| 1 | FGFR2, KLK2
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| Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer.
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| Krook MA, Barker H, Chen HZ, Reeser JW, Wing MR, Martin D, Smith AM, Dao T, Bonneville R, Samorodnitsky E, Miya J, Freud AG, Monk JP, Clinton SK, Roychowdhury S.
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| Prostate Cancer Prostatic Dis 22(4):624-632. doi: 10.1038/s41391-019-0145-2. Epub 2019 May 1.
2019
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| 2 | KLK10, KLK15, KLK2, KLK3, KLK6, KLK7, KLK8
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| Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
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| Tailor PD, Kodeboyina SK, Bai S, Patel N, Sharma S, Ratnani A, Copland JA, She JX, Sharma A.
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| Oncotarget 9(25):17876-17888. doi: 10.18632/oncotarget.24947. eCollection 2018 Apr 3.
2018
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| 3 | KLK2, KLK3, KLK4, kLK11
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| Activation and activity of glycosylated KLKs 3, 4 and 11.
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| Guo S, Briza P, Magdolen V, Brandstetter H, Goettig P.
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| Biol Chem 399(9):1009-1022. doi: 10.1515/hsz-2018-0148.
2018
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| 4 | KLK2, KLK3
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| A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity.
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| Guo S, Skala W, Magdolen V, Briza P, Biniossek ML, Schilling O, Kellermann J, Brandstetter H, Goettig P.
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| J Biol Chem 291(2):593-604. doi: 10.1074/jbc.M115.691097. Epub 2015 Nov 18.
2016
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| 5 | KLK2, KLK3
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| Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.
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| Skala W, Utzschneider DT, Magdolen V, Debela M, Guo S, Craik CS, Brandstetter H, Goettig P.
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| J Biol Chem 289(49):34267-83. doi: 10.1074/jbc.M114.598201. Epub 2014 Oct 16.
2014
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| 6 | KLK2, NCOA4
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| Human kallikrein 2 (KLK2) promotes prostate cancer cell growth via function as a modulator to promote the ARA70-enhanced androgen receptor transactivation.
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| Shang Z, Niu Y, Cai Q, Chen J, Tian J, Yeh S, Lai KP, Chang C.
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| Tumour Biol 35(3):1881-90.
2014
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| 7 | ATF7IP, KLK2
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| Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.
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| Jin G, Zheng SL, Lilja H, Kim ST, Tao S, Gao Z, Young T, Wiklund F, Feng J, Isaacs WB, Rittmaster RS, Gronberg H, Condreay LD, Sun J, Xu J.
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| Neoplasia 15(1):95-101.
2013
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| 8 | KLK2, KLK3
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| Kallikreins on Steroids: Structure, Function, and Hormonal Regulation of Prostate-Specific Antigen and the Extended Kallikrein Locus.
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| Lawrence MG, Lai J, Clements JA.
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| Endocr Rev ndocr Rev. 2010 Jan 26. [Epub ahead of print]PMID: 20103546 2010
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| 9 | KLK15, KLK2, KLK3
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| A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.
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| Parikh H, Deng Z, Yeager M, Boland J, Matthews C, Jia J, Collins I, White A, Burdett L, Hutchinson A, Qi L, Bacior JA, Lonsberry V, Rodesch MJ, Jeddeloh JA, Albert TJ, Halvensleben HA, Harkins TT, Ahn J, Berndt SI, Chatterjee N, Hoover R, Thomas G, Hunter DJ, Hayes RB, Chanock SJ, Amundadottir L.
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| Hum Genet 127(1):91-9. Epub 2009 Oct 13.PMID: 19823874 2010
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| 10 | KLK1, KLK13, KLK14, KLK2, KLK5, KLK6
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| Association between kallikrein-related peptidases (KLKs) and macroscopic indicators of semen analysis: their relation to sperm motility.
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| Emami N, Scorilas A, Soosaipillai A, Earle T, Mullen B, Diamandis EP.
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| Biol Chem 390(9):921-9.PMID: 19558318 2009
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| 11 | CANT1, ETV4, KLK2
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| Two unique novel prostate-specific and androgen-regulated fusion partners of ETV4 in prostate cancer.
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| Hermans KG, Bressers AA, van der Korput HA, Dits NF, Jenster G, Trapman J.
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| Cancer Res 68(9):3094-8.
2008
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| 12 | KLK2, KLK3
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| Development of peptides specifically modulating the activity of KLK2 and KLK3.
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| Koistinen H, Närvänen A, Pakkala M, Hekim C, Mattsson JM, Zhu L, Laakkonen P, Stenman UH.
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| Biol Chem 389(6):633-42. Review.PMID: 18627344 2008
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| 13 | KLK2, KLK3
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| Activity and stability of human kallikrein-2-specific linear and cyclic peptide inhibitors.
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| Pakkala M, Hekim C, Soininen P, Leinonen J, Koistinen H, Weisell J, Stenman UH, Vepsäläinen J, Närvänen A.
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| J Pept Sci 13(5):348-53.PMID: 17436344 2007
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| 14 | KLK13, KLK2, KLK3, KLK5, KLK6, KLK7, KLK8
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| Distribution of 15 human kallikreins in tissues and biological fluids.
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| Shaw JL, Diamandis EP.
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| Clin Chem 53(8):1423-32. Epub 2007 Jun 15.PMID: 17573418 2007
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| 15 | KLK2
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| Variants of the hK2 protein gene (KLK2) are associated with serum hK2 levels and predict the presence of prostate cancer at biopsy.
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| Nam RK, Zhang WW, Klotz LH, Trachtenberg J, Jewett MA, Sweet J, Toi A, Teahan S, Venkateswaran V, Sugar L, Loblaw A, Siminovitch K, Narod SA.
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| Clin Cancer Res 12(21):6452-8.
2006
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| 16 | KLK2
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| Human kallikrein-2 gene polymorphism is associated with the occurrence of prostate cancer.
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| Chiang CH, Hong CJ, Chang YH, Chang LS, Chen KK.
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| J Urol 173(2):429-32.
2005
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| 17 | KLK2, KLK3
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| Unusual alternative splicing within the human kallikrein genes KLK2 and KLK3 gives rise to novel prostate-specific proteins.
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| David A, Mabjeesh N, Azar I, Biton S, Engel S, Bernstein J, Romano J, Avidor Y, Waks T, Eshhar Z, Langer SZ, Lifschitz-Mercer B, Matzkin H, Rotman G, Toporik A, Savitsky K, Mintz L.
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| J Biol Chem 277(20):18084-90. Epub 2002 Feb 7.
2002
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| 18 | KLK1, KLK10, KLK11, KLK12, KLK13, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9
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| Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.
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| Harvey TJ, Hooper JD, Myers SA, Stephenson SA, Ashworth LK, Clements JA.
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| J Biol Chem 275(48):37397-406.
2000
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| 19 | KLK2, SERPINB6
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| Identification of a novel complex between human kallikrein 2 and protease inhibitor-6 in prostate cancer tissue.
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| Mikolajczyk SD, Millar LS, Marker KM, Rittenhouse HG, Wolfert RL, Marks LS, Charlesworth MC, Tindall DJ.
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| Cancer Res 59(16):3927-30 1999
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| 20 | KLK2
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| Identification of three new alternate human kallikrein 2 transcripts: evidence of long transcript and alternative splicing.
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| Liu XF, Essand M, Vasmatzis G, Lee B, Pastan I.
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| Biochem Biophys Res Commun 264(3):833-9 1999
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| 21 | KLKB1, KLK2
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| Prostate-specific antigen and new related markers for prostate cancer.
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| Daher R, et al.
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| Clin Chem Lab Med 36 : 671-681. 1998
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| 22 | KLK1, KLK2, KLK3, KLKB1
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| Refined mapping and colocalization of the human genes for prostate-specific antigen and pancreatic kallikrein to 19q13.3.
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| Winqvist R, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2026. 1991
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| 23 | KLK2
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| Localization of human glandular kallikrein-1 gene to chromosome 19q13.3-13.4 by in situ hybridization.
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| Qin H, et al.
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| Hum Hered 41 : 222-226. 1991
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| 24 | KLK1, KLK2, KLK3, KLKB1
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| Refined mapping and colocalization of the human prostate-specific antigen and pancreatic kallikrein genes to 19q13.3.
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| Winqvist R, et al.
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| Am J Hum Genet 47 : A265. 1990
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