Citations for
1KLK2, KLK3, KLK4, kLK11
Activation and activity of glycosylated KLKs 3, 4 and 11.
Guo S, Briza P, Magdolen V, Brandstetter H, Goettig P.
Biol Chem 399(9):1009-1022. doi: 10.1515/hsz-2018-0148. 2018
2HPN, KLK14, KLK4, MMP3, TMPRSS2
Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
Reid JC, Matsika A, Davies CM, He Y, Broomfield A, Bennett NC, Magdolen V, Srinivasan B, Clements JA, Hooper JD.
Am J Cancer Res 7(11):2257-2274. eCollection 2017. 2017
3AMTN, KLK4
Maturation stage enamel malformations in Amtn and Klk4 null mice
Núñez SM, Chun YP, Ganss B, Hu Y, Richardson AS, Schmitz JE, Fajardo R, Yang J, Hu JC, Simmer JP.
Matrix Biol. May-Jul;52-54:219-233. doi: 10.1016/j.matbio.2015.11.007. Epub 2015 Nov 24 2016
4AMELX, DLX3, ENAM, KLK4, ODAM
Transcriptional factor DLX3 promotes the gene expression of enamel matrix proteins during amelogenesis.
Zhang Z, Tian H, Lv P, Wang W, Jia Z, Wang S, Zhou C, Gao X.
PLoS One 10(3):e0121288. doi: 10.1371/journal.pone.0121288. 2015
5KLK4, MMP20
MMP20, KLK4, and MMP20/KLK4 double null mice define roles for matrix proteases during dental enamel formation
Hu Y, Smith CE, Richardson AS, Bartlett JD, Hu JC, Simmer JP.
Mol Genet Genomic Med. Dec 20;4(2):178-96. doi: 10.1002/mgg3.194. 2015
6KLK4, MMP20
MMP20 and KLK4 activation and inactivation interactions in vitro
Yamakoshi Y, Simmer JP, Bartlett JD, Karakida T, Oida S
Arch Oral Biol. Nov;58(11):1569-77. doi: 10.1016/j.archoralbio.2013.08.005. Epub 2013 Aug 18. 2013
7KLK4
Expression analysis and study of KLK4 in benign and malignant breast tumours.
Papachristopoulou G, Avgeris M, Scorilas A.
Thromb Haemost 101(2):381-7.PMID: 19190825 2009
8KLK4
Hypomaturation enamel defects in Klk4 knockout/LacZ knockin mice.
Simmer JP, Hu Y, Lertlam R, Yamakoshi Y, Hu JC.
J Biol Chem 284(28):19110-21. Epub 2009 May 6.PMID: 19578120 2009
9CTSC, KLK4
DPPI may activate KLK4 during enamel formation.
Tye CE, Pham CT, Simmer JP, Bartlett JD.
J Dent Res 88(4):323-7.PMID: 19407151 2009
10AIH1, AIH2, AIPH1, AIPH2, AMELX, ENAM, KLK4, MMP20
Human and mouse enamel phenotypes resulting from mutation or altered expression of AMEL, ENAM, MMP20 and KLK4.
Wright JT, Hart TC, Hart PS, Simmons D, Suggs C, Daley B, Simmer J, Hu J, Bartlett JD, Li Y, Yuan ZA, Seow WK, Gibson CW.
Cells Tissues Organs 189(1-4):224-9. Epub 2008 Aug 19. 2009
11AI1C, AIH1, AIH2, AIH3, AIHHT, AIPH1, AIPH2, AMELX, AXIN1, DD2, DGI1, DLX3, DSPP, ENAM, FTA1, FTACC, KLK4, MMP20, MSX1, OLD, PAX9, STHAG5, ZNF22
The genetic basis of inherited anomalies of the teeth. Part 1: clinical and molecular aspects of non-syndromic dental disorders.
Bailleul-Forestier I, Molla M, Verloes A, Berdal A.
Eur J Med Genet 51(4):273-91. Epub 2008 Mar 26. Review. 2008
12HGFAC, KLK4, KLK5
Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases.
Mukai S, Fukushima T, Naka D, Tanaka H, Osada Y, Kataoka H.
FEBS J 275(5):1003-17. Epub 2008 Jan 25. 2008
13KLK4, KLK5, KLK6, KLK7
Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7.
Debela M, Beaufort N, Magdolen V, Schechter NM, Craik CS, Schmitt M, Bode W, Goettig P.
Biol Chem 389(6):623-32. Review.PMID: 18627343 2008
14KLK4
Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins.
Obiezu CV, Michael IP, Levesque MA, Diamandis EP.
Biol Chem 387(6):749-59. 2006
15KLK4
Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells.
Veveris-Lowe TL, Lawrence MG, Collard RL, Bui L, Herington AC, Nicol DL, Clements JA.
Endocr Relat Cancer 12(3):631-43. 2005
16KLK4
Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms.
Dong Y, Bui LT, Odorico DM, Tan OL, Myers SA, Samaratunga H, Gardiner RA, Clements JA.
Endocr Relat Cancer 12(4):875-89. 2005
17AIPH1, KLK4
Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta.
Hart PS, Hart TC, Michalec MD, Ryu OH, Simmons D, Hong S, Wright JT.
J Med Genet 41(7):545-9. No abstract available. 2004
18KLK4
Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer.
Xi Z, Klokk TI, Korkmaz K, Kurys P, Elbi C, Risberg B, Danielsen H, Loda M, Saatcioglu F.
Cancer Res 64(7):2365-70. 2004
19KLK4 , TGIF2, TSG12C, TSG11E, TSG13A, TSG17A, LOH18CR1, TSG20A, TSG4E, TSG8A
Cytogenetics and molecular genetics of ovarian cancer.
Wang N.
Am J Med Genet 115(3):157-63. 2002
20KLK4
Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE.
Myers SA, Clements JA.
J Clin Endocrinol Metab 86(5):2323-6. 2001
21KLK4
Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the kallikrein family: intracellular localization, alternative cDNA forms, and Regulation by multiple hormones.
Korkmaz KS, Korkmaz CG, Pretlow TG, Saatcioglu F.
DNA Cell Biol 20(7):435-45. 2001
22KLK10, KLK11, KLK12, KLK13, KLK14, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
The New Human Kallikrein Gene Family: Implications in Carcinogenesis.
Diamandis EP, Yousef GM, Luo I, Magklara I, Obiezu CV.
Trends Endocrinol Metab 11(2):54-60. 2000
23KLK4
Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors.
Hu JC, Zhang C, Sun X, Yang Y, Cao X, Ryu O, Simmer JP.
Gene 251(1):1-8. 2000
24KLK4
An alternatively spliced variant of KLK4 expressed in prostatic tissue.
Obiezu CV, Diamandis EP.
Clin Biochem 33(7):599-600. No abstract available. 2000
25KLK1, KLK10, KLK11, KLK12, KLK13, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.
Harvey TJ, Hooper JD, Myers SA, Stephenson SA, Ashworth LK, Clements JA.
J Biol Chem 275(48):37397-406. 2000
26KLK4
Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression.
Nelson PS, et al.
Proc Natl Acad Sci U S A 96(6):3114-3119. 1999
27KLK4
Assignment of serine protease 17 (PRSS17) to human chromosome bands 19q13.3-->q13.4 by in situ hybridization.
DuPont BR, et al.
Cytogenet Cell Genet 86(3-4):212-213. No abstract available 1999
28KLK4
Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4.
Stephenson SA, Verity K, Ashworth LK, Clements JA.
J Biol Chem 274(33):23210-4 1999
29KLK4
Prostase/KLK-L1 is a new member of the human kallikrein gene family, is expressed in prostate and breast tissues, and is hormonally regulated.
Yousef GM, Obiezu CV, Luo LY, Black MH, Diamandis EP.
Cancer Res 59(17):4252-6 1999