| 1 | KLK5, KLK7, SPINK5
|
| Toll-like receptor signaling induces the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes.
|
| Sugimoto S, Morizane S, Nomura H, Kobashi M, Sugihara S, Iwatsuki K.
|
| J Dermatol Sci 92(2):181-187. doi: 10.1016/j.jdermsci.2018.09.001. Epub 2018 Sep 15.
2018
|
| 2 | KLK14, KLK5, KLK7, SERPINA12
|
| Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
|
| Ulbricht D, Tindall CA, Oertwig K, Hanke S, Sträter N, Heiker JT.
|
| Biol Chem 399(9):1079-1084. doi: 10.1515/hsz-2018-0108.
2018
|
| 3 | CCL14, KLK5, KLK8
|
| Kallikrein-related peptidases are activators of the CC chemokine CCL14.
|
| Grünberg M, Quandt D, Cynis H, Demuth HU, Kindermann A, Magdolen V, Forssmann WG, Seliger B, Mägert HJ.
|
| Eur J Immunol 48(9):1592-1594. doi: 10.1002/eji.201747452. Epub 2018 Aug 22.
2018
|
| 4 | KLK5, KLK7
|
| KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
|
| Kasparek P, Ileninova Z, Zbodakova O, Kanchev I, Benada O, Chalupsky K, Brattsand M, Beck IM, Sedlacek R.
|
| PLoS Genet 13(1):e1006566. doi: 10.1371/journal.pgen.1006566. eCollection 2017 Jan.
2017
|
| 5 | KLK5, KLK7, PI3, SPINK5
|
| Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models.
|
| McGovern JA, Meinert C, de Veer SJ, Hollier BG, Parker TJ, Upton Z.
|
| Br J Dermatol 176(1):145-158. doi: 10.1111/bjd.14879. Epub 2016 Dec 22.
2017
|
| 6 | KLK5, KLK6, KLK7, KLK8, KLK9
|
| Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 - KLK9), using Next-generation sequencing.
|
| Adamopoulos PG, Kontos CK, Scorilas A.
|
| Sci Rep 7(1):17299. doi: 10.1038/s41598-017-16269-6.
2017
|
| 7 | KLK5, kLK7
|
| Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models.
|
| McGovern JA, Meinert C, de Veer SJ, Hollier BG, Parker TJ, Upton Z.
|
| Br J Dermatol 176(1):145-158. doi: 10.1111/bjd.14879. Epub 2016 Dec 22.
2017
|
| 8 | KLK14, KLK5, KLK7
|
| Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum.
|
| de Veer SJ, Furio L, Swedberg JE, Munro CA, Brattsand M, Clements JA, Hovnanian A, Harris JM.
|
| J Invest Dermatol 137(2):430-439. doi: 10.1016/j.jid.2016.09.017. Epub 2016 Sep 30.
2017
|
| 9 | KLK12, KLK5
|
| Cleavage activation of human-adapted influenza virus subtypes by kallikrein-related peptidases 5 and 12.
|
| Hamilton BS, Whittaker GR.
|
| J Biol Chem 288(24):17399-407. doi: 10.1074/jbc.M112.440362. Epub 2013 Apr 23.
2013
|
| 10 | DSG1, KLK5
|
| Kallikrein-5 promotes cleavage of desmoglein-1 and loss of cell-cell cohesion in oral squamous cell carcinoma.
|
| Jiang R, Shi Z, Johnson JJ, Liu Y, Stack MS.
|
| J Biol Chem 286(11):9127-35. Epub 2010 Dec 16.
2011
|
| 11 | KLK10, KLK5, KLK7, KLK8
|
| Multiple kallikrein (KLK 5, 7, 8, and 10) expression in squamous cell carcinoma of the oral cavity.
|
| Pettus JR, Johnson JJ, Shi Z, Davis JW, Koblinski J, Ghosh S, Liu Y, Ravosa MJ, Frazier S, Stack MS.
|
| Histol Histopathol 24(2):197-207.
2009
|
| 12 | KLK5, KLK7
|
| Parallel underexpression of kallikrein 5 and kallikrein 7 mRNA in breast malignancies.
|
| Li X, Liu J, Wang Y, Zhang L, Ning L, Feng Y.
|
| Cancer Sci 100(4):601-7.PMID: 19453546 2009
|
| 13 | KLK1, KLK13, KLK14, KLK2, KLK5, KLK6
|
| Association between kallikrein-related peptidases (KLKs) and macroscopic indicators of semen analysis: their relation to sperm motility.
|
| Emami N, Scorilas A, Soosaipillai A, Earle T, Mullen B, Diamandis EP.
|
| Biol Chem 390(9):921-9.PMID: 19558318 2009
|
| 14 | HGFAC, KLK4, KLK5
|
| Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases.
|
| Mukai S, Fukushima T, Naka D, Tanaka H, Osada Y, Kataoka H.
|
| FEBS J 275(5):1003-17. Epub 2008 Jan 25.
2008
|
| 15 | KLK4, KLK5, KLK6, KLK7
|
| Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7.
|
| Debela M, Beaufort N, Magdolen V, Schechter NM, Craik CS, Schmitt M, Bode W, Goettig P.
|
| Biol Chem 389(6):623-32. Review.PMID: 18627343 2008
|
| 16 | KLK1, KLK5, KLK6, KLK13, KLK14
|
| A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation.
|
| Borgono CA, Michael IP, Komatsu N, Jayakumar A, Kapadia R, Clayman GL, Sotiropoulou G, Diamandis EP.
|
| J Biol Chem 282(6):3640-52. Epub 2006 Dec 11. 2007
|
| 17 | KLK5, SPINK5
|
| LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction.
|
| Deraison C, Bonnart C, Lopez F, Besson C, Robinson R, Jayakumar A, Wagberg F, Brattsand M, Hachem JP, Leonardsson G, Hovnanian A.
|
| Mol Biol Cell 18(9):3607-19. Epub 2007 Jun 27.
2007
|
| 18 | KLK5, KLK6, KLK8, KLK9
|
| Association of KLK5 overexpression with invasiveness of urinary bladder carcinoma cells.
|
| Shinoda Y, Kozaki K, Imoto I, Obara W, Tsuda H, Mizutani Y, Shuin T, Fujioka T, Miki T, Inazawa J.
|
| Cancer Sci 98(7):1078-86. Epub 2007 Apr 24.PMID: 17459052 2007
|
| 19 | KLK13, KLK2, KLK3, KLK5, KLK6, KLK7, KLK8
|
| Distribution of 15 human kallikreins in tissues and biological fluids.
|
| Shaw JL, Diamandis EP.
|
| Clin Chem 53(8):1423-32. Epub 2007 Jun 15.PMID: 17573418 2007
|
| 20 | KLK5, KLK7, KLK14
|
| Kallikrein-related peptidase 14 may be a major contributor to trypsin-like proteolytic activity in human stratum corneum.
|
| Stefansson K, Brattsand M, Ny A, Glas B, Egelrud T.
|
| Biol Chem 387(6):761-8. 2006
|
| 21 | SPINK5, KLK5, KLK7
|
| LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum.
|
| Ishida-Yamamoto A, Deraison C, Bonnart C, Bitoun E, Robinson R, O'Brien TJ, Wakamatsu K, Ohtsubo S, Takahashi H, Hashimoto Y, Dopping-Hepenstal PJ, McGrath JA, Iizuka H, Richard G, Hovnanian A.
|
| J Invest Dermatol 124(2):360-6. 2005
|
| 22 | KLK5, KLK7
|
| KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer.
|
| Planque C, de Monte M, Guyetant S, Rollin J, Desmazes C, Panel V, Lemarie E, Courty Y.
|
| Biochem Biophys Res Commun 329(4):1260-6. 2005
|
| 23 | KLK5
|
| The human kallikrein protein 5 (hK5) is enzymatically active, glycosylated and forms complexes with two protease inhibitors in ovarian cancer fluids.
|
| Yousef GM, Kapadia C, Polymeris ME, Borgono C, Hutchinson S, Wasney GA, Soosaipillai A, Diamandis EP.
|
| Biochim Biophys Acta 1628(2):88-96. 2003
|
| 24 | KLK5, NT5C3A, RP9
|
| Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa.
|
| Keen TJ, Hims MM, McKie AB, Moore AT, Doran RM, Mackey DA, Mansfield DC, Mueller RF, Bhattacharya SS, Bird AC, Markham AF, Inglehearn CF.
|
| Eur J Hum Genet 10(4):245-9. 2002
|
| 25 | KLK10, KLK11, KLK12, KLK13, KLK14, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
|
| The New Human Kallikrein Gene Family: Implications in Carcinogenesis.
|
| Diamandis EP, Yousef GM, Luo I, Magklara I, Obiezu CV.
|
| Trends Endocrinol Metab 11(2):54-60. 2000
|
| 26 | KLK1, KLK10, KLK11, KLK12, KLK13, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
|
| Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.
|
| Harvey TJ, Hooper JD, Myers SA, Stephenson SA, Ashworth LK, Clements JA.
|
| J Biol Chem 275(48):37397-406.
2000
|
| 27 | KLK5
|
| The new kallikrein-like gene, KLK-L2. Molecular characterization, mapping, tissue expression, and hormonal regulation.
|
| Yousef GM, Diamandis EP.
|
| J Biol Chem 274(53):37511-6. 1999
|
| 28 | KLK5
|
| Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation.
|
| Brattsand M, Egelrud T.
|
| J Biol Chem 274(42):30033-40. 1999
|