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| Sequence and characterization of cytoplasmic nuclear protein import factor p97.
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| Chi NC, Adam EJ, Adam SA.
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| J Cell Biol 130(2):265-74. 1995
|