1 | KPNA3
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| Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
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| Sowa AS, Martin E, Martins IM, Schmidt J, Depping R, Weber JJ, Rother F, Hartmann E, Bader M, Riess O, Tricoire H, Schmidt T.
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| Proc Natl Acad Sci U S A 115(11):E2624-E2633. doi: 10.1073/pnas.1716071115. Epub 2018 Feb 23.
2018
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2 | KPNA3, KPNA4, MECP2
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| Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2.
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| Lyst MJ, Ekiert R, Guy J, Selfridge J, Koerner MV, Merusi C, De Sousa D, Bird A.
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| Cell Rep 24(9):2213-2220. doi: 10.1016/j.celrep.2018.07.099.
2018
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3 | ADARB1, KPNA3
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| Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development.
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| Behm M, Wahlstedt H, Widmark A, Eriksson M, Öhman M.
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| J Cell Sci 130(4):745-753. doi: 10.1242/jcs.200055. Epub 2017 Jan 12.
2017
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4 | KPNA3, KPNA4, MECP2
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| Karyopherin α 3 and karyopherin α 4 proteins mediate the nuclear import of methyl-CpG binding protein 2.
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| Baker SA, Lombardi LM, Zoghbi HY.
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| J Biol Chem 290(37):22485-93. doi: 10.1074/jbc.M115.658104. Epub 2015 Aug 5.
2015
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5 | KPNA3
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| The nuclear import factor importin α4 can protect against oxidative stress.
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| Young JC, Ly-Huynh JD, Lescesen H, Miyamoto Y, Browne C, Yoneda Y, Koopman P, Loveland KL, Jans DA.
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| Biochim Biophys Acta 1833(10):2348-56. doi: 10.1016/j.bbamcr.2013.06.007. Epub 2013 Jun 14.
2013
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6 | KPNA3
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| The Drosophila importin-α3 is required for nuclear import of notch in vivo and it displays synergistic effects with notch receptor on cell proliferation.
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| Sachan N, Mishra AK, Mutsuddi M, Mukherjee A.
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| PLoS One 8(7):e68247. doi: 10.1371/journal.pone.0068247. Print 2013.
2013
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7 | KPNA3
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| KPNA3 variation is associated with schizophrenia, major depression, opiate dependence and alcohol dependence.
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| Morris CP, Baune BT, Domschke K, Arolt V, Swagell CD, Hughes IP, Lawford BR, McD Young R, Voisey J.
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| Dis Markers 33(4):163-70. doi: 10.3233/DMA-2012-0921.
2012
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8 | KPNA3
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| Subcellular distribution of importins correlates with germ cell maturation.
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| Hogarth CA, Jans DA, Loveland KL.
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| Dev Dyn 236(8):2311-20.
2007
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9 | KPNA3, RANBP5
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| A combined effect of the KPNA3 and KPNB3 genes on susceptibility to schizophrenia.
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| Zhang H, Ju G, Wei J, Hu Y, Liu L, Xu Q, Chen Y, Sun Z, Liu S, Yu Y, Guo Y, Shen Y.
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| Neurosci Lett 402(1-2):173-5. Epub 2006 Apr 27. 2006
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10 | KPNA3
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| The KPNA3 gene may be a susceptibility candidate for schizophrenia.
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| Wei J, Hemmings GP.
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| Neurosci Res 52(4):342-6. 2005
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11 | KPNA1, KPNA2, KPNA3
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| Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
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| Conti E, Uy M, Leighton L, Blobel G, Kuriyan J.
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| Cell 94(2):193-204. 1998
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12 | KPNA3
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| Isolation and mapping of karyopherin alpha 3 (KPNA3), a human gene that is highly homologous to genes encoding Xenopus importin, yeast SRP1 and human RCH1.
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| Takeda S, Fujiwara T, Shimizu F, Kawai A, Shinomiya K, Okuno S, Ozaki K, Katagiri T, Shimada Y, Nagata M, Watanabe T, Takaichi A, Kuga Y, Suzuki M, Hishigaki H, Takahashi E, Shin S, Nakamura Y, Hirai Y.
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| Cytogenet Cell Genet 76(1-2):87-93. 1997
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13 | KPNA1, KPNA2, KPNA3
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| A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus.
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| Gorlich D, Henklein P, Laskey RA, Hartmann E.
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| EMBO J 15(8):1810-7. 1996
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14 | KPNA3
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| Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes.
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| Moroianu J, et al.
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| Proc Natl Acad Sci U S A 92 : 2008-2011. 1995
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15 | APC, CTNNB1, CTNND1, JUP, KPNA3, ARVCF, CTNND2, KPNA2, PKP4, PKP1, PKP2, SPAG6
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| A repeating amino acid motif shared by proteins with diverse cellular roles.
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| Peifer M, et al.
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| Cell 76(5):789-91. No abstract available 1994
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