| 1 | KLK2, KLK3, KLK4, kLK11
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| Activation and activity of glycosylated KLKs 3, 4 and 11.
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| Guo S, Briza P, Magdolen V, Brandstetter H, Goettig P.
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| Biol Chem 399(9):1009-1022. doi: 10.1515/hsz-2018-0148.
2018
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| 2 | HPN, KLK14, KLK4, MMP3, TMPRSS2
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| Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
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| Reid JC, Matsika A, Davies CM, He Y, Broomfield A, Bennett NC, Magdolen V, Srinivasan B, Clements JA, Hooper JD.
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| Am J Cancer Res 7(11):2257-2274. eCollection 2017.
2017
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| 3 | AMTN, KLK4
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| Maturation stage enamel malformations in Amtn and Klk4 null mice
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| Núñez SM, Chun YP, Ganss B, Hu Y, Richardson AS, Schmitz JE, Fajardo R, Yang J, Hu JC, Simmer JP.
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| Matrix Biol. May-Jul;52-54:219-233. doi: 10.1016/j.matbio.2015.11.007. Epub 2015 Nov 24 2016
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| 4 | AMELX, DLX3, ENAM, KLK4, ODAM
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| Transcriptional factor DLX3 promotes the gene expression of enamel matrix proteins during amelogenesis.
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| Zhang Z, Tian H, Lv P, Wang W, Jia Z, Wang S, Zhou C, Gao X.
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| PLoS One 10(3):e0121288. doi: 10.1371/journal.pone.0121288. 2015
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| 5 | KLK4, MMP20
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| MMP20, KLK4, and MMP20/KLK4 double null mice define roles for matrix proteases during dental enamel formation
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| Hu Y, Smith CE, Richardson AS, Bartlett JD, Hu JC, Simmer JP.
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| Mol Genet Genomic Med. Dec 20;4(2):178-96. doi: 10.1002/mgg3.194. 2015
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| 6 | KLK4, MMP20
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| MMP20 and KLK4 activation and inactivation interactions in vitro
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| Yamakoshi Y, Simmer JP, Bartlett JD, Karakida T, Oida S
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| Arch Oral Biol. Nov;58(11):1569-77. doi: 10.1016/j.archoralbio.2013.08.005. Epub 2013 Aug 18. 2013
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| 7 | KLK4
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| Expression analysis and study of KLK4 in benign and malignant breast tumours.
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| Papachristopoulou G, Avgeris M, Scorilas A.
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| Thromb Haemost 101(2):381-7.PMID: 19190825 2009
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| 8 | KLK4
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| Hypomaturation enamel defects in Klk4 knockout/LacZ knockin mice.
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| Simmer JP, Hu Y, Lertlam R, Yamakoshi Y, Hu JC.
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| J Biol Chem 284(28):19110-21. Epub 2009 May 6.PMID: 19578120 2009
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| 9 | CTSC, KLK4
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| DPPI may activate KLK4 during enamel formation.
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| Tye CE, Pham CT, Simmer JP, Bartlett JD.
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| J Dent Res 88(4):323-7.PMID: 19407151 2009
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| 10 | AIH1, AIH2, AIPH1, AIPH2, AMELX, ENAM, KLK4, MMP20
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| Human and mouse enamel phenotypes resulting from mutation or altered expression of AMEL, ENAM, MMP20 and KLK4.
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| Wright JT, Hart TC, Hart PS, Simmons D, Suggs C, Daley B, Simmer J, Hu J, Bartlett JD, Li Y, Yuan ZA, Seow WK, Gibson CW.
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| Cells Tissues Organs 189(1-4):224-9. Epub 2008 Aug 19. 2009
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| 11 | AI1C, AIH1, AIH2, AIH3, AIHHT, AIPH1, AIPH2, AMELX, AXIN1, DD2, DGI1, DLX3, DSPP, ENAM, FTA1, FTACC, KLK4, MMP20, MSX1, OLD, PAX9, STHAG5, ZNF22
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| The genetic basis of inherited anomalies of the teeth. Part 1: clinical and molecular aspects of non-syndromic dental disorders.
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| Bailleul-Forestier I, Molla M, Verloes A, Berdal A.
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| Eur J Med Genet 51(4):273-91. Epub 2008 Mar 26. Review.
2008
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| 12 | HGFAC, KLK4, KLK5
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| Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases.
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| Mukai S, Fukushima T, Naka D, Tanaka H, Osada Y, Kataoka H.
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| FEBS J 275(5):1003-17. Epub 2008 Jan 25.
2008
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| 13 | KLK4, KLK5, KLK6, KLK7
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| Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7.
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| Debela M, Beaufort N, Magdolen V, Schechter NM, Craik CS, Schmitt M, Bode W, Goettig P.
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| Biol Chem 389(6):623-32. Review.PMID: 18627343 2008
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| 14 | KLK4
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| Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins.
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| Obiezu CV, Michael IP, Levesque MA, Diamandis EP.
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| Biol Chem 387(6):749-59. 2006
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| 15 | KLK4
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| Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells.
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| Veveris-Lowe TL, Lawrence MG, Collard RL, Bui L, Herington AC, Nicol DL, Clements JA.
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| Endocr Relat Cancer 12(3):631-43. 2005
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| 16 | KLK4
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| Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms.
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| Dong Y, Bui LT, Odorico DM, Tan OL, Myers SA, Samaratunga H, Gardiner RA, Clements JA.
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| Endocr Relat Cancer 12(4):875-89. 2005
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| 17 | AIPH1, KLK4
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| Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta.
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| Hart PS, Hart TC, Michalec MD, Ryu OH, Simmons D, Hong S, Wright JT.
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| J Med Genet 41(7):545-9. No abstract available. 2004
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| 18 | KLK4
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| Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer.
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| Xi Z, Klokk TI, Korkmaz K, Kurys P, Elbi C, Risberg B, Danielsen H, Loda M, Saatcioglu F.
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| Cancer Res 64(7):2365-70. 2004
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| 19 | KLK4 , TGIF2, TSG12C, TSG11E, TSG13A, TSG17A, LOH18CR1, TSG20A, TSG4E, TSG8A
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| Cytogenetics and molecular genetics of ovarian cancer.
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| Wang N.
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| Am J Med Genet 115(3):157-63. 2002
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| 20 | KLK4
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| Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE.
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| Myers SA, Clements JA.
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| J Clin Endocrinol Metab 86(5):2323-6. 2001
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| 21 | KLK4
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| Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the kallikrein family: intracellular localization, alternative cDNA forms, and Regulation by multiple hormones.
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| Korkmaz KS, Korkmaz CG, Pretlow TG, Saatcioglu F.
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| DNA Cell Biol 20(7):435-45. 2001
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| 22 | KLK10, KLK11, KLK12, KLK13, KLK14, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| The New Human Kallikrein Gene Family: Implications in Carcinogenesis.
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| Diamandis EP, Yousef GM, Luo I, Magklara I, Obiezu CV.
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| Trends Endocrinol Metab 11(2):54-60. 2000
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| 23 | KLK4
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| Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors.
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| Hu JC, Zhang C, Sun X, Yang Y, Cao X, Ryu O, Simmer JP.
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| Gene 251(1):1-8. 2000
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| 24 | KLK4
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| An alternatively spliced variant of KLK4 expressed in prostatic tissue.
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| Obiezu CV, Diamandis EP.
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| Clin Biochem 33(7):599-600. No abstract available. 2000
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| 25 | KLK1, KLK10, KLK11, KLK12, KLK13, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.
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| Harvey TJ, Hooper JD, Myers SA, Stephenson SA, Ashworth LK, Clements JA.
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| J Biol Chem 275(48):37397-406.
2000
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| 26 | KLK4
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| Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression.
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| Nelson PS, et al.
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| Proc Natl Acad Sci U S A 96(6):3114-3119. 1999
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| 27 | KLK4
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| Assignment of serine protease 17 (PRSS17) to human chromosome bands 19q13.3-->q13.4 by in situ hybridization.
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| DuPont BR, et al.
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| Cytogenet Cell Genet 86(3-4):212-213. No abstract available 1999
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| 28 | KLK4
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| Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4.
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| Stephenson SA, Verity K, Ashworth LK, Clements JA.
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| J Biol Chem 274(33):23210-4 1999
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| 29 | KLK4
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| Prostase/KLK-L1 is a new member of the human kallikrein gene family, is expressed in prostate and breast tissues, and is hormonally regulated.
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| Yousef GM, Obiezu CV, Luo LY, Black MH, Diamandis EP.
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| Cancer Res 59(17):4252-6 1999
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